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Pharma OTC & Nutrition Market Situation MAT 2013Q2

Pharma Market OTC & Nutrition Situation MAT 2013 Q2

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Page 1: Pharma Market OTC & Nutrition Situation MAT 2013 Q2

Pharma OTC & Nutrition Market Situation MAT 2013Q2

Page 2: Pharma Market OTC & Nutrition Situation MAT 2013 Q2

2

2009 2010 2011 2012 20130

500

1,000

1,500

2,000

2,500

3,000

3,500

4,000

4,500

5,000

3,1193,453

3,816 4,187

4,755

Nutrition

OTC

ETH-ICAL

Sa

les

Va

lue

Tra

de

OK

U Y

EN

(ID

R1

0,5

83

,33

3,3

33

/OK

U Y

EN

)

42%

58% 61%

39%39%

61%

40%

+4%

+9%

+15%

+15% +11%

+13%

+11%

+11%+14%

39%

61%

+15%

+11%

+12%

60%

Exchange rate: Constant IDR10,583,333,333/OKU YENSource: IMS Plus 2013-Q2

Indonesia Pharmaceutical Market – MAT 2013Q2

• Indonesia is a big potential market for pharmaceutical industry, with total market size at OKU YEN 4,755 in MAT 2013Q2 • And the pharmaceutical market in Indonesia has grown rapidly at growth +12% in last year, driven by OTC sector growing +15% in

2013Q2 .• In overall the pharmaceutical market growth is outperforming economic growth (6%). • The market growth is expected to continue at the same rate for 2012-2015.

