Construint una xarxa interdisciplinar de treball i coneixement

Harvard-MIT Biomedical Engineering Center

The Center,

What is

unique

about it?

“Construint una xarxa interdisciplinar de

treball i coneixement”Mercè Balcells-Camps, PhD

177 Massachusetts Avenue E25-438 | Cambridge MA 02139 USA

about it?- Education

- Research

- Industry

- International

Mercè Balcells-Camps, PhDMIT Research Scientist

Harvard-MIT Division of Health Sciences and Technology

[email protected]


The Center,

What is

unique

about it?

AGENDA

– Introduce the Harvard-MIT Biomedical Engineering Center (BMEC)

∗Education, research, innovation, industry, international

– Share an opportunity to become affiliated with BMEC through

2

about it?- Education

- Research

- Industry

- International

– Share an opportunity to become affiliated with BMEC through

IAccess program

∗international talent exchange

∗targeted seminars, hands-on trainings and expert advice



The Center,

What is

unique about

it?• Advance human health through academic excellence

in education and research that integrates science,

3

it?EDUCATION

RESEARCH

INNOVATION

INDUSTRY

INTERNATIONAL

in education and research that integrates science,

engineering and medicine.

• Educate outstanding minds, cultivate leaders, create

knowledge, and generate cost-effective preventative,

diagnostic, and therapeutic innovations.


US

Harvard


EDUCATION

MD, PhD Programs

Train students to carry their

engineering and scientific

expertise from the laboratory

bench to the patient's bedsideHarvard-MIT

4

US

Academiabench to the patient's bedside

and to bring clinical insights from

the patient's bedside to the

laboratory bench.

40MD, 15PhD, 5MD/PhD, 5MBA

US

HospitalsMIT

Harvard-MIT

BMEC

“teaches you how medical doctors

think and how they talk”Kay Furman, HST PhD candidate


US

Harvard


RESEARCH

Investigators have special access

to both universities' world-class

resources and to Harvard Medical

School's teaching hospitals.

This partnership facilitates

collaborations across disciplines Harvard-MIT

5

US

Academiacollaborations across disciplines

and leverages the strengths of

multiple institutions.

As a result, our researchers

accomplish more than they could

independently:

US

HospitalsMIT

Harvard-MIT

BMEC


=>Top publications, awards, IP, $$$,…


ACHIEVEMENTS

Smart hardware

EKG, monitors

Intensive care unit medicine

Space Medicine

SoftwareUS

Harvard

Harvard-MIT


Software

Hospital and clinical

Integrated functional biology

Devices

Drugs

Gene Therapy

Tissue and cell engineering

US

Academia

US

HospitalsMIT

Harvard-MIT

BMEC

6

8

10

CE

LL N

UM

BE

R/1

051 x 4 x 0.3cm 3

Matrix

Allogeneic EC

Viability Assay

TISSUE ENGINEERED EC

7

In VivoIn Vivo

Paracrine regulation ofArterial Repair

147000

2

4

TIME (days)

CE

LL N

UM

BE

R/1

0

Vascugel ®

AcLDL Uptake

Vein

I

AV ACCESS

Vein Graft

Sponge

Sponge

Nugent, et al. Nugent, et al. J Vasc Res J Vasc Res (2002)(2002)

Artery MEEC 56 dVein

II

ArteryVeinControl 56 d

I

I

II

I

LumenLumen

Vein

ArterySponge

Sponge

$700 million$700 million

research/yearresearch/year Deshpande


“MIT INNOVATION ECOSYSTEM”

I-Teams

VCPE

MIT SloanSEBC

Enterpreneurship

Center

100K

competition

Enterprise

Forum

9

research/yearresearch/year Deshpande

Center


Academic

Research

Commercial

EnterpriseCOMMERCIALIZATION

MIT TLO

Center

MIT VMS


Deshpande Center (2002)

