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THE CHALLENGE OF ACHIEVING WORLD CLASS CANCER CARE AND GROWING LONG DISTANCE CANCER ADVISORY AND GENOMIC TESTING IN EMERGING MARKETS
GLOBAL CARE, EVERYWHERE”
EXECUTIVE SUMMARY
This presentation explores these needs and details the potential opportunity to be developed and a way to serve this need by developing service networks linking US Genomic Labs and Cancer Centers with international patients in Emerging Markets; TestAnalytika as a Value Added Integrator enables this relationship
Confidential and for discussion only 2
Talks:3 dozen top oncologists
Survey:50+ oncologists
Problems affecting patients:1) Ordering and Follow up2) Certified translations3) Payments & Logistics4) US advisory and know
how5) Insurance Co. buy inSolutions- access to: - Advanced genomic tests & results - Referential Treatment Protocols &
Diagnostic Decision Support- Cancer Management techniques and US
Cancer Center Long Distance Advisory- Insurance Coverage & Prepay payment
aids
Not available in Emerging Markets- Support in locating, ordering and
interpreting US based molecular diagnostic Genomic Tests
- Easy access to US based Cancer Center Support
05/01/2023Confidential and for discussion only 3
THE CHALLENGE OF MAKING A HIGHER LEVEL OF CANCER CARE ACCESSIBLE FOR EXPATS
Top level cancer diagnosis &
Genomic Testing
The Gap
• Affordability / Lack of insurance Coverage
• Lack of access and follow up• Language barriers• Logistics issues• Interpretation of results
Expat Families
05/01/2023Confidential and for discussion only 4
THE CHALLENGE OF MAKING A HIGHER LEVEL OF CANCER CARE ACCESSIBLE FOR EXPATS
Expat Families
• Insurance Coverage• IT Platform for tracking and
follow up + EMR transmission
• Translation of results• Coordination with Fedex• Links with US Cancer Centers
for Remote Advisory and Diagnostic Decision Support
Our Proposal
Top level cancer diagnosis &
Genomic Testing
Confidential and for discussion only
THE CHALLENGE OF MAKING A HIGHER LEVEL OF CANCER CARE ACCESSIBLE FOR EXPATS
The Gap is Closed
IMPROVING ACCESS TO MEDICINES AND ONGOING
THERAPEUTIC SUPPORT WOULD COME IN PHASE II
05/01/2023Confidential and for discussion only 6
The Challenge
The Target Market
Our Proposal
Go to Market
Business Plan
Team
05/01/2023Confidential and for discussion only 7
The ChallengeWhat the Problem is in Emerging Markets for Expats and Others
05/01/2023 8
CANCER INCIDENCE IN LATIN AMERICA AND CARIBBEAN (LATAM-C) IS AROUND ONE MILLION CASES PER YEAR, CONCENTRATED IN FIVE MAJOR CANCER TYPES AND WITH STRONG LONGTERM GROWTH
The Challenge
05/01/2023Confidential and for discussion only 9
CANCER INCIDENCE IN LATIN AMERICA AND CARIBBEAN (LATAM-C) IS AROUND 70% OF THE USA’S, YET FIVE YEAR CANCER SURVIVAL RATES IN LATAM-C ARE ONLY 50% OF THE USA’S
While Latin Americans contract cancer at lower rates than residents of the United States, they are nearly twice as likely to die from it, the (Lancet) study said … "If corrective action is not taken this problem will become magnitudes of order bigger than it is today, it will create massive human suffering and it will threaten the economies of the region," Paul Goss, a professor at Harvard Medical School who led the study, said at an event in Sao Paulo on Friday. 04/26/2013http://www.huffingtonpost.com/2013/04/26/latin-america-cancer-epidemic_n_3165463.html
http://globocan.iarc.fr/ 2012
US vs LatAm-C Incidence and Mortality
50%
70%
The Challenge
Equal
05/01/2023Confidential and for discussion only 10
TWO SOLUTIONS HAVE STOOD OUT FOR US TO ADDRESS:1) ACCESSING US BASED CANCER CARE AND 2) ACCESSING US BASED CANCER LABORATORIES
US BASED CANCER CARE
