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Hemodynamic Disorders
Edema Hyperemia and Congestion HemorrhageHemostasis and ThrombosisEmbolismInfarction Shock
1
Dr. Krishna Tadepalli, MD, www.mletips.com
Infarction Definition = ischemic necrosis of tissue due to occlusion
of arterial ( in most of cases) or venous ( in gonads) circulation
Most common cause of Death in USA Most commonly in 99% of cases = arterial occlusion
by thrombo-embolism Rarely venous drainage problem ( in Testis, Ovary) Very rarely vasospasm
Morphological Types Red & White Wedge shaped with base at the periphery of organ
Final outcome Coagulative necrosis ( Liquefactive in Brain)
Septic infarction = in pts. With infective Endocarditis
Infarction Definition = ischemic necrosis of tissue due to occlusion
of arterial ( in most of cases) or venous ( in gonads) circulation
Most common cause of Death in USA Most commonly in 99% of cases = arterial occlusion
by thrombo-embolism Rarely venous drainage problem ( in Testis, Ovary) Very rarely vasospasm
Morphological Types Red & White Wedge shaped with base at the periphery of organ
Final outcome Coagulative necrosis ( Liquefactive in Brain)
Septic infarction = in pts. With infective Endocarditis2
Dr. Krishna Tadepalli, MD, www.mletips.com
Infarctions- Types
Red (Hemorrhagic) Venous occlusion In loose tissues
(lung) Organs with dual
blood supply (Lungs, Liver)
Previously congested organs ( nutmeg liver)
Re- perfused tissues
Red (Hemorrhagic) Venous occlusion In loose tissues
(lung) Organs with dual
blood supply (Lungs, Liver)
Previously congested organs ( nutmeg liver)
Re- perfused tissues
White (Anemic)• Arterial occlusion• Solid organs• End arterial supply
( Kidney, Spleen, Retina, Heart)
White (Anemic)• Arterial occlusion• Solid organs• End arterial supply
( Kidney, Spleen, Retina, Heart)
3
Dr. Krishna Tadepalli, MD, www.mletips.com
Infarction
Red & White
4
Dr. Krishna Tadepalli, MD, www.mletips.com
Final outcome of Infarction in heart Final outcome of Infarction in heart
How old is it ( after the onset of MI)?5
Dr. Krishna Tadepalli, MD, www.mletips.com
Final outcome of Infarction in heart Final outcome of Infarction in heart
How old is it ( after the onset of MI)?5
Dr. Krishna Tadepalli, MD, www.mletips.com