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Fiona NielsenNovember 3 -
2016
Shenzhen, ICG-11
Tweet me @glyn_dk
From bioinformatics
scientist to entrepreneur
The frustrated researcher!
How did this happen?
The long road to resultsRaw reads
Read QC
Variant calling
Analysis-readyreads
Analysis-readyvariants
Variant Annotation Genotype
Refinement Raw Indels
Raw SVs
Raw SNPs
Mapping
External Data
What do you do?
Sequence Read Archive
What do you do?
What do you do?
Yikes
What do you do?
PubMed?
What do you do?
What do you do?
Ask your PI
Write application
Apply for access
Wait…Wait…Wait…Wait…
Access requests can take months
You are not the only one
T. A. van Schaik et alThe need to redefine genomic data sharing: a focus on data
accessibility, Applied & Translational Genomics, 2014
10.1016/j.atg.2014.09.013
Researchers spend months to find and access genomic data, and often choose to not access
data at all
2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Genomes Sequenced~400k genomes produced
And how do you keep up?
More projects launched every day
And how do you keep up?
Data is uploaded to repository
Data is discovered by potential user
Data is accessed by potential user
What IF?You could easily search and
discover data?
You could rank data by relevance?
Registering data was simple to do?
Search would be easy
Collaboration would be simple
You would discover new resources you did not
know existed
https://www.flickr.com/photos/blackzack00/10205948476/
It has taken a while…
DNAdigest was founded in March 2013
Working out what to do
Making data discoverable and shareable
Building through collaboration
DNAdigest organises hackathons/workshops 4 times a year
We founded Repositive
To make genomic data accessible for research
Adrian Alexa CTO & Data Scientist
Fiona NielsenFounder & CEO
A portal to search for data
Interested? Sign up for our beta at repositive.io
To make your data visible
Interested? Sign up for our beta at repositive.io
To collaborate
Interested? Sign up for our beta at repositive.io
Let me show you
But we are not done yet
My researchWorking towards
Open Science
My researchWorking towards
Open Science
• Transparency• Availability• Accessibility• Reusability• Collaboration
Making your contribution should be easy
Supporting best practices: • get credit for making data available• give credit to data producers• Initiate new collaborations
http://en.wikipedia.org/wiki/Karyotype#mediaviewer/File:Spectralkaryotype98-300.jpg
Any questions so far?
https://www.flickr.com/photos/blackzack00/10205948476/
How did I end up here?
• Masters in bioinformatics, Odense, Denmark• Masters project in Nijmegen, CMBI• Continued as Phd student (junior onderzoeker)
with CMBI and Molecular biology
The future is always uncertain
https://www.flickr.com/photos/f4/12652885873
I am just doing what it takes
Team effort
Presenting to the world
Reaching out
ConsultingFundraisingMarketingBrandingPublic EngagementFinancial forecastsPlanningSoftware developmentScienceLong daysLittle financial returnBig satisfaction
Questions? I would love to hear from you , drop me a line at [email protected]
https://www.flickr.com/photos/matthewpaulson/7185380311/
Life as an entrepreneur
Read more at http://repositive.io and http://DNAdigest.org
Thanks for listening!
repositive [ re-poz-i-tiv ], noun; 1. a positive experience of accessing
genomic data repositories
Read more at http://repositive.io and tweet us @repositiveio