Page 3: Pharma Market OTC & Nutrition Situation MAT 2013 Q2

3

Top 20 Pharma Companies – Ethical & OTC

Rx (Ethical) OTC

Sales Trade

Market Share

Growth CAGR

Rank Status MAT 2013Q2

MAT 2013Q2

MAT 2013Q2

MAT 2013Q2

IND TOTAL ETHICAL 2,818 100% 11% 13%

1 KALBE GROUP LOCAL 395 14% 17% 15%

2 SANBE LOCAL 249 9% 16% 15%

3 DEXA MEDICA GROUP LOCAL 179 6% 16% 12%

4 NOVARTIS GROUP MNC 119 4% 10% 20%

5 SANOFI-AVENTIS GRP MNC 111 4% 8% 13%

6 FAHRENHEIT LOCAL 105 4% 17% 17%

7 PFIZER GROUP MNC 90 3% -1% 4%

8 KIMIA FARMA GROUP LOCAL 72 3% -4% 11%

9 MENSA GROUP LOCAL 71 3% 11% 13%

10 INDOFARMA LOCAL 69 2% 16% 11%

11 GLAXOSMITHKL GRP MNC 66 2% 16% 10%

12 BAYER INDONESIA MNC 60 2% 5% 9%

13 SOHO GROUP LOCAL 51 2% -3% 14%

14 OTSUKA GROUP LOCAL 51 2% 16% 9%

15 ACTAVIS MNC 50 2% 23% 28%

16 INTERBAT LOCAL 49 2% 9% 7%

17 DARYA-VARIA GROUP LOCAL 48 2% 7% 11%

18 B.INGELHEIM GROUP MNC 47 2% 20% 20%

19 PHAROS GROUP LOCAL 47 2% 5% 14%

20 ASTRAZENECA MNC 42 1% 12% 9%

Sales Trade

Market Share

Growth CAGR

Rank Status MAT 2013Q2

MAT 2013Q2

MAT 2013Q2

MAT 2013Q2

IND TOTAL OTC 1,892 100% 15% 11%

1 SOHO GROUP LOCAL 195 10% 25% 13%

2 KALBE GROUP LOCAL 179 9% -2% 2%

3 TEMPO GROUP LOCAL 159 8% 6% 8%

4 PHAROS GROUP LOCAL 137 7% 34% 26%

5 KONIMEX LOCAL 102 5% 11% 18%

6 DEXA MEDICA GROUP LOCAL 62 3% 10% 11%

7 DARYA-VARIA GROUP LOCAL 56 3% 17% 8%

8 GLAXOSMITHKL GRP MNC 54 3% 8% 14%

9 LAPI LOCAL 53 3% 79% 55%

10 NOVELL PHARM LOCAL 52 3% 30% 17%

11 BAYER INDONESIA MNC 40 2% 19% 0%

12 SANBE LOCAL 40 2% 7% -2%

13 INTERBAT LOCAL 34 2% 6% 8%

14 J&J MNC 31 2% -1% 9%

15 MERCK INDONESIA GP MNC 30 2% 7% 6%

16 MENSA GROUP LOCAL 28 1% -11% -6%

17 COMBIPHAR GROUP LOCAL 27 1% -3% 7%

18 B.INGELHEIM GROUP MNC 24 1% 12% 10%

19 MAHAKAM BETA FARMA LOCAL 24 1% 68% 45%

20 HISAMITSU PHARMA MNC 23 1% 38% 26%

Exchange rate: Constant IDR10,583,333,333/OKU YENSource: IMS Plus 2013-Q2

• Based on medication group, in average Top 5 companies in Rx and OTC are dominated by local companies, then only 3 MNCs are in the Top 10 in Ethical market.

• Both in Rx and OTC are perfect competition market. • Numbers of companies in Rx: 203 companies, in OTC: 186 companies.

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• At registration, drugs are categorised as one of the following: O (strictly controlled narcotics); G (prescription-only, obat keras); W (non-prescription, obat bebas terbatas, with warning label) and F (non-prescription, obat bebas).

– There is a sub-class of G referred to as G2. G2 products are pharmacy-bound, but can be sold over-the-counter if the pharmacist is sure that the customer needs the drug. These drugs cannot be advertised to the public.

• An alternative method of classification uses different coloured dots on packs:

– ‘Red dot’ products consist of G and G2 products.

– ‘Blue dot’ OTCs (equivalent to Class W) can be purchased without a ––prescription, but only through licensed drugstores and pharmacies. They have to display warning messages on packages and can be advertised to consumers.

– ‘Green dot’ OTCs (Class F drugs) are products available without prescription ––in any outlet e.g. drugstores, supermarkets, peddlers, cigarette kiosks and bookstores. There is no limit to the quantity of drug purchased and advertising to consumers is permitted.

OTC Market Description

Only Blue dot and Green dot drugs can be

advertised

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•As the pharmacist is commonly the first port of call, there is heavy reliance on over-the-counter (OTC) medicines or under-thecounter prescription drugs, and 30% of the population uses traditional jamu medicines.

•Growth in the OTC market is strong, and will be driven by the buoyant economy and expansion of outlets selling these products. Domestic companies in particular will continue to build up their non-Rx-bound businesses, especially in areas such as herbal medicine

•Vitamins, minerals and nutritional supplements are the largest non-Rx bound category in sales terms, followed by cough, cold and other respiratory remedies, and then pain relief.

•Herbal medicines, particularly modern herbal brands, which are encroaching into the market for conventional OTC medicines, are expected to become an important growth category. Leading local companies already have herbal lines and more local manufacturers especially those unable to meet new quality standards for prescription medicines, will branch out into herbals.

IMS Prognosis 2013 on OTC

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OTC & Nutrition Market

2009 2010 2011 2012 MAT 2013Q2

0.0

200.0

400.0

600.0

800.0

1,000.0

1,200.0

1,400.0

1,600.0

1,800.0

2,000.0

114.2 129.2 141.2 112.3 45.2

1,260.2 1,309.9 1,432.4

1,644.1 1,892.0 OTC

Nutrition

Sales in OKU YEN Share (%) Growth YoY (%) CAGR2009 2010 2011 2012 MAT 2013 Q2 2009 2010 2011 2012 MAT 2013 Q2 2010 2011 2012 MAT 2013 Q209-'13

