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The liquid oral manufacturing plant is designed to be operated by one operator and one helper, saving on precious man-power costs. Sugar syrup and manufacturing vessels are provided with limpet coils for heating and cooling, designed for internal vacuum to facilitate transfer of sugar directly from stores to sugar syrup vessel.
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LIQUID ORALS
PRESENTED BY-
ANWAR MUNJEWAR
M.PHARM(QUALITY ASSURANCE TECHNIQUES)
ALLANA COLLEGE OF PHARMACY, PUNE-01
CONTENTS:
INTRODUCTION METHOD OF PREPARATION PROCESSING FLOW CHART FACILITY DESIGN DESIGN ASPECTS MAN POWER REQUIRMENT LAYOUT
INTRODUCTION
Preparation in Liquid forms either clear solutions, suspension or emulsions.
Sugar Syrup – Base or Vehicle in Medicament.
Ingredients Used – Colours, Flavours, Preservatives etc.
GENERAL METHOD OF PREPARATION
Preparation of Sugar Syrup with preservatives.
Addition of other ingredients and dissolving; medicinal substance and colour.
Cooled up to 35° C. Addition of Flavour. Volume make as per the design. Flittered and finished product is stored
PROCESSING FLOW CHART
Day StoreLiquid
Preparation
Bottle Washing
Bottle Filling and
SealingInspectionLabelling
Packaging In-process Storage
FACILITY DESIGN
FOR SMALL SCALE : 3000Lit/shift or 30,000 bottles/shift
1500kg sugar + other material per shift
1 Batch of 3000Lit/shift
Equipment Details Weighing Balance
Sifter
Mfg. Vessels for syrup
Storage vessels
Bottle washing, sealing and labelling machine
Conveyor belts
DESIGN ASPECTSSTANDARD LAYOUT FOR LIQUID ORALS
MAN POWER REQUIRMENTS
Sr. No.
Name of Work Station
Large Scale
Small Scale
1. Day Store 2 1
2. Liquid preparation room
4 1
3. Bottle Cleaning 4(2x2) 2
4. Bottle filling & sealing
4(2x2) 2
5. Bottle Inspection 4(2x2) 1
6. Bottle Recovery 2(1x2) 1
7. Bottle Labelling 2(1x2) 1
8. Online Packaging 20(10x2) 6
Total 44 15
No. Of Persons
LAYOUT TYPICAL LAYOUT FOR SINGLE LINE LIQUID ORALS
DEPARTMENT
THANK YOU !