Fatigue As A SymptomAre You Feeling Exhausted?

Fatigue

Physical or

mental exhaustion

As Symptom

It is very common and non-specific.So ,identifying significant underlying disease is difficult.

Non-organic causesMedications/ drugsMalignancyRespiratory causesCardiac causesHaematological causesEndocrine causes InfectionChronic inflammatory conditions

Causes

Non-organic causes

Work overload/ psychological stress

DepressionFribromyalgiaChronic fatigue syndrome

Medications / drugs

Beta-blockersChronic alcohol abuseBenzodiazepines & other

sedativesCorticosteroidsChemotherapeutic agents

Malignancy

Haematological

Solid organ

Disseminated

Respiratory Causes

Obstructive sleep apnoea

Chronic obstructive pulmonary disease (COPD)

Cardiac Causes

Congestive cardiac failure Bradyarrhythmias

Haematological causes

Anaemia

Haematological malignancy Eg- Lymphoma

Endocrine Causes

Hypothyroidism

Hypercalcaemia

Diabetes mellitus

Adrenal insufficiency

Hypopituitarism

Infection

Infectious monomucleosis

Tuberculosis

HIV

Infective endocarditis

Lyme disease

Chronic Inflammatory Conditions Rheumatic arthritis

Inflammatory bowel disease

Connective tissue disorders Eg- Systemic lupus erythematosus

Thank you!