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I o n a n a l y s i s
Networked Titration Data System
Networked Titration Data System
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• tiamo points the way 4/5
• tiamo at a glance 6
• tiamo makes work a pleasure 7
• tiamo brings you more... 8/9
• ... and more... 10/11
• ... and even more 12/13
• Future-proof thanks to client-server option 14/15
• Unlimited flexibility 16/17
• Further innovative features of tiamo 18/19
• Prepared for the audit 20/21
• Ordering information 22
• System requirements 23
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tiamo points
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tiamo – titration and moretiamo is a control and database software for titrators anddosing devices as well as for complete laboratory auto-mation up to a client-server system. This is why the nametiamo stands for «titration and more» – tiamo can domore than just titrate. tiamo is a titration network (NTDS= Networked Titration Data System).
tiamo is the result of Metrohm’s largest and most modernsoftware project. With its numerous innovations, userfriendliness and flexibility, tiamo is the leading softwarepackage for titrations.
Bringing together what belongs togethertiamo is the successor to TiNet and Workcell. Metrohmnow offers you worldwide a uniform software package for laboratory automation. This means that, as an interna-tionally operating company, all your subsidiaries can use asingle software platform in their laboratories for titrations.Your benefits: data and methods can be exchangedwithout any losses.
tiamo brings together the world of Titrinos and the newTitrando system generation. In the software sector suchcompatibility with existing Metrohm instruments is not justa matter of course. The whole Titrino family, which waspreviously also controlled by TiNet, can continue to beoperated under tiamo, and this after being on the marketfor more than ten years! That's how Metrohm protectsyour investments!
the way
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tiamo at a glance
tiamo is easy to use• New, progressive software interface• Freely configurable desktop thanks to new Layout Manager• Powerful report generator• Automatic database backup• Graphical method editor
tiamo communicates• Real client-server database software• Real parallel titrations• Data export in XML, etc.• E-Mail function for results and messages
tiamo overcomes boundaries• Titrando and Titrino can be used in one system• Central user administration• Complete traceability of all results• Extended method commands• Developed and validated for cGxP
tiamo makes work a pleasure
Your new workplaceThe modern user interface makes it easy foryou to familiarize yourself with tiamo. All thecommands and controls are to be found whereyou expect them to be.
The tiamo bar allows direct access to the fourprogram parts of tiamo:• Workplace• Database• Methods• Configuration
These buttons may be visible or concealed,depending on the user’s access rights.
The information windows are in the center. Inthe run window you can comfortably enter allthe sample data, whether for a single sampleor for a whole sample series.
The live display window informs you aboutfreely definable method instructions and showsthe live curve during the titration. The methodwindow provides information about the cur-rent method status. If necessary, you have liveaccess to the method parameters. In the reportwindow you can view the current reports ofthe last determinations.
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tiamo brings you more...
Layout Manager – each user gets his or her own tiamoWith the novel Layout Manager the user interface can be arranged so that each user only seesthose windows that are really necessary. This saves time; cluttered-up screens are now a thing ofthe past.You can also freely define what information is to be shown in the windows.
Making four from one – parallel titrationsYou can subdivide the user interface even further to create up to four independent workplaces. In this way you can elegantly control different titration systems that are all connected to the samePC. And all this in parallel – and, if necessary, with different users. This means that tiamo offersmaximum utilization of the analytical system.
tiamo carries out tedious routine workDo you enter your sample data manually or do you use a barcode reader? In both cases tiamohelps you to fill in the sample table. Continually repeated sample identifications can be saved astext templates. tiamo also takes care of the sequential numbering. Importing the sample table?Just let your LIMS draw up the sample table for tiamo! Avoid surprises when using a samplechanger – let tiamo check the sample table for sample weights that are too high. You can use the sample assignment table to link sample numbers with methods. This makes your tiamo theeasiest to operate routine system in your lab!
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... and more...
Curve windowThe titration curve is shown for eachdetermination. The curve layout can befreely defined. Do you want to includethe titration curve in a Word document?No problem.
DatabaseThe database is a further trump from tiamo.Not only your determinations, but all thesettings, methods and user information arestored in the tiamo database and protectedagainst manipulation and loss.
Data ManagerManage your data in the determination over-view, where you can obtain the most importantinformation about any sample in tabular andfreely configurable form. Powerful search andfilter tools provide support. Even among thou-sands of titrations you are sure to find your ownparticular determination – in just a few seconds.
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Total traceabilityWho carried out a determination and when?What titrator was used? What alterationshave been made to the determination and bywhom? The unique traceability of the tiamosystem leaves no questions unanswered.
