1

CURRICULUM VITAE

SAEED SAEED ALGHAMDI

Consultant and Professor

of Pharmacology and Toxicology

PhD, MSc, DIC, HPM Dip., AIBMS, CBiol MIBiol, UWCM Dip., SNHS Dip

(Kinesiology), SNHS Dip., (Reflexology), ), SNHS Dip., (Aromatherapy), FAACT,

MIHM

UK and EUROTOX Registered Toxicologist

16040-A-R-Saudi commission for health specialties ID: 05

AUGUST 2016

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PERSONAL DETAILS

Name: Saeed Saeed Alghamdi

D.O.B:13/09/1969

Nationality: Saudi

Gender: Male

Marital status: Married

Address: P.O.Box 7951, Makkah, Saudi Arabia

Telephone (Home/Fax): 00966 2 5584564

(Mobile): 00966 54789119/ 0557303715

E-mail: dr.s.s.alghamdi@gmail.com

Website: www.uqu.edu.sa/sskghamdi

http://en.wikipedia.org/wiki/User:Drssalghamdi

PERSONAL PROFILE

I am a Pharmacologist/ Toxicologist with broad scientific knowledge and technical,

teaching and administrative experiences in different area of medical sciences, having

a particular interest in BIOCHEMICAL TOXICOLOGY with many publications.

Self-motivated, and has the appropriate managerial education to lead and motivate

others utilizing modern approaches of managing and implementing change. Through a

wide communication network and strong commitment towards environmental-friendly

safe practice, human resources development and as a member of national and

international societies and institutes, has the potential to initiate broad co-operation.

Has an excellent ability to use the internet, prepare reports, plan projects and deliver

presentation on specialised scientific subject, individual development and quality

management.

QUALIFICATIONS

Bachelor of Medical Sciences (BSc) from Faculty of

Medicine, Umm Al-Qura University, Makkah, Saudi Arabia, 1990-1994.

Grade: Very good (3.79/5)

The main subjects: Anatomy, Histology, Histopathology, Clinical Microbiology,

Clinical Biochemistry, Clinical Virology, Environmental Health, Laboratory

administration, Medical Parasitology, Medical Immunology, Medical Physiology,

Medical Endocrinology, Nutrition, Pharmacology and Toxicology.

Project: Hormonal Profile of Infertile Makkans (Published)

Master of Sciences (MSc) in Toxicology from

Imperial College School of Medicine (University of London),

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1997/1998.

Grade: Pass

Experimental Pathology Modules covered; General laboratory techniques, Molecular

biology techniques, Cells and tissues, Cells and tissues damages, Inflammation,

Wound healing, Cells adaptation, Vascular diseases, Neoplasia, and Systemic

pathology.

Biochemical mechanisms modules covered; Introductory toxicology, The fate of

foreign compounds in the body, Methods of chemical analysis, Biochemical and

pharmacological effects of foreign compounds, Pharmacokinetics, Basic mechanism

of toxicity, Factors affecting toxicology, Target organs toxicity (liver, kidney, lung,

blood, Immunotoxicity), Specific classes of toxic compound, Chemical

carcinogenesis, Teratogenesis, Clinical toxicology, Epidemiology, Toxicity testing,

Assessment of exposure, Risk assessment, and Regulatory requirements.

Project: “Differences in P450 Expression In A Rat Model of The Debrisoquine 4-

Hydroxylase Polymorphism”, supervised by Dr. Robert Edwards.

Diploma of Imperial College (DIC) in toxicology, 1998/ 1999

Diploma in Health Planning and Management from

Birkbeck College, University of London, September 2000

Grade: Merit

The main subjects: Finance and Management of Health, Health Policy and Health

Promotion, and Health service Research Method.

Diploma in Medical Toxicology, University of Wales College of

Medicine, June 2002

PhD from the University of London (January 2003)

Subject: Toxicology

PhD Project title: The Role of Cytochrome P4502E1 in Solvent and Oxidant

Induced Nephrotoxicity, supervised by Pro. Magdi M Yaqoob MD, PhD,

FRCP.

Certificate of Advanced course in Forensic Medicine, Glasgow University,

2002.

Assistant Professor, Faculty of Medicine, Umm Al-Qura University, since

June 2004 till July 2009.

Associate Professor of Pharmacology/ Toxicology, Faculty of Medicine,

Umm Al-Qura University, since July 2009 to April 2013.

Professor of Pharmacology/ Toxicology, Faculty of Medicine, Umm Al-

Qura University, since April 2013 till present.