Alliances between US medical institutions via partnership or sister institution agreements with leading LatAm Hospitals and Medical Centers
US BASED LABORATORIES US Labs have
established alliances with LatAm medical and pharmaceutical reps to represent them and develop business in LatAm
The Challenge
IMPROVING ACCESS TO MEDICINES
AND ONGOING
THERAPEUTIC SUPPORT
WOULD COME IN PHASE II
Confidential and for discussion only 11
US HOSPITALS HAVE LONG BEEN ATTRACTIVE FOR THE INTERNATIONAL MARKET SEEKING TOP LEVEL CARE – BUT LIMITED TO HIGH INCOME INDIVIDUALS
http://www.forbes.com/2008/05/25/health-hospitals-care-forbeslife-cx_avd_outsourcing08_0529healthoutsourcing.html
The Challenge
McKinsey & Co.:Medical Travelers to USA60K to 80K per year
Medical Travelers:32% want better care15% quicker access9% lower prices4% low cost procedures
Latin America has been mentioned as representing a proportionally higher number of patients for US medical centers
In Depth: U.S. Hospitals Worth The Trip, but affordable only by the top 1-3%
05/01/2023 12
GENOMIC CANCER TUMOR PROFILING AND OTHER US BASED GENOMIC LAB SUPPORT HAVE NOT GAINED MUCH TRACTION IN LATIN AMERICA VS. INHERENT POTENTIAL
FIRST WORLD GROWTH
The Challenge
LATIN AMERICAN CHALLENGES “ We frequently encounter delays of up to
three our four months in receiving our biopsy results because we have no direct contact with the laboratory doing the genetic testing.”
- Argentine physician “ We do not send many samples to the US
because for us the process is difficult and complicated. Many of my colleagues do not speak English.”
- Peruvian physician “the process is slow, expensive and
complicated… it would be interesting to have an easier method.. .Through our agreement with Johns Hopkins, we have access to their treatment protocols and opinions, but it is a very slow and complicated process.”
- Chilean physician
BOTH SOLUTIONS HAVE UNDERPERFORMED vs THEIR POTENTIAL (1)
Conflict between feeder model of bringing patients to the US and extension model of leveraging intellectual capital overseas
Lack of a clear business strategy, low priority and subordination to US based growth or international exposure in more important regions
Lack of clarity and alignment in relationship with foreign medical institutions Informal definition of support relationship – frequently only dependent upon periodic
teleconference case discussions No clear business model as to how to generate revenues and create mutual value from the
relationship – ‘sister institution’ not linked to goals - ‘Ad hoc’ model of support only when called upon
Low level of accountability for growth or development of the relationship and no P&L responsibility
Not tied in to other global initiatives done by institutions such as development of Fellows, Post Doctorate internships and use of international Alumni as a point of contact and growth
US institution may invest in the relationship and not develop channels to harvest many potential benefits
Separation between the Academic and the Clinical sides are failing to exploit synergies and economies of scale, relationships and branding among the different areas – ‘feudal castles’
05/01/2023Confidential and for discussion only
EXPANSION OF US BASED CANCER CARE
The Challenge
05/01/2023Confidential and for discussion only
BOTH SOLUTIONS HAVE UNDERPERFORMED vs THEIR POTENTIAL (2)
1. Logistics issues and enrollment problems due to a limited non-US focus of these labs and lack of flexibility for non-US patients in term of sign up (web pages focused on US market only, US dollar payment only, English language results only).
2. Follow up on test progress and lack of “Concierge Service” - difficulty in following up progress of clinical analyses through the laboratory and Annotation processes.
