Horizon 2020 brochure ttopstart - the horizon 2020 experts

Science and business consultants for life sciences, medical technology and health

Horizon 2020 experts

Horizon 2020 proposal writing Non-scientific management Dissemination & exploitation

Ontwerp: Studio Edwin de Boer

Horizon 2020 experts

4ttopstart - Horizon 2020 experts

Horizon 2020: the EU Framework Programme for Research and InnovationHorizon 2020 is the European grant and subsidy framework for innovation and R&D. The programme, running from 2014 to 2020, has a budget of €70 billion. Horizon 2020 is aimed at securing Europe’s global competitiveness. This will be done by:

• Raising the level of excellence of Europe’s science base to strengthen the EU’s position in science. World-class science is considered to stimulate and establish a basis for upcoming technologies, jobs and wellbeing. This requires the recruitment, development and retention of highly talented researchers. The Excellent Science pillar of Horizon 2020 is characterised by:

• Support of the most talented and creative researchers and their teams to carry out high-level frontier research.

• Funding of collaborative research of new and promising fields of research and innovation.

• Providing excellent training and career development opportunities for researchers.

• Providing researchers with access to world-class research infrastructure.

Horizon 2020 offers the perfect opportunity for academia and industry to finance research and development activities. Excellent Science, Competitive Industries and Tackling Societal Challenges are at the top of the strategic agenda.

What is Horizon 2020?

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• Investing in key technologies, better access to capital and support for Small and Medium Enterprises (SMEs) in order to make Europe a more attractive location to invest in research and innovation, thereby enforcing industrial leadership. Strategic investment in key technologies will support innovation in both existing and emerging sectors. The Competitive Industries pillar will focus on:

• Developing European industrial capabilities in so-called key enabling technologies, including nanotechnology and biotechnology.

• Facilitating access to risk finance by leveraging private finance and venture capital for research and innovation.

• Stimulating innovation in SMEs through fostering all forms of innovation in all types of SMEs.

• The Societal Challenges pillar will deal with helping to bridge the gap between research and the market in order to tackle societal challenges. This will be done by dealing with concerns shared by European citizens and will reflect policy priorities of the Europe 2020 strategy that cannot be achieved without innovation. Resources and knowledge across various fields will be brought together, activities from research to market will be covered and promising solutions will be tested and verified.

Horizon 2020: funding schemesThe funding schemes are largely consistent with the Seventh Framework Programme (FP7) and related previous programmes and consist of e.g. ERC Grants, ITN and IOF Grants, Collaborative and Integrating projects, Eurostars, IMI grants and debt and equity facilities for SMEs. However, a number of funding instruments are new within Horizon 2020, including the SME instrument and the fast track to innovation pilot.

Horizon 2020: new features• Horizon 2020 as a single programme

Horizon 2020 is a single programme combining FP7, the European Institute of Innovation and Technology (EIT) and the Competitiveness and Innovation Framework Programme (CIP). It is a one-stop shop for acquiring European project funding.

• Simplified set of financial rules The EU contribution is up to 100% of the total eligible costs for R&D projects and up to 70% for innovation projects. In all cases indirect costs will be covered by a flat rate of 25% of the direct costs.

• Increased participation of industry including SMEs Research and development within Public Private Partnerships is promoted, e.g.

through increased participation of industry, including SMEs.


At ttopstart, we combine science and business, specialising in the fields of life sciences, medical technology and healthcare.

ttopstart has been built on the unique combination of science and business, with a focus on the life sciences, medical technology and healthcare sectors. Our consultants have a solid scientific background combined with an extensive business skill set. This is a key advantage for your Horizon 2020 application, considering the increased EC demands for translation of research, public private partnerships and societal impact. Proposals do not leave our office without scientific and business excellence.

