Earn a Nobel Prize in

Physiology or Medicine by 2037

For Malaysia

Mark Lee, SM MIT ‘99 mlee@alum.mit.edu

September 2014

The 2013 Chemistry Nobel Prize Was Won w/Computing

http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2013/press.html

Today the computer is just as important a tool for chemists as the test tube. Simulations are so realistic that they predict the outcome of traditional experiments. Chemists used to create models of molecules using plastic balls and sticks. Today, the modelling is carried out in computers. In the 1970s, Martin Karplus, Michael Levitt and Arieh Warshel laid the foundation for the powerful programs that are used to understand and predict chemical processes. Computer models mirroring real life have become crucial Aided by the methods now awarded with the Nobel Prize in Chemistry, scientists let computers unveil chemical processes, such as a catalyst’s purification of exhaust fumes or the photosynthesis in green leaves.

Can Computing Drive A Future Nobel Prize in Physiology or Medicine?

Malaysians Living and Working in Malaysia

(by 2037)

EU Funds a US$1.6 billion Human Brain Project

https://www.humanbrainproject.eu/

The Human Brain Project kicked off Oct. 7, ‘13 at a conference in Switzerland. Over the next 10 years, about 80 science institutions and at least 20 government entities in Europe will figure out how to make that computer brain. The project will cost about $1.6B in U.S. dollars.

Striving Towards a Nobel Prize

Earn MY’s 1st Nobel Prize within 23 Years (by 2037)

Enter College

PhD

10

18 Grow Before

Discovery

30

18 5 Year

Research

40 Years For a Fresh Permata Pintar Alum

23 Years For Research & Award

Saves 17 Years

2037

http://im1.biz/albums/userpics/10001/V5_I4_A3_NobelMed105.htm

12

Earn the Nobel Prize in Physiology or Medicine by 2037

"for the development of multiscale models

for complex chemical systems“

2013 2037

"for the development of multiscale models

for complex biological systems“

creativity intelligence

25 Years

Average Time between Discovery

& Prize

18 Years

Computing

MY 1 Nobel 2037: Muslim Nobel Science Laureates + 1

http://en.wikipedia.org/wiki/List_of_Muslim_Nobel_Laureates

Physics, 1979 Abdus Salam

Pakistan

Chemistry, 1999 Ahmed Zewail

Egypt

? Physiology or Medicine

None as of 2014

Earn the Nobel Prize for Physiology or Medicine by 2037

Place Holder

1st Malaysian Nobel Laureate

1st Muslim Nobel Laureate For Physiology or Medicine

1st Female Muslim Nobel Laureate for

Sciences

Physiology or Medicine By 2037

Malaysia’s Moon Shot

Google X: Moonshots Focus Upon 10X Improvement

Larry Page’s Gospel of 10X

http://www.wired.com/business/2013/01/ff-qa-larry-page/

The way Page sees it, a 10 percent improvement means that you’re basically doing the same thing as everybody else. You probably won’t fail spectacularly, but you are guaranteed not to succeed wildly. That moon-shot mentality is the basis of Google X, which the company established in early 2010 to identify and implement once-impossible sci-fi fantasies: Hail Mary projects like the self-driving car. Or Google Glass, a wearable computing system. Or an artificial brain, in which a cluster of computers running advanced algorithms learn from the world around them, much like humans do. Page: It’s not easy coming up with moon shots. And we’re not teaching people how to identify those difficult projects. Where would I go to school to learn what kind of technological programs I should work on? You’d probably need a pretty broad technical education and some knowledge about organization and entrepreneurship. There’s no degree for that. Our system trains people in specialized ways, but not to pick the right projects to make a broad technological impact.

Malaysia’s Moon-Shot Solves For “Greater Creativity”

Yes: The Need to Nurture

Creativity for the World’s 7 Billion Population

Cross-Disciplinary Solution: Neuroscience, Computer Science

& Psychology

Work in Progress

https://www.solveforx.com/moonshots/new/

Creativity versus Intelligence

Nobel Prize in Physiology or Medicine

by 2037 For Malaysia

The Center for Brains, Minds and Machines (CBMM) is a multi-institutional collaboration,

headquartered at Massachusetts Institute of Technology (MIT) with managing partners at

Harvard University and Cornell University. http://cbmm.mit.edu/

MIT, Harvard & Cornell Host a US$25M NSF-Funded Study of Intelligence

4 Inter-Disciplinary Research Themes

http://web.mit.edu/press/2013/center-for-brains-minds-and-machines.html http://www.kurzweilai.net/nsf-awards-25-million-to-mit-based-center-to-advance-brain-understanding

1. the integration of intelligence, including vision, language and motor skills;

2. circuits for intelligence, which will span research in neurobiology and electrical engineering;

3. the development of intelligence in children; 4. social intelligence.

