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30/05/2013
1
© Vlerick Business School Prof Dr Walter Van Dyck
THE HEALTHCARE ECOSYSTEM OF THE FUTURE
PROF DR WALTER VAN DYCK
30/05/2013
2
© Vlerick Business School Prof Dr Walter Van Dyck
IN THE NEXT DECADE IT WILL COST $100 AND TAKE LESS THAN ONE HOUR TO SEQUENCE A HUMAN
GENOME
© Vlerick Business School
AND IT GOES EVEN FASTER THAN PREVIOUS DISRUPTIVE TECHNOLOGY CYCLES
Prof Dr Walter Van Dyck
30/05/2013
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© Vlerick Business School
So what does personalized medicine mean for the health care ecosystem of the future?
Prof Dr Walter Van Dyck
© Vlerick Business School
GENERAL IMPACT OF PERSONALIZED MEDICINE ON THE HEALTH CARE ECOSYSTEM
Prof Dr Walter Van Dyck
Integrated solution-based therapies
Health outcome-based therapies possibly allowing for patient self-management
Analytics (Big Data)-driven therapy development
Open innovation and collaboration across health sectors
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© Vlerick Business School
FADING INDUSTRY BOUNDARIES OFFERING LOTS OF OPEN INNOVATION OPPORTUNITIES
Prof Dr Walter Van Dyck
Stremersch & Van Dyck (2009)
1. TWO STUDIES ON THE IMPACT OF PERSONALIZED MEDICINE ON THE HEALTH CARE ECOSYSTEM
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© Vlerick Business School
DOES TECHNOLOGY-ENABLED PERSONALIZATION ALLOW FOR A MOVE FROM PURE PLAY DRUG-BASED TO INTEGRATED HEALTHCARE SOLUTIONS?
Prof Dr Walter Van Dyck
© Vlerick Business School
FROM CURE TO CARE
PREDICTION PREVENTION TREATMENT MONITORING
Prof Dr Walter Van Dyck
30/05/2013
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© Vlerick Business School
FROM CURE TO CARE
PREDICTION PREVENTION TREATMENT MONITORING
Acute Coronary Syndrome
Breast cancer
Prof Dr Walter Van Dyck
© Vlerick Business School Prof Dr Walter Van Dyck
30/05/2013
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STUDY 1: BREAST CANCER
© Vlerick Business School
DESCRIPTION OF SCREENING PROGRAMS FOR BREAST CANCER IN THE MODEL
Van Dyck et al (2012)
Prof Dr Walter Van Dyck
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© Vlerick Business School
STUDYING PATIENT POPULATION BEHAVIOUR USING A MARKOV STATE DIAGRAM
Undiagnosed or
disease free
Pre-Cancer
Local Cancer
Locally Advanced Cancer
Metastatic Cancer
Death due to Cancer
Death due to other
causes
(State Diagram adapted from NICE Guidelines) Van Dyck et al (2012)
Prof Dr Walter Van Dyck
© Vlerick Business School
0
500
1000
1500
2000
2500
3000
Current Situation "EHR+SNP" Scenario
ON AVERAGE, THE IMPLEMENTATION OF NEW SCREENING STRATEGY REDUCES TOTAL PATIENT COST OF HEALTHCARE BY 37% WITHOUT AFFECTING AVERAGE QALY
€
Average Cost per Patient over 25 years Average QALY per Patient
-37%
0
5
10
15
20
25
Current Situation "EHR+SNP" Scenario
0.1%
QALY
* Willingness-to-pay = 35.000 € / QALY
Van Dyck et al (2012)
Prof Dr Walter Van Dyck
30/05/2013
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© Vlerick Business School
A MOVE TO THE ENTRY POINT OF THE CLINICAL PATHWAY
Van Dyck et al (2012)
Prof Dr Walter Van Dyck
© Vlerick Business School
AS A RESULT OF THE NEW STRATEGY, SCREENING ACTIVITIES RISE WHILE CONSUMPTION OF EXPENSIVE TREATMENTS AND DIAGNOSTIC TESTS FOR ADVANCED STAGES OF THE DISEASE DECLINE.