Immediately recognize what mattersProvide yourself with a quick overview inthe results window. No long searching for the result – here you will find all theimportant results and calculation details in compact form.
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... and even more
Determination reprocessingWrong sample weight? No problem. With the reprocessing function the sample weight can bequickly corrected or a calculation formula adapted. Endpoint not recognized correctly? tiamocan help here as well. You can evaluate the curve again. And you do not have to worry about the documentation. tiamo automatically records all alterations.
Historytiamo manages all the versions of a determination. The history function provides you with thenecessary overview.
SignaturesYou can provide digital signatures for the determinations. tiamo offers signatures at two levels. Assoon as a determination has a level 2 signature, the data are protected against further alterations.
Report generatorThe unique report generator allows you toarrange your analytical report layout as youwant. You can adapt one of the many reporttemplates to suit your particular requirements.There is no limit to what you can do; you caninclude any imaginable information in yourtiamo report.
Do you need an analysis report? Just mark thedetermination in the database, select a reporttemplate and off it goes. You can even sendyour analytical reports comfortably by E-Mail!
Data exportDo you want to process your data further inExcel or are you planning to include tiamoin a LIMS? No problem – tiamo offers you awide range of export formats, including themodern XML format. All imaginable officeapplications, databases and long-termarchiving programs are available for yourdata. tiamo's flexibility is unbeatable!
Control charttiamo can produce a control chart for yourdeterminations at the touch of a button.Present your measured values in chrono-logical order. Print them out, save them as a pdf document or use them in Officeapplications. Ready!
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Future-proof thanks to client-server option
Client-server databaseIn the simplest case you just install the database on your local computer. tiamo will grow togetherwith your requirements. As soon as data security and central data management make it necessary,you can set up tiamo in a client-server configuration.
Install the database on a server and all measuring and office computers will act as clients. Allresults are stored centrally and can be viewed and reprocessed by all client PCs. In addition, allclients access the same pool of methods.
Data securitytiamo supports you in safeguarding your data. Activate the automatic backup function; tiamowill then automatically make complete copies of all determinations and configurations. This meansthat if the worst comes to the worst you can recover all your settings, system configurations anddeterminations within a very short time.
Central controlIn addition to data security, the client-server version provides you with the possibility of centraluser administration. From your office you can activate new users, assign rights of access to dataand methods or implement security policies. The administration of titration systems has never been so simple.
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Example of a client-server system comprising four lab workplaces and two office PCs.
Unlimited flexibility
Method editor – clarity creates orderThe block-by-block presentation of a method is clear and tidy. This makes operation child’s play.You just make a selection from the list of method templates provided, quickly insert a calculationtemplate, add a report template and you can start the titration. It’s as easy as that!
Quick access to detailsThe detailed parameters can be accessed quickly with a double-click on the particular methodblock.
You regard increased flexibility as being the key to solving your future problems?Then tiamo is the ideal tool for you. Flexibility is one of the main advantages of this softwarepackage. You can compile measuring commands, titrations, queries, calculations, database entries,export instructions and sample changer commands, and this in any sequence, according to themotto: «Nothing is impossible».
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START
Main track
MOVE
Move to sample
DET pH
DET pH
PUMP
Rinse electrode
END
Main track
SERIES END
Series end track
MOVE
Cond beaker
LIFT
Work position
END
Series end track
SERIES START
Series start track
CAL LOOP pH
Calibration
MOVE
Buffer
CAL MEAS pH
CAL MEAS pH
MOVE
Move rinse beaker
PUMP
Rinse buffer
LIFT
Shift position
END
Series start track
EXIT
Exit track
CALC
Calculations
REPORT
Report
DATABASE
Database
EXPORT
Export
END
Exit track
Titration and moreIn addition to the commands that are necessary to control the measuring, dosing, titrating andautomation devices, tiamo also lets you:• Show messages on the screen to guide the user through a sample preparation procedure.• Ask for the sample size and monitor result limits.• Assign the results to different databases.• Print out a result report and send it by E-Mail.• Inform your colleagues automatically by E-Mail about any interference to the titration system.• Program recurring sequences and decisions.
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Further innovative features of tiamo
ConfigurationAll the tiamo settings are made in the configuration section.
Plug and playOur modern USB devices ensure that all connected devices appear in the devices window. Connect up – ready! All device data are adopted automatically.
