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FDA’s warning against Dick’s Hard Up Dr. P.Naina Mohamed Pharmacologist

FDA's warning against Dick’s Hard Up

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On 2nd June 2014, The Food and Drug Administration (FDA) is advising consumers not to purchase or use “Dick’s Hard Up”. Dick’s Hard Up is a product promoted and sold for sexual enhancement on various websites and in some retail stores. FDA laboratory analysis confirmed that “Dick’s Hard Up” contains tadalafil.

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Page 1: FDA's warning against Dick’s Hard Up

FDA’s warning against

“Dick’s Hard Up ”

Dr. P.Naina MohamedPharmacologist

Page 2: FDA's warning against Dick’s Hard Up

Introduction On 2nd June 2014, The Food and Drug

Administration (FDA) is advising consumers not to purchase or use “Dick’s Hard Up”.

Dick’s Hard Up is a product promoted and sold for sexual enhancement on various websites and in some retail stores.

FDA laboratory analysis confirmed that “Dick’s Hard Up” contains tadalafil.

Page 3: FDA's warning against Dick’s Hard Up

Possible Mechanism of Action

Page 4: FDA's warning against Dick’s Hard Up

Interaction with Nitrates

Page 5: FDA's warning against Dick’s Hard Up

Interaction with Protease Inhibitors (Antiretrovirals)

Page 6: FDA's warning against Dick’s Hard Up

Interaction with CYP3A4 Inhbitors

Page 7: FDA's warning against Dick’s Hard Up

Conclusion

FDA warns the Consumers should stop using this product immediately and throw it away. 

FDA advises the Consumers who have experienced any negative side effects should consult a health care professional as soon as possible. 

FDA announces to the public of a growing trend of dietary supplements or conventional foods with hidden drugs and chemicals.  These products are typically promoted for sexual enhancement, weight loss, and body building, and are often represented as being “all natural.” 

FDA claims that they are unable to test and identify all products marketed as dietary supplements on the market that have potentially harmful hidden ingredients. 

FDA advises the Consumers to exercise caution before purchasing any product in the above categories.

Page 8: FDA's warning against Dick’s Hard Up

References http://www.fda.gov/Drugs/ResourcesForYou/Consumers/

BuyingUsingMedicineSafely/MedicationHealthFraud/ucm399603.htm?source=govdelivery&utm_medium=email&utm_source=govdelivery

Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e Laurence L. Brunton, Bruce A. Chabner, Björn C. Knollmann

Harrison's Online Featuring the complete contents of Harrison's Principles ofInternal Medicine, 18e Dan L. Longo, Anthony S. Fauci, Dennis L. Kasper, Stephen L. Hauser, J. Larry Jameson, Joseph Loscalzo, Eds.

Hurst's The Heart, 13eValentin Fuster, Richard A. Walsh, Robert A. Harrington

Basic & Clinical Pharmacology, 12e Bertram G. Katzung, Susan B. Masters, Anthony J. Trevor

Clinician's Pocket Reference, 11eLeonard G. Gomella, Steven A. Haist

Page 9: FDA's warning against Dick’s Hard Up

References http://www.nlm.nih.gov/medlineplus/

druginfo/meds/a604008.html http://www.rxlist.com/cialis-tadalafil/drug-

2.htm http://www.medicinenet.com/tadalafil/

article.htm http://www.drugs.com/tadalafil.html