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brief introduction for antibiotic resistance & START group of IFMSA.
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ANTIBIOTIC RESISTANCE
Aveen Omer
Hawler College of Medicine/Kurdistan
The word antibiotic comes from the Greek anti meaning 'against' and bios meaning 'life‘
' Antibiotics are also known as antibacterials.
What are antibiotics?
Drugs used to treat infections caused
by bacteria. An antibacterial is a compound or
substance that kills or slows down the growth of bacteria
Many mechanism: 1. inhibiting cell wall growth and
synthesis. 2.Alter ribosomal function by
inhibiting protein synthesis. 3. Interfere with replication of
DNA or RNA.
How Antibiotics work?
4. Drugs block the metabolic
pathway essential for the life of the micro-organism.
5. Disruption of the cell membrane permeability.
Occurs when an antibiotic has lost
its ability to effectively control or kill bacterial growth.
The bacteria are "resistant" and continue to multiply in the presence of therapeutic levels of an antibiotic.
What’s antibiotic resistance?
Mechanisms:1. Production of drug-inactivation
enzymes.2. Structural modification of
antibiotic target site.3. Anaerobic bacteria are resistant
to the actions of Aminoglycosides
How bacteria get resistance to Antibiotics??
4.Altered uptake of
antibiotics>> resulting in decreased permeability, increased efflux.
5. Development of alternative metabolic pathways.
Why is antimicrobial resistance a global concern?
1. Antibiotic resistance kills.
2. Antibiotic resistance impedes the control of infectious agents.
3. with the problem of Antibiotic resistance progressing.. Threats increase to return to the pre-antibiotic era!
4. Resistance of infectious agents to antibiotics, increases the costs of health care.
5. Jeopardizes health-care gains to society.
6. Threatens health security, and damages trade and economies.
1. Doctors who have become slave of habit.2. prescribing>> without checking for the antibiotic sensitivity tests and also using broad spectrum antibiotics.3. Cultural conceptions and patients demands.4.Antibiotics are on the-counter drugs.
Causes of Antibiotic resistance spreading;
5. poverty6. Patient compliance7.The enormous growth of global trade and travel •“Trade and travel have increased the speed and facility with which both infectious diseases and resistant microorganisms can spread between continents.”
8.Antibiotic use in food production and animal care
In several parts of the world, more than 50% in tonnage of all antimicrobial production is used in food-producing animals.
Would you like to be a
doctor in a world where there were no antibiotics???
Changing word to actions
For 1 moment…STOP…
and..THINK…
What’s being done
globally???
•An international initiative with its base in Sweden
•Goal to reduce the development on antibiotic resistance
• www.reactgroup.org
React- Action on Antibiotic Resistance
Student’s Targeting Antibiotic
Resistance Today!
PUTITNG A SOTP TO ANTIBIOTIC RESISTANCE!
START
PUTITNG A SOTP TO ANTIBIOTIC RESISTANCE!
An IFMSA group. Established>> December 2011 Cecilia Kållberg >>>Sweden Jannie Dressler >>>Denmark About 50 members, from 29
different countries!
Webpage group Presentation/campaign group Article group Connections to stakeholders Policy Statement group
START structure
1. To educate and raise awareness. To create awareness about the
topic/ to educate people on the hazards of indiscriminate use of antibiotics.
To prevent the consicuances.
Short-term goals:
2. To create material To create material that could be
used by students when educating others
To produce material that could be used beside presentations (posters etc.)
To share standard treatment
guidelines amongst students at our universities
To conduct a survey on physicians knowledge about antibiotics and antibiotic resistance (se point 3 on the agenda)
1.To engage other groups.a. To ask med faculties to add
classes on the subjectb. To ask hospitals to educate their employees also
Long-term goals:
1.START>> gathering a group of interested students and members of IFMSA… also doctors
2.Activities>>Seminars, Workshops…etc.
3.Data collecting…surveys
How to start locally…
Thanx