SICKLE CELL ANEMIA

FULLANTE, Kasey Anne E.

DMD 2D

A. DefinitionA genetic blood disorder caused by the presence of an abnormal form of hemoglobin. These hemoglobin molecules tend to aggregate after unloading oxygen forming long, rod-like strictures that force the red cells to assume a sickle shape.

Signs & Symptoms

Fatigue (tiredness) pale skin nail beds Jaundice shortness of breath Sudden episode of pain throughout

the body.

Oral Manifestation

An increased risk for periodontitis, or gum disease

Abnormally pale tissue in mouth Glossitis

GLOSSITIS

PALE GUMS

PERIODONTITIS

Oral Care

SCD patients must undergo a thorough oral and dental examination, using appropriate radiographs.

Proper hygiene. Strict dental appointments. Extractions should be done

atraumatically

Classification of Sickle Cell Anemia as a disease:

•Mendelian- autosomal recessive genetic disease

•Cytogenetics- The HBB gene is found in region 15.5 on the short (p) arm of human chromosome 11.