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TECHNIQUES ACQUIRED

General lab. Techniques; Tissue processing and staining for light

microscopy, Immunohistochemistry (IHC) for light microscopy and

electronic microscopy, Transmission and Scanning electron

microscopy, Autoradiography, In Situ Hybridisation, Cell culture,

Ames test, Comet Assay, High Performance Liquid Chromatography

(HPLC), Thin Layer Chromatography (TLC), Gas Chromatography

(GC), Gas Chromatography/ Mass Spectrometry (GC/MS), Toxi Lab.,

Electrophoresis, TUNEL, Lipid peroxidation measurement, caspases

activity analysis, Cytochrome P450 activity measurement, DNA

fragmentation, and DNA laddering assessment.

Molecular biology techniques; RT-PCR, Western, Northern, Southern

and Dot blotting, Assays. DNA preparation, Restriction enzyme

digestion, Ligation and cloning in plasmid vectors, Agarose gel

electrophoresis, sequencing and acrylamide gel electrophoresis.

RESEARCH EXPERIENCE AND SUPERVISION

1- A project of 6 months conducted at Faculty of Medicine and Medical

Sciences, Umm Al-Qura University, Saudi Arabia January to June 1994. The

title of the project was (HORMONAL PROFILE OF IMPOTENT

MAKKANS), supervised by Professor Zulfaqar A. Khan, it was published as

described in publication. In this context we examined serum concentrations of

nine hormones in infertile and fertile male Makkans using, including

luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin,

estrogen, progesterone, testosterone, thyroxin (T4), triiodothyronine (T3) and

thyroid stimulating hormone (TSH). Conclusion: Infertility was implicated in

21% of the population with correlated abnormalities of gonadotrophins,

thyroid, TSH, and testosterone. Hypothyroidism was established in 35% and

hyperthyroidism in 14% of the infertile population, where 28% of thyroid

abnormality constituted an independent infertile group. Hyperprolactinaemia

associated with low levels of LH and testosterone signifies a cluster of 28%,

while 14% of testosterone deficiency alone was causal for infertility.

However, infertility in 9% of the patients examined might have been

psychogenic in nature

2- A project of 4 months conducted at Imperial College School of medicine

May to August 1998. The tile of the project was (DIFFERENCES IN P450

EXPRESSION IN A RAT MODEL OF THE DEBRISOQUINE 4-

HYDROXYLASE POLYMORPHISM”, supervised by Professor Alan

Boobis. It was a requirement for MSc course in toxicology. The purpose of

this study was to investigate the level of expression of the P450 isoenzymes

CYP1A2, CYP2C12, CYP2C13, CYP3A1, CYP3A2 and CYP2E1 in the liver

of male and female Dark Agouti (DA), Sprague-Dawley (SD) and Wistar rats.

This was achieved by immunoquantitation by dot blotting using highly

specific antibodies against each P450 isoform. Conclusion:

immunoquantification using dot blotting was successful and demonstrated

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sexes and strains differences in the levels of several P450 enzymes between

sexes and strains. This variation important implication in the use of different

rat strains studying drug metabolism.

3- A dissertation was submitted to Birkbeck College as a requirement for the

Diploma in Health Planning and management. The title was (A Medical and

Toxicological Overview of Organic Solvents), Supervised by Professor Magdi

Yaqoob. The dissertation aimed to overview the toxicological effects of

organic solvents on different body compartments and the management

procedures. Conclusion: The study supports the concept of industrial solvent

exposure and the development of many health problems. Therefore special

precaution must be taken when handling, using, transporting and storing

solvents. Workers must be aware of the hazards of solvents and be subjected

to frequent monitoring to assess the level of exposure. Environmental

protection agencies must be up to date with any toxicological studies of

organic solvents and take the proper action to safeguard the environment.

Finally, the evaluating physician however must be able to differentiate

between solvent related and non-solvent related toxicity.

4- Three years at St Bartholomew’s and The Royal London School of

Medicine and Dentistry (January 2000 to January 2003), under the supervision

of Professor Magdi Yaqoob (MD, PhD, FRCP).

5- Seven months as a postdoc at St Bartholomew’s Hospital (January 2003 to

July 2003).

6- Supervisor of four male students from the Faculty of Applied Medical

Sciences, Umm Al-Qura University for a project entitled "Inhibition of

calcium oxalate nephrotoxicity with Cymbopogon schoenanthus ( Al-

Ethkher) , (2005/2006).

