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Honors Biology
Growth and Development and Cellular Inheritance
Introduction
Asexual Reproduction
Sexual Reproduction
Growth and Development
2n = 20
A chicken has 78 Chromosomes in its Somatic Cells:
• How many chromosomes did the chicken inherit from each parent?
• How many chromosomes are in each of the chicken’s gametes?
• How many chromosomes will be in each somatic cell of the chicken’s offspring?
• How many chromosomes are in a “set”
• Which came first…chicken or egg?
http://www.youtube.com/watch?v=m73i1Zk8EA0&feature=related
How many chromosomes are shown in this diagram? How many chromatids are shown?
Compare the number of cells in interphase, prophase, metaphase, anaphase or telophase in these two areas. Explain differences.
Apical m
eristem
Zone of elongation
Yeast Life Cycle
Budding Pattern
Yeast Mating Types
Uncontrolled Growth
Angiogenesis
Apoptosis
“Immortal Cells”
Telomerase
Metastasis
Immune System
What would happen if you performed this experiment with cancer cells?
Henrietta Lacks
HeLa cells
Stem Cell Sources
Embryonic Stem Cells (ES)
In Vitro Fertilization
Louise Brown – Birthday 1978
Nuclear Transfer
Adult Stem Cells
iPS
IPS
http://www.youtube.com/watch?v=cPvidAvzmx0&feature=related
http://www.youtube.com/watch?v=fGNchPdlaGU&NR=1&feature=fvwp
STAP cells
Haruko Obokata.
Controversial therapy.Mitochondrial DNA replacement could help carriers of severe disease have healthy children.
G Vogel Science 2014;343:827-828
Published by AAAS
Meiosis
Honors Biology
Aneuploidy Article
Honors Biology
General Background Questions:
• What is the genome, transcriptome and the proteome?
• What is aneuploidy?
Experiment Questions:
• What was the “conundrum” they identified in the Introduction?
• What are the two experimental questions?
Meiosis Question:
• Diagram why meiosis with odd ploidy (3N or 5N) would produce aneuploids.
Key Findings• What are key
findings from: ab, ef, and gh?
A16
Why is strain A16 a good strain to focus on for experimental question?
ATR1
• What are: C-some XIII, ATR1, 4-NQO, and Strain A16?
• What is their relationship?
Proteome & Transcriptome:
Gene dosage effect or dosage compensation
Aneuploidy has global and complex effects on both the transcriptome and proteome levels, and that an increase in stress gene expression is not an obligate
property of aneuploidy strains.