• Gift of $17.5MM from Desh and Jaishree Deshpande

• Have raised additional $4MM since from donors, corporations

• Grants: - 500 proposals


• Results:

- 500 proposals

- 72 projects

- $11+MM grants

- 200+ faculty/students

- 100+ volunteers (catalyst program)

- 22 start-ups + 1 license

- Capital >$180 MM


� Active Spectrum Test Equipment

� Beam Power Amplifiers for Wireless

� Brontes(3M) Dental Imaging

� ERC Titanium production

� Entra Drug delivery

� Hepregen Drug Discovery

� Molecular Stamping Nano Production

Spinouts


� Molecular Stamping Nano Production

� Myomo Stroke Rehabilitation

� Pervasis Tissue Repair

� Pufco Secure Processors

� QD vision Displays

� Sentina Auto Sensors

� Taris Biomedical Drug Delivery

� 1366 Solar Cells

� Vertica Database Software

Harvard


Regulatory

Agency

FDA

Harvard-MIT

BMEC

Preclinical

CBSET

ACHIEVEMENTS

Smart hardware

EKG, monitors

Intensive care unit medicine

Space Medicine

Software

International?International?

12

MITUS

Industry

US

Hospitals

BMEC


Software

Hospital and clinical

Integrated functional biology

Devices

Drugs

Gene Therapy

Tissue and cell engineering

International? International?



MITMIT--SPAINSPAIN


MIT-Spain en números

3.5 Anys d’operació

1 de 5 Estudiants de MIT que busquen oportunitats a l’estranger escull MIT-Spain

170 Incorporacions de talent de MIT en empreses, centres i universitats arreu l’Estat; 321 solicituds

40% A Catalunya


40% A Catalunya

95% Index de satisfacció entre hosts i estudiants

18 Visites de professors del MIT (seminaris, congressos, assessoria, ...)

11 Actes organitzats a Barcelona o al MIT

54 Projectes punters de col.laboració descuberts; 14 finançatsMIT-Spain/La Cambra Seed Fund for collaborative research


Preclinical

CBSET

Regulatory

Agency

FDA, EMAHarvard-MIT

BMEC

A GLOBAL OPPORTUNITY: International Access Program (IACCESS)

Biocluster de BCN

a cutting edge model based

on the successful academia-

industry relationship at BMEC


Hospitals

World wide

International

Industry

BMEC Biocluster de BCN

Sant Pau

Biopol’H

H. Clínic

Vall d’Hebron

Parc UB

Parc UAB

IQS…

Grifols

Almirall

Ferrer

Esteve

CH Werfen

IHT

Lipotec…

La Cambra de Barcelona


ACTIVITIES

PARTNER

Sponsored

Research

Project

IAccess

Seminars

IAccess

Visitor

Program

Founding

Patron

EducationCollaborative Research


Industrial

Collaborator

Educational

Partner

Included Optional


IAccess Visitor Program: IAccess Visitor Program:

Structured rotation that enables

engineers learn medicine and vive versa

Harvard-MIT

Biomedical Engineering

Center

Mass General Hospital

St. Elizabeth’s Medical

Center

Brigham and Women’s Hospital


IACCESS

Member InstitutionConcord Biomedical Sciences

and Emerging Technologies


* The Harvard-MIT Biomedical Engineering Center as an example of

how at MIT we:

- integrate science, engineering and medicine

- educate outstanding minds, and cultivate leaders

- leverage the strengths of multiple institutions

* IAccess is a cutting edge model based on the successful academia-

industry relationship at BMEC:


industry relationship at BMEC:

- international talent exchange

- targeted seminars, hands-on trainings and expert advice

* Initial (seed) grant from La Cambra to move operation concept

forward in Barcelona

* Opportunity for a second founding patron in the short term


Acknowledgements


La Cambra de Comerç de Barcelona

Institut Químic de Sarrià


Health & Medicine

Construint una xarxa interdisciplinar de treball i coneixement