7- Supervisor of five female students from the Faculty of Applied Medical

Sciences, Umm Al-Qura University for a project entitled a project entitled

"Protective effect of Nigella sativa against viral hepatitis B,

(2006/2007).

8- Supervisor of four male students from the Faculty of Applied Medical

Sciences, Umm Al-Qura University for a project entitled a project entitled

"Inhibition of calcium oxalate formation with water of Zamzam",

(2008/2009).

9- Renal and hematological disorders in workers chronically exposed to

aromatic hydrocarbons (Sponsored by Umm Al-Qura Univ. 2009-2011).

REVIEWING BOOKS AND MANUSCRIPTS

1- Reviewer of a manuscript entitled (The antibiotic gentamicin induces

apoptosis in LLC-PK1: involvement of lysosomal and mitochondrial

pathways) by Servais H et al, sent to the Kidney International Journal for

publication (2004).

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2- Reviewer of a manuscript entitled (Effect of Shiga toxin and

lipopolysaccharide on glutathione redox state in cultured human renal

epithelial cells) by Osamu Kikuchi et al, sent to the Kidney International

Journal for publication (2006) .

3- Antihepatotoxic Activity Of Aqueous Methanolic Extract From The Seeds

Of Tamarix Amplexicaulis. By Adel Assiri et al., Umm Al-Qura Journal for

Science Medicine and Engineering 2005.

4- A Book entitled "Antibiotic ant Family" presented to Umm Al Qura

University for publication (2007).

5- A paper entitled " Phosporylation of STATs at Ser727in renal proximal

tubular epithelial cells exposed to cadmium. By Nakagawa et al, for

publication in Environmental Toxicology and Pharmacology, April (2007).

6- Reviewer of manuscript entitled (Overlapping ligand specificity of P-

glycoprotein and human alpha1-acid glycoprotein evidences and implications.

By Ferenc Zdila to be published in Current Drug Metabolism, April (2007).

7- Reviewer of manuscript entitled (Comprehensive identification of

cytochrome P450 isoforms from solubility-based fractionated rat

liver microsomes) By Hidenori Yamanaka1, Masahiro Takeyoshi1,

Yasushi inobe1, Yoshikuni Yakabe1, Mineo Takatsuki1, Hisaya

Sato to be published in Drug metabolism Letters August (2007).

8- Reviewer of manuscript entitled (A New Method to Measure P-gp MDR1

Activity) By Dr. Takaharu Mizutani and Masatoshi Masuda to be

published in Drug metabolism Letters September (2007).

9- Reviewer of manuscript entitled (Ingestion of a Newly Described North

American Mushroom Species from Michigan Resulting in Chronic Renal

Failure): Cortinarius orellanosus to be published in Clinical Toxicology

Journal (2010).

10- Reviewer of manuscript entitled "13C-methacetin breath test and

phenacetin O-deethylation test have great intra-individual variability in

healthy volunteers” was received by us for publication. We will be highly

obliged if you could find time to review the manuscript. Please find the

abstract below" to be published in International Research Journal of

Pharmacy and Pharmacology (Feb 2012).

11- Reviewer of manuscript entitled "Organophosphate Poisoning: 10 years'

Experience at a Tertiary Care Hospital in Saudi Arabia" to be published in

Saudi Journal of Medicine & Medical Sciences (May 2014).

12- Reviewer of manuscript entitled “Socio-Economic Impact Of Khat In

Mana District, Jimma Zone, South Western Ethiopia” to be published in

Agric. Food Sci. J, (Dec 2013).

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13- Phytochemical and anti-diarrhoeal properties of methanolic leaf extract of

Maerua crassifolia Forssk". to be published in European Journal of

Medicinal Plants (May 2014)

14- Reviewer of manuscript entitled "Characterization of a Trpc6 transgenic

mouse associated with early onset FSGS", to be published in

British Journal of Medicine and Medical Research (June 2014).

15- Reviewer of a manuscript entitled "Screening The Antiurolithiatic

Efficacy of Achyranthes aspera L. and Bryophyllum pinnatum" to be

published in British Journal of Pharmaceutical Research Lam (Sept 2014).

16- Reviewer of manuscript entitled “A review on Barleria prionitis: its

pharmacognosy, phytochemicals and traditional use” to be published in

OPEN peer review system in (Sept 2015).

17- Reviewer of a manuscript entitled “Phytochemical study of a species with

ethnopharmacological interest: SIDERITIS ROMANA L.” to be published in

European Journal of Medicinal Plants in (January 2016).

18- Reviewer of a project entitled “possible ameliorative role of L-carnitine

and curcumin extract against toxicity and oxidative stress induced by

Fipronil” presented to Taif University for sponsorship, Febrauary 2016.

