3D Medical Printing for Natural Disaster and Military Applications

PUSHING THE BOUNDARIES OF CUSTOMIZED MEDICAL IMPLANTS

OSIRISBIOMED 3D, LLC™

As Seen In

Presented At

Bio-Medical - Impacts of Bio-Printing and Printed Customized Prosthetics, Implants, Surgical Guides & Teaching Aids; Estimated Market Potential for Educational and Hospital

May 2015 - The Issues and Challenges of Developing a 3D Medical Device Business

Keynote Speaker: 3D Printed Medical Device

MedVestors 2015

Winner Of

2nd Annual Veteran Entrepreneur “Shark Tank” Business Pitch

2015 WINNER

Inside 3D Printing Conference & Expo Start-up Competition

OSIRISBIOMEDICAL

The Process for Custom Implants

Today

6 days 2 days 8 days

16 days

Submit quote and initial implant design

Submit

Finalize implant design

Finalize

Manufacture and ship implant to customer

Manufacture


OSIRISBIOMEDICAL

Osiris is Leading3D Printing to Enable

Deployable Healthcare

Osiris Biomed 3D’s patent pending Instant Implants™ process will allow a patient to be scanned, a custom device or implant printed,

sterilized, and surgically implanted on the operating table, all in one surgery.

Scan Casualty3D Print,Verify, &

SterilizeImplant


Skull Implant

8-10 mins 15-90 mins 10-90 mins

How do we empower surgeons to create custom implants in the battlespace or disaster area?

CONEX


CONEX – aka Container Box- large standardized shipping container- allow for unitized cargo- designed and built for intermodal freight transport - can be used across different modes of transport

– from ship to rail to truck to air– without unloading and reloading their cargo

- cargo includes bulk cargo – gaseous, liquid, solid

Size: 8.5 ft (height) x 8.0 ft (width) x 20 or 40 ft (length)- cubic capacity: 1,169 ft3

- tare weight: 5,300 lbs- max gross weight: 67,000 lbs- can be stacked 12 high

Statistics:- 20.5 million exist worldwide

How it Works

Take data from a CT scan and turn it into a series of 3D models. If unavailable, able to utilize anatomic norms or contralateral side.

1

Display those models in an Osiris 3DTM Modeling that allows for manipulation of design

2

Take design and create an output file that allows device to be manufactured by a 3D printer

3


Government

Today's federal initiatives focus on reducing healthcare delivery costs.

We eliminate the middle man and the need for tens ofmillions of dollars in consingedstock while eliminating entire surgeries, in many cases.

Payer/Insurer

Offers huge savings by reducing the number of surgeries − fewer surgeries equals fewer complications.

Customized fit results in better outcomes than current “one size fits most” solutions− reducing the opportunity for implant failures due to poor fit.

DOD / FEMA

Instant Implants allow more wounded casualties to be treated over time, increasing the number of casualties that can be serviced by a single facility or surgeon.

Provider becomes the manufacturer, eliminating the “middle man” and allowing for on-site manufacturing at afraction of the cost of current offerings.

Avoids the need for storing millions of dollars worth of “off-the-shelf” stock

Surgeon

Shorter operative times, better fit and better outcomes.

Eliminates the need for plate-bending and manipulation of "off-the-shelf" implants (can waste 30 mins to several hours per surgical case).

- If it doesn’t fit, re-print!

Puts the surgeon in charge, allowing adaptation and innovation to happen in real time in the mobile operating room, rather than turning over control to large, state-side multinational corporations who will never meet the patient.

Patient/Casualty

Provides patient-specific custom implant fit – shown to improve clinical outcomes.

Eliminates entire surgeries, which reduces the risk of infection and complications and reduces recovery time.

OB3DTM saves wounded soldiers and victims of natural disasters. They can receive immediate care rather than being forced to endure dangerous evacuations to Level I trauma centers.

This has the potential to save lives and avoid morbidity associated with transporting casualties.

