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CONGENITAL ANOMALIES
Nur Amalina bt. Aminuddin Baki082012100067
Objectives
• To understand the congenital anomalies that can be present in o Thyroid glandso Parathyroid glandso Adrenal glands
Anomalies of Shape
• Pyrimidal lobe o Arise from isthmus or one of the lobesoMay have no connection with thyroid oMay be divided into two or more parts
• Isthmus may be absent• One of the lobes of gland
oMay be very small or absent
Anomalies of Position
• Lingual thyroido Under mucosa of dorsum of tongue oMay form swelling and difficulties in swallowing
• Intra- lingual thyroido Embedded in muscular substance of tongueo Suprahyoido Lie in midline of neck, above hyoid bone
• Infra- hyoid thyroid o Lie below hyoid bone, but above normal position
• Intra-thoracic thyroid o Entire gland or part of it may lie in the thorax
Ectopic Thyroid Tissue
• Found anywhere along path of descent of thyroid gland
• Commonly found in the base of tongue, just behind foramen caecum
Remnant of Thyroglossal Duct
• May persist and lead to formation of:• Thyroglossal Cyst
o Cystic remnant of thyroglossal ducto At any point along migratory pathway of thyroid
glando Always near or in midline off necko 50% - close or inferior to body of hyoid boneo Some at base of tongueo Some close to thyroid cartilage
• Thyroglossal FistulaoWhen thyroglossal cyst is connected to outside by
fistulous canalo Usually arises secondarily after rupture of a cystoMay be present at birth
• Carcinoma of thyroglossal duct
Adrenal Gland Anomalities• Ectopic adrenal cortical tissue• Ectopic adrenal gland– May lie deep to capsule of kidney– May be fused to liver or kidney
• Hyperplasia of Adrenal GlandoMale( adrenogenital syndrome)
Marked by early development of secondary sexual characters
oFemale( Pseudohermaphroditism)Enlargement of clitoris Child may be mistaken for male
Reference
• Human Embryology, 8th Edition, Inderbir Singh and G P Pal.
• Human Embryology, Langman’s