3. Difficulty in interpreting lab results due to language difficulties and limited MD experience base in evaluating impact of genomic tests on therapies, lack of Diagnostic Decision Support integrating Clinical History with test results and Annotations
4. High out of pocket costs – USD 7,000 – 10,000 per case w/o insurance coverage in practically all cases and problems with access to US Dollars in certain countries
5. Translation of results into local language; certification of EMR translations into English
6. Overall, a fragmented value chain and no one to integrate multiple players
US BASED GENOMIC LABORATORIES
The Challenge
LINKING US GENOMIC TESTING PLUS LONG DISTANCE CANCER ADVISORY SERVICES COULD BE A POWERFUL ONE-TWO PUNCH
LONG DISTANCE CANCER ADVISORY SERVICES
US GENOMIC TESTING
Confidential and for discussion only
15
05/01/2023
• US based Cancer Institutions are sine qua
non the leaders in Cancer Care
• Expanding this intellectual capital
overseas is a challenge, but one that, if
resolved, would support both their Hippocratic
and institutional development goals
• Genomic Testing is a growing frontier and one that US Cancer
Centers are developing aggressively
• US Genomic Testing labs are focused on the US Market, but their capabilities and expertise could jumpstart an improvement in global cancer care
• Limitations in outreach, operations, fulfillment and payment (insurance) mechanisms limit their ability to grow overseas
• The support of US Cancer Centers would make their services more accessible and useable
The Challenge
Expandable to Neuro and Cardio from Onco
05/01/2023Confidential and for discussion only 16
WE BELIEVE THE CHALLENGE IS TO GET THE MOST OUT OF ADVANCED GENOMIC TESTING BY BRACKETING WITH A SERIES OF SERVICES THAT MAKE IT MORE ACCESSIBLE AND USEFUL TO INTERNATIONAL MDS AND PATIENTS
Financial, Marketing
and Logistics Support
Genomic Test
The Challenge
05/01/2023Confidential and for discussion only 17
The Target MarketWho the Consumers are in Lat Am
05/01/2023Confidential and for discussion only 18
LATIN AMERICA PRESENTS MANY CONDITIONS THAT MAKE IT APPROPRIATE TO LAUNCH A PROGRAM LIKE TAK’S
MD’s have expressed a demand for the Service due to lower level of familiarity with Genomic Testing
High economic growth centered around an emerging middle class Tight links with the US and brand recognition of its medical centers Private medical care is available for Medium and Higher income
individuals Age pyramid trending towards the peak Cancer years – 40+ Growing private insurance sector Fairly open in foreign exchange conversion, although with roadblocks
and hurdles
The Target Market
05/01/2023Confidential and for discussion only 19
LATIN AMERICA PRESENTS A CONSOLIDATING AND RAPIDLY AGEING MIDDLE CLASS WHICH IS OUR TARGET MARKET
The Target Market
05/01/2023Confidential and for discussion only 20
OUR TARGET MARKETS IN LATAM START WITH PREPAY AND THOSE COVERED BY INSURANCE AND WILL EVENTUALLY GROW TO THE PUBLIC SECTOR
Current Sector- Prepay/Selfpay
Clients
Target Sector- those with Insurance Coverage
Final Sector – Public Sector Clients
Around 3-5% or 18-30MM people
Around 15-18% or 100MM people
Around 80% or 500MM people
Have the financial wherewithal, but lack the value chain support needed to utilize these services
Could access these services with insurance coverage and value chain support
Could access these services with Public Sector help and value chain support
The Target Market
05/01/2023Confidential and for discussion only 21
