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Nutrition, Exercise and Health: What’s New?
Thursday 12 March@weahsn
Welcome & Housekeeping
Steven WalkerDirector GeneralCampden BRI
Collaborate 2 Innovate
Lars SundstromDirector of Enterprise and TranslationWest of England Academic Health Science Network
15 Regional AHSNs
Funded by NHS England
5 Year License,
Just over 1 year old
Budget £2.8M and size 2.4M population
WEAHSN Member Organisations
5 Community
Health Services
Providers
3 Universities
2 Mental Health Trusts
6 Acute Trusts
1 Ambulance
Trust
7 Clinical
Commissioning Groups
AHSNs
• Building a culture of collaboration and partnerships
• Speeding up adoption of innovation into practice• Creating wealth through co-development testing and
early evaluation and spread of new products and services
Enterprise & TranslationDeveloping new approaches to linking university and industry sectors with the NHS to adopt new solutions for the benefit of our patients
Patient SafetyImproving patient safety to reduce incident and mortality rates.
Quality ImprovementSupporting local health and social care staff to spread good practice across the West of England AHSN region.
Allowing clinicians to share patient data (with their consent) across hospitals, GP practices, communities and social care. This will contribute to better patient outcome
Connecting Data for Patient Benefit
AHSN Workstreams
9BUSINESS PLAN
Six priorities – developed with our stakeholders
1 Be challenge led•identify areas of opportunity,
•challenge the community to respond
•build teams around delivering solutions.
2 Regional growth•work with local industry (SME)
•help access appropriate NHS resources
•co-create solutions
3 Partner with Industry•articulate areas of strength
•align objectives
•build partnerships
4 Unblock down stream value•harmonise procurement
•streamline adoption
•empower local champions
5 Change culture •responsive towards industry need
•entrepreneurial
•understanding each others needs
6 Adopt and spread•spread adoption locally
•network with other AHSNs
•national/international
Challenge led approach
AHSN Challenges
Highlights 2014-2015
• 335 companies contacted us last year 121 businesses assisted, 80 full business assists
• 4 health care challenges £6M Invested into 17 SME £1.5M invested with corporates• Communication channels Industry newsletter – over 300 subscribers Funding finder – over 150 subscribers 17 Companies on our new video-channel (Oct)• Industry partnering and networking events 275 introductions made• Enterprise training for around100 delegate 20 new health entrepreneurs on 3 day boot camps (April) Dragons den style investor panel
In progress 2014-2015
• SBRI Spring Competition (May)
• Citizen centric Innovation programmes– Self Help tools for chronic conditions (mHealth - Diabetes)
– User led design challenge – Citizen centric tools and data collaboration
• Health Innovation programme – Research-4-Health– Health Innovation fellowships– Enterprise fellowships
Get in touch with us
• Visit out website www.weahsn.net/our-work/wealth-creation
• Email us [email protected]
• Call us 0117 900 2157
Food and Innovation Health Service
Emma HanbyProduct Innovation LeadCampden BRI
Overview/contents
• Trends in NPD
• What we offer to support NPD
• Our facilities
• Examples of our work
What drives product innovation?
• Consumers
• Media
• Government
Global
• Population 7.2 Billion and growing – By the time we finish this presentation, 5200
babies will have been born around the world, with a life expectancy averaging 68 years.
• Consumers – increasingly curious about what’s in their food,
where it came from, how it was grown, and how the package that covered it is returned into the environment
Time precious
Cost/value for money
Consumer shopping decision 1995 vs 2013
Data from Kantar World Panel
Idea generation
• Company driven
• Some ideas are more planned than others
• Multi disciplinary team to help with idea generation
Feasibility or concept testing
• Exploratory qualitative consumer research
• Quantitative consumer research
• Ingredient functionality
• Regulatory affairs
• Technology scouting
• Packaging
• Concept samples
Product development
• Bench scale (<5L)
• Pilot scale (50-100L)
• In pack and in line processing facilities
Facilities
Testing (and tasting)
• Storage (-18°C - +40°C)
• Quality changes
• Shelf life
• Sensory discrimination tests
• Sensory descriptive tests
Some examples
Sweeteners and fat replacers for reducing calorie content of food and beverages
• An internal project funded as part of members subscription
• 3 years
• Steered by a member interest group
• To investigate approaches to reduce sugar content of a variety of products
Work conducted
• Literature review
• Sugar reduction in beverages– Steviol glycosides– Monk fruit
• To simultaneously tackle sugar and fat reduction in bakery products– Sugar & fat reduction in cakes– Sugar & fat reduction in filled biscuits
Outputs
• Research Summary Sheets
• Research & Development reports
• Presentation to MIGs
• Assistance with enquiries
• Project website
Food & Health Innovation Service
£4.4m, five-year project funded by Scottish Enterprise that will help Scottish food and drink companies tap into a growing market for food and health related
products which is worth £20bn in the UK and over £300bn globally
Our AimFHIS aims to stimulate Scottish food and drink producers to develop and market products for the ‘health’ market.