The award will also help train the next generation of scientists and engineers. A summer school program, technical workshops and online courses are planned to create a new community of interdisciplinary researchers fluent in the study of intelligence.

Provides a Nobel-Worthy Research Opportunity

But Creativity & Intelligence

Are Not The Same

Creativity is NOT THE SAME as Intelligence

http://hbswk.hbs.edu/item/6760.html WIRED ALSO

Intelligence 50% -85% Inheritable

Creativity 25% - 40% Inheritable

The world is not limited by IQ. We are all limited by bravery and creativity

Astro Teller, Head of Google X

≠

Cultivating Creativity, which can be Learned (only 25%-40% inheritable)

http://hbswk.hbs.edu/item/6760.html

Six other creativity studies of identical twins confirm the Reznikoff et al. result: roughly 25 percent to 40 percent of what we do innovatively stems from genetics. … roughly two-thirds of our innovation skills still come through learning—from first understanding the skill, then practicing it, and ultimately gaining confidence in our capacity to create.

Testing twins aged fifteen to twenty-two, they found that only about 30 percent of the performance of identical twins on a battery of ten creativity tests could be attributed to genetics.

Creativity Surpasses Intelligence

… Albert Einstein was a good friend, too. But none of them had a mind as quick and acute as Jansci [John] von Neumann. I have often remarked this in the presence of those men and no one ever disputed me. ... But Einstein's understanding was deeper even than von Neumann's. His mind was both more penetrating and more original than von Neumann's. .... Einstein took an extraordinary pleasure in invention. Two of his greatest inventions are the Special and General Theories of Relativity; and for all of Jansci's brilliance, he never produced anything as original.

More Creative Than

Smarter than

von Neumann

Imagination is More Important than Knowledge Einstein

Every great advance in science has issued from a new audacity of imagination. John Dewey

It's kind of fun to do the impossible. Walt Disney

Imagination is more important than knowledge

Logic will get you from A to B. Imagination will take you everywhere

Can Imagination

be More Important than Intelligence?

What is Creativity?

Creativity: Connecting Things (which implies a Process and a Graph)

How Can Would-Be Creatives

Connect Things (Ideas) ?

What are the Possible • Creativity Process(es)? • Serendipity Graphs?

Connection: Foundation for Genius Solo Group Symbiotic

Solo Group Symbiotic

Within 1 Human Between Humans Between Humans & Machines

?

Solo Genius Connecting within 1 Mind

Albert Einstein … had an unusually well-connected brain. The new insight was gleaned from

a recently discovered set of 14 photographs of Einstein’s brain taken just after his autopsy.

Group Genius Connecting Between Complementary Minds

James Watson Francis Crick

Symbiotic Genius Connecting Human Imagination & Machine Intelligence

Licklider also realized that interactive computers could provide more than a library function, and could provide great value as automated assistants. He captured his ideas in a seminal paper in 1960 called Man-Computer Symbiosis, in which he described a computer assistant that could answer questions, perform simulation modeling, graphically display results, and extrapolate solutions for new situations from past experience. Like Norbert Wiener, Licklider foresaw a close symbiotic relationship between computer and human, including sophisticated computerized interfaces with the brain.

Striving Towards Creativity & Genius

Nobel-Worthy Creativity Research Opportunity That Complements Intelligence Research

US$25M Center

for Brains, Minds and

Machines

Creativity Intelligence Complement

World-Leading Opportunity

for Nobel-Worthy

Research on Creativity

Nobel-Worthy Creativity Research Opportunity That Complements Intelligence Research

US$25M Center

for Brains, Minds and

Machines

Creativity Intelligence Complement

Nobel Laureate@ Columbia Harvard, MIT

MY & SG Universities All Participants:

From top 50 Research Institutions

5 Year US$25 Million Brain and Mind Center for

Creativity and Genius

Opportunity for Nobel-Worthy Global Leadership in Creativity Research Symbiotic Genius

€43M/3Years

?

$0

Dartmouth Finds a Neurological Basis for Imagination

http://www.psychologytoday.com/blog/the-athletes-way/201309/the-right-brain-is-not-the-only-source-creativity

A Sep 2013 study from scientists at Dartmouth College paints a fuller picture of this mental workspace by imaging the brain regions involved with mentally manipulating images, like the shapes above.

