ENVIROPRENEURS:

A Model for implementing Green Chemistry

Nitesh H. MehtaFounder DirectorNewreka Green Synth Technologies Pvt. Ltd.Mumbai, India

nitesh.mehta@newreka.co.in

Universities:1. Limitations to

Customize, Scale-up & Commercialize

2. Limitations to Market their Innovations

Industry:1. Profit Driven Approach2. Limitation to approach

& define their problems3. Mindset of not investing

on Green R&D

Common Man & Society:

1. Lack of Awareness2. Mindset of not investing

on Education & Research

Govt. Bodies & NGO’s:1. Formulations of practical

policies.2. Carrot & Stick Approach3. Limitations of paperwork

& bureaucracy

Overview : The Gaps

Universities:1. Limitations to

Customize, Scale-up & Commercialize

2. Limitations to Market their Innovations

Industry:1. Profit Driven Approach2. Limitation to approach

& define their problems3. Mindset of not investing

on Green R&D

Common Man & Society:

1. Lack of Awareness2. Mindset of not investing

on Education & Research

Govt. Bodies & NGO’s:1. Limitations of

paperwork & bureaucracy

2. Carrot & Stick Approach

Enviropreneurs

“Enviropreneurs” – A Possible Bridge

Enviropreneurs = Environment + Entrepreneurs

Enviropreneurs :

Their View : Environment is an Asset not a Problem.

Their Qualities : “Passion” of an Environmentalist & “Spirit of Adventure” of an Entrepreneur.

Their Business Model : Long Term Sustainable Solutions

Their Goals : Make Money & also Produce benefits for the Environment

“Enviropreneurs”

Entrepreneur or Businessman

Scientist or Researcher

Chemist or a Chemical Engineer

Academician

Any one of us

Enviropreneur – A Mindset, A way of thinking

Who are “Enviropreneurs”?

Founders Team of Technocrats from IIT Bombay passionate about Nature

Foundation Principles of Green Chemistry, Green Engineering & Enviropreneurship

Knowledge Base & Over 40,000 experiments conducted by

Experience a dedicated team of 50 Chemists & Chemical Engineers.

Service Customized & Sustainable Solutions to

reduce E-FACTOR*

* E-FACTOR = kgs waste generated per kg product

Newreka as “Enviropreneur”

All Unit Processes use H2O / Solvent as a Reaction Medium or Extraction Medium

Reduction, Condensation, Nitration, Diazotization, Hydrolysis, Methylation, etc.

Use is spread across all Industrial Sectors Pharma, Dyes, Pigments, Specialty & Fine Chemicals, Agro, etc.

High Volume Products generate huge quantities of waste

like H-Acid, DASDA, Paracetamol, Phenylephrine, Pigment CPC, Violet23, Pendimethylene..

Focus: Reducing E-FACTOR (Recycle of Aqueous & Solvent Effluent

Streams)

Average Composition of Reaction Mass

Solvent & Water contribute more than 90% of the Reaction Mass

Source Data: ACS GCI Pharmaceutical Roundtable benchmarking exercise 2007

Average composition of Effluents will be similar.

Recycle of Water & Solvent can take care of 90% of problem.

“Prevent Waste: Design chemical syntheses to prevent waste, leaving no waste to treat or clean

up” 1st Principle of Green

Chemistry

DRUG : Anti – Retroviral Drug CUSTOMER : A fast growing Indian Pharma Company

CONVENTIONAL SYNTHETIC CHEMISTRY PROCESS

E-Factor 32 38 28 4

Effluent 1920 TPA 2280 TPA 1680 TPA 240 TPA (for 60TPA plant)

GREEN CHEMISTRY SOLUTION BY NEWREKA

E-Factor 6 6 1 4Effluent 360 TPA 360 TPA 60 TPA 240 TPA

Stage IIIChlorination

Stage IVReduction

Stage VStage IINitration

Stage IDiazo. & Hydrolysis

Stage VI

Stage IINitration

Stage IIIChlorination

Stage IVReduction

Stage IDiazo &Hydrolysis

Stage VIStage V

Case Study: Reducing E-Factor & Improving Yield

Stage I : Diazotization - Hydrolysis

20% higher yield (higher conversion & selectivity, recycle of aq. acidic stream)

Decreased fresh water consumption in process by recycle of ML.

Elimination of one of the solvents from the process.

Replacing a Class I solvent with a safer solvent.

Stage II : Nitration

163% higher yield (higher conversion & selectivity, recycle of aq. stream).

Decreased fresh water consumption in process by recycle of ML.

Replacing a Class I solvent with a safer solvent.

Stage III : Chlorination

16% higher yield (increased conversion & selectivity).

Decreased fresh water consumption in process by recycle aq. acidic stream.

Replaced one solvent with another which is more effective & much safer to handle.

Recovery & reuse of some of the raw materials.

Stage III : Reduction

23% higher yield (increased conversion & selectivity).

Eliminated use of two solvents from the process by using Water as the reaction & extraction medium

Decreased fresh water consumption in process by recycle of neutral ML.

Safer process since solvents are eliminated & high pressure reaction replaced by atmospheric pressure process.

Case Study: Reducing E-Factor & Improving Yield

E - Factor for Manufacturing Sectors

Sector E - Factor Product Tonnage

Oil Refining ≤ 0.1 106 - 108

Bulk Chemicals 1 – 5 104 – 106

Fine Chemicals 5 – 50+ 102 – 104

Pharmaceuticals 25 – 100+ 10 - 103

Source: R A Sheldon

E - Factor = Total mass of λmaterials required to produce 1kg product

(mass intensity) – 1

fresh

Industries: Pharma, Dyes, Pigment, Agro, etc.

e.g. Pharma – 1 billion kgs per annum of Drugs

Products: huge volumes & huge E-Factors

Chemistries: Friedel Craft, Sulphonations, etc.

Effluent Streams: Solid, Liquid, Gaseous

Opportunities for Enviropreneurs

Universities Industries

Common Man & Society

Govt. Bodies & Financial Institutions

Enviropreneurs

IP & Knowledge

Empowerment & Support

Selling Ideas & Scale-up

Sustainable Solutions

Investment on R&D & Value for Solution

Investments & Incentives

Good ROIEmployment & Healthy Living

Enviropreneurs : Model for implementing Green Chemistry

Thank You

&

Wish all of You a

“Greener Future”from

Team Newreka