Our Genes Are Not Our DestinyThe Role of Genetics, Epigenetics, and Nutrigenomics in Autoimmunity Lifestyle Modifications

The Genes You Can’t Take Off: What is the Relationship between Autoimmunity and Genetics?

• Ritchie, M., Holzinger, E., Li, R., Pendergrass, S. & Kim, D. Methods of integrating data to uncover genotype-phenotype interactions. Nature Reviews Genetics (2015). http://www.nature.com/nrg/journal/v16/n2/abs/nrg3868.html

• Seldin, MF. The genetics of human autoimmune disease: A perspective on progress in the field and future directions. Journal of autoimmunity (2015). http://www.sciencedirect.com/science/article/pii/S0896841115300330

• Smilek, D. & Clair, W. Solving the puzzle of autoimmunity: critical questions. F1000Prime Reports 7, (2015). http://www.ncbi.nlm.nih.gov/pubmed/25750735

Change your Fate: What can Epigenetics do for Autoimmunity?

• Farh, K. et al. Genetic and epigenetic fine mapping of causal autoimmune disease variants. Nature 518, 337–43 (2015). http://www.nature.com/nature/journal/v518/n7539/full/nature13835.html

• Gupta, B. & Hawkins, D. Epigenomics of autoimmune diseases. Immunol Cell Biol

93, 271–276 (2015). http://www.nature.com/icb/journal/v93/n3/full/icb201518a.html

• Jeffries, MA & Sawalha, AH. Autoimmune disease in the epigenetic era: how has

epigenetics changed our understanding of disease and how can we expect the field to evolve? Expert review of clinical … (2014). http://www.pubfacts.com/detail/25534978/Autoimmune-disease-in-the-epigenetic-era:-how-has-epigenetics-changed-our-understanding-of-disease-a

Are We What We Eat Or Is What We Eat Who We Are?: Nutrigenomics and Autoimmunity

• Ferguson, LR. Nutrigenetics, nutrigenomics and inflammatory bowel diseases. Expert review of clinical immunology (2013). http://www.ncbi.nlm.nih.gov/pubmed/23971750

• Gibson, PR, Varney, J, Malakar, S & Muir, JG. Food Components and Irritable Bowel Syndrome. Gastroenterology (2015). at http://www.sciencedirect.com/science/article/pii/S0016508515001961

• Minich, D. M. & Bland, J. S. Personalized lifestyle medicine: relevance for nutrition and lifestyle recommendations. The Scientific World Journal 2013, (2013). http://www.ncbi.nlm.nih.gov/pubmed/23878520

• Xie, G, Li, X, Li, H & Jia, W. Toward personalized nutrition: comprehensive phytoprofiling and metabotyping. Journal of proteome research (2013). http://pubs.acs.org/doi/abs/10.1021/pr301222b

Our Genes Are Not Our Destiny

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Bonnie Feldman, DDS, MBABusiness Development for Digital Health