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Antibodies Newsflash January 2015
New Products
Ebola Antibodies
Veterinary Antibodies
New Antibody Data
Cystatin C Recombinant Fabs
S100 B Recombinant Fabs
Capabilities
Monoclonal antibodies
Polyclonal antibodies
Recombinant Fab antibodies
Quality Innovation Results Partnership
Be confident in your results when you
choose BBI’s monoclonal antibodies for
your next assay:
Tested in ELISA
Tested in lateral flow
Recommended pairings provided
Strong customer feedback
We have now introduced highly sensitive
recombinant Fab antibodies to improve
your next generation assays.
New this month:
veterinary antibodies for companion
and livestock animals
antibodies to detect deadly Ebola
virus strains
Why choose BBI?
Quick Links
NEW
Ebola Antibodies >
Veterinary Antibodies >
CDV Data >
Anti Swine IgG Data >
Cystatin C Affinity Data >
S100B Affinity Data >
Monoclonal Antibodies >
Polyclonal Antibodies >
Recombinant Fab
Antibodies >
How to Order >
NEW Ebola Antibodies
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Our new range of Ebola Sudan and Ebola Zaire monoclonal antibodies are now available,
suitable for lateral flow (rapid test) assays.
The antibodies can detect the current Ebola outbreak in West Africa.
We also provide a panel comprising 13 different monoclonal antibodies to the Zaire and
Sudan strains.
These Ebola virus antibodies were generated at Dstl Porton Down (the UK government
agency: Defence, Science and Technology Laboratory) and are manufactured and sold
under licence from the UK Secretary of State for Defence.
Antibodies to the Ebola Reston strain are available on request.
Marker Product Code Application
Ebola Sudan BM430-D1A1 Lateral Flow
Ebola Zaire BM431-M4B1 Lateral Flow
Ebola Zaire BM431-O9C2 Lateral Flow
Ebola Zaire BM431-V1D1 Lateral Flow
Ebola Zaire BM431-Z2G2 Lateral Flow
Ebola Sudan and Zaire BM435-PANEL Lateral Flow
NEW Veterinary Antibodies
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New range of veterinary antibodies targeted to a variety of companion and
livestock animals.
Tested in lateral flow with recommended matched pairings.
Marker Capture Antibody Detection Antibody
CDV (Canine Distemper Virus) BM417-D1A6 BM417-D1A6
Avian Influenza Virus H5 BM422-Z3D1 BM422-P6H1
FeLV BM419-E7A5 BM419-O6H1
Brucella LPS BM420-G9E1 BM420-M9D1
Giardia BM423-V5C5 BM423-V5C5
Enrofloxacin BM427-Z6C6 BM427-Z6C6
Goat IgG BM418-G7B1 or BM418-K5D1 BM418-G7B1 or BM418-K5D1
Canine IgM BM424-S6B1
BM424-T7H1
BM424-T7H1
BM424-S6B1
Swine IgG N/A BM425-S6H4
Chicken IgY BM421-P5G5 or BM421-M6B6 BM421-M6B6 or BM421-P5G5
GST (Glutathione S-transferase) N/A BM426-H9E9
Antibody Spotlight
CDV (Canine Distemper Virus) Antibody
Marker Capture
Antibody
Detection
Antibody
CDV BM417-D1A6
Antibody A
Antibody A
BM417-D1A6
Proven performance in Lateral Flow
Lane 1 - Commercially-used CDV pair (Antibody A & B)
Lane 2 - Negative sample
Lane 3 - Antibody A as capture, BM417-D1A6 as detection
Lane 4 - Negative sample
Lane 5 - BM417-D1A6 as capture, Antibody A as detection
Lane 6 – Negative sample
1 2 3 4 5 6
CDV is a viral disease affecting animals
such as dogs, ferrets and racoons which
is fatal in 50% of cases.
Images have not been altered for brightness or contrast.