19- Reviewer of a project entitled “Effect of Tadalafil On Liver Ischemia-

Rreperfusion Injury Induced Experimentally In Rats”, presented to Aljuf

University for sponsorship, April 2016.

20- Reviewer of a project entitled “Chemical Composition and Antibacterial

Activities of Essential Oil of the Leaves of Callistemon citrinus from Ethiopia” to be

published in European Journal of Medicinal Plants July 2016).

21- Reviewer of a project entitled “SYNTHESIS AND CHARACTERIZATION OF

NOVEL XYLOPIC ACID DERIVATIVES” to be published in American Chemical

Science Journal (July 2016).

PUBLICATIONS

BOOKS

Published:

1- Heavy Metals and Minerals: Toxicity and Management, Mars Publishing

agent, 2005.

2- Drugs of abuse at a glance, Al-Saedi Press, 2009

ARTICLES

Published:

Z. A. Khan and S. S. Al-Ghamdi. Hormonal Profile of Infertile Makkans,

International Urology and Nephrology, 30 (4): 499-505 (1998).

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Saeed S. Al-Ghamdi, Martin J. Raftery and Muhammad M. Yaqoob. Acute

solvent exposure induced activation of cytochrome P4502E1 causes proximal

tubular cell necrosis by oxidative stress, Toxicology in Vitro 17: 335-341

(2003)

Saeed S. Al-Ghamdi, Martin J. Raftery and Muhammad M. Yaqoob. Organic

Solvent-Induced Proximal Tubular Cell Toxicity via Caspase-3 Activation.

Journal of Toxicology Clinical Toxicology 41(3): 967–971 (2003).

SAEED S. AL-GHAMDI, MARTIN J. RAFTERY, MUHAMMAD M.

YAQOOB. Organic Solvent-Induced Proximal Tubular Cell Apoptosis Via

Caspase-9 Activation, Environmental Toxicology and Pharmacology 16 (3),

147-152, 2004.

SAEED S. AL-GHAMDI, PRABAL K. CHATTERJEE, MARTIN J.

RAFTERY, CHRISTOPH THIEMERMANN, MUHAMMAD M. YAQOOB.

Role Of Cytochrome P4502E1 Activation In Proximal Tubular Cell Injury

Induced By Hydrogen Peroxide, Renal Failure 26:103-10, 2004.

SAEED S. AL-GHAMDI, MARTIN J. RAFTERY, MUHAMMAD M.

YAQOOB. Toluene and P-Xylene Induced LlLC-PK1 Apoptosis, Drug and

Chemical Toxicology 27 (4): 425-32, 2004.

SAEED S. AL-GHAMDI. Organic solvent Toxicity and Management, Arabic

Journal For Security Studies and Training, 42: 236-266, 2006 (In Arabic

language).

SAEED S. AL-GHAMDI. International efforts for preventing drug precursors

in building up drugs., Umm Al Qura University Journal for science medicine

and engineering, 18 (2), 41-67, 2007 (In Arabic language).

SAEED S. AL-GHAMDI. Inhibition of calcium oxalate nephrotoxicity with

Cymbopogon schoenanthus ( Al-Ethkher). Drug metabolism letters 1(4): 241-

244, 2007.

SAEED S. AL-GHAMDI. Time and Dose Dependent Study Of Doxurubicin

Induced Du-145 Cytotoxicity. Drug Metabolism letters, 2: 56-62, 2007.

SAEED S. AL-GHAMDI. Nigella Sativa Seeds Protect From Viral Hepatitis

B Virus Infection. Current topics In Pharmacology, 12,1101-104, 2008.

SAEED S. AL-GHAMDI. N(2-hydroxylpropyl-methacrylamide attached

doxorubicin induces cytotoxicity to prostate cancer cell line DU145, Toxicol

Mech Methods. 2008;18(5):419-24

SAEED S. AL-GHAMDI. Evidence for cytochrome P450 2E1 as a source for

catalytic iron in oxidant-induced nephrotoxicity. Umm Al Qura University

Medical Journal. 1 (1), 23-32, 2010.

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Adnan Ali Baddour, Anas Serag and SAEED S. Al-GHAMDI Dablool.

Improving Laboratory Test-Ordering with Information Technology.

International Journal of Clinical Medicine, 2012, 3, 446-458.

SAEED S. Al-Ghamdi. The Reproductive and Thyroid Hormonal Profile of

Khat (Catha edulis) Chewers. Pharmacology & Pharmacy, 2012, 3, 447-452.

