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PRESENT BY
ROZANA ABOALKHAIR
GLUCOSE NANOSENSOR TATTOO
OVERVIEW
• INTRODUCTION
• GLUCOSE NANOSENSOR TOOLS
i- INJECTOR
ii-NANOSENSOR TATTO
iii- IMAGING DEVICE
• CONCLUSION
Diabetes Has Become Epidemic • Every day,
3,600 new cases of diabetes are diagnosed.
580 people die of diabetes-related complications.
225 people have a diabetes-related amputation.
120 people with diabetes progress to end-stage renal disease.
55 people with diabetes become blind.
American diabetes association, May,2012.
GLUCOSE NANOSENSOR TOOLS
• Injector
• Nanosensor tattoo
• Imaging device
Trends in Molecular Medicine, Volume 16, Issue 12, 584-593, 23 September 2010
PLACEMENT IN SKIN
Skin Pharmacol Physiol,2009
PLACEMENT IN SKIN
Skin Pharmacol Physiol,2009
Nanosensors composed of a hydrophobic polymer containing:
• Lipophilic glucose recognition elements
(boronic acid derivatives, PhB(OH)2 )
• Fluorescent reporters. (alizarin, C14H8O4 )
Trends in Molecular Medicine, Volume 16, Issue 12, 584-593, 23 September 2010
NANOSENSOR TATTOO COMPONENTS
Imaging Device
Trends in Molecular Medicine, Volume 16, Issue 12, 584-593, 23 September 2010
CONCLUSION• minimize the need for the implantation of electrochemical sensors , which minimizes
patient inconvenience and pain.
• Can performed when the patient is sleeping.
• Provide a means to measure the glucose levels continuously instead of only specific time.
• It would be an additional cost of producing this smart tattoo, by thoroughly comparing the smart tattoo with other commercially available nanosensors.
• The tattoo, like most cutting-edge technologies have drawbacks, but can be turned around to full efficiency.
Reference • American Diabetes Association. (2012). "Diabetes Basics.”
• Cash, Kevin J., and Heather A. Clark. "Nanosensors and nanomaterials for monitoring glucose in diabetes." Trends in molecular medicine 16.12 (2010): 584-593.
• Card, Jeffrey W., and Bernadene A. Magnuson. "A review of the efficacy and safety of nanoparticle-based oral insulin delivery systems." American Journal of Physiology-Gastrointestinal and Liver Physiology 301.6 (2011): G956-G967.
THANK YOU…