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Meaning affects our pain experience Lorimer Moseley NHMRC Senior Research Fellow Prince of Wales Medical Research Institute & School of Medical Sciences, University of New South Wales, Sydney, Australia Team leader The GAMFI project University of Oxford, UK Los Angeles, June 2009 © GL Moseley www.BodyInMind.com.au

Meaning affects our pain experience

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The context of a noxious stimulus affects the pain it evokes published in Pain 133, 1-3 64-71

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Page 1: Meaning affects our pain experience

Meaning affects our pain experience

Lorimer MoseleyNHMRC Senior Research FellowPrince of Wales Medical Research Institute & School of Medical Sciences, University of New South Wales, Sydney, Australia

Team leaderThe GAMFI projectUniversity of Oxford, UK

Los Angeles, June 2009

© GL Moseley www.BodyInMind.com.au

Page 2: Meaning affects our pain experience

The context of a noxious Stimulus affects the pain it evokesPain 133, 1-3 64-71

© GL Moseley www.BodyInMind.com.au

Page 4: Meaning affects our pain experience

Manipulated meaning of nociceptive stimulus

-20ºC probe

© GL Moseley www.BodyInMind.com.au

Page 5: Meaning affects our pain experience

Manipulated meaning of nociceptive stimulus - HOT

-20ºC probe “hot”

© GL Moseley www.BodyInMind.com.au

Page 6: Meaning affects our pain experience

Manipulated meaning of nociceptive stimulus - COLD

-20ºC probe “cold”

© GL Moseley www.BodyInMind.com.au

Page 7: Meaning affects our pain experience

Very cold (-20ºC) stimulus associated with a red or a blue light

0

5

10

Red light

Blue light

Pain

Moseley & Arntz 2007 PAIN In press© GL Moseley

www.BodyInMind.com.au

Page 9: Meaning affects our pain experience

Visual clues that imply more or less danger change the pain evoked by identical stimuli

© GL Moseley www.BodyInMind.com.au