SAEED S. Al-GHAMDI. Inhibition of calcium oxalate nephrotoxicity with

Zamzam water. Open Journal of Preventive Medicine. Vol.2, No.1, 67-71

(2012).

Anas Serag Dablool and SAEED S. AL-GHAMDI. Enterotoxigenicity of

Staphylococcus aureus Isolated from Food Handlers during Hajj Season in

Saudi Arabia. Open Journal of Safety Science and Technology, 2011, 1, 75-78.

SAEED S. AL-GHAMDI. Occupational Exposure to Paints Causes

Impairment of Kidney Functions. Journal of Environmental Protection, 2011,

533-536.

Sami H. Hammadi, SAEED S. AL-GHAMDI, Ahmad I. Yassien, Saad D.

AL-Hassani Aspirin and Blood Glucose and Insulin Resistance. Open Journal

of Endocrine and Metabolic Diseases, 2012, 2, 16-26.

SAEED S. AL-GHAMDI et al. Prevalence and risk factors of

musculoskeletal pains among medical students in a malaysian medical college

(BMC Medical Education). BMC Research Notes, 2013, 6:244-252.

Ibrahim IAA, Shahzad N, Al-Joudi FS, Al-Ghamdi SS, Alshagga MA,

Hammodi NM. In Vitro and In Vivo Study of Effect of Α-Adrenergic Agonist-

Methyldopa on the Serum Biochemical Laboratory Findings. Clin Exp

Pharmacol 2013; 3 (4):2161-1459.

Shahzad N, Ahmad J, Khan W, Al-Ghamdi S.S, Ain MR, Ibrahim IAA,

Akhtar M, Khanam R. Interactions of atenolol with alprazolam/escitalopram

on anxiety, depression and oxidative stress. Pharmacology Biochemistry and

Behavior. (2014), 117:79-84.

Gulman Haider kHan, Mod Aqil, Krishna Kolappa Pillai, Md Afroz Ahmad,

Prem Kapur, Md Ruhal Ain, Saeed Saeed Al-Ghamdi, Naiyer Shahzad.

Therapeutic Adherence: A Prospective drug utilization study of oral

hypoglycaemic in patients with type2 diabetes mellitus. Asian Pac J Trop Dis.

4(1): 930-935.

Mohamed A. Afify, Naiyer Shahzad, Nazik Tawfik2, Ibrahim A. Ibrahim,

Zainularifeen, Abduljaleel, Wajahatullah Khan, Amal M. Mahfoz and Saeed

S. Al-Ghamdi; Evaluation of drug prescribing practices in private and general

hospitals in Makkah, Saudi Arabia African Journal of Pharmacy and

Pharmacology, 2015, Vol. 9(39), 966-973.

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Under per review:

Study the Effects of Some Immuno-Modulators and Anti-Inflammatory Drugs

on Experimental Epilepsy Model Induced by Li-Pilocarpine in Adult Male

Rats.

Baicalein, wound healing acceleration in rats through antioxidant defense and

Hsp70/Bax enhancement

Statements

1- Aerosols effects and managements, Ahlan Wasahalan, August 2006 (In Arabic

language).

2- Mercury types and poisoning and managements, Ahlan Wasahalan, March

2007 (In Arabic language).

3- Girls and cancer, Manar Al jame'ah (Umm Al Qura University), 111, January

2007 (In Arabic language)..

4- Drugs...remedies or poisons! (Umm Al Qura University), 112, February 2007

(In Arabic language)..

5- Together ..to eradicate Tuberculosis (Umm Al Qura University), 113, March

2007 (In Arabic language).

6- Ototoxicity, Medical knowledge journal, Ministry of interior, July, 2008.

ABSTRACTS

1- Title: Solvent induced activation of CYP2E1 causes proximal tubular

apoptosis by oxidative stress.

Names of Authors: Saeed S Al-Ghamdi, David A. Allen, Martin J.

Raftery, Muhammad M. Yaqoob

Name of the journal: Journal of American Society of Nephrology,

A4168 (2001)

2- Title: Hydrogen Peroxide-Induced Activation of CYP2E1 Mediates of

Proximal Tubular Injury.

Names of Authors: Saeed S Al-Ghamdi, David A. Allen, Martin J.

Raftery, Muhammad M. Yaqoob:

Name of the journal: Toxicol Lett 135, 2002

3- Title: Inhibition of cytochrome P4502E1 protects proximal tubular

cells against oxidant stress

Names of Authors: Saeed S Al-Ghamdi, Martin J. Raftery,

Muhammad M.