ttopstart is able to write 80% of the total application

ttopstart can write the Horizon 2020 proposal (in close contact with the consortium), allowing you to focus on the scientific work plan. ttopstart manages the entire application

process: from writing the body of the proposal, to collecting, streamlining and merging partner input, setting up detailed budget plans, distributing draft versions, handling partner feedback and final submission. This allows you to spend most of your time on the scientific quality and overall management.

ttopstart supports you with professional non-scientific management

Professional scientific and non-scientific management is a prerequisite foryour Horizon 2020 consortium - and highly appreciated by reviewers. In the application phase, we offer a big toolbox with proven management frameworks and can tailor a model for project management and consortium organisation that secures quality and quantity of the output. In the project phase, we are a strong consortium partner for non- scientific management; from monitoring and reporting deliverables, to organising meetings and drafting progress reports.

Why ttopstart

ttopstart is an innovative science and business consulting company with the ability to write 80% of your Horizon 2020 application. ttopstart has unique expertise in supporting you with non-scientific management, dissemination and exploitation activities during the project.

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ttopstart delivers high-quality dissemination and exploitation services for new and existing Horizon 2020 projects

Horizon 2020 was created to boost Europe’s competitiveness and increase scientific leadership. It should be very clear how your Horizon 2020 project will contribute to this goal. ttopstart specialises in developing creative and detailed stakeholder-sensitive plans for dissemination and exploitation of the proposed outcomes. Our experience in developing corporate business plans means that we can integrate a society-targeted vision in your proposal and set up a winning impact section. This becomes of real value once the project has been approved: ttopstart is the ideal dissemination & exploitation partner, ensuring that stakeholders are involved, output is IP protected and commercialised and the proposed impact is achieved.

ttopstart facilitates strategic preparations for a head start in Horizon 2020 Is your organisation or department fully prepared to take the lead (or take part) in Horizon 2020 projects? Are you confident that your projects will get funded? Building on years of experience in the field of European subsidies, ttopstart can rapidly analyse the competitiveness of your organisation in a subsidy context. Moreover, we can give practical recommendations for optimal preparation for success in Horizon 2020 - even prior to any application. Whilst not guaranteeing success, a head start will definitely increase your chances.

If you would like to have more detailed information on what ttopstart can do for you, do not hesitate to contact one of our consultants. For contact details, please go to page 18.


FP7 Project (AMC)Size: €6MTopic: Artificial liver device In the FP7 project BALANCE, the companies Hep-Art, Pharmacell and BioPredic joined forces with academic partners Amsterdam Medical Centre (AMC) and University of Edinburgh to offer Acute Liver Failure patients a bioartificial liver-support system for bridging the waiting period for liver transplantation or recovery of the diseased liver. The funding is being used to optimise the system and to execute clinical trials.

ttopstart supported AMC researchers of the Tytgat Institute to apply for a €6M FP7 subsidy for development of bioartificial organs. This resulted in the European project BALANCE.

Key achievements

IMI Project (University Utrecht/Sanofi-Aventis)Size: €30MTopic: Drug delivery An international consortium, coordinated by Utrecht University and Sanofi Aventis, was awarded a European grant for studying targeted delivery of biopharmaceuticals. The total project size is €30 million. The consortium consists of 16 academic institutes and several pharmaceutical companies. The project title is COMPACT - Collaboration to Optimise Macromolecular Pharmaceutical Access to Cellular Targets.

ttopstart supported University Utrecht and Sanofi-Aventis with acquiring an IMI Grant for research on biopharmaceutical delivery that resulted in the COMPACT project.

ttopstart has a sound track record in supporting academia and SMEs with the preparation of winning subsidy proposals. Over the past 3 years, more than 70% of our proposals were granted with multiple #1 rankings and high rankings in competitive European programs such as FP7, Eurostars and Innovative Medicines Initiative (IMI). Some examples:

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Other European grantsttopstart has many years of successful experience with acquiring numerous subsidies in life sciences and medical technology, such as FP7, IMI, EuroTransBio and Erasmus Mundus, but also with ERC grants and Eurostars.