We intend to support approximately 500 Scottish food and drink companies with growth potential over 5 years who are currently in or are seeking to enter the food and health market with innovation projects of varying sizes.
Holistic Approach to Company Support
Marketing
Technical
Science
Market & Legislative SupportHelp companies understand the specific market opportunities in food and health which are relevant to their business and how they can address these opportunities
•Market research support•What’s Hot in Health•Bespoke marketing and legislative assistance•Access to network of marketing and legislative experts where required•Regular FHIS eZines
Technical/Scientific Support
•Intensive Support from Project Partners to articulate, scope, and plan projects•Leverages world class B2B and academic support from Campden BRI, Rowett, Interface and associated networks•Scoping of both single company and multi partner projects
Provide technology solutions for companies looking to develop new food and health related products through:
Visit from FHIS Advisor
Innovation Action Plan
Marketing Support Options Identification of Technical Requirements & Approaches
FHIS Expert Health Marketing Advice
Collaborative Project with FIA
A typical example:
Case studies
www.foodhealthinnovation.com
What’s Hot InHealth?
NPD INSIGHTS
NUTRITIONALSUPPORT
NPD is a complex process
• It requires a knowledge of– Ingredients
– Processing– Packaging– Regulations– Consumer preferences
• We have a multi disciplinary team
Campden BRI‘The partner of choice for the development and application of technical knowledge and commercially relevant solutions
for the food and drink supply chain’
www.campdenbri.co.uk
no. 1207
no. 1079
Sport, Exercise and Wellbeing Evidence based Interventions in the Community
Diane CroneProfessor of Exercise Science University of Gloucestershire
#InnovateNutrition
Sport, Exercise and Wellbeing
• Physical activity and health promotion– Health referral pathways
– Hard to reach groups at risk for Metabolic Syndrome
– Sedentary behaviour
– Coronary vascular disease rehabilitation
• Athlete Wellbeing and Sports Performance – Injury prevention in youth sport
– Alteration of nutritional intake prior to exercise influences energy expenditure
• Clinical Health and Wellbeing – Aetiology of cardiovascular disease
Health Referral Pathways
• Primary focus:– Uptake, adherence and completion of physical
activity programmes and socio-demographic characteristics
– Behaviour change and health outcomes
• Including: – Exercise referral programme (primary care)
– Physical activity pathway (adults and children, community based)
– Arts for health
Contact: Prof Diane Crone [email protected]
Hard to Reach Groups at Risk for Metabolic Syndrome
• Primary focus: – Promote healthy lifestyle and
positive behaviour change for hard to reach groups (sports fans).
• Including: – Health and lifestyle programme
includes health education and physical activity
Contact: Dr Elizabeth Loughren [email protected]
http://www.fans4life.com/
Sedentary People
• Primary focus:– Active Together – GCC Grant scheme to
empower communities to encourage more sport and physical activity across the county
• Including:– Social Return on Investment (SROI)
evaluation to;• understand and value the changes that occur as a
consequence of projects implemented;
• develop a blueprint for the delivery and evaluation of similar future programmes.
Contact: Dr Colin Baker [email protected]
Exercise Rehabilitation Programmes
• Primary focus:
– Exercise promotion for patients with
Coronary Heart and Vascular Disease
• Overall aim:– Increase access to, and effectiveness of,
exercise as treatment for chronic illness
– Improve CV system efficiency and QoL,
– Reduce risk factors, symptom presentation and mortality risk
Contact: Michael McCluskey [email protected]
Injury Prevention in Youth Sport
• Primary focus:– To identify injury risk factors, develop appropriate
injury screening and prevention programmes for youth participants.
