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Ebola Outbreak Lessons learnt! Prof Shaheen Mehtar Chair ICAN, UIPC, Stellenbosch Uni, CT

Lessons learnt from ebola

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Shaheen Methar's fantastic talk on Ebola at ICAN 2014 in Harare, Zimbabwe. Thanks for letting me share her talk)

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Page 1: Lessons learnt from ebola

Ebola  Outbreak  Lessons  learnt!  

 

Prof  Shaheen  Mehtar  Chair  ICAN,    

UIPC,  Stellenbosch  Uni,  CT  

Page 2: Lessons learnt from ebola

In  the  beginning…  

•  In  2012  and  2013  there  was  an  outbreak  of  Ebola  amongst  the  great  apes  in  the  DRC  and  surrounding  areas  which  largely  went  unnoLced  (  over  5000  apes  died)  

•  On  13  Dec  2013  a  2  year  old  child  was  diagnosed  with  Ebola  in  Guinea-­‐  contact  with  infected  bush  meat!)  

•  That  was  the  epicentre  of  the  outbreak  which  also  largely  went  unnoLced  

Page 3: Lessons learnt from ebola

Spread  like  wildfire.  

Page 4: Lessons learnt from ebola

Low  resource  countries  

•  High  supersLLous  beliefs  •  Great  dependence  and  reverence  for  tradiLonal  heads  and  healers  

•  SLgma  associated  with  lack  of  knowledge  

•  No  tradiLonal  heads  of  tribes  or  healers  were  include  in  the  HC  program  

•  Inadequate  infrastructure-­‐  highly  burdened  

Page 5: Lessons learnt from ebola

There  was  total  panic  &  confusion!  

Page 6: Lessons learnt from ebola

Lesson  No  1:  involve  the  community  

•  Locate  the  heads  of  community,  tribal,  urban,  or  government  structures  

•  Respect  the  culture  and  tradiLon  

•  Explain  and  educate-­‐    •  They  will  understand    •  You  will  get  their  trust.  •  They  will  influence  the  community  

Locals  talking  and  discussion  EVD  

Page 7: Lessons learnt from ebola

Lesson  2:  A  weak  healthcare  system  

2012   Guinea     Liberia   Sierra    Leone  

Total  populaLon  (millions)   11.45   4.19   6  

<  5y  mort  /  1  000  live  births   101   75   182  

 Mort  15  &  60  yr  m/f  (/1000  pop)  

306/277              71%  (ID)   282/246   444/426  

Total  expenditure  on  health  per  capita  ($)    %  of  GDP  

67    (6.3)  

102  (15.5)  

205    (15.1)  

Doctors  /10  000  pop  (regional  average  4.6)   0.03   0.1  

 0.2  

Nurses-­‐  /10  000  pop  (regional  average  12.6)   0.04   2.7  

 1.7  

Nigeria    

169  

124  

371/346  

161    (6.1)  

4.1  

16.1  

Page 8: Lessons learnt from ebola

Healthcare  structures  for  EVD  Strengthen  the  communicaLon  for  improved  contact  tracing  

Page 9: Lessons learnt from ebola

Lesson  3:  weak    surveillance  system  

Page 10: Lessons learnt from ebola

In  Africa  from  Dec  2013  

DRC-­‐  separate  outbreak  

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30  Sept,  first  case  outside  Africa!  

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Funding  started  coming  –  in  late  August!  

•  NOW  IS  A  POLITICAL  ISSUE  •  American  lives  are  at  stake!  

– Money-­‐  coming  in!  –  Deployment  of  troops  –  Healthcare  workers  – Mobile  laboratories  – Mobilizing  global  resources  

•  Contain  Ebola  in  West  Africa  to  stop  it  spreading  to  USA  &  Europe!!  

Need  5000  more  HCWs!  

Page 13: Lessons learnt from ebola

Lesson  4:  The  leadership  gap    

•  The  flaws  in  the  internaLonal  response    was  slow,  uncoordinated  and  not  parLcularly  strong,  most  global  health  experts  agree.    

•  By  the  Lme  the  World  Health  OrganizaLon  officially  called  it  a  public  health  emergency  in  August,  the  outbreak  was  already  exploding  in  Liberia,  Sierra  Leone  and  Guinea.  

•  MSF  was  in  West  Africa  for  malaria  and  took  over  Ebola-­‐  insufficiently  prepared!      hjp://www.poliLco.com/story/2014/09/the-­‐ebola-­‐leadership-­‐gap-­‐111405.html#ixzz3HQKTR1a6    hjp://www.poliLco.com/story/2014/09/the-­‐ebola-­‐leadership-­‐gap-­‐111405.html#ixzz3HQKHAPdB  

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Outbreak  rages  on!  