BM417-D1A6 can be utilised as a capture or
detection antibody in lateral flow.
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Antibody Spotlight
Anti-Swine IgG Antibody
Gold-conjugated anti-swine IgG antibody
BM425-S6H4 was tested against a selection of
immobilised animal IgGs.
It detected Swine IgG, Canine IgG and Human
IgG.
Marker Detection Antibody
Anti-Swine IgG BM425-S6H4
Images have not been altered for brightness or contrast.
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Antibody Spotlight New Data – Cystatin C Recombinant Fab
affinity data
Biotinylated antigen was immobilised onto a streptavidin sensor. Ka, Kd and KD
measured on the Octet system.
Our Cystatin C (BR175-H4C8) recombinant Fab antibody has a picomolar
affinity of 226pM.
KD (nM)
0.226
Kon (1/Ms)
172800± 323
Kdis (1/s)
3.9 x 10-5 ±
2.43 x 10-7
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Antibody Spotlight New Data – Cystatin C Recombinant Fab
affinity data
Biotinylated antigen was immobilised onto a streptavidin sensor. Ka, Kd and KD
measured on the Octet system.
Our Cystatin C (BR175-G8D9) recombinant Fab antibody has a picomolar
affinity of 290pM.
KD (nM)
0.290
Kon (1/Ms)
123000 ± 109
Kdis (1/s)
3.56 x 10-5 ±
2.24 x 10-7
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Antibody Spotlight New Data – S100 Beta Recombinant Fab
affinity data
Biotinylated antigen was immobilised onto a streptavidin sensor. Ka, Kd and KD
measured on the Octet system.
Our S100 Beta (BR332-F5H7) recombinant Fab antibody has a picomolar
affinity of 554pM.
KD (nM)
0.554
Kon (1/Ms)
329300 ± 105
Kdis (1/s)
1.82 x 10-5 ±
2.11 x 10-7
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Antibody Spotlight New Data – S100 Beta Recombinant Fab
affinity data
Biotinylated antigen was immobilised onto a streptavidin sensor. Ka, Kd and KD
measured on the Octet system.
Our S100 Beta (BR332-G4H7) recombinant Fab antibody has a picomolar
affinity of 347pM.
KD (nM)
0.347
Kon (1/Ms)
205300 ± 143
Kdis (1/s)
7.12 x 10-5 ±
1.78 x 10-7
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Our Capabilities | Monoclonal Antibodies
Cardiac Infectious Disease Listeria Pregnancy
CK-MB C. difficile Toxin A Malaria HRP2 AFP
D-Dimer C. difficile Toxin B Malaria LHD (pan)
Myoglobin Chikungunya Malaria LDH (Pf & Pv) Veterinary
Troponin I Dengue NS1 Norovirus Canine Distemper
Ebola Reston PBP2a Virus
Diabetes Ebola Sudan TB Avian Influenza H5
Hb Ebola Zaire FeLV
HbA1c HAV Tumour Brucella LPS
H. pylori CA125 Enrofloxacin
Drugs of abuse HAV CA15-3 Goat IgG
THCΔ9 HBV CA19-9 Canine IgM
Hepatitis B Calcitonin Chicken IgY
Hormones HIV p24 GST
Progesterone HIV gp36 Immunoglobulins
PTH HIV gp41 IgA
Influenza A IgE
Influenza B
Leptospira
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Our Capabilities | Polyclonal Antibodies
Inflammation Pregnancy Renal
CRP AFP A2M
B2M
Hormones Inflammatory Cystatin C
