A Thriving BioScience Community

“What Successful Technology Regions Eat for Breakfast”

http://www.technologyreview.com/view/516586/crowding-into-biotechs-densest-supercluster/

Silicon Valley biotechnology companies raised $1 billion in 2012, versus $860 million for Massachusetts companies (PWC)

Open Plan - “the kind of place people can come and go and just bat around ideas” J&J

Strengths-Good links between scientists and managers and financiers-Strong regional R&D-Heterogeneous populated of highly educated people-Science Park infrastructure-Anchor Companies-Government support for innovation-Increasing investment in innovation-Attractive region for investors-Qualified support staff-Open Science-Internationally renowned professors or scientists-High mobility – movement of knowledge a, expertise, and jobs-Good place to live

Threats:-Brain drain-Adverse economic or political changes-Few or weak private public partnerships-Lack of government support

Critical Success Factors in Clusters successful clusters = successful companies

A Networked Ecosystem is Critical To Successful Companies…So is leveraging the local heritage and expertise

83% from Biotech or Pharma

7% Academia

Silicon Valley VS Manchester - Liverpool CommuteSan Francisco – San Jose = 48 miles (1 ½ by Train; 1 hour by Car)Liverpool – Manchester = 34 miles (40 minutes by Train; 1 hour by Car)

Across London?

DNA of Silicon ValleyTo adopt a model without consideration

of regional resources and competences risks failure*

...as often happens when regions expect to emulate activities in atypical regions like Silicon Valley or Cambridge, UK (Clarysse, Wright et al. 2005).

*Final report to the Commission for the New Economy, NWDA & AGMA

15 Years!

Continuity of Experience and Talent Difficult to Recover from Loss of Experts

The Impact of a few Connected People…Critical to Success of Companies

“The majority of high technology companies that have shaped the success of Cambridge cluster are connected to a handful of serial entrepreneurs, business angels and venture capitalists”

Studies Show Greater Connectivity Translates to Greater chance of success and increased revenue

MENTOR NETWORKProviding insight & mentoring at various knowledge inflection points along your journey

What state does your business need to be in, look like, do, have in place?Line of Sight Review Board(Critical Friend)

•Payer Groups•Regulatory•Clinical Demand•Patient Usage•Clinical Trial Design•Commercialisation•Licensing•Repositioning•Scientific Assumptions•Funding•M&A•IPO

Life Science Mentor Network

Companies : >160 Companies under BioCity umbrella

Growth on Site: 46% of lease income from companies BioCity directly involved in creating or growing

Survival Rate: 91% survival over 10 years vs 39% UK Life Science failure rate over 3 years

Investment *6.4X and 78% IRR since 2006Returns:

Mitigated Risk: 89% of portfolio companies at or significantly above initial investment value

BioCity’s History of Successful Business Building and Value Creation

*compared to average IRR of 7.05% for 946 early stage US funds over 5 years (Cambridge Associates LLC US Venture Capital Index ® data, 9/2013))

BioHub Growth – One Year On• 17 Physical Companies• 38 Virtual Companies• 7 Corporate Companies• 256 New Staff on Site

BioHub Companies