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INFORMACIÓN CONFIDENCIAL· Uso exclusivo interno· Prohibida su reproducción · Derechos de imagen protegidos
Water is life
Every day our body looses liquids and mineral salts needed for correctly carrying out vital functions.
When any physical activity is started, the body temperature increases and water is essential for regulating it.
When we take care over what we eat, we sometimes forget that it is also important to keep ourselves hydrated.
We must drink about two litres of water every day
Hydration is very important because it improves the body’s performance and prevents injuries.
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Water and cells
The amount of water we must drink depends on: physical exercise, climate conditions, body mass, etc.
Our body has ways of obtaining water from where apparently it is not possible, from our cells.
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BalanceNet movement
of water towards
the outside of the
cell
Net movement of water
towards the inside of the cell
The defect: Dehydration
When we do not have enough water in the body we suffer from dehydration:
1 We feel particularly listless and tired.2 We loose muscular tone and firmness, which accelerates the premature ageing process.3 It reduces the skin’s natural protection, epicutaneous emulsion.
Main problems associated with the skin
Lack of radiance, Dull, ListlessAppearance of wrinkles
Loss of muscular and cutaneous tonePigmentation disorders, etc.
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Skin alterations
Skin tightness
Greyish, opaque appearance (lack of radiance)
Sensitivity to irritation and itchiness
Appearance of lines or grooves
Pigmentations
Cutaneous asphyxiation and spots
Scaling
Loss of water
pH imbalance
EPIDERMIS
CORNEOUS LAYER
Loss of density
Reduction of the skin’s defences
Lack of oxygenation
DERMIS
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HYDRATION - TOP CLAIM
oHydration is one of the top claims in leading cosmetic markets, even in prestigious products.
Source: Mintel GNDP, 2010
The molecular cosmetic platform
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POWER: The molecular cosmetic platform
We have created a molecular cosmetic platform called POWER. This platform has started with the launch of POWER C+.
The aim is to provide a wide range of products based on the power of an active ingredient.
There are extensive advantages, as communication is much simpler because we have the marketing already created . This means it is possible to reach a wide range of consumers.
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The line
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POWER HYALURONIC
Power Hyaluronic, the natural skin hydrodynamics treatment which combineshyaluronic acid of different molecular weights with an aquaporins actuator,the proteins in charge of transporting the water to the heart of the cell.
Aim: to balance the skin’s natural hydrodynamics and obtain an optimum degreeof hydration.
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Skin hydrodynamics
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POWER HYALURONIC: Skin hydrodynamics
Hydrodynamics is the measurement of water supply (inlet) and loss (outlet) flows in the skin.
If they are balanced, the skin maintains is optimum degree of hydration, which guarantees the renovation process and standardises the cutaneous microrelief.
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Active ingredients
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Active ingredientsHyaluronic Acid (HA)
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Affinity with water
•Hydrophyllic molecule
•Negative charge with sodium salts
• Can increase its size 1000 times between 5 and 12 hours.
3. Granger et al., 1984 - Ogston et al., 1961b
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Where is it formed in our body?
• It is found naturally in the human body.
• 15g of HA in 70kg of the human body.
Sinovial liquid (articulations) = 3500 mg/kg
Cartilage (around the cells) = 1200 mg/kg
Skin =300-900 mg/kg
Eye=200 mg/kgHyaluronic acid
HA is a lubricant capable of retaining 15 Kg of water in the body
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Functions of native HA in the skin
1) Hydration in the different tissues (skin, eyes, places of
mucous secretion, etc.).
2) Maintains the viscoelasticity of the sinovial fluid in
articulations, and helps to prevent inflammation.
3) Improves cell multiplication by contributing to the
mobility of the transport of nutrients.
4) Water retention by the NMF molecules in the
epidermis.
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Corneocytes
Langerhans cell
KeratinocyteMelanocyte
Collagen
Elastine
HA
Fibroblast
Macrophage
Adipocyte
Frazer J RE, Laurent TC, Laurent UBG. Hyaluronan: its nature, distribution, functions and turn over. J Intern Med 1997;242:27-33.
Origin of HA. BIOTECHNOLOGICAL PROCESS
The HA in Power Hyaluronic is obtained from BIOSYNTHESIS.
It is extracted from microorganisms of living cells (streptoccocus).
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WHEAT
Gluten Starch
Peptides Glucose
Specific developed
lactic bacteria
Bioethanol
WHEAT SUGARBEET
FERMENTATION PURIFICATION PRECIPITATION
HYALURONIC ACID
LOW
AVERAGE
VERY HIGH
VERY LOW
Skin penetration depends on the molecular weight of the HA.