•  Ebola  could  infect  1.4  million  in  Liberia  and  Sierra  Leone  by  end  of  January  2015  (PredicLve  model  by  CDC)  

•  WHO  budget  cut  in  past  5  years  by  $16  billion!    •  Total  budget  today  is  only  $4  billion!  

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And  Today?  

Page 16: Lessons learnt from ebola

Lesson  5:  IniLally  untrained  HCW  sent  to  work  with  EVD    

Panic  response  from  most  organizaLons!!  Healthcare  workers  affected  •  A  total  of  450  health-­‐care  workers  (HCWs)  are  known  to  have  been  infected  with  EVD  up  to  the  end  of  23  October  2014:    

•  80  in  Guinea;  228  in  Liberia;  11  in  Nigeria;  127  in  Sierra  Leone;  one  in  Spain;  and  three  in  the  United  States  of  America.    

•  A  total  of  244  HCWs  have  died.  

Page 17: Lessons learnt from ebola

EVD  exposure  risk  in  HCW  

JID  1999;179  (Suppl  1)  Ebola  Serologic  Survey  of  Health  Workers  

Contact  areas  in  the  workplace   Number   %  Total  number  interviewed   279  In  paLent  room   233   84  Feeding  &  talking   145   52  Examining  paLent   43   15  Lab  handling  blood   17   6  Taking  blood   31   13  Washed  paLent   10   4  Washed  paLent  clothes   7   3  Washed  cadaver   20   7  Contact  at  home  &  HCF   30  Contact  at  home  only   3  

Page 18: Lessons learnt from ebola

HCW  contact  with  EVD  Category   Number   %age  A_ack  rate   37/  429   9%  Physicians   4/13   31%  Nurses   22/212   10%  Technicians   7/62   11%  Others   4/111   4%  

Type  of  contact   Number   %age  

Direct   204   73%  Indirect   3   33%  Unlikely   63   64%  Unknown   9   56%  

Page 19: Lessons learnt from ebola

How  infecLous  is  Ebola?  

Page 20: Lessons learnt from ebola

Lesson  6:  First  IPC  principles  FIRST!!  

•  CONTACT  PRECAUTIONS!  

•  Which  means  –  IsolaLon    –  Hand  hygiene  –  Gloves  –  Splash  protecLon  for  mucous  membranes  

–  ProtecLon  of  skin  

•  AdministraLve  controls  –  Triage  –  Test    –  Separate  suspected  and  confirmed  cases  

•  Environmental  controls  –  Clean  and  dry  –  VenLlaLon  

•  PPE    

Page 21: Lessons learnt from ebola

Dressing  up  for  Ebola  

Page 22: Lessons learnt from ebola

Differences  in  PPE  –both  effecLve?  

Page 23: Lessons learnt from ebola

Difference  in  isolaLon  faciliLes-­‐  2014  

Rudimentary:  Plasac  buckets  for  disinfectant  or  even  possibly  vomit  from  paaents  stand  in  front  of  simple  paraaons  put  up  to  make  cubicles  for  the  ever-­‐increasing  number  of  paaents  

Isolator  used  to  treat  VHF  at  the  RFH  

Page 24: Lessons learnt from ebola

Challenges  with  IsolaLon  areas  

•  Shortage  of  staff-­‐  so  stay  on  duty  longer  than  the  recommended  70  min  

•  Overcrowding-­‐  heavy  contact  within  the  faciliLes  

•  NO  venalaaon-­‐  ???  •  HCW  get  over  heated  in  Tyvek  coverall  suits-­‐  39o  C  inside.  

•  Loss  of  funcLon  by  HCWs  and  make  mistakes  

Page 25: Lessons learnt from ebola

A  lot  of  chlorine  spraying!  

•  Try  to  keep  the  environment  clean  and  dry!  

Page 26: Lessons learnt from ebola

WHO  Interim  IPC  guidance  for  EVD  

•  General  guidelines  for  containment  of  Ebola  

•  Produced  in  10  days!  •  Widely  circulated  •  Adapted  by  ICAN      

Page 27: Lessons learnt from ebola

OTHER  WHO  GUIDELINES  (ICAN  involved)  

Specific:  Personal  Protecave  Equipment  •  What  is  recommended?  •  How  to  use  it?  •  Discussion  on  the  use  of  

chlorine  

Specific:  Healthcare  Waste  Management  •  What  is  recommended?  •  What  should  not  be  done?  •  ApplicaLon  of  these  GL  in  

various  countries  

Page 28: Lessons learnt from ebola

PPE  when  handling  a  case  of  EVD  Both   dressing   and   undressing   should   be   supervised   by   a   trained  member  of  the  team-­‐  (buddy  system).  These  instrucaons  should  be  displayed  on  the  wall  in  the  dressing  and  undressing  room:  

hjp://who.int/enLty/csr/disease/ebola/put_on_ppequipment.pdf?ua=1   hjp://who.int/enLty/csr/disease/ebola/remove_ppequipment.pdf?ua=1  