… imagination stems from a widespread network of brain areas that collectively manipulate ideas, images and symbols. This "mental workspace" had been theorized before, but this study provides new empirical evidence. The findings were published on September 16, 2013 in the journal Proceedings of the National Academy of Sciences. The study is titled "Network Structure and Dynamics of the Mental Workspace.

Symbiotic Genius Can Change the World

What is a Meta-Idea?

2nd Machine Age

Prior Meta-Ideas That Changed the World

USA 19th Century:

Land-Grant Schools 20th Century: Peer-Review

UK 17th Century:

Patents & Copyrights

MY Develops the “Symbiotic Genius” Meta-Idea To Drive Economic Growth

USA 19th Century:

Land-Grant Schools 20th Century: Peer-Review

UK 17th Century:

Patents & Copyrights

Malaysia 21st Century:

Symbiotic Genius?

Symbiotic Genius Boosts Innovation

Mass Innovation Mass Creativity Mass Flourishing

Symbiotic Genius Human Imagination

With Machine Intelligence

Digital Economy Modern Society “See Like a Genius”

Dartmouth Research “Imagination” Neuroscience

Symbiotic Genius (See Like a Genius)

3rd Digital Age With

Pervasive Prosperity

Physio/Med Malay Psyche

Muslim Nobel Laureate

2013-2037

Why Strive for Malaysia’s 1st Nobel Prize by 2037?

Timeline Not to Scale

Societal Impact

S1

Pioneers Google: Search

Facebook: Social

Platform Solution Graph

Serendipity Graph

1st Machine Age Muscle

2nd Machine Age Mind

1st Digital Age Process Information

2nd Digital Age Provide Intelligence

3rd Digital Age Provoke Ideas

Supplement Human Intel

Substitute Human Intel

Widespread Job Loss

Pocket Prosperity

Cultivate Symbiotic Genius* Human Imagination w/Machine Intel

(meta-idea)

Pervasive Prosperity

*Genius Solo Group Symbiotic

Present Potential

Opposing Futures

3rd Digital Age

S3

Mass Flourishing

Funding Symbiotic Genius

Research

Funding a US$25M Research Center

http://web.mit.edu/press/2013/center-for-brains-minds-and-machines.html http://www.kurzweilai.net/nsf-awards-25-million-to-mit-based-center-to-advance-brain-understanding

1. the integration of creativity, including vision, language and motor skills;

2. circuits for creativity, which will span research in neurobiology and electrical engineering;

3. the development of creativity in children and adults; 4. Social & Symbiotic creativity. 5. Others?

The award will also help train the next generation of scientists and engineers. A summer school program, technical workshops and online courses are planned to create a new community of interdisciplinary researchers fluent in the study of creativity.

Brain and Mind Center for Creativity and Genius

The Center for Brains, Minds and Machines (CBMM) is a multi-institutional collaboration,

headquartered at Massachusetts Institute of Technology (MIT) with managing partners at

Harvard University and Cornell University. http://cbmm.mit.edu/

MIT, Harvard & Cornell Host a US$25M NSF-Funded Study of Intelligence

No Comparable US-Govt Funded Initiative for Creativity

Explaining Creativity 2nd Ed, 568 pages

EU Allots €43M for Computational Creativity (2013 onwards for 3 years)

http://prosecco-network.eu/

EU Computational Creativity Funding Goals

EU Computational Creativity Funding Goals

Next Steps

1. Explore the Potential for World-Class First-of-its-Kind Research on Creativity & Genius that Blends Human and Machine Capabilities

2. Use the “Race With Machines” approach that originated with MIT Professor Erik Brynjolfsson, and detailed in his Jan 2014 book “The Second Machine Age”

3. Solicit US$25M (=RM$80M) funding from the Government to jumpstart the “Symbiotic Genius” Research Center

Mark Lee

1. MIT M.S. graduate with coursework at Harvard Law School and Harvard Business School

2. CEO of a Startup with its R&D in Singapore 3. Co-filed a patent with NUS Computer Science

Faculty – see next slide

MIT Professor Erik Brynjolfsson (“2nd Machine Age”) used Mark Lee’s MS thesis as a case study for his MIT Sloan course

http://www.directorypatent.com/WO/WOZZSLASHZZ2009ZZSLASHZZ061283.html

Co-Filed Patent with NUS

Thank You!

Mark Lee, MIT ‘99 mlee@alum.mit.edu

September 2014