1. Discovering the Other 90%of our Human SuperorganismRemote Video Lecture toThe eResearch Australasia Conference 2014Melbourne, AustraliaOctober 28, 2014Dr. Larry SmarrDirector, California Institute for Telecommunications and Information TechnologyHarry E. Gruber Professor,Dept. of Computer Science and EngineeringJacobs School of Engineering, UCSDhttp://lsmarr.calit2.net1

2. AbstractThe human body is host to 100 trillion microorganisms, ten times the number of cells in thehuman body, and these microbes contain 100 times the number of DNA genes that our humanDNA does. The microbial component of our superorganism is comprised of hundreds ofspecies with immense biodiversity. Thanks to the National Institutes of Healths HumanMicrobiome Program researchers have been discovering the states of the human microbiomein health and disease. To put a more personal face on the patient of the future, I have beencollecting massive amounts of data from my own body over the last five years, which revealsdetailed examples of the episodic evolution of this coupled immune-microbial system. Anelaborate software pipeline, running on high performance computers, reveals the details of themicrobial ecology and its genetic components. As a result of discovering the "missing" 90% ofour bodies, we can look forward to revolutionary changes in medical practice over the nextdecade. 3. A Decade of eResearchPartnering With AustraliaBernard Pailthorpe, UQUniversity of MelbourneJulPhil Scanlan, AALDDavid Abramson, Monash UniversityChris Hancock, aarnet 4. From One to a Billion Data Points Defining Me:The Exponential Rise in Body Data in Just One DecadeBillion: My Full DNA,MRI/CT ImagesMillion: My DNA SNPs,Zeo, FitBitOne: Hundred: My Blood VariablesWeigMhyt WeightBloodVariablesSNPsMicrobial GenomeImproving BodyDiscovering Disease 5. Visualizing Time Series of150 LS Blood and Stool Variables, Each Over 5-10 YearsCalit2 64 megapixel VROOM 6. Only One of My Blood MeasurementsWas Far Out of Range--Indicating Chronic InflammationEpisodic Peaks in InflammationFollowed by Spontaneous DropsNormal Range