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What is Non-Hodgkin’s Lymphoma
(NHL)?
Non-Hodgkin lymphoma (NHL) is a term that refers to
the many other types of cancer of the lymphatic
system, which can have different symptoms and
signs, physical findings, and treatments.
What Causes Non-Hodgkin’s Lymphoma ?
EBV and Burkitts lymphoma
Hepatitis C
HTLV1
Helicobacter Pylori causing lymphoma of the stomach.
Chemicals: polychlorinated biphenyls (PCBs),
diphenylhydantoin, dioxin, and phenoxy herbicides.
Medical treatments: like radiation therapy and
chemotherapy
Genetic diseases, like Klinefelter's syndrome, Chédiak-Higashi
syndrome, ataxia telangiectasia syndrome
Autoimmune diseases, like Sjögren’s syndrome, celiac sprue,
rheumatoid arthritis, and systemic lupus erythematosus.
What are the risk factors for Non-
Hodgkin’s Lymphoma?
Being male: Non-Hodgkin’s Lymphoma is more common in
men than in women.
Age: Likelihood of getting Non-Hodgkin’s Lymphoma increases with age.
Viral infections: A viral infection, such as Epstein-Barr virus,
increases the risk of developing NHL.
Environmental exposure: Exposure to agricultural pesticides or
fertilizers, solvents, and other chemicals may increase the risk of developing NHL.
http://www.bmthospitalindia.com/Adult-Non-Hodgkins-Lymphoma.html
What are the Symptoms?
A painless swelling of the lymph nodes in the neck,
underarms, or groin. This is the most common symptom
Fever above 380C (100.4 F)
Drenching Night sweats.
Feeling very tired.
Reddened patches on the skin.
A cough or shortness of breath.
How do we Diagnose Non-
Hodgkin’s Lymphoma?
Biopsy and Histopathology
Complete Blood Count
Bone Marrow Biopsy
PET-CT Scan
Additional Tests: Serum LDH, ECG, Echocardiogram and Lung
Function Tests are done before starting treatment.
How do we treat Non-Hodgkin’s
Lymphoma?
The type of NHL
the stage of NHL
how quickly the NHL is growing (grade) – whether it is slow
growing (indolent) or fast growing (aggressive)
prognostic factors
person's age
person's overall health status and if he has other medical conditions that may interfere with treatment
previous treatment, if any
Treatment plans are designed to meet the unique needs
of each person with lymphoma. Treatment decisions
for non-Hodgkin lymphoma (NHL) are based on:
Treatment options for NHL OTHER
THAN BMT
Chemotherapy
Biological therapy
Radiation therapy
Surgery
Follow-up after completing the treatment
Role of BMT in the treatment of Non-
Hodgkin’s Lymphoma
About 30% patients with advanced disease and 10%
patients with Limited disease relapse.
Once Non-Hodgkin’s Lymphoma relapses, the treatment
is well-defined and as8 follows:
Salvage Chemotherapy
Autologous Peripheral Blood Stem Cell Collection
High Dose Chemotherapy and Autologous BMT
Contact us
Website : http://www.bmthospitalindia.com/Adult-Non-
Hodgkins-Lymphoma.html
Email : [email protected]
Phone : +91-8130000120, 011-43066353
Thank you
Dharamshila Blood and Marrow Stem Cell Transplant Centre
