UK HCPs on the Latest Technologies and Innovations in Type 1 Diabetes

CREATIONPinpoint|HCPSocialMediaStudy|Type1DiabetesEnglish|201501101-20161031| 2

WhatcanwelearnaboutunmetneedsorinterestsamongHCPswhotalkaboutT1Donline?

HowdoHCPsengageonline?

HowdopatientsfeatureintheHCPonlineconversation?

WhatareHCPs’ thoughtsonthelatesttechnologiesandadvancementsinDiabetesaswellastheestablishedtreatments?

Tophealthcareprofessionals

Healthcare professionalonlineprofiles:top-3HCPs

Glossaryofterms

Tableofcontents



Questionsummary



HCPsdiscussingartificialpancreas:HCPswaitedforthereleaseofMedtronic’sMiniMed 670Gwithexcitedanticipation.Duringthereleasetherewasstillanoverallenthusiasmtowardstheproduct,howeverafterrelease,HCPsagreedthatMiniMed 670Gdidnotmeettheirexpectations.

HCPsdiscussinggrowinghumanpancreasinpigs:TherecentdevelopmentsincontroversialstemcellresearchreceivedmixedsentimentwithsomeHCPsintriguedandexcited,whilstothersremainedcautious.ThistopicreceivedasmallershareoftheconversationthanMedtronic.

Diabetesdrugclasses:InthecontextofT1DandT2DDiabetescombined,thebiguanide Metformintookupthelargestshareofvoicewheretopicsincludedweightissuesrelatingtotheproduct.

Discussionofinsulintherapies:TheinsulintherapyLotusmadeupalmosthalfoftheallinsulintherapyconversation.Itwasmostlydiscussedinrelationto otherinsulinproducts.

18%

13%

5%

5%

4% 3%

45%

3% 2% 2%

FreeStyle(Libre)

Medtronic(MiniMed)

OmniPod

Dexcom(G5)

Viacyte(VC-01)

Animas

Artificalpancreas*

Piggrownpancreas

Contactlens

Skinpatch

WhattechnologiesareHCPsdiscussingwithintheDiabetesspace?

CREATIONPinpoint|HCPSocialMediaStudy|Type1DiabetesEnglish|201501101-20161031|

Observations:

Whendiscussingmedicaladvancements,HCPsoftenspeakofthedevelopmentsintheartificialpancreaswithoutspecificallynamingtheproduct.

5

n=483

*withoutreferencetoaspecificartificialpancreas

0

5

10

15

20

25

ArtificialPancreas Medtronic/MiniMed

HCPsdiscussingtheartificialpancreas


Observations:

TherewasmuchexcitementtowardsMedtronic's670Gthroughout2016especiallyforthosewithT1D.

6

Pre-launch

Observations:

Thelaunchwasmetwithnonegativesentiment.HCPseitherrelayedtheannouncementthattheFDAhadapprovedtheartificialpancreasorshowedenthusiasmfortheproduct’spotential.

Observations:

JustonemonthafteritwaslaunchedsomeHCPswerenothappywiththeresult,claimingitwasaletdownandadisappointment.

Launch Post-launch

HCPsdiscussinggrowinghumanpancreasinpigs


“- AaronDehgham,MedicalStudent

10June2016

Fascinating! Pigs may once again play

a pivotal role in Diabetes

“Insight:Volumeofcontentwasmuchlowerdiscussionsurroundingthegrowingofhumanpancreasesinpigs.HoweverthetopicdividedHCPs:somebelievingitisanothergreatscientificadvancementwhileothersaremoresceptical.

“- CarrieRuxton,Dietician

6June2016

The NHS already used pig insulin to

treat human Diabetes

““

- KathrynFry,ResearchNurse6June2016

Not entirely sure about having a human

pancreas that had been grown in a pig,

transplanted into me

“ “- AshPaul,MedicalDirector

6June2016

Human pancreas grown in pig trial that

could lead to harvesting of donor

organs

“1 HCPshare

2 HCPshares

7

Insulintherapies


1%

12%

46%

29%

12%

Apidra Humalog Lantus Levemir Novolorapid

n=187

TopicsbeingdiscussedrelatingtoLantusandDiabetes

Observations:Withintheonlineconversationrelatingtoinsulintherapies,Lantusreceivesthelargestshareofvoice.WithregardstotheLantusconversation,HCPswereprimarilycomparingitwithotherinsulintherapies.

Never

DiabetesDrugClassshareofmention


1% <1%

63%

14%

9%

12%

1%

AlphaGlucosidaseInhibitors AmylinAnaloguesBiguanide DPP-4inhibitorsGLP-1agonists SGLT2inhibitorsSulphonylureas

n=938

Topicsbeingdiscussedrelatingtobiguanides andDiabetes

Observations:Biguanides dominatetheonlineHCPconversationrelatingtodrugsintheDiabetesspace.Metforministheonlybiguanideavailableonthemarket.Thediscussionsurroundingmetforminseenabovewastodowiththebenefitsofthedrugandhowithelpspertainingtoweight.

10

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