12. Response of your Joint to Arthritis Damage = pain
13. Your Bodys Response to Damage REPAIR = RELIEF
14. Joint Homeostasis Damage Repair
15. Summary damage pain repair relief
16. Quiz time A meniscus tear
17. How do we reduce damage?
18. Items causing damage
19. Weight Control
20. Weight Control tips
21. Bad Exercise/ Activity
22. Good Exercises
23. Bow legged Correction
24. Correcting the bow
25. Shoes make a difference
26. What is proper shoe wear ? PushTest-
27. What is a proper shoe? TwistTest NOT
28. What is a proper shoe? SqueezeTest
29. Nutritional Deficiencies
30. Correct Nutritional Deficiencies
31. Glucosamine Yes or No?
32. Summary
33. QuizTime is a
34. Turning onThe Repair of your joint
35. Gel Injections
36. Gel Injections
37. Gel Injections
38. Gel Injections
39. GelInjections
40. Summary of Hyaluronic Acid Injections
41. Quiz time
42. Steroid Injections
43. Steroid Injection
44. Steroid Injections temporary
45. Steroid Injections
46. QuizTime average
47. Summary of Steroids
48. Platelet Rich Plasma (PRP)
49. Platelet Rich Plasma Growth Factors They act like
fertilizer for your joints.
50. Platelet Rich Plasma (PRP) Safety Efficacy Efficacy
*Teitze, DC et al. entitled The effects of platelet rich plasma in
the treatment of large-joint osteoarthritis: a systemic review.
(Physiology and Sports Medicine 2014, May;42(2) 27-37)
51. Platelet Rich Plasma Duration
52. Platelet Rich Plasma for soft tissue issues! tendonitis
bursitis sprains or tears
53. Platelet Rich Plasma
54. Summary of PRP
55. QuizTime
56. Plasma Proteins Proteins
57. Plasma Proteins A2M IRAP *FrizzieroA, Autolgous conditioned
serum for the treatment of osteoarthritis and other possible
applications in musculoskeletal disorders. Br Med Bull. 2013: 105:
169-84.
58. Plasma Protein IRAP *Attur M, Plasma levels of
interleukin-1 receptor antagonist (IL1Ra) predict radiographic
progression of symptomatic knee osteoarthritis. Osteoarthritis
Cartilage. 2015 Nov;23(11):1915-24 IRAP is used by many race horses
to improve performances.
59. Benefits of Blocking Interluekin-1 ***Dinarello, CA et al,
Treating inflammation by blocking interleukin-1 in humans; Semin
Immunol. 2013 Dec 15 25(6) 469-84.
60. Plasma Protein a2M Weng S et al, Identification of
a2-macroglobulin as a master inhibitor of cartilage- degrading
factors that attenuates the progression of post traumatic
osteoarthritis, Arthritis Rheumatol. 2014 Jul: 66(7) 1843-53
61. A2M
62. PRP Plus
63. PRP Plus
64. Bone Marrow Concentrate Stem Cells
65. Bone Marrow Concentrate Stem Cells 300% 90%
66. Bone Marrow Concentrate Stem Cell
67. Bone Marrow Concentrate Stem Cell platelet rich
plasma.
