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What is the large cell?
A myeloblast is a large cell, 12-20 microns in diameter, with anucleus that takes up most of the cell.
Nuclear chromatin is fine, with little condensation and fairlyhomogenous in appearance.
Nucleoli may vary in number and are apt to be large. The scantycytoplasm is blue without granules.
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What is this cell?
A promyelocyte may be the same size as the myeloblast or evenlarger. Unlike the myeloblast, the promyelocyte's cytoplasmcontains large black or purple granules. Nucleoli may bepresent.
What is this cell?
The myelocyte is smaller than the myeloblast or thepromyelocyte. Unlike the myeloblast and promyelocyte, themyelocyte's cytoplasm contains specific granules, i.e. brick-red(eosinophils), large, blue-black granules (basophils), and lilacgranules (neutrophils).
The nucleus still has a round or oval shape and no nucleoli arepresent. Myelocytes are not seen on a normal peripheral bloodsmear.
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What is this cell?
Metamyelocytes (Juvenile) are smaller than the myelocytes.There is more marked clumping of the nuclear chromatin sothat the nucleus becomes much denser, takes up less than half the cell volume, and is indented (k idney-shaped).
What is this cell?
The band (stab) is similar to the metamyelocyte but the band is
smaller and has a horseshoe-shaped nucleus.
The cytoplasm may contain fine lilac granules (neutrophilic),brick-red granules (eosinophilic) or large blue-black granules(basophilic).
Bands normally account for 0-5% of the total leukocyte count incirculating blood of the adult.
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What is this cell?
Metamyelocytes (Juvenile) are smaller than the myelocytes.There is more marked clumping of the nuclear chromatin sothat the nucleus becomes much denser, takes up less than half the cell volume, and is indented (k idney-shaped).
What is this cell?
The band (stab) is similar to the metamyelocyte but the band issmaller and has a horseshoe-shaped nucleus.
The cytoplasm may contain fine lilac granules (neutrophilic),brick-red granules (eosinophilic) or large blue-black granules(basophilic).
Bands normally account for 0-5% of the total leukocyte count incirculating blood of the adult.
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What is this cell?
A segmented neutrophil (poly) is approximately 12-14 micronsin diameter. This is the final stage of granulocytic development.Normal polys generally have two to five lobes.
Hypersegmented polys, containing six or more lobes, arecharacteristically seen in megaloblastic anemias.
Polys normally account for 45-75% of a normal differential in anadult.
What is this cell?
A monocyte has blue-gray cytoplasm and a lobulated nucleus.It's distinguished from other leukocytes by the folding-over of the nuclear lobe (fetal-shaped). 4-11% in a normal blooddifferential.
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What is this cell?
Basophils are present in small numbers (0-3%) in a normalblood smear. Dark coarse granules and indistinct nucleus arecharacteristic. The basophil is a source of histamine andinvolved with allergic and inflammatory/immune responses.Increased numbers are seen in myeloproliferative disorders, e.g.chronic myelogenous leukemia and polycythemia vera.
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