LATIN AMERICA HAS A CLASS OF HIGHER NET WORTH INDIVIDUALS THAT WOULD PAY TO USE THESE GENOMIC TESTS AND US CANCER ADVISORY SERVICES; THEY COMPRISE 3-5% OF THE TOTAL OR 18-30MM OF THE 600 MM POPULATION
Analisis Lambda International Consultants, Data base from respective sources in each country
Using 0.15% cancer incidence rate, this represents 30-50,000 cancer cases per yearPrePay individuals
have been hampered by the logistics, fulfillment and
integration of multiple players required to
access services, irrespective of
payment capabilities
The Target Market
05/01/2023Confidential and for discussion only 22
LATIN AMERICAN PRIVATE HEALTH INSURANCE COVERS 100MM PEOPLE – 4X TO 6X MORE
Latin American Private Health Insurance is a USD 38BN Industry covering 100 MM people
Reaching 1% of insured would be 1MM people
Country% covered
Private insurance
Population MM
Number Covered MM 1% of Insured
Argentina 10% 40 4.00 40,000 Brasil 30% 190 57.00 570,000 Chile 16% 17 2.70 27,000
Colombia 35% 45 15.53 155,250 Mexico (1) 8% 110 8.80 88,000
Peru 4% 30 1.05 10,500 Venezuela 9% 30 2.78 27,778
Total 20% 462 91.85 918,528 Other areas 10% 150 15.00 150,000
Total Latam-C 17% 612 106.85 1,068,528 Source: Mapfre Insurance, Latin American Health Systems, 2009;(1) http://www.facmed.unam.mx/sms/temas/2010/03_mar_2k10.pdf Analysis by Lambda International Consultants
Insurance companies have not had an external partner to support them
in integrating the logistics, fulfillment and integration of multiple
players required to access services,
irrespective of payment capabilities, in addition
to the outreach and other support functions
required for international programs
The Target Market
05/01/2023Confidential and for discussion only 23
WE ESTIMATE THAT 6MM IS THE ADDRESSABLE AND CAPTURABLE MARKET FOR AN INSURANCE PROGRAM OFFERING GENOMIC TESTING AND US CANCER SUPPORT= 1% OF THE POPULATION
High Net Worth Insured Middle Class Insured01020304050607080
30
70
3 3
27
67
Capturable Market
Total MM Genomic Insurance Buyers Non Buyers
05/01/2023Confidential and for discussion only 24
ENGAGING THE PUBLIC SECTOR WOULD ULTIMATELY ACCESS MOST OF LATIN AMERICA’S POPULATION IN THIS INITIATIVE
Percentage of the Population in LatAm
Self Pay Insurance Public Sector
• Public Sector users have neither insurance nor PrePay-SelfPay capabilities
• Nevertheless, they are a huge number and incorporating them into a program would reduce cost and absorb fixed costs enormously
The Public Sector is a more long term goal, but
once the value and feasibility of these
Programs are demonstrated in Private Sector Initiatives, it is
certain that a percentage of the Public
Sector will move to adopt similar offerings
The Target Market
05/01/2023Confidential and for discussion only 25
Our ProposalWhat we Propose to the Consumers in Lat Am
05/01/2023Confidential and for discussion only 26
OUR PROPOSAL IS TO DEVELOP AN INSURANCE BASED SYSTEM OF COVERAGE WHICH WILL ALSO SUPPORT SELFPAY/PREPAY AND ULTIMATELY LEAD TO PUBLIC SECTOR ADOPTION
Prepay TAK SUPPORT PLATFORM MEDICAL , FINANCIAL INSTITUTIONS AND MDs
Insurance TAK SUPPORT PLATFORM BROKERS, INSURANCE COMPANIES, AFFILIATED MDs
Public TAK SUPPORT PLATFORM PUBLIC SECTOR INSTITUTIONS
Our Proposal
PAYMENT CHANNEL EXECUTION/FULFILLMENT OUTREACH
FIRST PHASE
LATER PHASE
Confidential and for discussion only 27
OUR SUPPORT PLATFORM WOULD USE INFORMATION TECHNOLOGY TO INTEGRATE THE DIFFERENT PLAYERS STARTING AT THE INSURANCE COMPANIES PLUS PROVIDE A SECURE DATA EXCHANGE, TRACKING AND PAYMENT PLATFORM
05/01/2023
Our Proposal
DATA EXCHANGED• Patient information• Payor information• Logistics information
INS CO.
