Mark Sykes, Fera Science Limited

Enhancing Halal Sustainability through

Halal Research and Innovation

The largest and

longest serving

provider of agri-food

research, services and

regulatory advice in

the UK

The trusted provider

to governments and

the commercial sector

Meet the numbers, face the challenge

The world population will increase

by 2.4 billion by 2050 to 9.4 billion

This population is expected to be

wealthier, eating more and

differently

It is estimated that we will need to

produce between 60-110% more food

It is estimated that 40% of global

production is lost to pests and

diseases

Working hard to meet the challenges of food supply in the 21st Century

Delivered in partnership with government,

industry and society, globally

Fera bridges the interests of

governments, the commercial

sector and the public

− Operating at the leading edge of

current and future needs

− Progressing evidence-based consensus

on issues of concern and sensitivity

Fera International & the fields within which we work

Crop protection & economic yield

potential

− Plant health diagnostics and pesticide

resistance

− Farmer practice / agri-dealer inputs database

Food safety and quality, including

authenticity and fraud

− Pesticides, toxins and isotopes

− Food trade risk database products

Land-use, farming stewardship and eco-

sustainability

− Land use, design and ecosystem services

− Eco-toxicity and fate of agri-chemicals

Crop protection and economic yield potential

Supporting pest prevention at

import borders and in fields

− Plant health capacity in pest risk

analysis, inspection and

diagnostics

− Monitoring field pest and diseases,

including mycotoxins

− Tracking emergence of new pests,

evolving virulence and pesticide

resistance

− Data bases for risk analysis

decision-making

− Training

Providing assurance along the

food supply chain

− Food safety testing for

contaminants, pesticide residues

and microbials

− Food authenticity and detection

of fraud

− Knowledge products for

regulatory compliance

− Proficiency testing schemes for

analytical competence (Fapas®)

− Emerging risks to food supply and

procurement

− Training

Food quality, safety and authenticity

Contract Laboratory

Cost-efficient, timely delivery,

customer focussed

National Institute – National Reference Laboratory

Representation at national and international level

R&D Institute

Applied R&D underpinning policy,

supporting NPD, delivering solutions

Food Quality, Safety and

Authenticity

Fapas® Proficiency Testing

Laboratory assurance

meeting the highest

standards

Food Chemistry

Food Microbiology

GM Materials

Water and Environmental

Bespoke: tests to your

specifications

Reference Materials

Fapas®

Operates via agencies in 43 countries

Participation greatly assists ISO17025

accreditation

Case study - Wood and source of origin

for ethical and sustainable production

(EU) 995/2010) stipulates that importers of tropical timber must be able to

identify the origin of timber used in their products

Since March 2013, it has been a criminal offence to sell endangered species

of timber in the European Union without a FLEGT licence

Analysis of the light bio-elements of carbon, hydrogen, oxygen, and sulphur

offer the potential to reveal the country/ region of origin of timbers

Chemical profiling and genetic analyses offer additional levels of

confirmation

Stewardship for Sustainable, Safe and

Ethical Crop Production Overseas/UK

The Fera 3SECP approach to bench marking sustainability

Sustainable, safe and ethical sourcing of food is increasingly critical to

brand value and rigorously assessed for scientific merit.

Fera is uniquely able to evidence the scientific outcomes that support the

needs of crop production chain stakeholders and a 3SECP standard.