• Overall aim:– To reduce the physical and mental health burden
of injury incidence in youth sport and exercise
• Current sports include: – football, rugby, basketball and ice hockey
Contact: Professor Mark De Ste Croix
Alteration of Nutritional Intake Prior to Exercise Influences Energy Expenditure
• Primary focus: – Caffeine ingestion prior to exercise increases subsequent energy
expenditure (EE) & lowers perception of effort.
– Benefits of increased EE to those seeking weight loss,
– Increase adherence to exercise programmes as perceived “easier”.
• Possible future research/collaboration:– Could increased EE translate to increased weight loss long-term?
– Potential increase in adherence to intervention programme
Contact: Dr Matt Cole
Monday, March 16, 2015 58
Aetiology of Cardiovascular Disease
• Primary focus:
– Developing new non-invasive tests to determine early markers of CVD in ‘at risk’ populations
• Interests include: – Determining how exercise can
moderate the physiological effects of acute mental stress and provide an enhanced level of cardio-protection
Contact: Dr Simon Fryer [email protected]
60
Introduction to the NIHR Biomedical Research Unit
Andy NessDirector & Professor of EpidemiologyNutrition Biomedical Research Unit
@weahsn#InnovateNutrition
The NIHR Biomedical Research Unit at the University Hospitals Bristol
NHS Foundation Trust and the University of Bristol in Nutrition, Diet
and Lifestyle
Bristol Nutrition BRU
• Professor of Epidemiology and Head of Lifecourse Epidemiology and Population Oral Health Group at University of Bristol
• Director of the Biomedical Research Unit in Nutrition, Diet and Lifestyle at University Hospitals Bristol NHS Foundation Trust and the University of Bristol
• NIHR Senior Investigator
BRU Executive team
Bristol Nutrition BRU
• Ashley Cooper• Julian Hamilton-Shield• Vanessa Marshall• Richard Martin• Andy Ness
What are Biomedical Research Units?
• Experimental medicine• NHS Trust and University partnership• Programmes in a defined area• 20 Units in UK
Bristol Nutrition BRU
Bristol nutrition BRU vision
“Translate causal associations in nutrition drawn from population and clinical studies into interventions for people with conditions related to (or compromised by) poor or sub-optimal nutrition”
Bristol Nutrition BRU
Bristol Nutrition BRU
• Opened 1st April 2012• 5 year award of £4.5 million• Core theme
– Methodology– Translation and transfer of ideas
• Four specific themes– Pre and post surgical feeding– Nutrition in men with prostate cancer– Optimising nutrition in children with chronic disease– Sedentary behaviour in people with diabetes
Bristol Nutrition BRU
Structure
Bristol Nutrition BRU
Supporting careers in science
• Charter for Women in Science• Silver Award April 2013 • SWAN champion in place• BRU staff survey completed
Bristol Nutrition BRU
Dr Andrea WaylenSWAN champion
MethodologyChris Penfold Statistician
Rachel Perry Systematic Reviewer
Aidan Searle Qualitative Researcher
Eileen Sutton Qualitative Researcher
Stu Toms Database Manager
Bristol Nutrition BRU
Management/Admin
Andy Ness Director
Vanessa Marshall Manager
Shirley Jenkins Management Assistant
Katie Berryman Trials co-ordinator
Rhona Beynon Intern
Bristol Nutrition BRU
Perioperative NutritionCharlotte Atkinson Theme Lead
Georgia Herbert Research Assistant
Vaneesha Short PhD Student
Caroline Taylor Research Assistant
Elizabeth Arthurs MD Student
Bristol Nutrition BRU
Systematic reviews
• Early enteral nutrition– No benefit in keeping people nil by mouth – Possible benefit on complications and length
of hospital stay
• Chewing gum and postoperative recovery– 81 trials, 9072 study participants– Some evidence for a benefit of chewing gum
on time to first bowel movement and flatus
Qualitative studies
Patient views of perioperative nutrition
– To describe perioperative nutrition experiences and identify barriers/facilitators to feeding
– Semi-structured interviews with people who have undergone colorectal surgery (n=16)
– Information provision is poor, range of food available