PAYORS DATA EXCHANGED• Test information• DDS/Medical opinion information• Patient Progress information
TRANSLATIONSERVICES
PAYEES
WE PROPOSE TO OFFER AN INTEGRATED LEVEL OF SERVICE TO MD’S AND PATIENTS IN LATAM-C TO FACILITATE ACCESS TO US CANCER CENTER SUPPORT AND GENOMIC CANCER TESTING
Leading Cancer Center Long Distance Cancer Advisory Services and
Consultations1. PreTest Long Distance Cancer
Advisory Services for Patients in stages I-IV
1. Prior to the execution of Molecular Diagnostic tests
2. Could include genetic test for inherited risks
2. PostTest Long Distance Cancer Advisory Services for Patients in stage IV
1. Following the execution of Molecular Diagnostic tests
Molecular Diagnostic Laboratory advisory and support
1. Send biopsies and samples for laboratory work in US at Molecular Health or other labs
1. Molecular Health would be the supplier of choice for genomic analysis, but pursuant to local MD selection and approval
2. Support in logistics and processing3. Translation of laboratory results4. Secure platform for data transmission5. Oncological review of genomic test results,
1. TAK’s pool of top oncologists would supply a review of the test results providing Diagnostic Decision Support and orientation in terms of Cancer Management for the patient linking test results with patient EMR
6. The program is also investigating different value added financial options, apart from basic insurance coverage; these include:
1. Support in FOREX conversions if needed2. Financing options for those that want to self pay, not insure
05/01/2023Confidential and for discussion only 28
Our Proposal
Later phases would
include testing for hereditary cancers in Stages I-III
Confidential and for discussion only 29
BASIC SERVICE – GENOMIC TESTING, MOLECULAR DIAGNOSTIC LABORATORY ADVISORY AND SUPPORT – MOSTLY FOR STAGE IV PATIENTS AS REQUESTED BY THE LOCAL MD
US Lab would perform Genomic Testing at its leading edge facility – Molecular Health has been contacted and has a signed LOI to perform this service- others would depend on MD request
Support in logistics and processing ensuring timely delivery of results Translation of laboratory results and management of EMR transmissions via
HIPAA approved channels; hardcopy transmissions via Fedex or other carriers Diagnostic Decision Support, Referential Protocols and Cancer Management
support based on test results (provided by external oncologists) A Portal to assist Patient/MD/Pathologist would agglomerate relevant recent
research in order to assist the patient’s treatment and knowledge Email support for the physician would be maintained for 30 days from date of
delivery of test results Patients prior to Stage IV would not be covered in the Basic Service
Our Proposal
30
PREMIUM– COMPLETE LONG DISTANCE CANCER ADVISORY AT A US CANCER CENTER INCLUDING GENOMIC TEST, ADVISORY AND SUPPORT IF APPROPRIATE AND REQUESTED BY THE LOCAL MD – FOR PATIENTS FROM STAGE I-IV
Patients in Stages I-III would proceed to a Complete Long Distance Cancer Advisory Service focused on advising the local MD with transmission to the USA of all relevant EMR’s and other clinical information for the US MD to make an informed evaluation of the case and alternatives.
Genetic test for inherited predisposition in children of affected parent could be included Were this case to evolve into Stage IV then the local MD would have the option to order a
Genomic Test from one of the labs affiliated with the program- Molecular Health as the preferred provider. Patients that enter already at Stage IV could start at the Molecular Diagnostic testing stage or the Long Distance Cancer Advisory Service
US Lab would perform Genomic Testing at its leading edge facility – Molecular Health has been contacted and has a signed LOI to perform this service as our preferred provider
Support in logistics and processing ensuring timely delivery of results Translation of laboratory results Diagnostic Decision Support, Referential Protocols and Cancer Management support based on test results
provided by external oncologists A Portal to assist Patient/MD/Pathologist would agglomerate relevant recent research in order to assist the
patient’s treatment and knowledge Email support for the physician would be maintained for 30 days from date of delivery of test results
The Complete Long Distance Cancer Advisory could occur before or after the Genomic Tests were in, with timing depending on the results; In some cases it could precede and evaluate the usefulness of genomic tests depending on local MD input.