OTC + Nutrition 1,374.4 1,439.1 1,573.7 1,756.3 1,937.3 100.0% 100.0% 100.0% 100.0% 100.0% 4.7% 9.3% 11.6% 10.3% 9.0%Lifestyle 339.4 334.8 338.5 350.5 363.9 24.7% 23.3% 21.5% 20.0% 18.8% -1.4% 1.1% 3.5% 3.8% 1.8%Herbal 109.6 109.4 123.7 166.2 215.8 8.0% 7.6% 7.9% 9.5% 11.1% -0.2% 13.0% 34.4% 29.9% 18.5%Skin Vitamin 42.9 51.6 53.2 63.4 101.5 3.1% 3.6% 3.4% 3.6% 5.2% 20.2% 3.1% 19.2% 60.1% 24.0%Digestive / GI 47.6 44.9 48.0 59.8 70.4 3.5% 3.1% 3.0% 3.4% 3.6% -5.7% 6.9% 24.7% 17.7% 10.3%Respi 34.2 38.6 45.3 51.9 52.3 2.5% 2.7% 2.9% 3.0% 2.7% 12.9% 17.3% 14.5% 0.8% 11.2%Laxative 33.2 32.3 36.6 44.2 51.7 2.4% 2.2% 2.3% 2.5% 2.7% -2.5% 13.1% 20.7% 17.1% 11.7%Memory 6.0 8.2 11.3 15.6 17.5 0.4% 0.6% 0.7% 0.9% 0.9% 36.7% 38.4% 38.3% 12.0% 30.9%Others 761.5 819.4 917.1 1,004.7 1,064.1 55.4% 56.9% 58.3% 57.2% 54.9% 7.6% 11.9% 9.6% 5.9% 8.7%

Lifestyle19%

Skin Vi-tamin5%

Diges-tive / GI4%

Laxa-tive3%

Memory1%

Herbal11%

Others56%

MAT 2013Q2 $ Share (%)

Based on our own market category definition, Lifestyle Product (incl Multi Vitamin and Tonic) is the leading category is at 18.8% of share with +3.8% growth. The other Top category are Herbal and Skin Vitamin which driving the market growth.

+4.7%+9.4%

+11.6%

+10.3%

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OTC – Lifestyle Market (1)

Lifestyle market is dominated and driven by Vitamin subcategory, but still below overall OTC growth. Zooming in, Multivitamins are the top 3 subcategory for Vitamin. Oppositely, Vitamin-Kid suffered negative growth YoY - last year.

Sales in OKU YEN Share (%) Growth YoY (%) CAGRSUB-CATEGORY MAT 2013 Q2 MAT 2013 Q2 MAT 2013 Q2 '09-'13

ATC IV TOTAL OTC - LIFESTYLE 363.9 100.0% 3.8% 1.8% A11A4 MVIT + MIN OTHERS Lifestyle - Vitamin 59.3 16.3% 12.3% 6.7% A11B4 MVIT W/O MIN OTHERS Lifestyle - Vitamin 45.4 12.5% 13.0% 0.4% A11D4 VIT.B1+VIT.B6 &/OR B12 Lifestyle - Vitamin 35.6 9.8% 4.2% 5.9% A11G2 VITAMIN C COMBINATIONS Lifestyle - Vitamin 29.7 8.2% 22.5% 6.0% A11E3 VITAMIN B COMPLEX OTHERS Lifestyle - Vitamin 28.1 7.7% -4.0% 3.2% A11G1 VITAMIN C PLAIN Lifestyle - Vitamin 20.3 5.6% -1.8% 1.6% A11E2 VITAMIN B COMPLEX + VIT C Lifestyle - Vitamin 14.1 3.9% 11.1% 6.3% A11D9 OTHER VITAMIN B1 COMBS Lifestyle - Vitamin 11.2 3.1% 5.7% 11.2% A11X9 ALL OTHER VITAMINS Lifestyle - Vitamin 9.1 2.5% 6.7% 37.6% A11D3 VITAMIN B1 PLAIN Lifestyle - Vitamin 3.0 0.8% 35.7% 6.2% A11E1 VITAMIN B COMPLEX PLAIN Lifestyle - Vitamin 2.7 0.7% 6.3% -3.3% A11X2 VIT B6(PYRIDOXINE) PLAIN Lifestyle - Vitamin 0.7 0.2% 42.9% 6.9% A11F0 VITAMIN B12 PLAIN Lifestyle - Vitamin 0.5 0.1% 97.1% 16.9%

Lifestyle - Vitamin 259.8 71.4% 8.8% 5.1% A13A2 ALL OTHER TONICS Lifestyle - Tonic 58.7 16.1% -10.9% -8.7%

Lifestyle - Tonic 58.7 16.1% -10.9% -8.7% S01M0 EYE TONICS&EYE VITAMINS Lifestyle - Eye 23.2 6.4% 2.2% 0.4%

Lifestyle - Eye 23.2 6.4% 2.2% 0.4% A11B2 MVIT W/O MIN PAEDIATRIC Lifestyle - Kid 10.1 2.8% -2.4% 2.8% A11C3 VITAMIN A & D COMBS Lifestyle - Kid 9.4 2.6% -4.7% 7.4% A11A2 MVIT + MIN PAEDIATRIC Lifestyle - Kid 2.7 0.7% -10.9% -0.5%