>500 kDa
100-500 kDa
20-100 kDa
<20 kDa
Penetration of the HA fragments
*Dosis for cutaneous activity: 0.01 to 0.5%
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HA fragments Biological function on the skin
Type Biological function on the skin
Very HighY
High
Protective activity against environmental agents which cannot penetrate further than the stratum
corneum.
AverageTissue renewal and penetration as far as the middle
layer of the epidermis.
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Type Biological function on the skin
Low They are associated with the intracell links and skin cohesion.They penetrate as far as the deep layer of the epidermis.
VeryLow
They reach the dermis and stimulate the synthesis of new hyaluronic acid in fibroblasts, ensuring the skin’s main water
reserve, dermal reserve.
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HA fragments Biological function on the skin
ACTIVE INGREDIENTS Fragmented Hyaluronic acid
Power Hyaluronic has been formulated using fragments of very low and high molecularweight to hydrate the skin in depth and at the same time protect it from premature water losscaused by aggressive external agents.
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HA of very low
Molecular weight
HA of high weight
molecular
Active ingredientsAquaporins
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AQUAPORINS ACTUATORIT INCREASES THE LEVELS OF CUTANEOUS AQUAPORINS BY 36%
Power Hyaluronic has been formulated with xylitol and derivatives, molecules of natural origin thatguarantee perfect compatibility with the skin.These substances have proved (in-vitro) that they are capableof increasing the levels of aquaporins, particularly type 3 (AQP-3) mainly in the skin, by 36%*.
This family of substances also produces a very complete hydrating biological activityon the skin, and has testsproving its capacity to increase both dermal and epidermal water reserves, they improve the barrier functionand help to regulate the scaling process .
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*Stimulation of the level of GLYCOSAMINOGLYCANS (GAGs) and NMFIn-vitro (Anti-Aquaporin 3 (AQP-3)+Western-blot, Normal Human Keratinocytes (NHK), 4days incubation Dose:0,01%).
AQUAXYL™ increases protein expression of Aquaporin 3 (+36%) and ofβ-actin.
ACTIVE INGREDIENTS Aquaporins actuator
Aquaporins are membrane proteins that allow transporting basically water and othersolutes across the very inside of the cells (transcellular transport). Their quantity andquality allow water to be distributed and spread suitably across all parts of the middle and deeplayers of the epidermis.
IT INCREASES THE LEVELS OF CUTANOUS AQUAPORINS BY 36%
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Active ingredientsPolarised water
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Water is a transparent fluid, that is colourless, odourless, shapeless andtasteless. It adopts the shape of the container in which it finds itself and thecolour, smell and flavour of other things mixed with it. It is a universal solvent.
ESSENTIAL ELEMENT
WATER :
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Water covers two thirds of the Earth, and represents 70% of our body weight.Life on Earth - animal and plant life - would end if water did not exist.
ESSENTIAL ELEMENT
WATER :
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Thanks to the polar nature of water when a magnet is in contact with it for a considerable period of time, this water becomes magnetically charged and acquires new properties and new applications.
MAGNETISED WATER
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On the one hand polarised water increases the water’s conductivity and alkalinity.
NEW PROPERTIES
POLARISED WATER
Pure H2O Polarised H2O
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On the other hand, smaller clusters of water molecules are obtained, “packaged water”, which can allow greater water absorption in the cells.
POLARISED WATERNEW PROPERTIES
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Acidity and other digestive disorders: polarised water reduces the excess acidity in the digestive system.
Stones in the kidney: in scientific studies the use of polarised water is prescribed in patients suffering from kidney stones.
Low blood pressure and nervous system.
To accelerate the healing of wounds.
Therapeutic uses
POLARISED WATER
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LIPOSOMED POLARISED WATER
POLAROSOMES
Increases the absorption of polarised water via the cell walls.
Increases the penetration of polarised water towards the deepest layers of the skin.
The phospholipids relipidise the skin (improve the barrier effect).
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ACTIVE INGREDIENTS Polarised water
Complete skin hydration in three dimensiones that achieves better cell absorption:
Deep Dimension: The cell.
Thanks to the polarised water, it increases the absorption of water via the cell walls.
Middle Dimension: The deepest layers of the skin.
It is possible to take water to the deepest layers.
Superficial Dimension: Corneous Layer.
It is possible to reinforce the skin’s barrier function and prevent water loss.
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Salon treatment
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HA INTENSIVE CONCENTRATE
1,5%
INTENSIVE MOISTURISING EMULSION
0,25%
AQUAPORIN MASSAGE CREAM
POLARISED WATER
HA ULTRA HYDRATING GEL
0,25%
GEL MASAJEACUAPORINAS
Gel hidratante no graso para masaje facial en cabina.
Creado para acondicionar la piel y recuperar un nivel de hidratación óptimo. Con Xilitol y derivados, hidratantes que extructuran y armonizan la hidrodinámica interna de la piel.
Componentes principalesXilitol y derivados.
