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ICMRJuniorResearchFellowshipExamination2015:LifeSciences

INDIANCOUNCILOFMEDICALRESEARCH

ModelQuestionPaper01

1. Theaveragesizeof70Sribosomesofprokaryotesare:a. ~200Åb. ~250Å

c. ~290Åd. ~303Å

2. Whichofthefollowingisanexampleforchemolithotroph?a. Acidithiobacillus

ferrooxidansb. Nitrosomonas

c. Nitrobacterd. Alloftheabove

3. Whichofthefollowingisanexamplefordenitrifyingbacteria?a. Nitrosomonasb. Nitrobacter

c. Pseudomonadsd. Alloftheabove

4. Who introduced the group Archaea for a group of prokaryotes on the basis ofphylogeneticanalysisof16SrRNA?

a. RogerStanierb. CarlWoese

c. C.B.vanNield. TheodorEscherich

5. Whodiscoveredendoplasmicreticulum?a. Keithporterb. KonstantinMereschkowsky

c. CamilloGolgid. GeorgeEmilPalade

6. Acrosomeofspermcellisamodified________.a. Lysosomeb. Peroxisome

c. Golgid. Noneofthese

7. Calmodulin is a calcium‐binding messenger protein of eukaryotic cells. A singlecalmodulinproteinatatimecanbind_______Ca2+ions.

a. 1b. 2

c. 3d. 4

8. TheH–O–Hbondangleofwatermoleculeis____________.a. 103.5o

b. 104.5oc. 105.5o

d. 109.5o

9. Atatimeasinglewatermoleculecanform_______hydrogenbondswithotherwatermolecules

a. 1b. 2

c. 3d. 4www.ea

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10. pHbelowpI,aminoacidswillbe___________.a. Cationicb. Anionic

c. Nocharged. Netchargezero

11. Whichofthefollowingisanexampleforaribozyme?a. Transpeptidaseb. Glutamyltranspeptidase

c. Peptidyltransferased. Alloftheabove

12. ThenebenkernofDrosophilaspermcellisamodified________.a. Nucleusb. Mitochondria

c. Lysosomed. Golgi

13. WhichofthefollowingchromosomalaberrationcausesPatausyndromeinhuman?a. Trisomy21b. Trisomy13

c. Trisomy18d. Trisomy8

14. Theonlyantibodyabletocrossplacentatogivepassiveimmunitytothefetus_____.a. IgAb. IgE

c. IgGd. IgM

15. Whichofthefollowingantibodyisinvolvedinallergicreactions?a. IgAb. IgE

c. IgGd. IgM

16. Antibodypresentintearsandsalivais:a. IgAb. IgE

c. IgGd. IgM

17. Anautoimmunediseasethataffectsthethyroidglandis_________a. Tay–Sachsdiseaseb. Addison'sdisease

c. Graves'diseased. Behçet'sdisease

18. How many different types of gametes can be produced by an organism withgenotypeAaBBCCDdEe?

a. 4b. 6

c. 8d. 10

19. Weil–Felixtestisusedforthediagnosisof________a. Rickettsialinfectionb. Pertussis

c. Cholerad. Africansleepingsickness

20. PhiX‐175isa___________.a. ssRNAvirusb. dsRNAvirus

c. ssDNAvirusd. dsDNAvirus

21. DiploidchromosomenumberofPantroglodytesisa. 42b. 44

c. 46d. 48

22. The20differentaminoacidsintheproteinarenormallycodedby:a. 60codons b. 61codonswww.ea

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c. 62codons d. 63codons23. Whichofthefollowingisthecausativeagentoffowlcholera?

a. Vibriocholerab. Escherichiacoli

c. Salmonellapullorumd. Pasteurellamultocida

24. Whichofthefollowingaminoacidsiscodedbymaximumnumberofcodons?a. Leucineb. Tryptophan

c. Valined. Alanine

25. Aluelementsarea. Transposonsb. Retroposons

c. SINESsd. LINEs

26. FortheconstructionofRamachandran’splotvaluesofPsiandPhiareplotted.ThevalueofPhiistherotationanglearound:

a. N–Cαbondb. Cα–Cbond

c. C–Nbondd. N–Hbond

27. Which of the following causes deviation in Hardy‐Weinberg equilibrium in apopulation?

a. Randommatingb. Smallpopulationsize

c. Lackofselectionpressured. Nomutation

28. Whichofthefollowingaminoacidsinaproteinformsa‘saltbridge’?a. Tyr–Pheb. Cys–Cys

c. Lys–Glud. Ala–Val

29. Bunchytopdiseaseofbananaistransmittedbythevector:a. Ferrisiavirgatab. Aphisgossypii

c. Thripstabaccid. Pentalonianigronervosa

30. Thesourceofdwarfinggenesinwheatis____a. Ganga101b. Norin10

c. Dee‐geo‐woo‐gend. Sonalika

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