Lifestyle - Kid 22.2 6.1% -4.5% 4.2%

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OTC – Lifestyle Market (2)

Lifestyle - Vi-tamin71%

Lifestyle - Tonic16%

Life-style - Eye6%

Life-style -

Kid6%

MAT 2013 Q2

Sales in OKU YEN Share (%) Growth YoY (%) CAGRSub-Category MAT 2013 Q2 MAT 2013 Q2 MAT 2013 Q2 '09-'13Lifestyle - Vitamin 259.8 71.4% 8.8% 5.1%Lifestyle - Tonic 58.7 16.1% -10.9% -8.7%Lifestyle - Eye 23.2 6.4% 2.2% 0.4%Lifestyle - Kid 22.2 6.1% -4.5% 4.2%

Vit B ComplexHemaviton (TFC)OKU YEN 8.9CAGR +3.6%

Vit B1+B6+B16Neurobion (MCK)OKU YEN 14.3CAGR +3.0 %

Vit C CombinationCerebrovit X-Cel (TCN)OKU YEN 15.9CAGR +6.9%

Multivitamin KidCurcuma Plus (SHO)OKU YEN 9.6CAGR -7.1%

Vitamin C PlainVitacimin (TAK)OKU YEN 7.3CAGR +5.5%

Popular Products

Other Vit B+CombCerebrovit X-Cel (KLB)OKU YEN 2.0CAGR +10.7%

Vitamin products are mostly registered as food supplement product at BPOM (local FDA). This subcategory is heavily advertised, and in average the product advertisement show the benefit is to increase stamina, boost imunity and relieve muscle/nerves stiffness. The pacakging range from capsules, chewable/nonchewable tablet, to RTD . The Vitamin products mostly are dominated by Local manufacturers, even though there are some MNC are competing in this category as well.

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OTC – Herbal

Herbal - Others87%

Herbal - Lipo8%

Herbal - Anti Atheroma

2%

Herbal - BPH1%

Herbal - Hypno1%

Herbal - Appetite

0%

Herbal - An-tidepressant

0%

MAT 2013 Q2Popular Products

Sales in OKU YEN Share (%) Growth YoY (%) CAGRSUB-CATEGORY MAT 2013 Q2 MAT 2013 Q2 MAT 2013 Q2 '09-'13

ATC IV TOTAL OTC - HERBAL 215.8 100.0% 29.9% 18.5% V03X0 ALL OTH.THERAPEUTIC PRDS Herbal - Others 186.9 86.6% 30.4% 19.6% A05B0 HEPAT PROTECT-LIPOTROPICS Herbal - Lipo 18.2 8.4% 13.2% 10.0% C10B0 ANTI-ATHEROMA NATRL ORIG Herbal - Anti Atheroma 4.9 2.3% 149.1% 46.9% G04C9 BPH PRODUCTS OTHER Herbal - BPH 3.1 1.5% 20.2% 9.5% N05B5 HERB HYPNOTICS/SEDATIVES Herbal - Hypno 1.9 0.9% 67.9% 6.3% A15A0 APPETITE STIMULANTS Herbal - Appetite 0.8 0.4% -29.7% -4.9% N06A2 ANTIDEPRESSANTS, HERBALS Herbal - Antidepressant 0.0 0.0% -14.3% -10.1%

Herb HypnoticLelap (SHO)OKU YEN 1.9CAGR +6.5%

All Oth Thera ProdImboot (SHO)OKU YEN 35.5CAGR +18.7%

Hepa Protect-LipoBio Curliv (SHO)OKU YEN 3.4CAGR +90.5%

BPH ProductBatuin (KM7)OKU YEN 2.2CAGR +12.5%

Herbal category recorded a very high growth at +29.9% yoy and 5 yrs CAGR at +18.5%, this category has been the raising category over the past years. Many of local companies are expanding to launch Herbal products. The usage of Herbal products range from boosting stamina, relieving sleep disorder, and hormonal BPH product. The existing products have been showing positive growth due to affordable price, wide availability, heavy advertisment and high acceptability by most Indonesian. All Herbal products are manufactured and registered by Local products, as their original product development.