Chewing gum randomised trial
• Trial outcomeo No effect on length of stay or measures of bowel functiono Possible reduced risk of vomiting post-operatively
• Observational analyseso Predictors of when people start eatingo Early feeding as a predictor of outcome(s)
Sedentary
Ashley Cooper Theme Lead
Catherine Falconer
Research Associate
Laura Brocklebank PhD Student
Bristol Nutrition BRU
Describing sedentary behaviour
• Observational study of people with newly diagnosed type 2 diabetes– Sedentary time and metabolic outcomes– Dietary behaviours and sedentary time– Contribution of time outdoors and active travel to activity
Bristol Nutrition BRU
Bristol Nutrition BRU
Jour
ney
1 Journey 2
Journey 3
Interrupting sedentary behaviour
• Intervention in middle aged adults• Randomised three-treatment crossover trial
o Uninterrupted sitting o Sitting interrupted every 20 mins by 2 mins of walking o Sitting interrupted every 20 mins by 2 mins of standing
• Outcome: postprandial interstitial glucose concentration
Bristol Nutrition BRU
Prostate Cancer
Richard Martin Theme Lead
Lucy Hackshaw-McGeagh
Research Associate
Vanessa Er PhD Student
Kalina Biernacka Research Technician
Ola Frankow Research Technician
Bristol Nutrition BRU
Childhood Disorders
Julian Hamilton-Shield
Theme Lead
Laura Birch Research Dietician
Georgina Williams
Research Fellow and Clinical PhD Student
Elanor Hinton Research Associate
Bristol Nutrition BRU
TRAINING PORTFOLIO
Students & placements
NHS and University training
NIHR training
BRU internal training & staff review
BRU open training
Bristol Nutrition BRU
Dr Charlotte AtkinsonTraining Lead
Training
Patient and public involvement
Bristol Nutrition BRU
Dr Eileen SuttonPPI Lead
Public Engagement
• Engagement policy • Supporting events• Specific projects
Bristol Nutrition BRU
Clinical trials day - May 2014
Ms Rachel PerryPublic engagement lead
Green Man festival - August 2014
Website
Bristol Nutrition BRU
www.bristolnutritionbru.org.uk
Projects by theme
Bristol Nutrition BRU
Recruitment by theme
Bristol Nutrition BRU
Collaborations
Bristol Nutrition BRU
AberdeenAberdeen
LeedsLeeds
LeicesterLeicester
CambridgeCambridge
SouthamptonSouthampton
PlymouthPlymouth
CorkCork
BristolBristol
Manchester
Manchester
BirminghamBirmingham
BournemouthBournemouth
TauntonTaunton
BelfastBelfast
DurhamDurham
Summary
• Open for three years• Staff, reporting and policies all in place• 66 projects open• 744 participants recruited
Bristol Nutrition BRU
Any questions?
Bristol Nutrition BRU
Optimising nutrition to improve the health of children with chronic disorders
Vanessa MarshallManager Bristol Nutrition Biomedical Research Unit
@weahsn#InnovateNutrition
Spectrum of studies
Bristol Nutrition BRU
Feasibility studiesDevice testing
Functional studiesEpidemiology studies
Qualitative studies
Randomised trials
n ≥20
Cohort
Eating behaviour
Bristol Nutrition BRU
Bristol Nutrition BRU
FTO gene rs9939609 obesity-risk allele
Bristol Nutrition BRU
Calorie content and food types vs genotype
Crowd-sourcing of dietary data for nutritional assessment
Industry
Bristol Nutrition BRU
Renewal• Integrate with
– MRC IEU• Eating behaviours• Outcomes (genetics, epigenetics, metabolomics)
– Nutrition and Behaviour Unit• Eating behaviours in the well and unwell
– Exercise, Nutrition and Health Sciences• Activity and dietary interventions to improve health
– Asthma– Obesity– Diabetes– Other chronic conditions
– Increased collaboration with industrial partners
Bristol Nutrition BRU
Introducing the Nutrition and Behaviour Unit
Jeff BrunstromSchool of Experimental PsychologyUniversity of Bristol
@weahsn#InnovateNutrition
1. Why can’t I resist?
2. How is meal size controlled?
Understanding decisions about portion size: The key to acceptable foods that reduce energy intake?
Expected satiety and expected satiation
Standard Comparison
Match the food on the right to be as filling as the food on the left
Translation
3. Why does eating rate influence appetite?
“Understanding eating topography: The key to reducing energy intake in humans?”
