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Acupuncture and Manual Therapy:Parallels in Research and Clinical Practice
Mark SextonMISCP
The Physios
Enriching our wellbeing
Physiotherapists get people moving
The Plan
Nothing is,All is becoming
Lao Tzu
Helene LangevinThomas MyersMax ZusmanLorimer Moseley
Helene LangevinThomas MyersMax ZusmanLorimer Moseley
Mechanotransduction
So What!
Clinical RelevanceResearch RelevanceEducation relevance
Acupuncture - Key Principle Remote/Systemic
LocalAdjacent
Needle Grasp/De Qi
Body-Wide Integrative System
Every Cell, Organ, System
HomeostasisLocal RepairRemote Effects
The MeridialSystem
Meridial System and Connective Tissue
Connective TissueSystem
Langevin 2001
Langevin 2001
Connective Tissue Whorl
Langevin 2001
Connective Tissue Whorl
Langevin 2002
Mechanical Coupling
Langevin 2001
Langevin and Yandow 2002
Relationship of Acupuncture Points and Connective Tissue planes
80% Points Correlate CT Plane
Points – Greater Access to CT
50% Meridian Intersections - CT Planes
Fibroblast Response to Needling
Langevin 2004, 2006, 2010, 2011a,b,c
Fibroblast Cell Cytoskeleton
Cytoskeletal Tensegrity
Fibroblast Cell Cytoskeleton
Mechanotransduction2-D Representation : Fibroblast in ECM
Integrins
Swartzlander 2011 (ZurichMinds)
TGFb-1
Mechanotransduction
Integrins
Swartzlander 2011 (ZurichMinds)
Tendon tissue provides an example of cell–cell communication.
Khan K M , Scott A Br J Sports Med 2009;43:247-252
©2009 by BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine
Tendon tissue provides an example of cell–cell communication.
Khan K M , Scott A Br J Sports Med 2009;43:247-252
©2009 by BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine
Tendon tissue provides an example of cell–cell communication.
Khan K M , Scott A Br J Sports Med 2009;43:247-252
©2009 by BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine
Mechanical loading stimulates protein synthesis at the cellular level.
Khan K M , Scott A Br J Sports Med 2009;43:247-252
©2009 by BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine
Mechanical loading stimulates protein synthesis at the cellular level.
Khan K M , Scott A Br J Sports Med 2009;43:247-252
©2009 by BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine
Mechanical loading stimulates protein synthesis at the cellular level.
Khan K M , Scott A Br J Sports Med 2009;43:247-252
©2009 by BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine
Fibroblast Remodelling
Langevin 2006
Fibroblast Remodelling Langevin 2006
Fibroblast Network
Less Dense Connective Tissue
No Gap Junctions
Connexin 43 present
Langevin 2010
Fibroblast remodelling
Nuclear processes – mRNAChemical Cascades
Fibroblast Cell – ECM Traffic
Fibroblast Remodelling
Nuclear processes – mRNAChemical Cascades
Fibroblast Cell – ECM Traffic
Collagen SynthesisTissue Repair
All Movement has Effect…
…and Vice-Versa
Langevin 2001
Langevin HM and Sherman KJ,
Pathophysiological Model for cLBPIntegrating
Connective Tissueand
Nervous System Mechanisms
Med. Hyp. 2006
Connective Tissue
Plasticity
Pathogenic Mechanism
Langevin 2006
Neural Tissue
Plasticity
Connective Tissue
Plasticity
Pathogenic Mechanism
Langevin 2006
Connective Tissue
Plasticity
Pathogenic Mechanism
Langevin 2006
Pathogenic Mechanism
Langevin 2006
Pathogenic Mechanism
Langevin 2006
Pathogenic Mechanism
Langevin 2006
Pathogenic Mechanism
Langevin 2006
MovementPostureExercise
Treatment
Tissue Pathology
Dysfunction
Direct Tissue Mechanical Stimulus
Cognitive/BehaviouralMovementTreatment
Placebo
PsychosocialGenetic
Pathogenic Mechanism – Therapeutic interventions
Langevin 2006
The Home Straight !!
Helene LangevinThomas MyersMax ZusmanLorimer Moseley
Mechanotransduction
So What!
Clinical RelevanceResearch RelevanceEducation relevance
Mechanotransduction….
Connective TissueSystem
Physiotherapists get people moving
The Physios
Enriching our wellbeing
Acupuncture and Manual Therapy:Parallels in Research and Clinical Practice
Mark SextonMISCP
Thank You!Aisling SextonMary PenderValerie ReillyRowan ManahanJudy MurphyBrona FullanErica McMullanDamian Rice