0
0,005
0,01
0,015
0,02
CurrentSituation
"EHR+SNP"Scenario
Herceptin
-28%
0
0,005
0,01
0,015
0,02
CurrentSituation
"EHR+SNP"Scenario
Immunohistochemistry
-48%
Y-Axis: average consumption per patient over 25 years * Radiotherapy and Hormone Therapy change in a similar proportion and have similar consumption volumes
Tre
atm
ents
D
iagnostic T
ests
0
0,005
0,01
0,015
0,02
Current
Situation
"EHR+SNP"
Scenario
Chemotherapy
-19%
Van Dyck et al (2012) Prof Dr Walter Van Dyck
0
1
2
3
4
5
6
7
8
CurrentSituation
"EHR+SNP"Scenario
Mammography (in Screening)
+18%
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STUDY 2: CARDIOVASCULAR DISEASES
© Vlerick Business School
INTEGRATING THE USE OF LIFE SCIENCES TECHNOLOGIES TO COMBAT CARDIO DISEASES
Prof Dr Walter Van Dyck
30/05/2013
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© Vlerick Business School
RESULTING IN DRAMATICALLY IMPROVED HEALTH OUTCOMES
Prof Dr Walter Van Dyck
© Vlerick Business School
THE HEALTH CARE ECOSYSTEM OF THE FUTURE
Moving to prevention and predicting health outcomes
Moving to health outcome monitoring & management
Moving to increased collaboration across life sciences technologies and competences
Prof Dr Walter Van Dyck
30/05/2013
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2. LIFE SCIENCES BUSINESS MODELS IN AN ERA OF PERSONALIZED MEDICINE
© Vlerick Business School
The personalized medicine-enabled health care ecosystem
welcomes a high variety of business model types
Prof Dr Walter Van Dyck
30/05/2013
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© Vlerick Business School Prof Dr Walter Van Dyck 25
Van Dyck & Debruyne (2012)
© Vlerick Business School
TECHNOLOGY-BASED BUSINESS MODEL ARCHETYPES
Prof Dr Walter Van Dyck 26
Van Dyck & Debruyne (2012)
30/05/2013
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© Vlerick Business School
TECHNOLOGY PLATFORM DEVELOPER: GENERATING AND MONETIZING IP FROM GENOTYPE MEETING PHENOTYPE
Prof Dr Walter Van Dyck
© Vlerick Business School
SOLUTION DEVELOPER: INCREASED BIOPHARMA-HIGH TECH COLLABORATION IN LIFE SCIENCES
Prof Dr Walter Van Dyck
30/05/2013
15
© Vlerick Business School
TECHNOLOGY PLATFORM DEVELOPER AND SOLUTION DEVELOPER: CREATING RESPECTIVELY A CO-INVENTION OR CO-DEVELOPMENT ECOSYSTEM
Prof Dr Walter Van Dyck
© Vlerick Business School
IMEC IAP: A TYPICAL TECHNOLOGY PLATFORM DEVELOPER BUSINESS MODEL
Prof Dr Walter Van Dyck
30/05/2013
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© Vlerick Business School
BIOPHARMA HEALTH CARE SOLUTION PROVIDERS MOVING ‘BEYOND THE PILL’
Prof Dr Walter Van Dyck
© Vlerick Business School
LIFE SCIENCES BUSINESS MODELS IN THE HEALTH CARE ECOSYSTEM OF THE FUTURE: OUTCOME-DRIVEN, ENABLING PATIENT SELF MANAGEMENT, OPEN INNOVATION & COMMUNITY-DRIVEN, FEDERATED, PLATFORM-BASED, AND BIG DATA-LEARNING-ORIENTED
Prof Dr Walter Van Dyck
*: Company names shown for illustrative purpose only. They do not necessarily correspond to reality
30/05/2013
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© Vlerick Business School
CUSTOMISED MANAGEMENT PROGRAMMES UNLEASH THE TRUE POTENTIAL OF YOUR PEOPLE & YOUR ORGANISATION
Customised Management Programmes are impactful learning solutions meeting your specific business needs. The health & life sciences industry is one of Vlerick Business School’s 4 strategic focus industries.
2012 facts and figures:
121 customised programmes for 84 different companies
4.529 participants in 14 countries worldwide
above 80 % satisfaction rates
Some of our health & life sciences customers:
Want to know more? Feel free to contact Anne Salenbien
+32 9 210 98 72| +32 472 28 56 06 | [email protected]
© Vlerick Business School
OPEN ENROLMENT PROGRAMMES EXECUTIVE EDUCATION PROGRAMMES FOR EXPERIENCED PROFESSIONALS
Our programmes address today’s most relevant business issues. You can choose between short, but intensive courses and long-term programme formats. 2012 facts and figures:
85 management programmes
3.859 participants
100% of our participants would recommend the ‘Management for the Hospital Professional’ programme to their colleagues!
Some of our health & life sciences customers:
Dr. Frank Verbeeck Foundation for PsychoGeriatry
Scheutbos Hospital
"I have to thank Vlerick for the organisation and quality of the Management for the Hospital
Professional programme. I have taken courses with IMD and INSEAD in the past, but what Vlerick offers is of an equivalent and even superior level.“
Dr. Manu Verholen
Sint-Vincentiusziekenhuis Deinze Anesthesist-Intensivist-Algologist
"This high quality management
programme sparks my entrepreneurial ambition to critically reflect upon the
(current) hospital policy in all its aspects. Creativity and reasoning
behavior are stimulated by a continuous interaction between faculty and hospital
professional."
Want to know more? Visit us online or contact us:
www.vlerick.com/ziekenhuis | +32 9 210 92 46 | [email protected]