Confidential and for discussion only
Our Proposal
05/01/2023Confidential and for discussion only 31
OUR SUMMARY OF THE INSURANCE COVERAGE PROPOSED
BASIC SERVICEStage IV
onlyGenomic Test
Diagnostic Decision Support
PREMIUM SERVICEStage I-IV
at discovery
US CANCER CENTER ADVISORY
SERVICE
Our Proposal
Diagnostic Decision Support
GENOMIC TEST
TIME LAPSE UNTIL STAGE IV *
* IF NO STAGE IV, GENOMIC TEST AND DDS REPLACED BY TWO FOLLOW ON US CANCER CENTER ADVISORY SERVICES; IN Stage IV TEST MAY PRECEDE ADVISORY SERVICE
US CANCER CENTER ADVISORY
SERVICE
OPTIONAL CASH PURCHASE
MH as preferred provider
MH as preferred provider of Genomic Test; Diagnostic Decision Support performed by one of the leading US Cancer Centers
STRUCTURED INSURANCE PRODUCT OFFERINGS – ESTIMATED PRICE TO CLIENT IS AFFORDABLE TO THE MIDDLE CLASSLatin America Standard Pricing(Family=4 people)
Insurance Coverage USD(Nominal Value)
Coverage Starts at
Genomic Test
Diagnostic Decision Support via US Oncologist
No of distance consultationsWith US Cancer Center
Estimated annual Premium(actual figures may vary)
Basic Individual
USD 12,500
Metastasis (Stage IV)
None USD 35
Basic Family
USD 12,500
Metastasis (Stage IV)
None USD 130
Premium Individual
USD 17,500
Discovery (Stage I,II or III)
One Pre Test
USD 70
Premium Individual
USD 17,500
Discovery(Stage IV)
One Post Test
USD 70
Premium Family
USD 17,500
Discovery (Stage I,II or III)
One Pre Test
USD 200-225
Premium Family
USD 17,500
Discovery (Stage IV)
One Post Test
USD 200-225
Our Proposal
Nominal Value is for Consumer evaluation only; Basic and Premium have costs defined on a per Company basis
05/01/2023Confidential and for discussion only 33
THE USD 200 COST PER FAMILY IS LOW COMPARED TO TOP LEVEL LOCAL AND GLOBAL/INTERNATIONAL MEDICAL INSURANCE COSTS
AVERAGES BASED ON INTERNATIONAL AND LOCAL COVERAGE FOR FAMILY OF 4
Confidential and for discussion only 34
OUR PROGRAM TO COMPLEMENT INSURANCE WAS WELL RECEIVED IN LATAM-LAUNCH IS IMMINENT TestAnalytika has launched its first policy into Latin America and the
Middle East via Redbridge It expects to launch the second policy via a grey market broker in Ecuador
in 35 days; TestAnalytika has presented this program to insurance companies in
LatAm with strong response TestAnalytika is also working with local financial institutions to
establish a payment plan for those who do not have insurance coverage Part of this financing may be covered by credits in life insurance policies
Employee Benefit Plans have also emerged as a recent target of interest
Our Proposal
WE HAVE CONTACTED MANY OF THE PREMIER US MEDICAL CENTERS FOR SUPPORT
Leading Cancer Center Long Distance Cancer Advisory Services and
Consultations1. Memorial Sloan Kettering (Oral
agreement in place with email confirmation)
2. UM Sylvester Cancer Center (Oral agreement- contract underway)
3. UC San Diego (In talks scheduled for Sept 15)
