SOLOMON SUDHAKAR MAGAPU JOSEPH KAYYALAKALAYIL DAVID BAKTHAVATCHALAM LOGANATHAN AYILYA VIRULENCE GENES OF Staphylococcus aureus ISOLATED FROM HEALTHY PERSONS Staphylococci are primary parasites of human beings and animals, colonizing the skin,skin glands and mucous membranes.Generally their presence is not clinically significant, but they sometimes act as opportunistic pathogens and cause infection in debilitated or immunodeficient subjects. About 10-30 per cent of healthy persons carry Staphylococci in the nose, perineum and also on the hair.It is one of the five important organisms that cause nosocomial infections.It is present as a long term carriage organism in approximately 30% of the world population.Hence the chance of it causing infection in normal and immuno-compromised individuals is high.The organism is capable of causing both deep seated and superficial infections and recent studies show that the molecular types isolated from superficial sites and deeper tissues are distinctly different.The capability to establish an infection greatly depends on how they invade and get entry to the deeper tissues.This may be due to the presence of various virulence factors possessed by the organism.In the present study an attempt is made to demonstrate the virulence genes (like coa gene) of S.aureus isolated from healthy Carriers. SOLOMON SUDHAKAR MAGAPU Dr.M.Solomon Sudhakar has over 13 years of experience in managing research activities, teaching assignments, coordinating with team and enhancing process operations in Biotech. Demonstrated competence in executing a wide gamut of functions.A thorough professional with a proactive attitude. www.magapusolomonsudhakar.com 978-3-659-33709-3

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SOLOMON SUDHAKAR MAGAPUJOSEPH KAYYALAKALAYIL DAVID

BAKTHAVATCHALAM LOGANATHAN AYILYA

VIRULENCE GENES OFStaphylococcus aureus

ISOLATED FROM HEALTHYPERSONS

Staphylococci are primary parasites of human beings and animals,colonizing the skin,skin glands and mucous membranes.Generally theirpresence is not clinically significant, but they sometimes act asopportunistic pathogens and cause infection in debilitated orimmunodeficient subjects. About 10-30 per cent of healthy persons carryStaphylococci in the nose, perineum and also on the hair.It is one of thefive important organisms that cause nosocomial infections.It is present as along term carriage organism in approximately 30% of the worldpopulation.Hence the chance of it causing infection in normal andimmuno-compromised individuals is high.The organism is capable ofcausing both deep seated and superficial infections and recent studiesshow that the molecular types isolated from superficial sites and deepertissues are distinctly different.The capability to establish an infection greatlydepends on how they invade and get entry to the deeper tissues.This maybe due to the presence of various virulence factors possessed by theorganism.In the present study an attempt is made to demonstrate thevirulence genes (like coa gene) of S.aureus isolated from healthy Carriers.

SOLOMON SUDHAKAR MAGAPU

Dr.M.Solomon Sudhakar has over 13 years ofexperience in managing research activities, teachingassignments, coordinating with team and enhancingprocess operations in Biotech. Demonstratedcompetence in executing a wide gamut offunctions.A thorough professional with a proactiveattitude. www.magapusolomonsudhakar.com

978-3-659-33709-3