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Herbal cure for Ebola virus disease (EVD) Presented by Dr. Sudhakar Kokate Director PPRC, India

Ebola

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Ebola outbreak instigates all scientists and researchers to make a detailed study and provide some solutions for the discovery of a cure for human welfare. This presentation is such an attempt trying to make a difference in the research and development of Ebola virus disease

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Page 1: Ebola

Herbal cure

for

Ebola virus disease (EVD)

Presented by Dr. Sudhakar KokateDirector PPRC, India

Page 2: Ebola

Dedicated

to

Ebola affected patients

all over the world

PPRC/INDIA 01

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What is Virus?

A small infectious agent that replicates only inside

the living cells of other organisms

Infect all types of living forms

Also known as Virions

Of different shapes, size 1/100th of average bacterium

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What is Virus?

They are made up of:

1. DNA/RNA, long molecules carrying genetic

information

2. Protein

3. An envelope of lipids

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Important viral diseases

PPRC/INDIA 04

Influenza Small pox Hepatitis

Hepatic cirrhosis Kaposi sarcoma AIDS

Measles Pneumonia Bronchitis

Common cold Rabies Chickenpox

Herpes zoster EVD Viral meningitis

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Ebola virus (EBOV)

Most dangerous of the known viruses

Named as Ebola in earlier Zaire (2010)

Family – Filoviridae

Species – Zaire ebolavirus

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Ebola virus disease (EVD)

Severe disease, fatality rate upto 90%

Primarily in villages of Central-West Africa

Human to human transmission

First appeared in 1976 in Nizara, Sudan and

Yambuku

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Symptoms of EVD

Sudden onset of fever

Intense weakness

Muscle pain

Headache

Sore throatPPRC/INDIA 07

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Symptoms of EVD

Impaired liver and kidney function

Internal and external bleeding in some cases

Vomiting

Diarrhoea

RashPPRC/INDIA 08

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Facts of Ebola

Formerly known as Ebola haemorrhagic fever

Ebola is caused by an RNA virus

Incubation period 2 -21 days

Bleeding is common in later stages

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Types of tests

Antibody: capture enzyme linked immunosorbent

assay (ELISA)

Antigen detection tests

Serum neutralization tests

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Types of tests

Reverse transcriptase polymerase chain reaction

(RT-PCR) assay

Electron microscopy

Virus isolation by cell culture

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Ebola virus disease outbreak

PPRC/INDIA 12

Year Country Cases Deaths% case fatality

1976 Congo 318 280 88

1976 Sudan 284 151 53

1977 Congo 1 1 100

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Ebola virus disease outbreak

PPRC/INDIA 13

1979 Sudan 34 22 69

1994 Gabon - Zaire 52 31 60

1995 Congo - Zaire 315 254 81

1996 Gabon - Zaire 31 21 68

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Ebola virus disease outbreak

PPRC/INDIA 14

2000 Uganda Sudan 425 224 53

2001-2 Gabon - Zaire 65 53 82

2003 Congo - Zaire 202 172 82.2

2005 Congo - Zaire 12 10 83

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Ebola virus disease outbreak

PPRC/INDIA 15

2007 Congo - Zaire 264 187 71

2008 Congo - Zaire 32 14 44

2012 Uganda Sudan 24 17 71

2012 Congo - Zaire 57 29 51

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Types of tests

Reverse transcriptase polymerase chain reaction

(RT-PCR) assay

Electron microscopy

Virus isolation by cell culture

PPRC/INDIA 16

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WHO report

There is no cure for

Ebola Virus Disease (EVD)

No licensed vaccine

No specific treatment available

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Research work

All over the world

Many scientists, research groups are engaged in R&D

about development of drugs, vaccines against Ebola

and other diseases

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U.S. Defense Dept.

spent $140 mn on

Ebola virus disease treatment

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National Agency for food, drug &

control …. Scientific committee

(NAFDAC) claimed in 2013

effective herbs for Ebola virus and othersPPRC/INDIA 20

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Azadirachta indica - Neem

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Allium sativum - Garlic

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Aloe barbadensis – Aloe vera

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Amaranthus yoruba: Green Amaranth

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Carica papaya - Papaya

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Cymbopogum citratus: Lemon grass

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Dioscorea alata – Water yam

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Euphoria hirta – Asthma plant

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Garcinia kola – Bitter kola

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Momordica charantia –Bitter melon

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Psidium guajava - Guava

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Sesamum indicum – Sesame

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Saccharum officinarum - Sugarcane

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Vernonia amygdalina – Bitter leaf

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Zea mays - Maize

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Attention!All Global scientists!!

I suggest following two plants for Ebola :

Tulsi, Ocimum sanctum

Indian curry leaf tree, Murraya koenigii

Do reciprocate: [email protected]

From,

Director, PPRCPPRC/INDIA 36

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Ocimum sanctum - Tulsi

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Murraya koenigii – Indian curry leaf tree

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Thank You !!

“BE WITH US”