4. Penn Medicine (Oral agreement)5. Memorial Health System, FL (In
talks)6. MD Anderson (Oral agreement)7. UC San Francisco (Visit
scheduled for Sept)
Molecular Diagnostic Laboratory advisory and support
1.Signed LOI with Molecular Health; Foundation Medicine, others under review
2.Access if needed Genomic Labs at Memorial Sloan Kettering, MD Anderson, UPenn, UMiami
05/01/2023Confidential and for discussion only 35
Our Proposal
05/01/2023Confidential and for discussion only 36
Go To MarketHow to reach the Consumer
05/01/2023Confidential and for discussion only 37
INSURANCE COMPANIES IN LATAM ARE CLEARLY IDENTIFIED AND TARGETED
Go to Market
These companies could be targets for
taking on risk themselves or
fronting underwritten policy
05/01/2023Confidential and for discussion only 38
OUR INSURANCE MARKET LOCAL PARTNERS ARE SOLID FIRMSCOUNTRY GROUP OBSERVATIONS
Mexico MASA/others pending
Third generation insurance executives invoicing over USD 50MM in premiums with top level access to all insurance companies
Brasil TBD In conversations with JLT, Marsh, other major groups to complete alignment
Colombia Vista Financial and Consulting
Boutique financial advisory firm that includes the ex COO of Liberty Mutual Europe; also ex CEO of LM Venezuela
Peru F4SI/others Regional foundation focused on Healthcare and Education initiatives; participating as a JV partner focused on Public sector
Ecuador PROANO Multiple allies among the top firmsVenezuela MaKler Strong local company with top flight
clientbase
Go to Market
05/01/2023Confidential and for discussion only 39
OUR WORKING RELATIONSHIPS ARE AIMED AT MAXIMIZING SALES AND MINIMIZING INVESTMENTS TAK has proposed a joint profit sharing relationship with the local
partners, reducing our share of capital expense and increasing traction in the markets They share with us the insurance company commissions, in exchange for
supervision of the day to day relationship and the sales and marketing efforts
The S&M efforts would be paid for out of the 5% S&M fee The local partner would also get a commission on each test sale resulting
from the insurance company relationship Local Partner would be lead broker, supervising other brokers and leading
Sales and Marketing and Medical Education activities
Go to Market
05/01/2023Confidential and for discussion only 40
A KEY SALES AND MARKETING WILL BE TO INCREASE LATAM MD’S AWARENESS AS TO GENOMIC TESTING AND THE ADVANTAGES OF US CLINICAL SUPPORT
Go to Market
25%
57%
18%
What percentage of patients would you perform genomic tests on?
n=160 US MD's
Over 90%
In between
Less than 10%
Even in the US there is an
enormous gap in awareness of Genomic
Testing
05/01/2023Confidential and for discussion only 41
OUR MARKETING STRATEGY IS A MIX OF TRADITIONAL AND SOCIAL MEDIA USING 5% OF INSURANCE PREMIUMS COLLECTED
25%25%25%
20%
5%
TAK's Proposed Market-ing Budget
Trad. DetailingE-DetailingB2C Social MediaEvents & Hospi-talsTrad. Media
Go to Market
Trad.