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OTC – Skin Vitamin Market

Vitamin E PlainNature-E (D.V)OKU YEN 11.8CAGR +14.8%

Vitamin E PlainEver E (KOX)OKU YEN 9.8CAGR +178.8%

Other DermatoNourish Skin (P-I)OKU YEN 43.6CAGR +14.2%

Other DermatoDermatix (T5F)OKU YEN 5.7Growth ’12-13 ,+58.2%

Popular Products in Skin Category

Only 2 subcategories: Dermatological and Vitamin E plain, even though both base ingredients are the same (Vitamin E). The growth has been tremendous at +60.1% yoy and 5 yrs CAGR at +24.0%. Some of the products are registered as food supplement at BPOM – except for topical product. The benefit as promoted, is to keep skin healthy, rejuvenate skin to be younger looks, and increase skin moist through internal system. The packaging range from tablet to topikal cream – some topikal product is promoted to erase skin scars or sun burn (i.e Dermatix). One of the biggest product is Nourish Skin from Pharos. It targets young-adult female as to keep their skin shiny and healthy. It’s heavily advertised and available at the top shelf display in all Pharos’ own retail pharmacy chain – Century.

Sales in OKU YEN Share (%) Growth YoY (%) CAGRSUB-CATEGORY MAT 2013 Q2 MAT 2013 Q2 MAT 2013 Q2 '09-'13

ATC IV TOTAL OTC - SKIN 101.5 100.0% 60.1% 24.0% D11A0 OTHER DERMATOLOGICALS Skin - Others 72.8 71.7% 75.3% 22.9% A11X3 VITAMIN E PLAIN Skin - Vit E 28.7 28.3% 31.2% 27.2%

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OTC – Digestive / GI Market

Digestive / GI - Stomato

4%

Digestive / GI - Anti-flatulent

3%Digestive /

GI - An-tiulcerant

3%Digestive / GI - Stom-ach Disord

6%

Digestive / GI - Anti Diarrhea

73%

Digestive / GI - Enzym11%

MAT 2013 Q2Popular Products

Antidiarr Micro OrganiLacto B (NLL)OKU YEN 9.9CAGR +11.8%

Antidiarr AdsorbentNeo Entrostop (KLB)OKU YEN 7.5CAGR +6.3%

GI digestive market is mostly dominated by Anti-Diarrhea products. The Anti-Diarrhea subcategory is one of the most promising subcategory due to high incidence rate in Indonesia. There are two product base ingredients: natural (probiotic & herbal) & chemical. Probiotic is widely used for toddlers diarrhea case, as it’s safe and convenience to be consumed (in powder or liquid form). However, most of the Probiotic pricing is not cheap – in average. The cheaper base ingredient is Attapulgite, a herbal based, and also widely popular among rural population, mostly sold in 4 tablets sachet and widely available at street stalls.

Sales in OKU YEN Share (%) Growth YoY (%) CAGRSUB-CATEGORY MAT 2013 Q2 MAT 2013 Q2 MAT 2013 Q2 '09-'13

ATC IV TOTAL OTC - DIGESTIVE / GI 70.4 100.0% 60.1% 24.0% A07F0 ANTIDIARR MICRO-ORGANISMS Digestive / GI - Anti Diarrhea 25.3 35.9% 50.1% 26.2% A07B0 INTEST ADSORBENT ANTIDIA Digestive / GI - Anti Diarrhea 20.9 29.7% 2.2% 6.1% A09A0 DIGESTIVES INC.ENZYMES Digestive / GI - Enzym 7.5 10.6% 7.4% 2.6% A07X0 OTHER ANTIDIARRHOEALS Digestive / GI - Anti Diarrhea 5.0 7.1% -15.0% 0.6% A02C0 OTH STOMACH DISORDER PREP Digestive / GI - Stomach Disord 4.5 6.4% 22.4% 9.4% A01A0 STOMATOLOGICALS Digestive / GI - Stomato 2.9 4.1% 54.7% 0.8% A02B9 ALL OTHER ANTIULCERANTS Digestive / GI - Antiulcerant 1.6 2.3% -19.0% -3.5% A02A2 PLAIN ANTIFLATULENTS Digestive / GI - Antiflatulent 1.5 2.1% 34.7% 10.6% A07A0 ANTI-INFECTIVE ANTIDIARR Digestive / GI - Anti Diarrhea 0.5 0.7% -5.4% 22.3% A02A7 ANTIFLATULENTS + OTHERS Digestive / GI - Antiflatulent 0.5 0.7% 428.0% #DIV/0! A02B1 H2 ANTAGONISTS Digestive / GI - Antiulcerant 0.3 0.4% -26.2% -10.5%

