DERMAL FILLERS

OUTLINE - ABSORBABLE POLYACRYLAMIDE

MEDICAL DISCLOSURE:

• Dr. Patrick J. Treacy is a Cosmetic Doctor registered in UK and Ireland

• I have previously been registered in United States, Australia, New Zealand and South Africa.

• I have no financial interest or stock in Syneron

• I receive no additional remuneration for product bought by you after attendance at this lecture.

REPLACE LOST TISSUE REPLACE LOST TISSUE VOLUMEVOLUME

• NOSE TO MOUTH LINES

• LIP AUGMENTATION

• LIPSTICK LINES

• MARIONETTE LINES

• CHEEK VOLUME

• FOREHEAD LINES, FROWN LINE

• CROWS FEET

COLLAGENCOLLAGEN

• CREATED THE MARKET • COSMETIC TREATMENTS NO LONGER THE

DOMAIN OF THE RICH AND FAMOUS• SAFE, AFFORDABLE, AVAILABLE• ALLERGY TO COLLAGEN• COLLAGENASES INDUCED – DURATION OF

ACTION SHORTER AND SHORTER• PATIENTS DEMORALISED – STOP

TREATMENT

HISTORY OF DERMAL FILLERS

• REPLACE LIKE WITH LIKE – COLLAGEN

• REPLACE LIKE WITH SIMILAR – HYALURONIC ACID

• REPLACE LIKE WITH ARTIFICIAL – NEWFILL

• SOPHISTICATION OF ARTIFICIAL FILLERS – ABSORBABLE POLYACRYLAMIDES

POLYACRYLAMIDE

• OCULAR IMPLANTS

• CONTACT LENSES

• ARTIFICIAL TEARS

• SUTURE MATERIAL – CARDIAC MICROSURGERY

• WATER FILTRATION

• WINE FILTRATION

OUTLINE = ABSORBABLE OUTLINE = ABSORBABLE POLYACRYLAMIDEPOLYACRYLAMIDE

• WEAK ESTER BONDS INSERTED INTO POLYACRYLAMIDE (PATENTED)

• METABOLISED BY TISSUE ESTERASES• SMALLER FRAGMENTS OF POLYACRYLAMIDE

ELIMINATED VIA BILE• PREDICTABLE BREAKDOWN; NON-TOXIC

METABILITES• CAN DEFINE LONGEVITY OF PRODUCT• CAN INJECT AT ALL TISSUE LEVELS

INSERTION OF WEAK ESTER INSERTION OF WEAK ESTER

BONDS: DEFINING LENGTHBONDS: DEFINING LENGTH

METABOLISM OF WEAK ESTER METABOLISM OF WEAK ESTER BONDS BY ESTERASESBONDS BY ESTERASES

THE OUTLINE FAMILYTHE OUTLINE FAMILY

• OUTLINE ORIGINAL

• OUTLINE ULTRA

• 150,000 SYRINGES IN 5 YEARS

OUTLINE ORIGINALOUTLINE ORIGINAL

• HALF LIFE 2 YEARS

• CLINICAL RESULTS 1 YEAR

• NOSE TO MOUTH LINES

• LIPS, LIPSTICK LINES

• MARIONETTE LINES

• CHEEK AUGMENTATION

• (FOREHEAD LINES, FROWN LINE)

• MID DERMIS; 30g NEEDLE

OUTLINE ORIGINAL 0, 4 WEEKS, 6 MONTHS0, 4 WEEKS, 6 MONTHS

FROWN LINE; 0 AND 1 YEARFROWN LINE; 0 AND 1 YEAR

OUTLINE ULTRA

• T ½ 5 YEARS

• CLINICAL RESULTS 2-3 YEARS

• DEEP LINES AND FOLDS

• NOSE TO MOUTH LINES

• POOR QUALITY LIPS

• SUBDERMAL INJECTION 27G

• BASE FOR ORIGINAL

INJECTION TECHNIQUESINJECTION TECHNIQUES

• ALWAYS RETROGRADE TUNNELLING

• MINIMISE PUNCTURE HOLES

• DO NOT OVER FILL

• FLATTEN GENTLY; DO NOT MASSAGE

• AVOID UV AND ALCOHOL 24 HOURS

• REPEAT 4 WEEKS + IF NECESSARY

CONTRAINDICATIONSCONTRAINDICATIONS

• AS FOR ALL INJECTABLE FILLERS:– ALLERGY (SKIN TEST AVAILABLE)– IMMUNOSUPRESSION– ACTIVE INFECTION– PREGNANCY, LACTATION– AUTOIMMUNITY – HERPES SIMPLEX VIRUS – ORAL ANTIVIRAL ESSENTIAL

FOR LIPS – CAUTION

• LET OTHER FILLERS GROW OUT• AVOID ARTECOLL SITES • SEVERELY ALLERGIC PEOPLE• SEVERELY ILL PEOPLE• WARFARIN OR OTHER ANTICOAGULANT TREATMENT• ASPIRIN, NSAIDS

OUTLINEOUTLINE

• VERSATILE RANGE OF FILLERS

• LONG LASTING

• NON-PARTICULATE, PREFILLED SYRINGE, CONSTANT VISCOSITY

• INJECT AT ALL LEVELS

• 30G NEEDLE

• ROOM TEMPERATURE

• SWELLS 3 HOURS ONLY

OUTLINE

• GOOD COST:BENEFIT RATIO

• GOOD SAFETY PROFILE

• EASY TO STORE AND TO USE

• 1ML AND 0,5ML SYRINGES

• PATIENT HAPPY

• DOCTOR HAPPY