Importance of Clinical Research Networks

On Behalf of HRB-Clinical Research Facility Galway

NUI Galway/WNWHG

In my Healthcare setting, clinical research is

• A nuisance

• A luxury

• Important, but funds should be used elsewhere

• An essential part of healthcare

Higgins Report

The report emphasises the importance of academic linkages to focus on the research, innovation, education and training agendas that are so fundamental to improved patient care

Overview

• Importance of a Clinical Research Network

– Health Care Group/Network

• Advantages of Clinical Research Network

• Developments in WNWHG and NUI Galway

Clinical Research Network

• New Therapies

• Diagnostic tests

• Clinical Pathways

• Cost-effectiveness

• Determinants of healthcare outcomes

• Health Services

• Community/GP

• National/International

Participation in Clinical Research (Quality of Care and Outcomes)

494 Hospitals (n=174,062 with ACS)

Use of Evidence-based Therapies In-hospital Mortality

Majumdar et al JAMA-Int Med 2008

CRUSADE Registry

Clinical Research Network

Clinical Research Network(National, Regional, Local)

• Data Management• Pharmacovigilance• Trial Coordination• Biostatistics/Biometrics

• Recruitment• Coordination• QRA

HRB

Clinical Research Network(Health Care Group)

Access to research studies

Clinical Research Network(Informing Service Development)

• Data Management• Biostatistics/Biometrics

• Health Service• Value-based Health Care

• Community/GP• Collaborations

Clinical Research Team, HRB-CRFG

Since 2008, our staff complement has grown from 5 to 43 members.

Our 43-person staff includes;

Director, Associate Director, Programme Manager, Clinical Research IT Manager, Research Nurse Manager, Quality and Regulatory Affairs Manager, Biostatisticians (3), Study Coordinator (1), Research Nurse (14), Research Assistants (5), Database Developer (1), Research Pharmacists (2), Administrative Assistant (1), Data Manager (3) and Data Associates (2).

PhD student candidates, each of whom holds personnel awards.

Training

• MSc Clinical Research

– 38 active students

• 4th Annual Biostatistics Summer School delivered June 2013

• Workshops in Biostatistics

• GCP training

HRB CRFG Current Research Activity

Cumulative Number of Studies at HRB-Clinical Research Facility (2008-2013)

Clinical Research Activity

HRB-Clinical Research Activity

• Funding• Publications

HRB-Clinical Research Facility-Galway

• 7 Consulting Rooms

• 8 Bed Outpatient Beds

• 8 Bed Inpatient Ward

• Minor Operations Room

• Endoscopy Suite

• Endocrine Suite

• Cardiorespiratory Suite

• Phlebotomy Room

• Biometrics Unit

2007: Capital funding for the HRB ClinicalProjected commencement date is Sept 2013Completion projected Jan 2015Health Research Board

HRB-Clinical Research Facility-Galway

• 7 Consulting Rooms

• 8 Bed Outpatient Beds

• 8 Bed Inpatient Ward

• Minor Operations Room

• Endoscopy Suite

• Endocrine Suite

• Cardiorespiratory Suite

• Phlebotomy Room

• Biometrics Unit

2007: Capital funding for the HRB ClinicalProjected commencement date is Sept 2013Completion projected Jan 2015Health Research Board

Clinical Research Network(Health Care Group)

Access to research studies

Challenges

• Culture of Clinical Research in Clinical Medicine

– Engaging people in clinical research

• Sustainable Funding Model

• Retention of Specialist Staff (Career-track)

• Increase Quality of Research Outputs

Opportunities

• Integrated clinical and academic research community

• Data-informed development in clinical service

• Deliver opportunity of research studies to patients

• Contribute to advancing useful medical knowledge