Anti diarrhe OtherDiapet (SHO)OKU YEN 4.3CAGR -3.3%

Stomach DisorderFucoidan (SHO)OKU YEN 3.3CAGR +6.5%

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OTC - Respiratory

Respi - Asthma

27%

Respi - Cough & Cold24%

Respi - Alergic35%

Respi - Nasal14%

MAT 2013 Q2

Sales in OKU YEN Share (%) Growth YoY (%) CAGRSUB-CATEGORY MAT 2013 Q2 MAT 2013 Q2 MAT 2013 Q2 '09-'13

ATC IV TOTAL OTC - RESPIRATORY 52.3 100.0% 0.8% 11.2% R04A0 CHEST RUBS & INHALANTS Respi - Asthma 11.4 21.9% 46.1% 15.9% R05D1 ANTITUSSIVES PLAIN Respi - Antitusive 10.1 19.4% -16.6% 18.0% R05F0 OTHER COUGH & COLD PREPS Respi - Cough & Cold 10.1 19.2% 42.0% 26.1% R03B2 XANTHINES,SYSTEMIC Respi - Alergic 7.7 14.8% -40.4% -1.4% R02A0 PHARYNGEAL PREPARATIONS Respi - Alergic 7.1 13.5% 7.2% 4.6% R01B0 SYSTEMIC NASAL PREPS Respi - Nasal 3.6 7.0% 4.5% 2.4% R01A7 NASAL DECONGESTANTS Respi - Nasal 1.3 2.4% 17.0% 7.4% R01A9 OTH TOPICAL NASAL PREPS Respi - Nasal 0.9 1.8% 34.1% 27.6% R03X2 ALL OTH A-AS & COPD, SYS Respi - Asthma 0.0 0.0% 4800.5% -14.8%

Popular Products

The growth of Respiratory category is lower than others, at +0.8% yoy, even though its 5 yrs CAGR is at +11.2%. The product pack ranges from Tablets, Topikal, and Drops and Syrup. The top biggest subcategories are Allergic, Asthma and Cough & Cold. This category, in average, is promoted through electronic media; TV and radio, and printed media. Many reason of its slowing down sales value due to decreasing spending on advertising from local companies. However this category is not seasonal, compared to European countries, the incidence rate is almost stable over the seasons in Indonesia.

Chest Rubs & InhalantTranspulmin (T5F)OKU YEN 4.4CAGR +12.5%

Other Cough & ColdLaserin (MEC)OKU YEN 7.5CAGR +32.2%

Xanthines, systemicNeo Napacin (KOX)OKU YEN 4.0CAGR -12.5%

Systemic Nasal PrepsWoods Pepermint (SKA)OKU YEN 3.2CAGR +9.4%

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OTC – Laxative

Sales in OKU YEN Share (%) Growth YoY (%) CAGRSUB-CATEGORY MAT 2013 Q2 MAT 2013 Q2 MAT 2013 Q2 '09-'13

ATC IV TOTAL OTC - LAXATIVE 51.7 100.0% 17.1% 11.7% A06A2 STIMULANT LAXATIVES Laxative - General 14.5 28.0% 15.3% 5.3% V06A0 SLIMMING PREPARATIONS Laxative - Slimming 13.4 25.9% 1.0% 7.6% A06A4 LAXATIVE ENEMAS Laxative - General 13.2 25.5% 28.0% 26.4% A06A3 BULK-FORMING LAXATIVES Laxative - General 6.5 12.6% 38.5% 14.6% A06A6 OSMOTIC LAXATIVES Laxative - Ethical 2.7 5.2% 15.5% 11.3% V07A0 OTHER-NON-THERAPEUTIC Laxative - Weight Loss 1.1 2.1% 43.4% 11.9% A06A1 FAECAL SOFTENING LAXATIV Laxative - General 0.4 0.7% 38.4% 70.0%

Laxative - General

67%

Laxative - Slimming

26%

Laxative - Ethical5%

Laxative - Weight Loss2%

MAT 2013 Q2

Popular Products

Laxative category grew at +17.1% yoy and 5 yrs CAGR at +11.7%.. The packs range from tablets to enemas. There is one heavily advertised product; Laxing by Soho, is a herbal based product, the latet CAGR is only at +0.6%.