Detailin
g
E-Deta
iling
B2C So
cial M
edia
Events
& Hospita
ls $-
$2,000 $4,000 $6,000
Cost per Medical Center Per Year
05/01/2023Confidential and for discussion only 42
Business PlanWhat the business would look like
05/01/2023Confidential and for discussion only 43
FOUR CHANNELS ARE AVAILABLE FOR US WITHIN INSURANCE AND RELATED FIELDS
Traditional Onshore
Insurance Channel
(via Straight Risk or
Fronting +Reinsurance)
Traditional Offshore Grey
Market Companies
Employee Benefit Plans via Insurance
based packages
Direct to Consumer via Online Access ( onshore or
offshore policy)
Business Plan
05/01/2023Confidential and for discussion only 44
OUR BUSINESS PLAN FOR A LOCAL PARTNER LIKE YOU REVOLVES AROUND THESE AREAS
Business Plan
1. Sell within and to your existing client base1. Link up with a local onshore company that wants to develop or just front
the product2. If legally viable, sell an offshore product as “medical travel insurance” –
note that all payments to providers are made in the US, no conflict with local insurance regulators
2. Develop international executive benefits plan business through distribution partners and existing corporate clients
1. May be via a Captive Insurer for tax benefits2. May be via an offshore “Mutual Insurance Company” to reduce costs
3. Sell directly into new areas by use of internet and other channels
05/01/2023Confidential and for discussion only 45
OUR CONSERVATIVE ESTIMATE FOR ARGENTINA IS AROUND 15-20,000 PEOPLE COVERED- REACHING 1% OF THE POPULATION WOULD BE 400,000 PEOPLE Covering 5,000 families at USD
225/family means over USD 1,100K premiums
Local Partner take of 20% is over USD 220K
Additionally, 5% commission on services provided upon cancer incidence should generate USD 20K more in fees
Business Plan
Year 1 Year 2 Year 302000400060008000
10000120001400016000
People Covered
People
05/01/2023Confidential and for discussion only 46
TeamWho would run the program
05/01/2023Confidential and for discussion only 47
LIN GIRALT Lin Giralt is Managing Director of Lambda International Consultants, LLC, Houston,
TX and Adjunct Professor, Jones Graduate School of Business at Rice University. Lin has over 30 years work experience of which 20 years are in consulting. He started his
consulting career with McKinsey & Company and Booz-Allen & Hamilton leading projects throughout all of Latin America and founded Lambda in 1997. His main focus is corporate strategy, processes, organization and market entry strategies. His focus is on startups, medium sized businesses and how to help them become more competitive in a globalized economy.
In the medical field, Lin designed all the business and commercial processes for a major plastic surgery clinic, reviewed the commercial strategy and logistics for a major pharmaceutical products manufacturer and helped a distributor of prosthetic products segment the market and develop a more effective go to market strategy.
Prior to consulting he served as Operations and Sales Manager for a family owned agribusiness and Construction Manager for a series of office and industrial projects in the US and overseas.
Lin Giralt is Chairperson of the Rice Graduate Alumni Committee and is also former Vice-president of Houston’s MBA Council. In addition to a Rice M. Architecture degree, he holds a B.A. from Duke University and an M.B.A. in Finance and Real Estate from The Wharton School. Married (32 years), two kids, four cats, one dog. He is a Golfer and Squash player, a student of history and military and business strategy
Team
05/01/2023Confidential and for discussion only 48
ZEKE WIMERT Zeke Wimert has been a senior leader at Fortune-500, multinational and
start up technology companies, Zeke has extensive experience as a thought leader and builder of profitable, high profile operations in various industries and markets, both in the United States and Internationally.
He has held senior roles as CEO, COO and Senior Vice President-level assignments at global companies such as National Semiconductor, Motorola and Oracle, as well at successful start up organizations such as Unitools, AboveNet Communications and OptiConnect. His industry expertise spans semiconductors, enterprise software, telecom infrastructure products, high-availability internet networks, and carrier voice and data services.
Over the past seven years as a consultant, he has been actively involved in management and acquisitions of a wide range of companies in the US and internationally, including direct management roles in turnaround situations in exceptionally complex, fast-moving markets.
Zeke Wimert graduated from the United States Military Academy and received a degree in Applied Engineering, followed by a Masters degree in Economics, with honors, at the State University of New York at Stony Brook as well as graduate work in Operations Research and Systems Analysis at Georgia Tech.
Team
Our Team is building up, we hope this presentation clarifies doubts and your organization can join us
05/01/2023Confidential and for discussion only 49
Team
EXECUTIVE TEAM
INSURANCE COMPANIES & BROKERS
US CANCER CENTERS
US GENOMIC LABS