• ERC grants: ttopstart has a good track record in attracting ERC grants. We have contributed to various approved ERC Starting Grants and ERC Advanced Grants. We also have ample expertise with ERC Proof of Concept Grants (12 out of 15 ERC PoC grants were funded). We not only support researchers with the application of the proposal, but we are also active in the granted project itself by providing our market intelligence and business development services.

• Eurostars: ttopstart has managed 7 successful Eurostars applications for different SMEs in throughout Europe. One of these applications was ranked as #1 out of 306 applications.

EuroTransBio Project (Microbiome)Size: €3.2MTopic: Chlamydia diagnostics

FP7 Project (Undisclosed)Size: €24MTopic: Clinical management in severe epidemics

Erasmus Mundus Project (VU University)Size: €6MTopic: Transdisciplinary global health

ERC Starting Grant (VU University Medical Center)Size: €1,5MTopic: Cancer diagnostics

FP7 Project (UMC St. Radboud)Size: 6MTopic: Breast cancer imaging

FP7 ICT - VPH Project (Fraunhofer MEVIS)Size: €6MTopic: Personalised predictive breast cancer


Our method

FitHigh-ranking projects show an ideal fit between the proposal and the call text. Both the consortium and the proposal must therefore seamlessly match with the EC's intentions. To optimise this fit, ttopstart assists in: • Finding strong consortium partners -

academic and industrial• Critically assessing and strengthening

your initial project plan

“Through our experience and a devil's advocate attitude we are able to rapidly assess whether a proposal idea has winning potential.”

“Our approach is acknowledged for its efficiency and harmony in the consortium.”

FrameworkUniting the visions of 5 - 30 partners into a synchronised and solid proposal is one of the main challenges for constructing a winning bid. ttopstart offers the tools to design a conceptual framework in which the consortium's plans can be integrated and fine-tuned towards a logical work plan. We use problem analysis methods and the ‘Pyramid Principle’ in Horizon 2020 style in which we:• Analyse the major problem – focal

problem – sub challenges• Define the ultimate goal – project

objective – sub objectives• Connect work packages and impact to

these items

ttopstart has developed the FFWD model to fast-forward you from an innovative vision to a winning Horizon 2020 proposal. We are highly motivated to succeed due to our risk-bearing strategy. We specialise in impact, for the consortium and for society.

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WriteDeveloping a convincing proposal requires excellent writing skills, a quality that is certainly demonstrable in the ttopstart team. ttopstart ensures a persuasive presentation of the proposal by applying the seven C's of effective communication: clear, concise, concrete, correct, coherent, complete and courteous. ttopstart guards timeliness and coordinates the entire application process - which can be as demanding as the writing part.

DevelopmentCommercialisation, impact, dissemination and exploitation are now a central part of all Horizon 2020 proposals. ttopstart excels at these sections because of our extensive business consulting experience. ttopstart offers detailed market intelligence and business development strategies to leverage societal and economic impact. During the application phase and the course of the project, ttopstart is your management and impact partner. We offer a variety of (tailored) packages to facilitate productive management, exploitation and dissemination."Our writing skills guarantee an application

that is both accessible and interesting."

“Combining scientific and business expertise in your project results in high impact publications and valuable innovations."

Submission Review EC Negotiation

Knowledge utilisationProject management

Development

Consortium formation

FitConceptualisation of research plan

FrameworkProposal preparation

Write


Societalchallenges

Industrial leadership

Excellentscience

∙ European Research Council∙ Marie Sklodowska-Curie Actions

∙ Future and Emerging technologies

∙ Research infrastructures

∙ Health, demographic change and wellbeing

∙ Inclusive, innovative and secure societies

∙ Leadership in enabling and industrial technologies∙ Access to risk finance∙ Innovation in SMEs

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Excellent Science European Research Council (ERC)The ERC is the foremost funding agency for excellent science in the EU under Horizon 2020. The ERC mandate is to encourage the highest quality research in Europe through competitive funding and to support investigator-initiated frontier research across all fields of research, on the basis of scientific excellence.

