RNA Polymerase

Transcription

A

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

Transcription

Factors

A

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

Transcription

Factors

A

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

Transcription

Factors

Transcription

Factors

A

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

Transcription

FactorsA

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

Transcription

FactorsA

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

Transcription

FactorsA

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

Transcription

FactorsA

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

Transcription

FactorsA

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

Transcription

FactorsA

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

A

Transcription

FactorsA

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

A

U

Transcription

FactorsA

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

A

U

A

Transcription

FactorsA

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

A

U

A

G

Transcription

FactorsA

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

A

U

A

G

C

Transcription

FactorsA

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

A

U

A

G

C

A

Transcription

FactorsA

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

A

U

A

G

C

A

C

Transcription

FactorsA

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

A

U

A

G

C

A

C

Transcription

FactorsA

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

A

U

A

G

C

A

C

Transcription

FactorsA

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

A

U

A

G

C

A

C

Transcription

FactorsA

T

G

C

A

A

C

T

T

T

A

G

G

C

I’m RNA Polymerase

A

U

A

G

C

A

C

AAAAA

http://commons.wikimedia.org/wiki/File:DNA_exons_introns.gif

Ribosome

http://commons.wikimedia.org/wiki/File:3d_tRNA.png

http://com

mons.w

ikimedia.org/w

iki/File:TRNA_sekundaarstrukt.png

tRNA

TranslationA SiteP SiteE Site

A SiteP SiteE Site

U

A

A U A G

A SiteP SiteE Site

AminoAcid 1

U

U

A

A U A G

A SiteP SiteE Site

AminoAcid 1U

U

A

A U A G

A SiteP SiteE Site

AminoAcid 1

U UA

A U A G

A SiteP SiteE Site

AminoAcid 1

U UA

A U A G C

A SiteP SiteE Site

A U A G C A

AminoAcid 1

U UA

A SiteP SiteE Site

AminoAcid 1

U UA

A U A G C A C

C

U

GH

A SiteP SiteE Site

AminoAcid 1

U UA

A U A G C A C

Amino

Acid 2

C

U

GH

A SiteP SiteE Site

AminoAcid 1

U UA

A U A G C A C

AminoAcid 2

C

U

G

A SiteP SiteE Site

AminoAcid 1

U UA

A U A G C A C

AminoAcid 2C

U

G

A SiteP SiteE Site

AminoAcid 1

U UA

A U A G C A C

AminoAcid 2

C UG

A SiteP SiteE Site

AminoAcid 1

U UA

A U A G C A C

AminoAcid 2

C UG

A SiteP SiteE Site

AminoAcid 1

U UA

A U A G C A C

AminoAcid 2

C UG

A SiteP SiteE Site

AminoAcid 1

A U A G C A C

AminoAcid 2

C UGU UA

A SiteP SiteE Site

AminoAcid 1

A U A G C A C

AminoAcid 2

C UGU UA

A SiteP SiteE Site

AminoAcid 1

A U A G C A C A

AminoAcid 2

C UGU UA

A SiteP SiteE Site

AminoAcid 1

A U A G C A C A U

AminoAcid 2

C UGU UA

A SiteP SiteE Site

AminoAcid 1

A U A G C A C A U A

AminoAcid 2

C UGU UA

A SiteP SiteE Site

AminoAcid 1

A U A G C A C A U A

AminoAcid 2

C UGU

U

A

U

G

A SiteP SiteE Site

AminoAcid 1

A U A G C A C A U A

AminoAcid 2

C UG

U

U

A

U

G

A

AminoAcid 3

A SiteP SiteE Site

AminoAcid 1

A U A G C A C A U A

AminoAcid 2

C UG

U

A

U

G

A

AminoAcid 3

A SiteP SiteE Site

A U A G C A C A U A

AminoAcid 2

C UG

U

AminoAcid 1U

G

A

AminoAcid 3

A SiteP SiteE Site

A U A G C A C A U A

C UG

UG A

AminoAcid 3

AminoAcid 2

AminoAcid 1

A SiteP SiteE Site

A U A G C A C A U A

C UG

UG A

AminoAcid 3

AminoAcid 2

AminoAcid 1

A SiteP SiteE Site

A U A G C A C A U A

C UG

UG A

AminoAcid 3

Amino

Acid 2

Amino

Acid 1

A SiteP SiteE Site

A U A G C A C A U A

C UG

UG A

AminoAcid 3

Amino

Acid 2

Amino

Acid 1

A SiteP SiteE Site

A U A G C A C A U A G

C UG

UG A

AminoAcid 3

Amino

Acid 2

Amino

Acid 1

A SiteP SiteE Site

A U A G C A C A U A G C

C UG

UG AAminoAcid 3

Amino

Acid 2

Amino

Acid 1

A SiteP SiteE Site

A G C A C A U A G C A

UG A

AminoAcid 3

AminoAcid 2

AminoAcid 1

C UG

A SiteP SiteE Site

A G C A C A U A G C A

C

U

G

UG A

AminoAcid 3

AminoAcid 2

AminoAcid 1U

STOP

A SiteP SiteE Site

A G C A C A U A G C A

C

U

G

UG A

AminoAcid 3

AminoAcid 2

AminoAcid 1

C

U

STOP

A SiteP SiteE Site

A G C A C A U A G C AC

U

G

UG A

AminoAcid 3

AminoAcid 2

AminoAcid 1

C

U

G

STOP

A SiteP SiteE Site

A G C A C A U A G C A

C

U

G

UG A

AminoAcid 3

AminoAcid 2

AminoAcid 1

C

U

G

STOP

A SiteP SiteE Site

A G C A C A U A G C A

U

G

UG A

AminoAcid 3

AminoAcid 2

AminoAcid 1

CU G

STOP

A SiteP SiteE Site

A G C A C A U A G C A

AminoAcid 3

UG A

AminoAcid 2

AminoAcid 1

CU G

STOP

A SiteP SiteE Site

A G C A C A U A G C A

AminoAcid 3

UG A

Amino

Acid 2

Amino

Acid 1

CU G

STOP

A SiteP SiteE Site

A G C A C A U A G C A

UG A

AminoAcid 3

Amino

Acid 2

Amino

Acid 1

CU G

STOP

A SiteP SiteE Site

A G C A C A U A G C A

UG A

AminoAcid 3

Amino

Acid 2

Amino

Acid 1

CU G

STOP

A SiteP SiteE Site

A G C A C A U A G C A

UG A

AminoAcid 3

Amino

Acid 2

Amino

Acid 1

CU G

STOP

A SiteP SiteE Site

A G C A C A U A G C A

UG A

Amino

Acid 2

Amino

Acid 1

CU G

STOP

A SiteP SiteE Site

A G C A C A U A G C A

UG A

Amino

Acid 2

Amino

Acid 1

CU G

STOP

A SiteP SiteE Site

A G C A C A U A G C A

UG A

CU G

STOP

Humans: 20,000-25,000!

http://commons.wikimedia.org/wiki/File:Genes_and_bases_on_chromosomes.png

http://commons.wikimedia.org/wiki/File:DNA_exons_introns.gif