Name of the journal: Journal of Toxicology Clinical Toxicology, 41(4): 253,

(2003).

RESEARCH INTEREST

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1- Pharmacognosy

2- Clinical pharmacology

3- Biochemical pharmacology

4- Toxicology

PUBLIC SERVICES

Many educational lectures have been provided to the public including hospital staff,

school students regarding poisoning and management of intoxication

PATENTS

Single author

1- US8551187B1 (Herbal Hair Removal Composition).

http://www.google.com/patents/US8551187.

2- US20140242196A1 (Method of using Juniperus Phoenicea Fruit as a

Remedy for Snake Bites and Scorpion Stings).

http://www.google.com/patents/US20140242196

3- Docket No. 435423WO (Remedy For Sickle Cell Anemia).

4- Docket No. 427151WO (A Method And Composition Using Parsley

(Petroselinum Crispum) As A Natural Remedy For Diabetes Mellitus).

5- Docket No. 427163 WO (A Method And Composition Using Myrrh, Dill And

Peel Of Pomegranate As A Natural Remedy For Chronic Wounds).

6- Docket No. 427150 WO (A Method And A Composition Having Prophylactic

Activity Against Venoms And Toxins).

Co-author

1- New promising remedy for inflammatory skin diseases using the petroleum

ether extract of carrot seeds.

WORK AND MANAGEMENT EXPERIENCE

1- Medical technologist, Al-Nour Specialist Hospital, Makkah Al-

Mukarramah, Saudi Arabia, from 5-12-93 to 5-12-94. Nature of duty is

analysis of Patients biological samples in different laboratory areas.

2- Laboratory specialist, Toxicology and Forensic Chemistry Centre,

Makkah, Al-Mukarramah, Saudi Arabia, from 5-12-94 to 30-10-97. Nature

of duty is analysis of drug abuse samples, drug overdoses monitoring,

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alcohols and controlled materials analysis including Heroin, Cocaine,

Canabinol, Qat and Psychotic drugs.

3- Trainee in Toxicology Centre, Department of Pharmacology, School of

Pharmacy, University of London, U.K (October 1998 to May 2000).

4- Chairman, Saudi Students Club, London, From August 2000 to June

2001.

5- The organizer and chairman of the Association of Saudi Medical

technologists (ASMT) annual meeting held at Imperial College School of

Medicine (Hammersmith Hospital), London on the 1st September 2001.

6- Vice Dean and Head of Forensic Chemistry Department, Naif Arab

University For Security Sciences, Since August 2003.

7- Assistant professor and Dean Assistant at Forensic Sciences College, Naif

Arab University for Security Sciences, Riyadh, Aug. 2003 until June 2004.

8- Director of Toxicology Division, King Fahad National Guard Hospital,

Riyadh, Since January 2004 until August 2004 (LOCUM POSITION).

9- Chairman of the department of pharmacology and toxicology since June

2010 tell present.

10- Director of the medical research centre since December 2010 tell present.

11- Dean of health Sciences College in Qunfudah since December 2010 until

January 2014.

12- Dean of the college of medicine – Al-Qunfudah, December 2011 until

November 2013.

COMMITTEES

1- Member of Curriculum Committee, faculty of medicine, Umm Al-Qura

University.

2- Member of Safety and Security Committee, faculty of medicine, Umm Al-

Qura University.

3- Chairman of Scientific researches and societies committee, faculty of

medicine, Umm Al-Qura University.

4- Chairman of the committee of establishing Saudi Toxicology Society.

TEACHING EXPERIENCE

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My position in my home country, Saudi Arabia is a lecturer in toxicology. I

have been teaching undergraduate medical students for 2 years. I worked as an

assistant professor of toxicology at Naif Arab University For Security

Sciences (NAUSS) for one year (2003), teaching Environmental pollution and

Drugs controlling for both master and diploma students.

CURRENT POSITION

Consultant and Professor of Toxicology, Department of Pharmacology and

Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah Al

Mukarramah, since May 2004 to present.

