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Evening Primrose Oil Prepared by : KESHANTHINI D/O RAMACHANDRAM

Evening primrose oil

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Page 1: Evening primrose oil

Evening Primrose

Oil

Prepared by : KESHANTHINI D/O RAMACHANDRAM

Page 2: Evening primrose oil

Evening Primrose Oil

Botany

Oenothera biennis., a wildflower/weed on the East USA coast

The seed is pressed to yield an oil

History

Many native American uses for the plant

Recent years have focused on the uses of the seed oil

Page 3: Evening primrose oil

Chemistry• Seed contains about 14% oil of which half is

gamma linolenic acid (GLA); this is a omega –6 essential fatty acid;

• note: omega –3 fatty acids are present in fish oils and flaxseed oils and have different uses (e.g. lower cholesterol and risk of cancer)

• GLA is a precursor to prostaglandin E1 which modulates (reduce) inflammation

• Other rich sources of GLA are borage seed oil (20%GLA) and black currant oil (15% GLA)

Page 4: Evening primrose oil

PHARMACOLOGY OF GLA

• GLA is precursor to several prostaglandins and leukotrienes

that influence pain and inflammation• The idea is to “flood the system” with precursor to enhance

synthesis.• Linoleic acid (LA) is an essential amino acid widespread in

our diet• GLA is formed from linoleic acid and is not found in

common foods

Page 5: Evening primrose oil

USES OF GLA AND EVENING PRIMROSE OIL

• Cyclic mastalgia• Premenstrual Syndrom (PMS)• Diabetic neuropathy• Vitamin E• Eczema• Arthritis, fatigue, digestive, asthma, weight

loss, and many others

Page 6: Evening primrose oil

CAN YOU GET EPO NATURALLY FROM FOOD?

GLA, is the active ingredient in EPO, can be found in small amounts in a variety of food sources. However it is most concentrated in plain oils such as epo and borage oil.

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RISK FACTOR OF EPOMost people will tolerate EPO without complications.But keep in mind that there have been reports of side effect such as:

Headaches Stomach upsetNausea Increase the risk of bleeding among people who take

anticoagulant and antiplatelet medication.Raise risk of seizures as well as serious nausea and

vomiting for people taking a class of drug knows as phenothiazines. These drug used to treat psyschotic disorder.

Page 8: Evening primrose oil

RISK OF TAKING EPO? CONTINUED…

• People should be especially cautious about taking EPO if they have:

-Bleeding disorder -Seizure disorder

• People who take medication to low blood pressure, EPO may cause further drop in pressure.

• Pregnant women should not take EPO cause of the potential for complications.

Page 9: Evening primrose oil

BENEFITS OF EPO TO WOMEN

֎ EPO treat the symptoms of PMS because of its essential fatty acid contents.

֎ Getting enough omega-6 fatty acids(LA & GLA), Support overall hormonal

function within the body. Reduce PMS symptoms Create a healthy

environment for contraception

Help to loss weight Produce balanced hormones.

Page 10: Evening primrose oil

֎ Omega-6 fatty acids that are found in EPO are necessary for production & synthesis of prostaglandin E.

֎ Prostaglandins helps to control the regulation of hormones & manage the proper cell growth.

֎ EPO use to prepare the cervix for labor.

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֎ Omega-3 fatty acid (GLA)

Increase the production of cervical mucus.

Cervical fluid is vital for allowing the sperm to swim freely through the cervix.

Page 12: Evening primrose oil

֎ Omega-6 fatty acids that are present in EPO help

Regulate your hormone

levels & cure hormonal acne issues.

It also play a role in cell structure, improving nerve fx & promoting skin elasticity.

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֎ Essential omega-6 fatty(GLA) can be highly effective in the fight against hair loss.

Female hair loss generally due to:

o Stresso Hormone imbalance o Thyroid conditionso Toxic exposure

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֎ EPO treat skin conditions such as:֎ Eczema֎ Psoriasis ֎ Atopic dermatitis

֎ Help with age-related structural & fx changes in skin tissues such as:֎ Redness֎ Firmness֎ Roughness

Page 15: Evening primrose oil

EPO treat:

֎ Rheumatoid arthritis

֎ a significant improvement of disease-related symptoms, including pain & morning stiffness .