68. Bone Marrow Concentrate Safety Safety- *World J
Gastroenterol. 2014 Oct 14;20(38):14051-7 **Lalu MM et al, Safety
of Cell Therapy with Mesenchymal Stromal Cells (SafeCell): A
systemic Review and Metanalysis of Clinical Trials. PLoS One. 2012
Oct 25 7(10) e47559. ***Herniguo P et al, Cancer risk is not
increased in patients treated for orthopedic disesases with
autologous bone marrow concentrate. J Bone Joint Surg Am, 2013 Dec
18: 95(24) 2215-21
69. Bone Marrow Concentrate Stem Cell Convenience
70. Bone Marrow Concentrate Stem Cell
71. Bone Marrow Concentrate Stem Cell Efficacy (Does itWork?)
one injection more two surgeries. *Ref- Autologous bone
marrow-derived mesenchymal stem cells versus autologous chondrocyte
implantation: an observational cohort study. Nejadnik H., American
Journal of Sports Medicine 2010 Jun;38(6):1110
72. Stem Cells improve outcomes of common surgeries improve
**Wong, KL. et al Injectable cultured bone marrow-derived
mesenchymal stem cells in varus knees with cartilage defects
undergoing high tibial osteotomy: a prospective, randomized
controlled clinical trial with 2 years' follow-up. Arthroscopy 2013
Dec;29(12):2020-8 ***KohYG et al, Adipose Derived Mesenchymal
StemCells with Microfracture vs. Microfracture Alone: 2-Year Follow
up of a Prospective RandomizedTrial, Arthroscopy, 2016 Jan, 32(1)
97- 109
73. Bone Marrow Concentrate Stem Cell For Hips Hernigou, P, et
al, Cell Therapy of hip necrosis with autologous marrow grafting ,
Indian J Orthop.2009 Jan-Mar; 43(1): 40-45
74. Bone Marrow Concentrate Stem Cells for Knee Arthritis
Centeno C, et al, Efficacy of autologous bone marrow concentrate
for knee osteoarthritis with and without adipose graft, Biomed Res
Int. 2014;2014:370621
75. Bone Marrow Concentration Stem Cell therapy compared to
Hyaluronic Injections Stem Cell group did better! Vega A, et
al,Treatment of KneeOsteoarthritis with Allogeneic Bone Marrow
Mesenchymal Stem Cells: A Randomized
ControlledTrial,Transplantation, 2015Aug;99(8); 1681-90
76. Bone Marrow Concentrate Stem Cells for Arthritis Larger
Groups Centeno, C et al, A dose response analysis of a specific
bone marrow concentrate treatment protocol for knee osteoarthritis,
BMC Musculoskelet Disord. 2015; 16:258
77. Long-Term Results Bone Marrow Concentrate StemCell Emadedin
M., et al, Long-Term Follow up of Intra-articular Injection of
Autologous Mesenchymal Stem Cells in Patients with Knee, Ankle or
Hip Osteoarthritis, Arch Iran Med. 2015, Jun;18(6): 336-44
78. Stem CellTherapy and Meniscus Repair HanaYu, et al,
Meniscus repair using mesenchymal stem cells- a comprehensive
review, Stem Cell ResTher. 2015; 6(1): 86.
79. LongerTerm Results of Stem CellTherapy for arthritis of
knee and hip 1128 54 months 91% had at least 50% improvement
Michalek J, Autologous adipose tissue-derived stromal vascular
fraction cells in patients with osteoarthritis, CellTransplant,
2015 Jan 20. doi: 10.3727
80. Arthroscopic Surgery
81. Safety Efficacy *Hagino, T et al Complications after
arthroscopic knee surgery. Achieves of Orthopedic Trauma Surgery ,
2014 November; 134(11):1561-4 **Herrlin, SV et al Is arthroscopic
surgery beneficial in treating non-traumatic, degenerative medial
meniscus tears? A five year follow-up . Journal of Knee Surgery,
Sports, Traumatology and Arthroscopy 2013 Feb;21(2):358-64
82. Arthroscopic Surgery
83. Arthroscopic Surgery
84. Joint Replacement Surgery What is it?
85. Joint Replacement Safety : 16% 3.4 % 10.9%
86. Reliable Reproducible Durable-
87. Patient Satisfaction after Joint Replacement 27%- 30% *Lam,
YF et al, A Review of the Clinical Approach to Persistent Pain
Following Total Hip Replacement, HongKongMedJ , 2016 Dec: 22(6):
600-7 **Wylde, V et al, Total Knee Replacement: Is it Really and
Effective Procedure for All?; Knee, 2007, Dec 14 (6): 417-23
88. Joint Replacement Costs Cost :
89. Joint Replacement
90. Convenience of Joint Replacement Require someone to help
24/7 for 3 weeks
91. Stem CellVs. Knee Replacement
92. Stem CellVs. Knee Replacement Stem Cell Group had Faster
improvement
93. Stem CellVs. Knee Replacement Knee Replacement Group had
Higher Longer Higher More Longer More medical complications
94. Stem CellVs. Knee Replacement higher patient satisfaction:
70% pointed to the stem cell knee
95. Success for Cell BasedTherapy Am I a candidate forCell
BasedTherapy? OR If your joint is stable with no or very rare
episodes of catching or giving away, you can consider cell based
therapies.
96. Success for Cell BasedTreatments Am I a candidate for cell
based therapy ? OR If your joint has only rare episodes of swelling
and you do not require draining more than 4 times per year, you can
consider cell based therapy
97. Am I a Candidate forCell Therapy ? OR If you have mild to
moderate bowing of your joint and you do not notice the bow under
your pants, you can consider cell based therapies
98. Success for Cell BasedTherapy Am I a candidate for Cell
Based Treatments? OR If you have mild to moderate loss of motion of
the joint and can dress yourself without any aids, you should
consider cell based therapies.
99. Have more than two surgical risk factors If you have more
than two of these risk factors, you should consider cell based
therapies
100. Success for Cell BasedTherapy Am I a Candidate for Cell
BasedTherapy? If you are not willing to undergo the risks,
commitments and inconveniences of joint replacement surgery you can
consider cell based therapy
101. Lower Risk Everyones welcome!
102. Must also figure in time lost from occupation may be
Payment plans available
103. Knee Arthroscopy Bone Marrow Stem CellAnd
104. Benefits of Stem CellTherapy with Surgery Proven Benefits
Less Expensive Less Painful- More Convenient-