MEMBERSHIP

1- The British Toxicology Society (BTS), since February 1999

2- European Society of Toxicology In Vitro (ESTIV), since January1999

3- American Society for Pharmacology and Experimental Therapeutic

(ASPET), since January 1999

4- International Society of Regulatory Toxicology and Pharmacology

(ISRTP), since February 1999

5- The EUROTOX, since November 1998

6- The Society of Toxicologic Pathologist (STP), since August 1998

7- Canadian Society for Pharmaceutical Sciences (CSPS), since August 1998

8- Saudi Pharmaceutical Society (SPS), since January 1996

9- American College of Toxicology (ACT), since June 1999

10- Society of Environmental Toxicology and Chemistry (SETAC), since

April 1999

11- Federation of American Societies for Experimental Biology (FASEB)

Since June 1999

12- Scandinavian Society of Cell Toxicology (SSCT), since May 2000

13- The Royal Society of Medicine, since Sept. 2000

14- Society of Toxicology (SOT), since February 2000

15- American Academy of Clinical Toxicology, September, 2000

16- Institute of Health Management, since August 2000

17- Associate of the Institute of Biomedical Sciences, since Sept. 2000

18- Member of the Institute of Biology, since March 2001

19- Centre for International Forensic Assistance (CIFA), UK, June 2002

20- The British Pharmacology Society (BPS), since August 2002

COURSES / CONFERENCES

1- Clinical Perspectives in Chemical dependency Held in Jeddah, Saudi Arabia

(November 21-22, 1993)

2- 50th

Anniversary Meeting of Renal Association Held in Cambridge, UK

(September 27-29, 2000)

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3- Annual congress of the British Society of Toxicology (BTS) held in Keele

University, (June 2001), UK

4- Annual meeting if the Institute of Health Management, held in Royal Free

Hospital on the 14th

June 2001, London

5- Polymer international conference held at the School of Pharmacy, University of

London, January 11-13, 2000

6- The 12th International Conference on Cytochrome P450: Biochemistry

Biophysics and Molecular Biology, which held in La Grande Motte (France) from

11 to 15 September 2001

7- The Renal Association Autumn meeting held in London (20-21 September

2001)

8- The American Nephrology Society (ASN) annual meeting held in San

Francisco (10-17 October 2001)

9- EUROTOX2002 meeting held in Budapest-Hungary (15-18 September

2002)

10- XXIII International Congress of the European Association of Poisons

Centres and Clinical Toxicologists held in Rome-Italy 20-23 May 2003

(17 points).

11- First conference of Arab Faculties of Medicine Society and First

Conference of Jordanian Faculties of Medicine held in Amman, Jordan 19-

22 April 2004.

12- New Trends in Pharmaceutical Services held in Jeddah, Saudi Arabia,

13-14 December 2005.

13- Second symposium of Forensic medicine held in Makkah, Saudi

Arabia, 2-3 May 2006.

14- The 44th

Scientific meeting of the international association of forensic

toxicologists, held in Ljubljana, Slovenia, 26 August – 1 September 2006.

15- Addiction and neurobiology First conference, held in Jeddah, Saudi

Arabia, 6-7 December 2006.

16- National symposium for health assurance grantee, Makkah, 15-16 May

2007.

17- Second symposium of the Forensic Toxicology, Jeddah, 4-5 June

2007.

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18- Genetic Toxicology International Meeting, Oxford, UK, 29th

July-3

August 2007.

19- Health care economic symposium, held in Makkah, 24t October 2007.

20- The 45th Congress of the European Societies of Toxicology, held in

Rhodes, Greece, 5-8 October 2008.

21- Conference of lands destruction in dried area, held in Kuwait, 8-14

March 2009.

22- The annual meeting of TIAFT, 23-27 August 2009, Athens, Greece.

23- SOT 2010 annual meeting, Utah, USA, 7-11 March 2010.

PRESENTATIONS

A poster entitled (The Cytotoxicity of Doxorubicin and its Conjugate,

PK1 on Prostate Cell Line). Presented in the international conference

held at the School of Pharmacy, University of London, January 11-13,

2000

Inhibition of cytochrome P4502E1 protects proximal tubular cells

against oxidant stress was accepted to be presented as a poster by The

12th International Conference on Cytochrome P450: Biochemistry

Biophysics and Molecular Biology, which will be held in La Grande

Motte (France) from 11 to 15 September 2001.

Aromatic hydrocarbon-induced apoptosis of proximal tubular cells:

role of oxidative stress and cytochrome P4502E1 was accepted to be

presented as 15 minutes talk by the Renal Association Autumn meeting

held in London (20-21 September 2001).

Solvent induced activation of cytochrome P4502E1 causes proximal

tubular apoptosis by oxidative stress was accepted by the American

Nephrology Society (ASN) for the annual meeting held in San

Francisco (10-17 October 2001) to be presented as a poster.