HCG A1AT
αHCG
Haematology Metabolism
Immunoglobulins Haptoglobin Ceruloplasmin
IgA Ferritin
IgM Haemoglobin
IgG
Albumin
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Our Capabilities | Recombinant Fab Antibodies
* Detection Ranges are assay dependent and optimised for specific
clinical conditions, therefore may be improved with optimisation
Biomarker Detection Range* Capture Antibody Detection Antibody
HSP60 0.1 - 1200 ng/mL BR100-G2A7 BR100-H4C2
Adiponectin 0.1 - 525 ng/mL BR101-P7E2 BR101-M3H8
Adiponectin 230 - 59118 ng/mL BR101-H2B4 (Competitive ELISA)
Angiopoietin 2 0.001 - 97 ng/mL BR103-P4E8 BR103-V5F2
Big Endothelin 1 0.001 - 1.8 ng/mL BR104-D6A4 BR104-H1A4
Calcitonin 0.006 - 2 ng/mL BR388-G6B1 BR388-D5C4
Cathepsin D 0.03 - 150 ng/mL BR107-F5G2 BR107-K6D3
Eotaxin 0.007 - 2 ng/mL BR108-M7H3 BR108-K2D9
Chondrolectin 0.9 - 21 ng/mL BR111-P8G3 BR111-T6B1
CKBB 0.15 - 33 ng/mL BR112-V6F6 BR112-Z1C4
Proinsulin C-Peptide 0.09 - 38 ng/mL BR143-G5D3 BR143-K7C9
CRP 151 - 231000 ng/mL BR228-D4A3 (Competitive ELISA)
Cystatin C 165 - 9073 ng/mL BR175-G8D9 (Competitive ELISA)
Cystatin C 165 - 9073 ng/mL BR175-H4C8 (Competitive ELISA)
E. histolytica not tested BR116-K9F7 BR116-G3A1
E-selectin 0.05 - 235 ng/mL BR117-K2E7 BR117-H5B6
FABP Intestine 0.65 - 100 ng/mL BR115-F7G7 BR115-G6B9
FABP Liver 0.03 - 90 ng/mL BR106-G5A2 BR106-P9F5
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Our Capabilities | Recombinant Fab Antibodies
* Detection Ranges are assay dependent and optimised for specific
clinical conditions, therefore may be improved with optimisation
Biomarker Detection Range* Capture Antibody Detection Antibody
G. lamblia not tested BR120-P3F2 & BR120-T1G8
Human Fetal Hemoglobin 1.9 - 305 ng/mL BR121-T5H9 BR121-V5A7
Leptin 3.9 - 691 ng/mL BR123-M4D6 BR123-P4G2
MMP7 0.1 - 293 ng/mL BR124-S4E3 BR124-T6G8
MMP9 Active 11 - 183 ng/mL BR125-N5F7 BR125-M6D6
MPO 2 - 1200 ng/mL BR240-N5G6 BR240-D8B4
Neutrophil Elastase 0.008 - 33 ng/mL BR127-H2A4 BR127-G7C2
Free PAPP A 0.3 - 299 ng/mL BR129-M5E3 BR129-F2H4
Pentraxin 3 4.6 - 876 ng/mL BR130-H2C3 BR130-K6D6
PGDS 0.2 - 85 ng/mL BR131-M6H7 BR131-P7F7
PSAP A 0.013 - 123 ng/mL BR132-T5G4 BR132-S6E4
PSAP B 0.3 - 1500 ng/mL BR133-V6B5 BR133-V4D1
RBP 4 350 - 500000 ng/mL BR134-Z7D3 (Competitive ELISA)
S100 Beta 0.04 - 5.6 ng/mL BR332-G4B9 BR332-F5H7
ST2 1.39 - 97 ng/mL BR139-S7B7 BR139-V8D4
ST2 0.08 - 31 ng/mL BR139-T3G5 BR139-V8D4
Tie2 0.8 - 600 ng/mL BR140-Z7A5 BR140-D9D7
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How to Order
Please get in touch to arrange a quote for
any of our products.
You can also order directly via our website
www.bbisolutions.com
USA: 1-800-423-8199
Intl: +44 (0) 2920 747 232
Quote on ordering – NF JAN
BBI Solutions
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BBI Solutions
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