Titrants under controlSimple organization of your titrants and solutions:• In addition to the basic information, tiamo manages all the data required for traceability.• tiamo even checks the working life and titer validity for you.• If you use our uniquely intelligent dosing systems with the new «Chip on board» technology,
tiamo will prevent mix-ups.
Sensor Organizertiamo also manages your sensors perfectly. In this way you can ensure that all calibration intervalsare observed and only perfectly functioning electrodes are used. The calibration history of eachsensor is saved to ensure complete traceability.
Safely managedIf a computer crash should occur then your system will be quickly ready for use again if you haveautomatically saved all your configuration settings. This means that «disaster recovery» poses noproblems.
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Networked Titration Data System
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Prepared for the audit
tiamo guarantees data securityWhether GMP or GLP rules, regulations on the security of electronic data (e.g. 21 CFR Part 11) or the requirement that all results are traceable – tiamo has been developed from the very start tomeet all these requirements and therefore sets new standards.
Security has priorityProtect your data with the comprehensive security functions of tiamo. Let tiamo or Windowsmonitor the passwords. Define the rules for assigning digital signatures and control access to yourdata.
User administrationAdd new users to the list from your office computer – tiamo assists you in doing this. Arrange theaccess rights of each user in accordance with your company’s security policy. tiamo sets no limits,but will convince you with its unique flexibility.
Complete Audit TrailEach action performed by a tiamo user is stored automatically in the Audit Trail. This means thatyou can obtain a detailed protocol about who did what and when. Data for an audit can beprepared by pressing a button.
Version checkAll data records are stored in tiamo together with their version. Protect your results againstaccidental or deliberate manipulation. Use the history function to show each version of your data.All alterations to electronic data are documented automatically – audits can no longer worry you.
TraceabilityBe absolutely certain and place your confidence in the complete traceability of Metrohm softwareand hardware for your titrations. Each data record contains all the raw data necessary to ensuretraceability. Unique in the world is the fact that each component used to generate the data isdocumented.
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Ordering information
tiamo is available in different versions and offers a suitable system for every application.
3) 6.6056.001 tiamo multi: 1 additional license6.6056.002 tiamo multi: 5 additional licenses6.6056.003 tiamo multi: 10 additional licensesThe serial no. of the tiamo multi version is required for ordering additional licenses!
4) 6.6056.106 tiamo 1.0 light upgrade to full (1 license)6.6056.107 tiamo 1.0 light upgrade to multi (3 licenses)
5) 6.6056.108 tiamo 1.0 full upgrade to multi (3 licenses)
License policy for the client-server versionMetrohm offers you a favorable license program. tiamo multi uses runtime licenses, i.e. a licenseis only required for those tiamo installations that are in use at the same time. In practice thismeans that you do not need to purchase a separate license for your office computer. As a result,when you have finished making measurements in the laboratory you can continue to use tiamoin your office without needing a further license.
Free-of-charge updates!You really should choose tiamo. As a Metrohm customer you will receive all future tiamosoftware updates free of charge. You will also profit from new and extended tiamo functions.
1) Please note that a balance or a barcode reader also counts as a connected device.
Titrandos 808, 809, 835, 836, 841Titrinos 702, 716, 718, 719, 720, 721, 736, 751, 758, 784, 785, 794, 795,
798, 799Measuring instruments 712KF Coulometers 756, 831Sample changers 730, 774, 778, 789, 814, 815Others 846, balance, barcode reader...
tiamo 1.0 light tiamo 1.0 full tiamo 1.0 multiOrder number 6.6056.101 6.6056.102 6.6056.103Max. no. of devices per PC 21) Unlimited UnlimitedSupported devices See2) See2) See2)
Dialog languages English, German English, German English, GermanMeets the requirements • •of FDA 21 CFR Part 11User administration • • •Security policy • •Audit Trail • •Client-server support •Licenses 1 1 3Additional licenses (optional) •3)
Data export to LIMS • •Parallel titration • •Upgrade available •4) •5)
2)
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System requirements
Minimum system requirements• Processor Pentium 4; clock rate 1 GHz• Working memory 512 MB• Free hard disk memory 150 MB for program• Free data memory 2 GB (for approx. 5000 determinations)• Operating system Windows 2000 SP1, Windows XP Professional• Connections free USB connection and/or free serial connection (RS 232C)
Additional system requirements for tiamo server• Data line 10 MBit/s• Operating system Windows 2000 SP1, Windows XP Professional, Windows
2000/2003 Server
I o n a n a l y s i s
Metrohm Ltd.CH-9101 Herisau/SwitzerlandPhone +41 71 353 85 85 Fax +41 71 353 89 01 [email protected]
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