Page 29: Lessons learnt from ebola

Taking  puung  on  and  taking  off  PPE  •  “First-­‐on-­‐last  off”  •  Remove  the  most  contaminated  

PPE  items  first-­‐  gloves  •  Hand  hygiene  must  be  performed  

immediately  aver  glove  removal  –  Perform  hand  hygiene  whenever  ungloved  hands  touch  contaminated  PPE  items  

•  Be  careful  to  avoid  any  contact  between  the  soiled  items  (e.g.  gloves,  gowns)  and  any  area  of  the  face  (i.e.  eyes,  nose  or  mouth)  or  non-­‐intact  skin  

•  Discard  disposable  items  in  a  waste  container  

•  Use  a  buddy  to  help!  •  AVOID  CONTACT  WITH  THE  

OUTSIDE  OF  PPE!  

Page 30: Lessons learnt from ebola

Revised  CDC  guidelines  Sept  2014  

WHY  INCREASE  FOOT  PROTECTION?  

Page 31: Lessons learnt from ebola

 Work  and  personnel  flow  PaLents  

staff  

Support  services  ??  

Page 32: Lessons learnt from ebola

What  do  you  think  of  this?  

Page 33: Lessons learnt from ebola

MANAGING  EXPOSURE  TO  INFECTION    

•  Mucous  membranes  (e.g.  conjuncLva)  should  be  irrigated  with  copious  amounts  of  water  or  eyewash  soluLon  ONLY.      DO  NOT  USE  CHLORINATED  WATER!  

•  Follow  up  care,  including  fever  monitoring,  twice  daily  for  21  days  aver  exposure.    

•  Immediate  consultaLon  with  an  expert  in  infecLous  diseases  is  recommended  for  any  exposed  person  who  develops  fever  within  21  days  of  exposure.  

•  Contact  tracing  and  follow-­‐up  of  family,  friends,  co-­‐workers  and  other  paLents,  who  may  have  been  exposed  to  an  HF  virus  through  close  contact  with  the  infected  HCW  is  essenLal  

Page 34: Lessons learnt from ebola

South  African  Guidelines-­‐  well  prepared  

•  SA  always  had  good  guidelines  for  VHF-­‐  have  been  used  by  other  countries  across  the  world  

•  Now  modified  using  MSF,  Red  Cross,  CDC  guidelines-­‐  lijle  evidence  for  some  of  the  recommendaLons.  

•  HCW  at  risk  during  removal  of  PPE-­‐  use  a  buddy  system  

•  Keep  the  areas  clean  and  dry  •  Unnecessary  use  of  chlorine  spray  increases  risk  

Page 35: Lessons learnt from ebola

Are  you  prepared  

•  Go  to  the  ICAN  website  at    www.icanetwork.co.za  and  complete  the  surveymonkey  checklist  for  ebola  preparedness!    

Page 36: Lessons learnt from ebola

ICAN  PARTNERSHIPS  •  Funding  of  resource  centres  educaLon    programmes  for  HCW  in    –  Uganda  (Samsung)  –  CDC-­‐  teaching  in  Resource  Centres  –  Sierra  Leone  (London  Mining  Co)  –  Links  with  WHO-­‐    GOARN-­‐  involved  in  policy  making  with  WHO  

–  Geung  volunteers  from  across  UK  and  Europe  

•  Community  SMS/Text  messaging  communicaLons  –  Looking  for  mass  media  noyicaLon  

Page 37: Lessons learnt from ebola

ICAN  EBOLA  Training  Programme  •  Partnership  between  the  UIPC  and  ICAN    •  A  5  day  EVD  IPC  course  has  been  established    •  Will  be  run  in  Uganda  by  end  2014  •  Curriculum  for  EVD  IPC  course  

– Microbiology,  Epidemiology  and  Laboratory  Services  –  The  Paaent:  diagnosis,  IPC  management,  surveillance  –  The  HCW:  IPC  precauLons.  HH,  PPE,  Contact  precauLons,  reporLng  and  accident  management  

–  Support  services:  waste,  linen,  water  supply,  burial  and  Post  mortem,  transportaLon,  layout  of  ETU  

–  The  community  and  communicaaon  about  Ebola,  documentaLon  and  checklists  

www.ICANetwork.co.za  

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Summary  

•  Do  not  forget  the  basic  IPC  principles  

•  Good  IPC  is  of  the  essence-­‐  safe,  and  sensible!  

•  Keep  the  environment  clean  and  dry!  

•   Vaccines  are  coming!