StimulantDulcolax (B.I)OKU YEN 7.6CAGR +12.1%

StimulantLaxing (SHO)OKU YEN 6.6CAGR +0.6%

EnemaMicrolax (P-I)OKU YEN 12.9CAGR +27.0%

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OTC – Memory Preserve

Memory - Nootropic

45%

Memory - Cerebral

43%

Memory - Neurotonic

13%

MAT 2013 Q2Popular Products

NootropicNeulin (FPP)OKU YEN 6.8CAGR +72.9%

Sales in OKU YEN Share (%) Growth YoY (%) CAGRSUB-CATEGORY MAT 2013 Q2 MAT 2013 Q2 MAT 2013 Q2 '09-'13

ATC IV TOTAL OTC - MEMORY 17.51 100.0% 12.0% 30.9% N06D0 NOOTROPICS Memory - Nootropic 7.81 44.6% 18.7% 80.0% C04A1 CEREB.&PERI.VASOTH.EXC CA Memory - Cerebral 7.47 42.7% 13.4% 19.4% N06E0 NEUROTONIC & MISCELL Memory - Neurotonic 2.22 12.7% -9.7% 9.4%

Memory preserve category is smaller than other category in terms of sales value, but with high growth at +12.0% yoy and 5 yrs CAGR at 30.9%. Most of the products are promoted to increase memory and avoid ageing memory capacity.

CerebralSoholin (SHO)OKU YEN 2.6CAGR +64.2%

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Toddler10%

Kids10%

Teens10%

Teens adult9%Young

adult8%

Early jobber9%

Young Parent

8%

Par-ent-hood8%

Mature18%

Ageing well11%

Age Group Population

Source: sp2010.bps.go.id

Indonesian population per 2010 national census grew at 1.1% YoY. The population pyramid has shown a shift to a bigger young to middle age group – which resulted to the increasing productive age group between 24 to 54 y.o. The split between Male:Female is almost equal, except a slightly higher in Female Ageing Well group

Population % based on total age group % based on GenderGrouping Age Range # of Population Male Female ALL Male Female ALLToddler 0-4 22,678,702 10% 9% 10% 51% 49% 100%Kids 5-9 23,253,480 10% 10% 10% 51% 49% 100%Teens 10-14 22,671,081 10% 9% 10% 51% 49% 100%Teens adult 15-19 20,880,734 9% 9% 9% 51% 49% 100%Young adult 20-24 19,891,633 8% 8% 8% 50% 50% 100%Early jobber 25-29 21,310,443 9% 9% 9% 50% 50% 100%Young Parent 30-34 19,830,685 8% 8% 8% 50% 50% 100%Parenthood 35-39 18,505,131 8% 8% 8% 50% 50% 100%Mature 40-54 42,127,155 18% 18% 18% 50% 50% 100%Ageing well 55+ 26,492,282 11% 12% 11% 48% 52% 100%Total 237,641,326 100% 100% 100% 50% 50% 100%

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Indonesia Socio Economic Class - Nielsen & BCG reportNielsen, the leading global market data provider company, publishes yearly consumer segmentations, called Socio Economic Class (SEC) and the single measure/ criteria is heavily based on routine Monthly Household Expenditure (MHE). It’s widely used by consumer goods company or any marketer which targeting consumer/ patient base. It shows the level of economic buying power, from the lowest E class (those who spends MHE below IDR 700K per month to the highest A class (> IDR 3mio per month). From the past 3 years consecutive data below, it tells us that Indonesian middle economic classes (AtoC1) are increasing at +6% average, correlates to the economic growth at +6% yoy. This is also aligned with the latest Boston Consulting Group’s (BCG) report and World Bank’s report on Indonesian middle class

2010 2011 2012Year

8% 8% 14%

18% 16%

25%

23% 23%

28%25% 27%

22%17% 14%

8%9% 12%3%

E IDR < 700.000

D IDR 700.001 - 1.000.000

C2 IDR 1.000.001 - 1.500.000

C1 IDR 1.500.001 - 2.000.000

B IDR 2.000.001 - 3.000.000

A IDR > 3.000.000

+6%

+9%

+5%

Nielsen’s SESBCG’s Report

World Bank’s Report – from the

economist.com