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GIANT CELL LESIONSGIANT CELL LESIONS
GIANT CELL PREPHERAL GIANT CELL PREPHERAL GRANULOMA.GRANULOMA.
GIANT CELL GRANULOMA.GIANT CELL GRANULOMA. GIANT CELL TUMOUR.GIANT CELL TUMOUR. BROWN TUMOUR OF BROWN TUMOUR OF
HYPERPRATHYRODISM.HYPERPRATHYRODISM. FIBROUS DYSPLASIA.FIBROUS DYSPLASIA. CHERUBISM.CHERUBISM. ANEURYSMAL BONE CYST.ANEURYSMAL BONE CYST.
GIANT CELL PREPHERALGIANT CELL PREPHERAL
GRANULOMA GRANULOMA
CLINICAL PICTURECLINICAL PICTURE
22ndnd -3 -3rdrd decades decades Slight fem.Slight fem. Gingiva –Alv.P.Gingiva –Alv.P. Mand. > maxMand. > max Ant. 1Ant. 1stst. Molar. Molar Small well Small well
circumscribed easy circumscribed easy to bleedto bleed
Teeth displacement.Teeth displacement.
RADIOGRAPHYRADIOGRAPHY
ONLY WHEN BONE RESORBED.ONLY WHEN BONE RESORBED.
SAUCERIFORM DEPRESSION SAUCERIFORM DEPRESSION
OROR
PREPHERAL CUFFING.PREPHERAL CUFFING.
DIFF. DIAG.DIFF. DIAG.
PYOGENIC GRANULOMA.PYOGENIC GRANULOMA.
CENTERAL GIANT CELL GRRNULOMA.CENTERAL GIANT CELL GRRNULOMA.
FIBROEPITHELIA POLYP.FIBROEPITHELIA POLYP.
PREPHERAL CEMENTIFYING FIBROMAPREPHERAL CEMENTIFYING FIBROMA
FIBROMA.FIBROMA.
PYOGENIC GRANULOMAPYOGENIC GRANULOMA
FIBRO EPITHELIL POLYP.FIBRO EPITHELIL POLYP.
PYOGENIC GRANULOMAPYOGENIC GRANULOMA
CENTERAL GINT CELLCENTERAL GINT CELL
GRNULOMA GRNULOMA
CLINICAL PICTURECLINICAL PICTURE
CLINICAL PICTURECLINICAL PICTURE 10-20 YEARS.10-20 YEARS.
SILGHT FEM.SILGHT FEM.
MAND. > MAXMAND. > MAX ANT. MAND.SLOW GROWING.BONY HARD & MAY ANT. MAND.SLOW GROWING.BONY HARD & MAY
PAINFULPAINFUL
CORTICAL EXPANSION,LOOSENING &EXFOL. OF CORTICAL EXPANSION,LOOSENING &EXFOL. OF TEETH.TEETH.
MAY PERFOR.CORTEX.MAY PERFOR.CORTEX.
RADILOGYRADILOGY
MULTI. OR UNILOCULAR MULTI. OR UNILOCULAR
RADIOLUCENCYRADIOLUCENCY
DIFF. DIAG.DIFF. DIAG.
HYPERPRATHYROIDISM.HYPERPRATHYROIDISM. GIANT CELL TUMOUR.GIANT CELL TUMOUR. AMELOBLASTOMA.AMELOBLASTOMA. ODNT. KERATOCYST.ODNT. KERATOCYST. AN.BONE CYST.AN.BONE CYST.
TTTTTT
SURG. EXC.& THROUGH CURETTAGESURG. EXC.& THROUGH CURETTAGE
GIANT CELL TUMOURGIANT CELL TUMOUR
RARE IN THE JAWS.RARE IN THE JAWS.
AGGRESSIVE , METASTISISE.,INC. AGGRESSIVE , METASTISISE.,INC. REC.REC.
BETTER IN JAWS.BETTER IN JAWS.
IDENT. HIST.IDENT. HIST.
BROWN TUMOUR OF BROWN TUMOUR OF HYP.PARATHHYP.PARATH
Primary hyperprath. : +PTH –Primary hyperprath. : +PTH –Adenoma , hyperpl. Adenoma , hyperpl. Ca .Ca .
22ndnd . Hyperparath. ; hyp. –renal fail., . Hyperparath. ; hyp. –renal fail.,
osteomalacia.m.myeloma.osteomalacia.m.myeloma.
PresentationPresentation Fatigue ,weakness,anorexia, polyuria thirst Fatigue ,weakness,anorexia, polyuria thirst depression.depression.
Bone pain path.f#& coma.Bone pain path.f#& coma.
Clinic. Raod. Hist. --- GCG.Clinic. Raod. Hist. --- GCG.
LOSS OF LAMINA DURA. ERROSIVE LESIONS IN LOSS OF LAMINA DURA. ERROSIVE LESIONS IN THE PH. HAND & KNEE.THE PH. HAND & KNEE.
RENAL CALICUL.IRENAL CALICUL.I
LAB. INVEST.LAB. INVEST.
+ SERUM CA.+ SERUM CA.
+ PTH LEVEL.+ PTH LEVEL.
T T TT T T
UNDERL. CAUSE.UNDERL. CAUSE.
CALCITONINE.CALCITONINE.
Fibrous dysplasiaFibrous dysplasia
B –f-os m.B –f-os m.
Mom.f.d.Mom.f.d.
Poly.f.d.Poly.f.d.
Albright Syn.& Jaffe synd.Albright Syn.& Jaffe synd.
Rad.Rad.
Ground glass.Ground glass.
Diff. diag.Diff. diag.
Paget disease of bone.Paget disease of bone.
Oss-cement. Fibroma.Oss-cement. Fibroma.
Garre s osteom.Garre s osteom.
Garres osteom.Garres osteom.
Garres osteom.Garres osteom.
G. Ost.G. Ost.
T T TT T T
Cortical shaving.Cortical shaving.
Remission.Remission.
CherubismCherubism
Hereditary ,bilat. Sym. Enl.Hereditary ,bilat. Sym. Enl. Mand.Mand. 5 years.5 years. M.>f. M.>f. Heavenward look.Heavenward look.
Cheurbism.Cheurbism.
Rad.Rad.
Cheurbism.Cheurbism.
CherubismCherubism
PresentationPresentation
11stst -2 -2nd nd
Female.Female.
max. > mand.max. > mand.
Painless , slow grow.unilat.Painless , slow grow.unilat.
Cortical expansion. Displacement of Teeth.Cortical expansion. Displacement of Teeth.
Pathological FracturePathological Fracture
T T TT T T
Self-limited ,Reg. after puberty Self-limited ,Reg. after puberty
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