GEL ULTRAHUMECTANTE HA
0,25%
Gel humectante elaborado con elevado contenido en ácido hialurónico especialmente de alto peso molecular; tamaño que ayuda a hidratar y acondicionar la superficie de la piel.
Componentes principalesÁcido hialurónico de muy bajo y alto peso molecular (0,25%).
AGUA POLARIZADA
Solución con agua polarizada, proceso que permite empaquetar mayor cantidad de agua molecular en menos espacio. Vehiculizada en liposomas para mejorar su difusión en la piel.
Componentes principalesAgua polarizada liposomada.
EMULSIÓN HIDRATANTEINTENSIVA
0,25%
Crema hidratante para el rostro, con elevado contenido en ácido hialurónico de muy bajo y alto peso molecular.
Componentes principalesÁcido hialurónico (0,25%(. Extracto de girasol, Xilitol y derivados..
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HA DYNAMICPROFESSIONAL PROGRAMME
Apply 2 ml. of HA INTENSIVE CONCENTRATE and spread over the face and neck with upward massage strokes or using the MESOSCIENCE BY SKEYNDOR equipment, 5 minutes on negative
polarity.
Remove eye and lip make-up with the specific SKEYNDOR eye make-up remover. Clean and
tone the face, neck and cleavage using the appropriate SKEYNDOR hygiene line.
In order to facilitate absorption of the active ingredients, exfolliate the skin with the most appropriate SKEYNDOR peeling, preferably, GLYCO-30 or SK-ENZYME PEELING.
1 2
3 4
5 6
Apply the AQUAPORIN MASSAGE GEL with a soft, modelling massage. Optionally, help the product penetrate the skin using the MESOSCIENCE equipment, using the ELECTROPORATION current.
Then spread an amount of HA ULTRA HYDRATING GEL and help it penetrate the skin using the POLARISED WATER. Apply the rest of the gel as a fine mask and leave for 20 minutes.
Use a damp sponge to completely remove any product excess, and tone the skin. End the treatment with the INTENSIVE MOISTURISING EMULSION.
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HA DYNAMICPROFESSIONAL PROGRAMME
The POLARISED WATER is applied in two key moments of the treatment:
Step 3: together with the HA INTENSIVE CONCENTRATE with the aim of improving the
penetration of the HA of very low molecular weight.
Step 5: together with the HA ULTRA HYDRATING GEL with the aim of hydrating the stratum corneum and improving the attachment of the high molecular weight HA.
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HA DYNAMICPROFESSIONAL PROGRAMME
Applying a facial massage using selenite stones
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In the massage stage with the HA ULTA HYDRATING GEL, relaxing strokes are to be used on the skin, with the help of two selenite stones.
Selenite is a mineral associated with water. It is one of the first minerals to be formed by the
evaporation of sea water (lakes and closed waters).
.
Presentation: set of two selenite stones.
Home treatment
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INTENSIVE MOISTURISING CREAMDAILY HYDRODYNAMICTREATMENT
EFFECTS· 100% ultramoisturising*.· Provides 24 hours of continuous hydration*.· Improves the appearance of wrinkles caused by dehydration*.· Improves the appearance of micro-relief and cutaneous wrinkles*.
ACTIVE SUBSTANCES· 0.25% hyaluronic acid with a very low and a very high molecular weight.· Sunfl ower extract.· Xylitol and its by-products.
Presented in two different textures, dependingon the skin type:· Dry to very dry skins: rich texture.· Normal to combined skins: lighter, non-oily texture.
Presented in 50 ml jar
*Clinical and in-use test on 20 volunteers. Home cosmetic treatment (1 week): intensive moisturising cream oremulsion + moisturising booster + deep moisturising mask. 45
MOISTURISING BOOSTERA HIGH-PERFORMANCEBOOSTER TREATMENT
EFFECTS· 100% ultramoisturising*.· Provides 24 hours of continuous hydration*.· Improves the appearance of wrinkles caused by dehydration*.· Enhances the benefi ts of the daily moisturising cream*.· Improves the appearance of the cutaneous micro-relief*.
ACTIVE SUBSTANCES· 1% hyaluronic acid with a very low and a very high molecular weight.· Xylitol and its by-products.
Presented in a 30ml dropper bottle
46*Clinical and in-use test on 20 volunteers. Home cosmetic treatment (1 week): intensive moisturising cream oremulsion + moisturising booster + deep moisturising mask.
1. What is a booster?
Booster cosmetics are those products which, when applied, manage to increase the efficiency of the productsused afterwards, they act as amplifiers.For example, make-up can be fixed, bases can be made to last longer,the skin can absorb treatment creams better or, improve or complement their effect.
2. Can we apply make-up after Power Hyaluronic Moisturising Booster?
Yes, you can. The Booster + Cream + Make-up combination has been tested, and no “erasing” occurs. The finalresult will depend largely on the skin type and the amount of product applied.
