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Global Research to Local Practice
Hilary EvansChief Executive, Alzheimer’s Research UK
Dementia – a global crisis
ARUK Defeat Dementia Report 2014
“I can think of no other disease where
innovation, including breakthrough
discoveries to develop a cure, is so badly
needed”
Dr Margaret Chan OBE
Director-General, World Health Organisation
Alzheimer’s Research UK
Increase awareness and provide information
Research strategy
Increasing awareness
Less than 1 in 4 people are aware that dementia is caused by brain diseases
People with dementia are at the centre of our work
People at the centre
Drug Discovery Alliance
Dementia Consortium
Accelerating access to treatmentsChallenge on Dementia
2020 Implementation Plan
ARUK Drug
Discovery AllianceDementia Consortium
Global Clinical
Trials Fund
International Dementia
Advisory Platform
Accelerating access to
treatments
ARUK
Ste
m C
ell
Rese
arch
Cen
treAR
UK fu
ndin
g
for b
asic
sci
ence
Improving our scientific
understanding
Translating scientific understanding into
promising treatments
Testing and trialling
promising treatments
Delivering outcomesthat matter most to people living with dementia and their
carers
Public health –
risk reduction and
awareness
START
Boosting drug discovery
• De-risking novel targets: applications from academics around the world for DC Pharma partners to adopt if successful
• Four current awards (UK, US, Italy, Luxembourg), one pending (UK)
Global Investment fund, managed by SV Life Sciences to discover and develop new treatments for dementia
UK Department of Health, ARUK, GSK, Lilly, Pfizer, J&J, Biogen, Takeda
Prime Minister’s challenge on dementia 2020
Dementia Research Institute
• Alzheimer’ Research UK is a founding partner of the DRI with the Medical Research Council and the Alzheimer’s Society
• The joint investment of £250M will create a national Institute that will bring together world-leading expertise in biomedical, care, public health and translational dementia research
Prime Minister’s challenge on dementia 2020
Funded 55 research projects at the Universities of Aberdeen, Dundee, Edinburgh and St Andrews
Over £5.6m research funded in Scotland
Research Network Centre in Scotland
Research funded in ScotlandResearch Network
DISCOVERY PRECLINICAL CLINICAL TRIALS (PHASE I-III) REIMBURSEMENTLICENSING COMMISSIONING ADOPTION
AND UPTAKE
Gaps in basic science
Accelerated Access Review
Accelerating access – looking at the path ahead
International Dementia Advisory Platform
14 -15 March 2017, Aberdeen
Thank you