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Necator americanus

Necator americanus

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Page 1: Necator americanus

Necator americanus

Page 2: Necator americanus

AMERICAN HOOKWORM

AMERICAN MURDERER

NEW WORLD HOOKWORM

Necator americanus

Synonym

Page 3: Necator americanus

NECATORIASIS

UNCINARIASIS

Necator americanus

Disease

Page 4: Necator americanus

Necator americanus

Historical NotesPredominant human hookworm in the

Philippines

Agent in the production of “laziness” in poor white population in the Southern USA;

“Tropical Anemia” of Puerto Rico and tropical areas in Western hemisphere

Page 5: Necator americanus

Necator americanus

MorphologyAdult Worm

• Attenuated anterior end w/ a buccal capsule

• Ventral and dorsal pair of semilunar cutting plates

• Strongly flexed dorsal ward the anterior end

Page 6: Necator americanus

Necator americanus

MorphologyAdult Worm

• Amphidial (secretes anticoagulant), excretory and esophageal glands for exodigestive function

• Grayish yellow at times reddish

Page 7: Necator americanus

Necator americanus

Morphology

Adult Male Worm

• 7-9mm long

• Long and wide bursa

Page 8: Necator americanus

Necator americanus

Morphology

Adult Male Worm

• Bipartite dorsal ray

• Long, slender and fused (forming delicate barb) copulatory spicules

Page 9: Necator americanus

Necator americanus

Morphology

Adult Female Worm

• 9-11mm long

• Vulva is situated either in middle or somewhat anterior

Page 10: Necator americanus

Necator americanus

Morphology

Eggs

• Resembles those of Ancylostoma duodenale

• Longer and more elongated than A.duodenale

• Daily egg output is 9,000 eggs

Page 11: Necator americanus

Necator americanus

Morphology

Diagnosis

• Subnormal level of hemoglobin with hookworm eggs in the feces (Hookworm disease)

• Egg number estimation (Egg count)

Page 12: Necator americanus

Necator americanus

Morphology

Diagnosis

• Presence of Charcot Leyden crystals in the feces (heavy infection : prepatent period)

• 24 hour fecal specimen preservation at room temp for egg hatching to hookworm larvae

Page 13: Necator americanus

Necator americanus

Morphology

Treatment

• Single dose of Benzimidazole antihelminthic

• Such as Albendazole or Mebendazole

Page 14: Necator americanus

Necator americanus

STORYANG BUTBOT

A. duodenale N. americanusStrong Weak

Larger and thicker Smaller and more slenderStunted Children Growth and Mental

Retardation

(I Have Enough Power)Iron-deficiency anemia,

Hypothermia, Eosinophilia, Protein Malnutrition

Classic Hookworm Disease

6 Ventral Cutting Teeth 4 Ventral Cutting Plate

No Lung Migration Requires Lung MigrationTripartite Dorsal Ray Bipartite Dorsal Ray

Present Spine Absent Spine

Anterior end bends in same direction Anterior end bends in opposite direction