Instant Implants → Fulfills the Five P’s of Military Healthcare

OSIRISBIOMEDICAL

Cost Effectiveness table compared to current process costs

MODEL Ear Face Upper Extremity Skull

CURRENT

CAPABILITY

$1,800

2-4 weeks

$12,500

2-4 weeks

$20,000-$30,000

2-4 weeks

$10,000

2-4 weeks

OSIRIS$0.50

31 minutes

$0.73

43 minutes

$13.40

20 hours

$3.85

3 hours


Application Title: “HIGHLY MOBILE MILITARY MEDICAL 3D PRINTING CONEX TO CONSTRUCT A SURGICAL OPERATING ROOM”U.S. Provisional App. Serial No. 62/003,477, filed May 27, 2014

Application Title: “DATABASE AND MARKETPLACE FOR MEDICAL DEVICES”U.S. Provisional App. Serial No. 62/003,473, filed May 27, 2014

Competitive Cost Advantage

Better Fit+

Instant Delivery+

Lower Costs

Value Multiplied

OSIRISBIOMEDICAL


Better Fit+

Instant Delivery+

Lower Costs

Value Multiplied

APPLICATION Vessel ConduitsBony

DefectsUpper Extremity Skull

CURRENT

CAPABILITY

CASEVAC+tourn

quet

3 surgeries

6 weeks

CASEVAC + 4

surgeries

6-12 weeks

CASEVAC + 3

surgeries

3-6 weeks

OSIRIS Instant ImplantzTM 1 surgery

31 minutes

1 surgery

43 minutes

2 surgeries

20 hours

1 surgery

3 hours


Application Title: “HIGHLY MOBILE MILITARY MEDICAL 3D PRINTING CONEX TO CONSTRUCT A SURGICAL OPERATING ROOM”U.S. Provisional App. Serial No. 62/003,477, filed May 27, 2014

Application Title: “DATABASE AND MARKETPLACE FOR MEDICAL DEVICES”U.S. Provisional App. Serial No. 62/003,473, filed May 27, 2014

Time to Definitive Surgery

OSIRISBIOMEDICAL


EBM+

FDM+

SLS+

Autoclave

Lives Saved


Mobile Biomedical CONEX Fabrication Lab

Co-Located Scanning

Applications titled “CO-LOCATED SCANNING, PRINTING AND/OR MACHINING DEVICES FOR MEDICAL CONSTRUCTS”

U.S. Utility App. Serial No. 14/304,908, filed June 14, 2014

International Patent Application No. PCT/US/14/42434, filed June 14, 2014

Deployable CONEX FabLab

Application Title: “HIGHLY MOBILE MILITARY MEDICAL 3D PRINTING CONEX TO CONSTRUCT A SURGICAL OPERATING ROOM”

U.S. Provisional App. Serial No. 62/003,477, filed May 27, 2014

Medical Part Database and Marketplace

Application Title: “DATABASE AND MARKETPLACE FOR MEDICAL DEVICES”

U.S. Provisional App. Serial No. 62/003,473, filed May 27, 2014

Our Patented Process


Phase One Phase ThreePhase Two

Scaling theOpportunityin the U.S and Globally

CMF/Hand

InitialTarget

$74M

The global market

~$30B

Additive Manufacturing Market for Skeletal Fixation, Recon and Augmentation

$2.4B $2.9B

Full Additive Medical ManufacturingMarket


No matter how streamlined the medical supply chain it willbe very difficult to compete with on-site, combat or disaster customized patient-specific implant delivery.

Building:

- Conex: $5,000 - 1,500 (New vs. Used)

Per unit delivery cost:

Deployable CONEX Unit Cost


Manufacturing Machines:

- FDM: $9k - $15k

- EBM: $500k - $1.5M

- SLS: $125k - $350k

Building Materials:

- Durable Components: ($10,000)(desk, cabinet, cabinetry, materials)

$2,500

$1,000,000

$10,000

Total: $1,012,500($22,500 - $3MM)

PUSHING THE BOUNDARIES OF CUSTOMIZED MEDICAL IMPLANTS

OSIRIS

Contact: [email protected]: www.osirisbiomed.comPhone: (212) 706-0463

Thank You

BIOMED 3D, LLC™

Technology

3D Medical Printing for Natural Disaster and Military Applications