Horace Fletcher (1849–1919)
4. Behaviour change by stealth – can we nudge towards healthier dietary behaviour?
Nudge150: Combining small changes to foods to achieve a sustained decrease in energy intake
• The difficulty in eating less lies in feeling deprived of something that is rewarding (i.e. enjoyed), rather than not feeling full
• Our objective therefore is to find ways to maintain the reward value of smaller portions of food
5. Why do I choose that food?
WP5 Deconstructing food choice: a role for sensory, nutrient, and satiety reward
Best-fitting BETA values for across different regressors.
6. Dietary complexity
Does flavour-nutrient inconsistency compromise energy regulation in humans?
Collaboration with industry partners
Nutrition and Behaviour Unit,School of Experimental Psychology,
University of Bristol, 12a Priory Road,
Bristol, BS8 1TU, UK.
Email: [email protected]
Introduction to Gfirst
David OwenChief Executive OfficerGfirst (Gloucestershire Local Enterprise Partnership)
@weahsn#InnovateNutrition
David OwenChief Executive
www.gfirstlep.com@ceogfirst
The Economy of Gloucestershire
ExportStart Up
High TechHigh Skills
Local EnterprisePartnerships?
How can we help?
GL AmbassadorsSector GroupTheGrowthHub.biz
David OwenChief Executive
www.gfirstlep.com@ceogfirst
The Economy of Gloucestershire
Q & A Panel Session
#InnovateNutrition
@weahsn
Company Introductions
#InnovateNutrition
@weahsn
Institute of Bio-Sensing Technology- biology for sensors and sensors for biology-
Prof Richard Luxton
biology for sensors and sensors for biology
Aims of IBST
• Instigate academic and industrial partnerships to develop multi-disciplinary research projects to create and exploit new technology.
• Act as a hub for knowledge exchange activities across diverse disciplines for the benefit of the business and scientific communities.
• Raise the profile of UK bio-sensing research and
development and ensure that UK remains a world leader in the field.
biology for sensors and sensors for biology
Magnetic detection Volatile analysis
Bioluminescence
Instrument development
Technologies at UWE
Hyperspectral Imaging
Electrochemistry Impedance spectroscopy
Cell technologiesBiomarker discovery
Food safety
• Pesticide residues
• Toxins – mycotoxins (e.g. Ergot)
• Antibiotic residues• Infectious agents
– Bacteria– Virus– Worms (Helminths)– Fungi
biology for sensors and sensors for biology
http://www.biosensingtech.co.uk/
Thank you for your attention.
Are there any questions?
biology for sensors and sensors for biology
Ann Malone
Health Evolution LtdA not-for-profit Company Taking healthy cooking, nutrition and
lifestyle education and information
Into workplaces, schools and the heart of communities
Project Development
•Location – Health Statistics•Aims and Objectives•Outcomes
What do we do?• Run 4 classes over 6 week period• Provide optional health checks• Food• Cooking Demonstrations and Tasting• Activity• Mind
Whole Wellness Picture
Core Concepts• Maintenance of even Blood Sugar• Only as healthy as your gut• Healthier food choices and cooking• Get moving• Manage Life Load• Whole Picture – Food, Body and Mind• Have fun!
Who’s Involved• Local Community• Local Authority, Agencies, Support Groups• Work placement Students• Volunteers• GP Surgeries, CCGs
Sustainability• Taster Sessions• Group Volunteer • Buddy Up• Website www.healthy-directions.co.uk• Signpost to local agencies/support
Measuring Success• Registration Forms• Health Checks – Personal Record• Personal Action Plan• Personal health and food concerns answered• End Course Evaluation Forms• Recommendations
Success Stories• Client A “Every one should have access to this
course”
• Client B “Very informative, easy to understand and put into action”
• Health Evolution – second grant
An introduction to 500 More and Walking Safari
500More 14403/16/15
Mobile Apps for Health and Wellbeing
03/16/15 500More 145
Understand
what people want
Deliver Compelli
ng Experien
ces
Drive Insight from Data
Deliver Robust
Solutions
A Public Health Example – Encouraging Walking
03/16/15 500More 146
Because it could help you to be healthier in the future….Walk more steps today…..
The Traditional Pitch
+ it will help you to be healthier in the
future….Walk more steps today..
A Better Model – Build more Value into a Step!
