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Ebola outbreak instigates all scientists and researchers to make a detailed study and provide some solutions for the discovery of a cure for human welfare. This presentation is such an attempt trying to make a difference in the research and development of Ebola virus disease
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Herbal cure
for
Ebola virus disease (EVD)
Presented by Dr. Sudhakar KokateDirector PPRC, India
Dedicated
to
Ebola affected patients
all over the world
PPRC/INDIA 01
What is Virus?
A small infectious agent that replicates only inside
the living cells of other organisms
Infect all types of living forms
Also known as Virions
Of different shapes, size 1/100th of average bacterium
PPRC/INDIA 02
What is Virus?
They are made up of:
1. DNA/RNA, long molecules carrying genetic
information
2. Protein
3. An envelope of lipids
PPRC/INDIA 03
Important viral diseases
PPRC/INDIA 04
Influenza Small pox Hepatitis
Hepatic cirrhosis Kaposi sarcoma AIDS
Measles Pneumonia Bronchitis
Common cold Rabies Chickenpox
Herpes zoster EVD Viral meningitis
Ebola virus (EBOV)
Most dangerous of the known viruses
Named as Ebola in earlier Zaire (2010)
Family – Filoviridae
Species – Zaire ebolavirus
PPRC/INDIA 05
Ebola virus disease (EVD)
Severe disease, fatality rate upto 90%
Primarily in villages of Central-West Africa
Human to human transmission
First appeared in 1976 in Nizara, Sudan and
Yambuku
PPRC/INDIA 06
Symptoms of EVD
Sudden onset of fever
Intense weakness
Muscle pain
Headache
Sore throatPPRC/INDIA 07
Symptoms of EVD
Impaired liver and kidney function
Internal and external bleeding in some cases
Vomiting
Diarrhoea
RashPPRC/INDIA 08
Facts of Ebola
Formerly known as Ebola haemorrhagic fever
Ebola is caused by an RNA virus
Incubation period 2 -21 days
Bleeding is common in later stages
PPRC/INDIA 09
Types of tests
Antibody: capture enzyme linked immunosorbent
assay (ELISA)
Antigen detection tests
Serum neutralization tests
PPRC/INDIA 10
Types of tests
Reverse transcriptase polymerase chain reaction
(RT-PCR) assay
Electron microscopy
Virus isolation by cell culture
PPRC/INDIA 11
Ebola virus disease outbreak
PPRC/INDIA 12
Year Country Cases Deaths% case fatality
1976 Congo 318 280 88
1976 Sudan 284 151 53
1977 Congo 1 1 100
Ebola virus disease outbreak
PPRC/INDIA 13
1979 Sudan 34 22 69
1994 Gabon - Zaire 52 31 60
1995 Congo - Zaire 315 254 81
1996 Gabon - Zaire 31 21 68
Ebola virus disease outbreak
PPRC/INDIA 14
2000 Uganda Sudan 425 224 53
2001-2 Gabon - Zaire 65 53 82
2003 Congo - Zaire 202 172 82.2
2005 Congo - Zaire 12 10 83
Ebola virus disease outbreak
PPRC/INDIA 15
2007 Congo - Zaire 264 187 71
2008 Congo - Zaire 32 14 44
2012 Uganda Sudan 24 17 71
2012 Congo - Zaire 57 29 51
Types of tests
Reverse transcriptase polymerase chain reaction
(RT-PCR) assay
Electron microscopy
Virus isolation by cell culture
PPRC/INDIA 16
WHO report
There is no cure for
Ebola Virus Disease (EVD)
No licensed vaccine
No specific treatment available
PPRC/INDIA 17
Research work
All over the world
Many scientists, research groups are engaged in R&D
about development of drugs, vaccines against Ebola
and other diseases
PPRC/INDIA 18
U.S. Defense Dept.
spent $140 mn on
Ebola virus disease treatment
PPRC/INDIA 19
National Agency for food, drug &
control …. Scientific committee
(NAFDAC) claimed in 2013
effective herbs for Ebola virus and othersPPRC/INDIA 20
Azadirachta indica - Neem
PPRC/INDIA 21
Allium sativum - Garlic
PPRC/INDIA 22
Aloe barbadensis – Aloe vera
PPRC/INDIA 23
Amaranthus yoruba: Green Amaranth
PPRC/INDIA 24
Carica papaya - Papaya
PPRC/INDIA 25
Cymbopogum citratus: Lemon grass
PPRC/INDIA 26
Dioscorea alata – Water yam
PPRC/INDIA 27
Euphoria hirta – Asthma plant
PPRC/INDIA 28
Garcinia kola – Bitter kola
PPRC/INDIA 29
Momordica charantia –Bitter melon
PPRC/INDIA 30
Psidium guajava - Guava
PPRC/INDIA 31
Sesamum indicum – Sesame
PPRC/INDIA 32
Saccharum officinarum - Sugarcane
PPRC/INDIA 33
Vernonia amygdalina – Bitter leaf
PPRC/INDIA 34
Zea mays - Maize
PPRC/INDIA 35
Attention!All Global scientists!!
I suggest following two plants for Ebola :
Tulsi, Ocimum sanctum
Indian curry leaf tree, Murraya koenigii
Do reciprocate: [email protected]
From,
Director, PPRCPPRC/INDIA 36
Ocimum sanctum - Tulsi
PPRC/INDIA 37
Murraya koenigii – Indian curry leaf tree
PPRC/INDIA 38
Thank You !!
“BE WITH US”