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Synthetic biology

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Universidad Autónoma de Nuevo LeónFacultad de Ciencias Biológicas

Licenciado en Biotecnología GenómicaPrimer semestre Grupo 413

Bioética – Dr. Carlos Jair Guerrero-García

• Martín Bernal López 1543619

• Eloisa Garza González 1636948

• Jennifer Ainara Godínez Pérez 1717821

• Celeste F. Gracia Rodríguez 1717817

• Erick Irving Hernández Villarreal 1634301

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Agenda

• Abstract

• Bioingeniería

• Biología sintética

• Biobricks

• Riesgos y beneficios

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El ensayo fue escrito por ZacharyRuss estudiante de primer añocursando la Carrera de Bioingenieríaen la Universidad de Maryland.

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Un bioingeniero es quién se ocupa de todos losaspectos tecnológicos relacionados de algunamanera en la medicina y la biología. Además, aligual que un biólogo o un médico, se encarga delestudio y el análisis de todos los organismos vivos.

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- Nobel Laureate and physicist Richard P. Feynman

La bioingeniería aún y con todos sus logros tiene quecrear vida para encajar en el mismo tipo de precisasespecificaciones que los ingenieros químicos tienen quehacer con moléculas y que los ingenieros mecánicostienen con las máquinas.

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“The newly introduced field of synthetic biology (synbio) represents a response to that problem.”

¿QUÉ ES?

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La base de la Biología Sintética son los biobricks, fragmentos de ADN que codifican para una característica biológica y que pueden ser combinados para formar circuitos complejos.

Los biobricks constituyen, por tanto, la unidad estándar y modular básica que realiza una función simple y permiten modificar el comportamiento de una célula sin la necesidad de conocer a priori el funcionamiento exacto del sistema. http://syntheticbiology.org/BioBricks.html

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The BioBricks project takes the former approach, and, bydesigning organisms using standardized building blocks, makesgenetic engineering easier and much more efficient. BioBricksprovide the potential to make biochemicals and pharmaceuticalsquickly and easily without having to worry about unforeseeninteractions between the drug genes and vestigial genes

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With complete control over the genomes of their organisms, synbioengineerscan introduce specific weaknesses into their organisms, such as adependency on a particular amino acid, so that lab experiments have littlechance of surviving in the wild. Without the noise data that naturalorganisms have in their genomes, synthetic organisms will also be verylimited in genetic variation and virtually unable to adapt to new conditions.

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While accidental harm is significant, in theage of terrorism in which we live, malice isalso an important factor in technologies.

There is even more risk to not using synthetic biology. Synthetic biology can produce organisms to clean up pollution and provide clean energy. Proteins and food can be created without wasting energy on a full-sized organism, providing cheap ways to make nutritious meals for millions.

Synbio is the opportunity to gain power over life and achieve the ultimate goal in engineering – to be so familiar with a part that its behavior can be modeled, predicted, and used; and the uses are limitless

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“The genetic code is 3.6 billion years old. It's time for a rewrite.”

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Guardian October 22, 2007

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June 4, 2007

6. http://www.grain.org/es/article/entries/1103-biologia-sintetica-el-futuro-de-la-vida-en-manos-de-los-cientificos

7. http://microbioun.blogspot.mx/2014/03/biologia-sintetica-para-que-construir.html

8. http://www.elmundo.es/ciencia/2014/05/07/536a6edae2704e7f278b4584.html