MOISTURISING BOOSTER
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3. What is the difference between a serum and a booster?
The serum is a complete, balanced cosmetic. Technically it does not need other cosmetics to carry out its cosmeticfunction.
The booster is a cosmetic that is very specialised in a specific function, e.g. hydrating, but it needs other cosmetics tobe able to adapt to the needs of consumer skins, particularly in terms of texture and comfort.
Both the serum and the booster share these 4 key points:
High concentration of active ingredients
Immediate absorption
Fast action
Deep repair:
MOISTURISING BOOSTER
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4. Does it adapt well to all skin types?
In principle, yes. In alipic skins or skins lacking grease, it is advisable to combine it with a cream.
In more mixed skins it is advisable to apply it on its own, preferably at night.
5. On which skin conditions can it be used?
Slightly aged skins with superficial dehydration wrinkles.
Prevent cutaneous dehydration in dry environments/climates.
Average or deep dehydration.
MOISTURISING BOOSTER
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DEEP MOISTURISING MASK
EFFECTS· Improves hydration in the areas that most need it.· 100% ultramoisturising*.· Leaves skin comfortable and soft*.· Improves the appearance of the cutaneous micro-relief*.
ACTIVE SUBSTANCES· 0.25% hyaluronic acid with a very low and a high molecular weight.· Polarised water encapsulated in liposomes.· Xylitol and its by-products.
Presented in a 50ml tube.
A SELECTIVE CHRONOPROGRAMMEDTREATMENT
50*Clinical and in-use test on 20 volunteers. Home cosmetic treatment (1 week): intensive moisturising cream oremulsion + moisturising booster + deep moisturising mask.
Tested results
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Marketing support
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Display
The display measurements are normal. Versatile size for locating either in the salon window, or
inside (floor or wall).
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Display with:Tester Moisturising Booster sale size
30 ml.It is delivered to the sales outlet with all the material
inside the same packaging case.
The Moisturising Booster tester is marked with :
TESTER · NOT FOR RETAIL
Display Stand(display format - 3 page stand)
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The display includes a leaflet with assembly guide. You only have to insert the PVC part into the front of the corresponding
display. The Moisturising Booster tester is placed on top of this part.
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End consumer samples
• Intensive Moisturising Cream Dry to Very Dry Skins.• Intensive Moisturising Emulsion Normal to Mixed skins.•Moisturising Booster.
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Catalogue
Catalogue
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The professional catalogue includes a fold down section on the inside cover containing the technical file andthe step by step application guide for the professional program.
The technical file will only be available in ENGLIGH in digital format.58
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Leaflet
Support information
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Main commercial arguments on cream differences
Power Hyaluronic Power C+ Nat Def 24 h Aquatherm
Recommended age From 20 years old From 25 years old From 30 years old From 20 years old
Skin type
DEHYDRATED SKINS AND/OR SKINS WITH SMALL DEHYDRATION WRINKLES
DULL, LIFELESS SKINSSKINS WITH AVERAGE
DEHYDRATIONSENSITIVE SKIN
Active ingredients
Hyaluronic acid with very low and high molecular weight,
Xylitol and derivativesLiposomed polarised water
High absorption Vitamin CPomegranite extract
Pentavin, ceramides, L-PCA, Hydgroplex
Thermal waterPre-biotic oligosaccharides
Ceramides
Benefit
Rebalances the skin’s natural hydrodynamics.
24 hours extra moisturising
Provides radiance and revitalises the skin 24 h hydration
Rebalances sensitive or reactive skins.
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Based on the surgical techniques of implanting hydrocolloid gels for facial filling. It is a hyaluronic acid modified for cosmetic application, capable of penetrating and swelling
up to 30 times its size, filling up empty spaces.
Differences between the HA of Power Hyaluronic and Corrective
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Corrective: HA cosmetic fillling (Filling SpheresTM by BASF).It is a cosmetic technology developed to perform non-invasive filling treatments, complementing plastic surgery methods. It uses average and high molecular weightHAs linked and compacted in the form of dehydrated microspheres.Thanks to its size, it can penetrate the middlelayer of the epidermis. There, it captures water and swells up to thirty times its original size adding volume.
This process takes place during the 10 minutes after application, and it is maintained several days depending on thenumber of applications. Formulated to the recommended doses by the manufacturer.
Power Hyaluronic: Hyaluronic acid with very low and high molecular weight, With the usage doses they produceextra-moisturising activity.Due to their size they reach the dermis or do not penetrate, respectively.They preventdehydration and activate the synthesis of new hyaluronic acidThis process takes place 10 minutes after applicationand lasts at least 24 hours. Formulated to the highest market doses (between x10 and x100 times more than an averagecosmetic).
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