Because each step matters
• To play
• To give
Changing behaviours requires smarter approaches to driving motivation….
Walking Safari is a app that combines Walking and Giving
03/16/15 500More 147
The ‘buzz’ of achieving rewards and making donations encourages players to keep going
Players record profile data and personalise their experience
Players showcase their achievements, seeking approval and validation from their peers
Players walk, the phone acts as pedometer
Players take on personalised ‘micro-challenges’ which build into ‘meta-challenges’
The use of personal and team challenges inspires people to walk more and spurs them on to keep trying
*
* Planned Functionality
Organisations can match fund employee giving based on the number of steps walked*
Walk to Give….
03/16/15 500More 148
2 Month Group Challenge
Micro Challe
nge
Micro Challe
nge
Micro Challe
nge
Micro Challe
nge
Daily/Weekly
Challenges
Daily/Weekly
Challenges
Daily/Weekly
Challenges
Daily/Weekly
Challenges
Monthly Challenge
Different kinds of experiences for challenges of different durations allows game evolution at multiple levels
£/10,000 steps Pat
h
Span
Dot
Micro Challe
nge
500 More, the Story So Far
Some organisations we’ve spoken to…,
Corporate Wellbeing Public Health Clinical Use
500 More is….
e. [email protected]. www.500more.comt. @500moreuk
• Greg Smart: CEO
• Digital Health Consultant 25 years in IT industry
• Clients include startups, Oxford University, various hospitals and Bupa
• Andy Wilkins: Head of Consulting
• Customer Experience consultant
• Clients include Virgin Atlantic, Barclays, O2, BT, Avis, Bupa and NHS
• David Gibson: CTO
• Mobile software and game developer
• Clients include London Air Ambulance, Advanced Health & Care, PwC, Nationwide and Audi.
Bryan HanleySpecialist – Food Sector
Innovate UK and the KTN
Innovate UK – new name for the Technology Strategy
Board. Developing innovation & funding at the strategic level
KTN – “people on the ground” helping companies to network & apply for funding; funded by
Innovate UK
What we do
KTNThe UK’s Innovation Network
The KTN is the UK’s innovation network. It brings together businesses, entrepreneurs, academics and funders to develop new products, processes and services
We help business to grow the economy and improve people’s lives by capturing maximum value from innovative ideas, scientific research and creativity
KTNEnabling Collaboration
Strategic Interdisciplinary Entrepreneurial CommercialConnecting people who wouldn’t usually meet to
solve innovation challenges
Bringing together businesses and researchers from different sectors
Linking people with new ideas and technologies to partners and customers Introducing innovators to
public and private funders and investors
KTNCommunities, Projects & Business Programmes
Focus is on bringing together groups of those that would not normally meet
Sustainability & Resource Efficiency, H2020, Access to Funding & Finance, Design …
Sustainability &
Resource Efficiency
Innovate UK AgriFood Strategy• Next strategy for 2015 – 2020
Precompetitive Vision for UK Food and Drink Industries
— Request by the KTN, on behalf of industry, to the UK government for £100M pre-competitive funding
— Underpinning Research Needs: — A fundamental understanding of food structure— A resilient food supply— Knowledge based understanding of gut physiology and
microbiology, the interaction between the two and how these might be optimised
— An understanding of psychobiological parameters such as taste, appetite and satiety
— A real understanding of the process of food choice
Redesigning the food supply chain: choosing and producing healthy, nutritious and sustainable food
— The UK Food and Drink Landscape can be complex and difficult to navigate
— The Food team have created three food maps to give topline information about the organisations working in the Food and Drink Landscape
KTN Food and Drink Maps
— UK Food and Drink Landscape— This map outlines the different organisations involved in the UK Food
and Drink Industry.
— UK Food Capability Landscape— This map outlines different food research areas and which research
organisations are active in this area.
— UK Industry Technical Capability Landscape— This map contains information about the UK food industry technology
demonstration centres which are available for use by stakeholders.
KTN Food and Drink Maps
— Keep in contact— Contact us at an early stage to discuss potential
projects, partners and funding— Register with us on _connect
connect.innovateuk.org/web/biosciencesktn— Suggest events/activity you’d like to see happening— Keep us aware of changes and developments
Getting the most from the KTN
KTNThe Future. Faster.
THANK YOU