Hydrogen Peroxide-Induced Activation of CYP2E1 Mediates of

Proximal Tubular Injury was accepted by the EUROTOX2002 for the

annual meeting held in Budapest-Hungary (15-18 September 2002) to

be presented as a poster.

Mechanism of Solvent induced nephrotoxicity after chronic exposure

presented at The 44th

Scientific meeting of the international association

of forensic toxicologists, held in Ljubljana, Slovenia, 26 August – 1

September 2006.

16

Toxicology (Definition and applications) presented at The Second

Forensic Toxicology Symposium, Jeddah, 4-5 June 2007.

Poster entitled (Time and Dose Dependent Study Of Doxorubicin

Induced Du145 Cytotoxicity) at the Genetic Toxicology International

meeting held in Oxford, UK, 29th

July – 3 August 2007.

Presentation entitled "Protective Effect Of Nigella Sativa Against

Viral Hepatitis B" presented in The 45th Congress of the European

Societies of Toxicology, held in Rhodes, Greece, 5-8 October 2008.

Presentation entitled "Depleted Uranium and Its Negative Impact

On Environment" presented in the Conference of lands destruction in

dried area, held in Kuwait, 8-14 March 2009.

Presentation entitled "Hair As A Biological Indicator Of Drug Use,

Drug Abuse" presented in the The Annual Meeting of TIAFT, 23-27

August 2009, Athens, Greece.

Presentation entitled "The beneficial role of supplemental

antioxidants against cypermethrin toxicity" presented in the SOT

2010 annual meeting, Utah, USA, 7-11 March 2010..

BROADCASTING INTERVIEW

Television: Saudi TV Channel 1 , and Al Ekhbarryah TV Channel, about Drug of

abuse, on the 18/5/1428, Jeddah.

Newspapers: OKAZ and ALBELAD Saudi newspapers, interview about the drug of

abuse on the 19/5/1428, J3eddah.

LANGUAGES

Arabia, English

REFERENCES

11-Professor Magdi Yaqoob MD, PhD, FRCP

Head of Experimental Medicine and Nephrology Dept.

Consultant nephrologist,

59 St. Bartholomew Close, Dominion House,

London EC1A 7BE

Tel: 0207 601 8236

Fax: 0207 601 8238

17

e-mail: m.m.yaqoob@qmul.ac.uk

2- Prof. R J Flower PhD, DSc Head of Dept. Biochemical Pharmacology,

Charterhouse Square,

London EC1M 6BQ

Tel: 0207 882 6072

Fax: 0207 882 6076

E-mail: r.j.flower@qmw.ac.uk

3- Prof Alan R Boobis

Section on Clinical Pharmacology

Division of Medicine

Imperial College School of Medicine

Ducane Road

London W12 0NN, UK

Tel: +44 20 8383 3221

Fax: +44-20 8383 2066

Email: a.boobis@ic.ac.uk

4-Martin J Carrier PhD Reader of Experimental Therapeutics Department

The William Harvey Research Institute

Barts & the London School of Medicine & Dentistry

John Vane Science Centre

London EC1M 6BQ

Tel: +44 (0)20 7882 6079

Fax: +44 (0)20 7882 6037

e-mail: m.j.carrier@qmul.ac.uk

5- Ahmed A. H. Qassim PhD

P.O.Box 9223, Makkah, Saudi Arabia

Tel: 0096625563688

Fax: 0096625575065

E-mail: alshyma5@icc.net.sa

APPENDIX

Social activities

Chairman assistant, Saudi Students Club, London, August 2000-August

2001

Vice president of Saudi Students Clubs in UK and Ireland, September

2000-September 2001

18

Trainer of Umm Al-Qura University Students for Taekwondo (self

defence), June 1994-May1995

Vice president and treasurer of the Association of Saudi Medical

technologists (ASMT) May 2001-May 2002

Other qualifications

Computer Programming in Basic from Rocketfield Computer System,

U.K, January 1992

Subscription

1- Saudi Annals of Medicine, since June 1995

2-Human & Experimental Toxicology, since March 1998

3-Scientific America, since June December 1998

4-Toxicologic Pathologist, since January 1999

5-Drug Metabolism and Disposition, since January 1999

6-Pharmacological Review, since January 1999

7-Saudi Journal of Kidney Diseases and Transplantation, since June 2000

8-Journal of European toxicology and Chemistry, since April 1999

9-Saudi Pharmaceutical Journal, since January 1996

10-Regulatory Toxicology and Pharmacology, since December 1999

11- Journal of Toxicology Clinical Toxicology, Since June 2001

12- Saudi Laboratory Bulletin , since 2002