(94% who got EPO reported)

Page 16: Evening primrose oil

֎ EPO treat hormonal issues.

֎ Taking EPO + (Fish Oil & calcium), seems to:

Decrease bone loss Increase bone density

In elderly people with osteoporosis

Page 17: Evening primrose oil

EPO BRANDS THAT AVAILABLE IN BEYOND PHARMACY

҉H Mega Live҉H Nova҉H eurobio҉H Kordel’s҉H Blackmores

halal certified.

Page 18: Evening primrose oil

MEGALIVE {EPO} Ingredients :

• EPO (10% GLA) 1200mgequiv. GLA 120mg

• Vitamin E 11.5mgequiv. to d-a- Tocopherol 10mgequiv. to Natural vitamin E 15 IU

Dosage : 1 to 2 cap to take daily with meal.

1 Box contain 30 capsules.

Source of gelatin : Bovine

Manufacture in NEW ZEALAND

Repacked by : White Heron Pharmaceutical sdn.bhd.

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NOVA {EPO}Ingredients :

• EPO (10% GLA) 1000mg

Dosage : 1 to 2 cap to be taken daily after meal.

1 Box contain 100 capsules.

Source of gelatin : Bovine

Manufacture & Distributed by Product Registration Holder : Nova Laboratories Sdn.Bhd.

EPO is made from cold-pressed seeds. It contain rich natural

source of Gama Linolenic Acid (GLA) &

Linolenic Acid (LA) which are know as

Omega 6. These essential fatty acid are importance for

maintenance of good health.

Page 20: Evening primrose oil

Eurobio {EPO}Ingredients :

• Cold Pressed EPO (10% GLA) 1000mg

• Vitamin E 7.5iu

Dosage : 1 to 3 cap to be taken daily after meal.

1 Box contain 120 capsules.

Source of gelatin : Vegicap

Made in Australia by : Catalent Australia Pty Ltd

Imported by : Eurobio Sdn. Bhd.

Repacked by : Prime Pharmaceutical Sdn.Bhd

Distributed by: Zuelling Pharma Sdn.Bhd.

Page 21: Evening primrose oil

Kordel’s {EPO}Ingredients :

• EPO (10% GLA) 1200mgequiv. GLA 100mg

Dosage : 1 to 3 cap to be taken daily after meal.

1 Box contain 150 capsules.

Sources of gelatin : vegicap

*Suitable for vegetarians

Manufacuture by : Catalent Australia Pty Ltd

Product owner/marketing Authorization Holder (MAH)

Repacked by : Vitaco Health (NZ) Ltd

Page 22: Evening primrose oil

Blackmores {EPO}Ingredients :

• EPO (10% GLA) 1200mgGLA 100mgLA 650mg

Dosage : 1 to 3 cap to be taken daily with meal. Recommended to children (6 – 12 years).

1 Box contain 100 capsules.

Source of gelatin : Bovine• cold-pressed

Imported by : Blackmores (Malaysia) Sdn.Bhd.

Distributed by: Zuelling Pharma Pte.Ltd.

Manufacture by : Catalent Australia

Packed by : Blackmores Ltd, 20 jubilee Avenue, warriewood NSW 2112 Australia

Page 23: Evening primrose oil

Blackmores {EPO + FISH OIL}Ingredients :

• Natural Fish Oil 500mgApproximately equivalent to :

Omega 3 marine triglycerides 150mg as:-Eicosapentaenoic acid (EPO) …90mg-Docosahexaenoic acid (DHA) …60mg

• EPO 500mg-GLA 5% 50mg

Dosage : 1 to 3 cap to be taken daily with meal. Not recommended to children under 12 years.

1 Box contain 120 capsules.Source of gelatin : Bovine• cold-pressed

Manufacture by Catalent Australia

Packed by : Blackmores Ltd, 20 jubilee Avenue, warriewood NSW 2112 Australia

Imported by : Blackmores (Malaysia) Sdn.Bhd.

Page 24: Evening primrose oil