Country study: Medicinal products in the Czech Republic

COUNTRY STUDYMedicinal products in the Czech Republic Analysis of registered products by ATC code Date: December 30, 2016

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CZECH REPUBLICNumber of products per ATC code by registration status Graphics created in IBM Watson


Approved treatments by ATC code

N03AX16Pregabalin1190 approved drugs

Number of registrations includes all strengths and dosage forms


Approved treatments by ATC code


Approved Cancelled Nutraceuticals Product after change (6 months)Specific therapeutic program app. Suspended

ALIMENTARY TRACT AND METABOLISM (A)


Alimentary tract: A01, A02 and A03 Stomatological preparations

Acid-related disorders: antacids, gastric-oesophageal reflux,

peptic ulcer

Drugs for functional GIT disorders: antispasmodics in combination with

psycholeptics


Alimentary tract: A04, A05 and A06 Anti-emetics and

antinauseantsBile and liver

therapy Drugs for constipation


Alimentary tract: A07, A08 and A09 Anti-diarrheals, intestinal anti-inflammatory

and intestinal anti-infective agents

Ant

i-obe

sity

dru

gs

Dig

estiv

es, i

ncl.

enzy

mes


Alimentary tract and metabolism: A10 (drugs used in diabetes)

metformin

glimepiride


Alimentary tract and metabolism: A11, A12, A14Vitamins

Ana

bolic

ste

roid

sMineral supplements


Alimentary tract and metabolism: A16

(other alimentary tract and metabolism products)


BLOOD AND BLOOD FORMING ORGANS (B)


Blood and blood forming organs: B01

(anti-thrombotic agents)

clopidogrel


Blood and blood forming organs: B01 Anti-hemorhagics: anti-fibrinolytics, vitamin K and other hemostatics

Anti-anemic preparations: iron, B12, folate, other


Blood and blood forming organs: B05, B06 Blood substitutes and perfusion solutions Anti-anemic

preparations: iron, B12,

folate, other ElectrolytesHypertonic solutions


CARDIOVASCULAR SYSTEM (C)


Cardiovascular: C01, C02Cardiac glycosides, antiarrhythmic drugs class I and III, cardiac

stimulants, vasodilatators for cardiac use, other cardiac preparations Antihypertensives


Cardiovascular: C03, C04, C05Vasoprotectives:

agents for the treatment of hemorrhoids, anal fissures, and varices, and capillary stabilizing agents

Perip

hera

l va

sodi

lata

tors

Diuretics


Cardiovascular: C07 and C08Antiarrhythmic drugs:

Calcium channel blockers Antiarrhythmic drugs: Betablockers

metoprololbisoprolol

carvedilol amlodipine


Cardiovascular: C09 (ACE inhibitors)Pe

rindo

pril

Ram

ipril

Perin

dopr

il +

am

lodi

pine

Ram

ipril

+ a

mlo

dipi

neLo

sarta

n Irb

esar

tan

Telm

isar

tan

Vals

arta

n +

diur

etic

sTe

lmis

arta

n +

diur

etic

s


Cardiovascular: C10 (lipid modifying agents)C10AA HMG CoA reductase inhibitors:• C10AA05 – atorvastatin • C10AA07 – rosuvastatin


DERMATOLOGICALS (D)


Dermatological agents: D01, D02, D03, D04, D05, D06

Emol

lient

s an

d pr

otec

tives

Antifungals

Trea

tmen

t of w

ound

s an

d ul

cers

Ant

ipru

iritic

s

Ant

ipso

riatic

s

Antibiotics and topical chemotherapeutics


Dermatological agents: D07, D08, D09, D10, D11

Corticosteroids for dermal use

Antiseptics, disinfectants

Med

icat

ed d

ress

ings Anti-acne

preparationsOther


GENITO-URINARY AGENTS AND SEX HORMONES (G)


Genito-urinary agents and sex hormones: G01, G02, G03

Gynecological anti-infectives and

anti-septics

Other gynecological

agents

Sex hormonesG03A – hormonal contraceptives for systemic use


Genito-urinary agents and sex hormones: G03Sex hormones and modulators of the genital system: • hormonal contraceptives for systemic use• androgens, estrogens, progestogens• gonadotropins and other ovulation stimulants• antiandrogens


Genito-urinary agents and sex hormones: G04(urologicals)

Solif

enac

in

Sild

enaf

ilTa

dala

fil

Tam

sulo

sin

Fina

ster

ide


SYSTEMIC HORMONAL PREPARATIONS (H)


Systemic hormonal preparations: H

Pituitary and hypothalamic hormones and their analogues

Corticosteroids for systemic use

Thyroid hormones

Calcium homeostasis

Panc

reat

ic h

orm

ones


ANTIINFECTIVES FOR SYSTEMIC USE (J)