The main funding schemes of ERC are: • The ERC Starting Grant that aims to support top researchers with 2 to 7 years

of experience after their PhD. • The ERC Consolidator Grant that is designed to support top researchers with

7 to 12 years of scientific experience after their PhD. • The ERC Advanced Grant that is open to excellent established researchers who

are leaders in their field of research. • The ERC Proof of Concept Grant is meant for ERC grant holders to bridge the

gap between research and the earliest stage of marketable innovation.

The Marie Sklodowska Curie ActionsThis Work Programme is open for all domains of research and innovation, from basic research up to market take-up and innovation services. Research and innovation fields as well as sectors can be freely chosen by the applicants. This Work Programme helps researchers to have a more stable career path and ensures that they can achieve an appropriate work/life balance. An important aspect of the Marie Sklodowska Curie Actions is mobility. Researchers receive funding on the condition that they move from one country to another to broaden or deepen their competences.

H2020 Work Programmes

ttopstart is able to provide support with the writing and coordination of all proposals relevant for academia and industry in life sciences, medical technology and healthcare. This concerns topics from the following Work Programmes: ERC; the Marie Sklodowska Curie Actions; Leadership in Enabling and Industrial Technologies; Health, Demographic Change and Wellbeing; and Eurostars.


The Marie Sklodowska Curie Work Programme includes the following calls: • Innovative Training Networks (ITN). This action aims to train a new generation

of creative, entrepreneurial and innovative researchers to be able to face current and future challenges and to convert knowledge and ideas into products and services for economic and social benefit.

• Individual Fellowships (IF). The goal of this action is to enhance the creative and innovative potential of experienced researchers who wish to diversify their individual competence in terms of skill acquisition at multi- or interdisciplinary level through advanced training, international and intersectoral mobility.

• Co-funding of regional, national and international programmes (COFUND). This action aims to stimulate regional, national or international programmes in order to foster excellence in researchers' training, mobility and career development, spreading the best practices of Marie Sklodowska-Curie Actions.

• Research and Innovation Staff Exchange (RISE). This action aims to increase public awareness of research and innovation activities in Europe, with a view to supporting the public recognition of researchers, creating an understanding of the impact of researchers' work on daily life and encouraging young people to embark on scientific careers.

Industrial LeadershipLeadership in enabling and industrial technologies (LEIT)The focus of this Work Programme is on new opportunities for industrial leadership in ICT, the mastering and deployment of key enabling technologies and space. LEIT aims to develop breakthrough technologies that boost competitiveness, creating jobs and supporting growth. Within LEIT, two Work Programmes are relevant for Health and Life Sciences: ‘Information and communication technologies’ and ‘Nanotechnologies, Advanced Materials, Biotechnology and Advanced Manufacturing and Processing’.

Information and Communication Technologies (ICT)ICT enables scientific progress in all disciplines and underpins innovation and competitiveness across a broad range of private and public markets and sectors. The potential and capabilities of modern ICT systems are still growing exponentially, fuelled by the progress in electronics, microsystems, networking, the ability to master increasingly complex cyber-physical systems and robots, and the progress in data processing and human machine interfaces. This Work Programme contains topics on information management, robotics and micro-and nano-electronic technologies that are of interest for stakeholders in life sciences, medical technology and healthcare.

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Nanotechnologies, Advanced Materials, Biotechnology and Advanced Manufacturing and ProcessingNanotechnology and advanced materials are key drivers for breakthrough innovations in many fields. This Work Programme identifies a number of activities to foster their potential to enable e.g. new medical therapies contributing to personalised healthcare. This call will contribute to a technological basis for nanomedicines and bio-materials by bringing it towards pilot production as precondition for subsequent clinical trials. The biotechnology projects aim to develop generic technological building blocks, enabling true stepping stones towards solutions for, amongst others, better health.