Production Economy

Carbon Economy

Nutritional Economy

Ecosystem services Economy

Water Economy

Societal Economy

PT 19194, pesticide residues in tomato

112 registered participants from 32 countries

BRAZIL MOROCCO

CANARY ISLANDS NETHERLANDS

CHILE PANAMA

CHINA POLAND

COLOMBIA SINGAPORE

CYPRUS SOUTH AFRICA

EGYPT SPAIN

FRANCE SWITZERLAND

GERMANY TAIWAN

GREECE THAILAND

HONG KONG TURKEY

ITALY UGANDA

JORDAN UNITED ARAB EMIRATES

SOUTH KOREA UNITED KINGDOM

MALAYSIA USA

MEXICO VIETNAM

69

92

43

100

99

58

42

102

2 21

103

106

24

56

64

80

94

57

9 82

37

93

29

14

18

65

79

22

26

83

27

87

61

85

46

40

98

95

1 34

86

107

48

4 77

68

88

55

49

5 3 7 28

51

91

90

59

12

39

54

62

89

47

52

60

8 73

75

13

19

38

35

36

6 41

33

44.2 µg/kg

30.7 µg/kg

17.2 µg/kg

-5.0

-4.0

-3.0

-2.0

-1.0

0.0

1.0

2.0

3.0

4.0

5.0

6.0

7.0

8.0

z-s

co

re

Laboratory Number

Pyriproxifen z-score chart

Laboratory assurance

meeting the highest

standards

Food chemistry

Food microbiology

GM Materials

Water and environmental

Bespoke: Tests to your

specifications

Reference Materials

ISO 17043 accredited

Agents in 43 countries

Case study – Quality assurance and

Fapas® Proficiency Testing

0009

Economics of Food Sustainability

Melamine

Illegal vet drugs

Recycling oil

Halal Sustainability

What is scientifically possible to

determine?

What can Fera as learn from

this?

What projects can we initiate as

a result?

Scientific possibilities ?

Authenticity Proficiency Testing

Results of an authenticity PT

Analyte Assignment No. results

satisfactory

Total number

of results

%

satisfactory

beef present 41 41 100

chicken absent 39 41 95

pork present 42 44 95

Results of FAPAS PT 2959, lamb

Should we be concerned?

What was the contamination level?

What methods were being used?

Methods trends, DNA, non-DNA

2009

ELISA

PCR

2014

ELISA

PCR

2009

PCR accredited

PCR not accredited

2014

PCR accredited

PCR not accredited

Previous work at Fera

2007, bovine

2008, porcine

Proteomics and Gelatine

• Byproduct from the meat / fish industry

• High temperatures, acid/alkali treat in industry

• Collagen

Current research at Fera

Industrial production

Uses of Gelatine

Protein analysis

A = Alanine M=Methionine

C = Cysteine N=Asparagine

D= Aspartic acid P=Proline

E=glutamic acid Q=glutamine

F= Phenylalanine R =Arginine

G=glycine S=Serine

H=Histidine T=Threonine

I=Isoleucine V= Valine

K = Lysine W = Tryptophan

L=Leucine Y=Tyrosine

-CCTAUGGGUGAUGAAUUUAAACGAAAUUUAGCUAUUACUGUUUCUCCUCAACAUUAUUGU

Protein sequence

database

www.uniprot.org

Mass Spectrometry

Fragment ion spectrum of cow collagen peptide :

GETGPAGPAGPIGPVGAR (precursor mass 1560.8064)

Fragment ion spectrum of complementary pig sequence :

GETGPAGPAGPVGPVGAR (precursor mass 1546.7915)

On-going development

Determine the species origin of gelatine in foods

• Mass spectrometry method

• Screen for species-specific peptides from a proprietary database

• Matrices: gelatine, desserts, confectionery, processed meats,

capsules, injection mixes and meat exudate…

• Reporting limit – matrix specific, aim for 0.4-1.0%

What do we do next?

• Continue food monitoring programmes

• Increase accreditation and certification

• Understand laboratory capability

• Expand associated quality assurance

• Develop appropriate proficiency tests

• Develop appropriate reference materials

• Collaborate with the official bodies

Fera

Enhancing Halal Sustainability through Halal

Research and Development

Acknowledgements

YB Dato’ Haji Abdul Malik Kassim

PIHH Secretariat

Joseph Chan, TMS Malaysia

Fera Colleagues

Helen Grundy

Andrew Swift

Kate Somerwill

© Copyright Fera Science Limited