Antibacterials for systemic use: J01J01A – Tetracyclines J01B – Amphenicols J01C – Beta-lactams, penicillines J01D – Other beta-lactams J01E – Sulfonamides and trimetoprim

J01F – Macrolides, lincosamides, streptogramines J01G – Aminoglycosides J01M – Quinolones J01R – Combinations J01X – Other

Linezolid

Amoxicillin + enzyme inhibitor

Cefuroxime

Clarith

romyc

ine


J02 – Antimycotics for systemic use J04 – AntimycobacterialsJ05 – Antivirals

Linezolid

Antiinfectives for systemic use

Fluconazole

Voriconazole


Antiinfectives for systemic use: J06, J07

Immune sera and immunoglobulins Vaccines


ANTIINEOPLASTICS AND IMMUNOMODULANTS (L)


Anti-neoplastic agents: L01Alkylating agents Anti-metabolites Plant alkaloids Cytotoxic

antibioticsMethotrexate

BendamustineCapecitabine

Temozolomide


Anti-neoplastic AgentsL01X (Other)

Imatinib


Antineoplastic and immunomodulating agentsEndocrine (L02) & Immunostimulants (L03)

Bica

luta

nide

Anas

trozo

leLe

trozo

le

pegi

nter

fero

n al

fa-2

b

filgr

astim


Immunosuppressants: L04Selective immunosuppressants TNF-ɑ

inhibitorsInterleukin inhibitors

Cal

cine

urin

inhi

bito

rs

Other


MUSCULO-SKELETAL SYSTEM (M)


Musculo-skeletal system: M01, M02, M03Anti-inflammatory, anti-rheumatic agents Topical muscle

and joint pain Muscle relaxants

Ibuprofen

Diclofenac Etoricoxib

Diclofenac


Musculo-skeletal system: M04, M05, M09Anti-gout

preparationsDrugs for the treatment of bone diseases Other drugs for

musculo-skeletal disorders


NERVOUS SYSTEM (N)


Nervous system: Anesthetics (N01) and Analgesics (N02)

Oxy

codo

ne

Oxy

codo

ne +

nal

oxon

e

Fent

anyl

Bup

reno

rphi

ne

Tram

adol

Ta

pent

adol

Tr

amad

ol +

com

bina

tions

Par

acet

amol

P

arac

etam

ol +

com

b.

Sum

atrip

tan


Nervous system: Anesthetics (N01) and Analgesics (N02)

Oxy

codo

ne

Oxy

codo

ne +

nal

oxon

e

Fent

anyl

Bup

reno

rphi

ne

Tram

adol

Ta

pent

adol

Tr

amad

ol +

com

bina

tions

Par

acet

amol

P

arac

etam

ol +

com

b.

Sum

atrip

tan


Nervous system: Anti-epileptics (N03) and Anti-Parkinson drugs (N04)

Lam

otrig

ine

Topi

ram

ate

Gab

apen

tinLe

vetir

acet

am

Pre

gaba

lin

Levo

dopa

+ d

ecar

boxy

lase

in

hibi

tor +

CO

MT

Pra

mip

exol

eR

opin

irole


Nervous system: Psycholeptics (N05)Antipsychotics Anxiolytics Hypnotics and

sedatives

Arip

ipra

zole

Que

tiapi

neO

lanz

apin

e

Ris

perid

one

Zolp

idem


Nervous system: N06Antidepressants Psychostimulants

NootropicsAnti-ADHD drugs

Anti-dementia drugs

• AB04 – citalopram• AB06 – sertraline • AB10 – escitalopram • AX11 – mirtazapine • AX16 – venlafaxine • AX21 – Duloxetine

Don

epez

il

Mem

antin

e


Nervous system: N07Pa

rasy

mpa

tom

imet

ics

Addictive disorders Anti-vertigo drugs Other

Nic

otin

e

Bet

ahis

tine


ANTIPARASITICS (P)


Antiparasitics, insecticides and repellents: P

P01 Antiprotozoals P02 Anthelmintics P03 Ectoparasiticides


RESPIRATORY SYSTEM (R)


Respiratory: R01 and R02

Nasal preparations Throat preparations


Respiratory:Drugs for obstructive airway diseases (R03)

Montelucast


Respiratory: R05, R06 and R07 Cough and cold preparations Antihistamines for systemic use Other

Levocetirizine Desloratidine


SENSORY ORGANS (S)


Sensory organs: Ophthalmologicals (S01), Otologicals (S02) and combinations (S03)


VARIOUS (V)


Various: V01, V03, V04 and V06Allergens All other therapeutic products

Dia

gnos

tic p

rodu

cts

Gen

eral

nut

rient

s (n

utra

ceut

ical

s)


Various: All other non-therapeutic products (V07), Contrast media (V08), and Diagnostic radiopharmaceuticals (V09)


Various: Therapeutic radiopharmaceuticals (V10), and all other (V11 and V12)


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Country study: Medicinal products in the Czech Republic