The Industrial Leadership Work Programme includes the following types of projects: • Research and innovation projects: research projects with potential innovative

elements where the participation of third country entities is required or preferentially evaluated.

• Innovation projects (demo, pilot, market replication).• SME instrument: this instrument aims to fill gaps in funding for early-stage,

high-risk research and innovation, as well as for breakthrough innovations by SMEs. The new instrument will integrate research and innovation (R&I-) related SME support that is currently spread across several programmes and initiatives into one comprehensive, simple and easily accessible scheme. It will target highly innovative SMEs showing a strong ambition to develop, grow and internationalise, regardless of whether they are high-tech and research-driven or non-research conducting, social or service companies.

• Coordination and support Action: project where supporting activities are central.

• ERA-NET: a collaborative project between member states.

Societal Challenge Health, Demographic Change and WellbeingThis Work Programme includes topics on personalising health and care that aim to create opportunities for real breakthrough research and radical innovation in response to challenges such as the ageing population and the increasing communicable and non-communicable disease burden. Improving health outcomes, reducing health inequalities and promoting active and healthy ageing is key in this call. Activities that fit in this call will improve our understanding of the causes and mechanisms underlying health, healthy ageing and disease; improve the ability to monitor health and prevent, detect, treat and manage disease; support elderly people in remaining active and healthy; and test and demonstrate new models and tools for health and care delivery.


This Work Programme consists of the following types of projects: • Collaborative projects: Research and development in Public Private Partnerships

is promoted, e.g. through increased participation of industry, including SMEs, in collaborative projects such as research and innovation actions, innovation actions and coordination and support actions.

• SME instrument: this instrument aims to fill gaps in funding for early-stage, high-risk research and innovation as well as for breakthrough innovations by SMEs. The new instrument will integrate research and innovation (R&I-) related SME support that is currently spread across several programmes and initiatives into one comprehensive, simple and easily accessible scheme. It will target highly innovative SMEs showing a strong ambition to develop, grow and internationalise, regardless of whether they are high-tech and research-driven or non-research conducting, social or service companies;

• Coordination and support Action: project where supporting activities are central;• ERA-NET: a collaborative project between member states.

OtherEurostars Research-intensive SMEs are addressed by Eurostars 2, the follow-up of the successful Eurostars programme. Eurostars aims to support R&D performing SMEs by co-financing market-oriented innovation with a bottom-up approach. With streamlined and improved procedures, Eurostars 2 will promote technological and business development, whilst boosting employment and export for European small businesses.

If you would like to receive more detailed information on specific Horizon 2020 topics, please contact one of our consultants.

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ERC StG V VERC Con. V VERC AdG V VERC PoC. V VITN V V V VIF V V V VCOFUND V V V VRISE V V V VR&I projects V VInnovation projects VSME instrument V V VSCA V VERA-NET V VPRIZE V VPCP V VPPI VCP V V VEurostars V V V

Educatio

n

Overview of the Horizon 2020 funding instruments set against various forms of research.

Fundamental

research

Translatio

nal

research

Applied

research

Development


Contact us

For more information please contact one of our consultants or visit our website at www.ttopstart.com

Jochem Bossenbroek MSc. - partner [email protected]+316 2244 2641

Marieke van Kouwenhove PhD - [email protected]+316 4209 2199

Patrick de Boer MSc. - partner [email protected]+316 5389 7487

ir Jasper Levink - [email protected]+316 3434 2333

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About ttopstart

ttopstart is a science and business consulting company that serves leading researchers and innovative companies in the fields of life sciences and medical technology. We acquire funding for cutting-edge research and development, co-create corporate strategies and conduct detailed market assessments. Our driver is the contribution to development of innovations that can strongly advance healthcare, such as diagnostics and treatments for a wide range of diseases with unmet medical needs.

www.ttopstart.com

Health & Medicine

Horizon 2020 brochure ttopstart - the horizon 2020 experts