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7. infarction; hemodynamic disorders

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Page 1: 7. infarction; hemodynamic disorders

Hemodynamic Disorders

Edema Hyperemia and Congestion HemorrhageHemostasis and ThrombosisEmbolismInfarction Shock

1

Dr. Krishna Tadepalli, MD, www.mletips.com

Page 2: 7. infarction; hemodynamic disorders

Infarction Definition = ischemic necrosis of tissue due to occlusion

of arterial ( in most of cases) or venous ( in gonads) circulation

Most common cause of Death in USA Most commonly in 99% of cases = arterial occlusion

by thrombo-embolism Rarely venous drainage problem ( in Testis, Ovary) Very rarely vasospasm

Morphological Types Red & White Wedge shaped with base at the periphery of organ

Final outcome Coagulative necrosis ( Liquefactive in Brain)

Septic infarction = in pts. With infective Endocarditis

Infarction Definition = ischemic necrosis of tissue due to occlusion

of arterial ( in most of cases) or venous ( in gonads) circulation

Most common cause of Death in USA Most commonly in 99% of cases = arterial occlusion

by thrombo-embolism Rarely venous drainage problem ( in Testis, Ovary) Very rarely vasospasm

Morphological Types Red & White Wedge shaped with base at the periphery of organ

Final outcome Coagulative necrosis ( Liquefactive in Brain)

Septic infarction = in pts. With infective Endocarditis2

Dr. Krishna Tadepalli, MD, www.mletips.com

Page 3: 7. infarction; hemodynamic disorders

Infarctions- Types

Red (Hemorrhagic) Venous occlusion In loose tissues

(lung) Organs with dual

blood supply (Lungs, Liver)

Previously congested organs ( nutmeg liver)

Re- perfused tissues

Red (Hemorrhagic) Venous occlusion In loose tissues

(lung) Organs with dual

blood supply (Lungs, Liver)

Previously congested organs ( nutmeg liver)

Re- perfused tissues

White (Anemic)• Arterial occlusion• Solid organs• End arterial supply

( Kidney, Spleen, Retina, Heart)

White (Anemic)• Arterial occlusion• Solid organs• End arterial supply

( Kidney, Spleen, Retina, Heart)

3

Dr. Krishna Tadepalli, MD, www.mletips.com

Page 4: 7. infarction; hemodynamic disorders

Infarction

Red & White

4

Dr. Krishna Tadepalli, MD, www.mletips.com

Page 5: 7. infarction; hemodynamic disorders

Final outcome of Infarction in heart Final outcome of Infarction in heart

How old is it ( after the onset of MI)?5

Dr. Krishna Tadepalli, MD, www.mletips.com

Page 6: 7. infarction; hemodynamic disorders

Final outcome of Infarction in heart Final outcome of Infarction in heart

How old is it ( after the onset of MI)?5

Dr. Krishna Tadepalli, MD, www.mletips.com