PAEDIATRIC

ANTIDIARRHOEAL

By,

Kamal Krishna Singh

1

7th April 2015

Presentation map

Introduction

Market Analysis

Prescription Analysis

Doctors Desk

Retailer Corner

Interpretation

2

Introduction3

Indian Pharmaceutical Market is occupied with more than 1850

brand of Antidiarrhoeal products.

44 different types of combination & 17 different type of plain

(Single API).

82% Brands Combination & 18% Brands Plain Formulations.

91% from Domestic & 9% from MNC.

Formulations : 4% Injectables, 24% Liquid and 72% Solid.

In liquid formulation 30 ml is the most available quantity (71%)

followed by 60 ml (21%).

Market Analysis

All India Antidiarrhoeal Market (IMS: Oct13)

Particulates Value (Crs) Present Approximation

Sum of MAT OCT 13 1518.8 1550

Sum of MAT GR OCT 13 1.2% 1.5%

4

TOP 5 ANTIDIARRHOEAL BRANDS IN VALUE

BRAND MOLECULES COMPANY VAL OCT 13 GROWTH(%)

O2 OFLOXACIN + ORNIDAZOLE MEDLEY PHARMACEUTICALS 37 1.66

METROGYL METRONIDAZOLE JB CHEMICALS 30 24.34

ZENFLOX OZ OFLOXACIN + ORNIDAZOLE MANKIND PHARMACEUTICALS LTD. 28 -5.47

NORFLOX TZTINIDAZOLE +

NORFLOXACIN + LACTOBACILLUS

CIPLA LTD. 27 -6.66

MESACOL MESALAZINE SUN PHARMACEUTICAL INDUSTRIES LTD 20 14.28

Market Analysis5

ANTIDIARRHOEAL BRANDS (ABOVE 10 CRS) WITH MAXIMUM GROWTH

BRAND MOLECULES COMPANY VAL OCT 13 (Crs) GROWTH(%)

RIFAGUT RIFAXIMIN SUN PHARMACEUTICAL INDUSTRIES LTD 20 50

XYLISTIN COLISTINE CIPLA LTD. 15 48

ELDOPER LOPERAMIDE MICRO LABS LTD 12 30

SAAZ SULFASALAZINE IPCA LABORATORIES PVT LTD. 10 25

METROGYL METRONIDAZOLE JB CHEMICALS 30 24

ANTIDIARRHOEAL COMBINATION WITH MAXIMUM NO. OF PLAYERS

COMBINATION BRAND (LEADER) COMPANY NO. OF PLAYERVAL OCT 13

(Crs)

OFLOXACIN + ORNIDAZOLE O2 MEDLEY PHARMACEUTICALS 394 37

CIPROFLOXACIN + TINIDAZOLE CIPLOX TZ CIPLA LTD. 209 20

PROBIOTIC MICROBES ENTEROGERMINA SANOFI 185 34

OFLOXACIN + TINIDAZOLE OFLOX TZ CIPLA LTD. 127 1

NORFLOXACIN+TINIDAZOLE TINIBA ZYDUS 102 1

Prescription Analysis (Paediatrician)6

4835

5 3 2 2

ZIN

C

PR

EP

AR

AT

ION

/DT

/ L

IQ(L

)

RA

CE

CA

DO

TR

IL

SA

CH

ET

( L

)

RIF

AX

IMIN

(L

)

RA

CE

CA

DO

TR

IL (

KT

/ D

T )

RA

CE

CA

DO

TR

IL+

LY

OP

HY

SA

CC

HA

(L)

Oth

ers

Antidiarrhoeal Oral Liquid Vs % of Prescription

C marc-feb2015

For academic purpose

only

Prescription Analysis (Paediatrician) 7

33

116 5 4

40

Z &

D D

RO

PS

[D

RL

-

WIN

TU

RA

]

Z &

D S

YR

[D

RL

-

WIN

TU

RA

]

RA

CIG

YL

SB

SA

CH

ET

[MA

NK

IND

-DIS

C]

RA

LO

P S

AC

HE

T /

SY

R [

SA

LU

D C

AR

E

]

RA

CIG

YL

SA

CH

ET

[MA

NK

IND

-DIS

C]

Oth

ers

Different Antidiarrhoeal Oral Liquid Brands Vs % Prescription

C marc-feb2015

For academic purpose

only

Prescription Analysis (Paediatrician) 8

56

31

5 3 2 4

RA

CE

CA

DO

TR

IL

(S)

LO

PE

RA

MID

E (

S)

RIF

AX

IMIN

(S

)

PE

C.,K

AO

.WIT

H

AN

TI-

DIA

R.C

B.(

S)

FU

RA

ZO

LID

ON

& O

TH

ER

S (

S)

Oth

ers

Antidiarrhoeal Oral Solid Vs % of Prescription

C marc-feb2015

For academic purpose

only

Prescription Analysis (Paediatrician) 9

2311 10 8 8

41

RA

CIG

YL

KID

TA

B

[MA

NK

IND

-DIS

C]

ZE

DO

TT

CA

PS

[T

PL

- V

IST

A ]

RID

OL

TA

B [

GU

FIC

]

AN

DIA

L T

AB

[VE

RIT

AZ

-VE

RI]

EN

UF

F C

AP

S

[HE

TE

RO

-PH

]

Oth

ers

Different Antidiarrhoeal Oral Solid Brands Vs % Prescription

C marc-feb2015

For academic purpose

only

Doctors Desk10

Antidiarrhoeal treatment in children depends upon several factors.

Age

Body weight

Severity

Type of infection

Others (ADR, suffering with other disease etc)

Antidiarrhoeal Oral Liquid: Issues -unpalatable, bitter taste, constipation &

dosage accuracy.

Most GP does not treat and refer to Paediatrician if the child age is below 2-3

years.

Safety & efficacy are the major concern while prescribing a brand.

Mostly go with brand of reputed company to avoid risk.

Retailer Corner11

Most of the prescription for Antidiarrhoeal formulation come

from GP if the age of patients is above 3-4 years followed by

Paediatrician if the age is below 2-3 years.

Top selling formulation are Z & D Drops of DRL and O2 of

MEDLEY PHARMACEUTICALS in Antidiarrhoeal

formulations.

Average Selling of O2 Sups is 15-16 bottle PM.

Interpretation12

Growth of Antidiarrhoeal Oral Solid (1.90%) is higher than Oral

Liquid (1.40%), however the market size of Antidiarrhoeal Oral

Liquid is 4 times higher than that of Solid; So focus should be

on Liquid Formulation.

Demand of Antidiarrhoeal oral liquid or solid is highest during

march to june months followed by july to oct months.

Maximum prescribed Antidiarrhoeal formulations are Z & D

Drops, O2 Sups and Racigyl kid tab.

Promotion of Antidiarrhoeal high end product (serious) should

be targeted to Paediatrician only.

13