Subject Index
aberration rates 47, 48, 113 accidents, actually occured in nuclear
power plants 89 Idaho Falls 1961 90 Los Alamos 1945 89 Los Alamos 1946 89 Los Alamos 1958 89 Oak Ridge 1958 89 Vinca, Yugoslavia 1958 90
air traffic 9 collective dose equivalent of the
world population 9 dose rate per person using super
sonic aircraft transport 9 animal studies on the protection of ma
lignant tissues by radioprotective drugs 122
annual limit of intake (ALI) 32,36-41 antimutagenic efficacy of radioprotec
tors 113 against chromosome damage 113,
114 against lethal mutations 113 decrease induction of abberations
114 areas with increased terrestrial radia
tion 3,7
BEIR 28 bone seeker 8
cancer mortality, 1976-2070 42 effects of carcinogens or ionizing
radiation 42 cancer mortality and radiation dose,
correlation 66 chemical radioprotection 97 - 132
effect of radiation type 119 high LET, neutrons 119, 120 low LET, X-rays or y-rays 119
gastrointestinal death 104, 119 hematopoietic radiation death 104,
105, 119 hematopoietic radiation syndrome
104,105, 119 in mammals 97-123, 126-132 in man 97,101,102,123-126,131,
132 Chernobyl accident 75, 79, 80, 82,
90-92 RBM K-1 000, characteristics 80
Chernobyl accident, medical measures 79, 80, 82, 90-92 blood transfusion 91,92
bone marrow transplantation 88, 91
firemen members of the general population 90
hospital wards under aseptic conditions 91
patients classified into four groups by degree of injury 90
prevention of endogeneous infections, antibiotics 91
prophylaxis and treatment of infections 87,91
substitution of platelets and erythrocytes 87,91,92
workers at the plant 90 chromosomal diseases 47,48, 113 collective dose equivalents 29 combined injuries: radiation effects,
burns and/or wounds 117 animal mortality studies 117 benefit of radioprotective agents
117 burn 117-119 injuries in animals by skin
wounds, superficial burns, and whole-body irradiation 117-119
irradiation 117 - 119 skin wound 117-119 whole-body irradiation and surgi-
cal operations 119 committed dose equivalents 36, 50 core melting 75, 78, 79 cosmic radiation 2, 9
absorbed dose rate 9 dependency on geographic latitude
and sun activity 9 dose equivalent rate 9 energy spectrum 2 exposure during flights at high altitu
des 9 exposure during space travel 9, 10 increase with height above sea level
9 neutron flux density 2 primary 2,9 secondary 2 solar flares 2, 9 solar galactic radiation 9 total dose equivalent 2 van Allen radiation belts 9
critical organ 34 cystamine tablets in the ABC selfpro
tection kit 124
diagnosis of radiation injuries 27, 86, 87
direct and indirect radiation effects, in-fluences of radioprotectors 121, 127
dose equivalents 30, 33, 36, 50 dose equivalent commitment 35,36 dose equivalent limit (L) 30-33,35,
36 external exposure 32
deep dose equivalent index 32 internal exposure 32 total stochastic risk for nonuniform
whole body exposure, weighting factors 32, 36
uniform whole body exposure 32 dose fractionation 45 dose limitations 28, 29 dose limits proposed by ICRP 26,29,
43, 73 dose modification factor 98, 107 dose protraction 45 dose reduction factors (DRFJ 98,99,
103, 106, 120 comparison of radioprotective
agents 98 definition 98 dose-effect relationship, criterion
death or survival 98, 108, 109 gastrointestinal injury 119
neutrons 119, 120 relative efficacy of radioprotective
chemicals 98 survival curves, rates 98, 102, 103
dose-response relationships 26, 29, 43-45 consequences to risk estimations 43,
45 hormesis at low doses 44 linear dose relationship 43, 45 linear quadratic relationship 44, 47,
79 linear relationships without thresh
old 43,45 quadratic relationship 44 relationship with exponent smaller
than 1 45 threshold for stochastic effects 44
DRF 98,99, 103, 104
effective dose equivalent 31-33,35, 36
effects from low dose exposures 43 embryotoxicity of radioprotective
agents 114
146
emergency measures for nuclear power plants 80- 82 early phase 81, 85
dose equivalent levels 81 intermediate phase 81, 85 levels of alarm 80
emergency alarm 81 emergency warning 80 special alarm - water 81
nuclear risk potential 80 permissible radioactivity levels in
food 80 phases of a serious accident 81, 85 radioactivity in the environment 81 recovery phase 81
emergency station, organizational structure 88 contamination measurements 88 medical examination 88 registration interview 88
energy production, radiation exposure coal-fired power plants 19
emissions of radioactive substances 19,20
radioactive substances in the fly ash 19
radioactivity concentration in coal 19
oil, natural gas, and geothermic energy 20
epidemiology of occupational radiation hazards 46, 48, 62 analytical methods 62 case control studies 62 cohort studies 62 comparison groups 62 confounding factors 63
age, sex, ethnic group 63 calendar year 63 distribution of exposure doses 63 effect doses within the range of na-
tural radiation exposure 63 temporal pattern of incidence and
mortality 63 nested studies 62
estimation of risks 31 comparisons of radiation exposure
with other occupational risks 31, 41,42,61 fatal malignancy 32 mean annual mortality 31,41
exposure outdoors 3, 4, 12 annual effective dose equivalent 3
fission products 76- 78 fallout 75, 76 from a nuclear weapon explosion
75, 76 in the core of a reactor 76
genetic significant dose 50 German reactor safety study 77,83
healthy worker effect 62,68, 71 high thorium or uranium concentration
in the soil, regions 3, 7
Hiroshima and Nagasaki 46,47,61, 64, 92 combined injuries 92 effects of revision of the dosimetry
47 cancer induction 47 chromosome aberrations 47 development of the brain 47
follow-up studies 47 animal experiments 47
hereditary effects 45,47,48 survivors 46,47,61,64,92
hospitals for treatment of very serious forms of radiation injury 89
human epidemiological studies 46,61, 64, 73
ICRP risk factors 42,45-48, 73 incorporation of radioactive substan
ces 32,35 19 interactions between chemicals and
radiation 98 antagonism "radioprotection" 98 enhancement "sensitization" 98
internal irradiation by radionuclides 3-8
International Commission on Radiological Protection (ICRP) 28,61 committees 28 publications, statements and recom
mendations 28, 84 irregular diseases 47, 48 irregularly inherited diseases 47, 48
LDso (radiation dose for 50% lethality) 98-100
limits of dose equivalents for work 30, 32,33 annual limits for workers 33 category A and category B 33 special working conditions 33
accidents 33 extraordinary events 33 medical applications 33 pregnant women 33
workers under 18 years of age 33 limits of radiation exposure 30,61,71
comparing risk with that for other occupations 31, 41, 42, 61
epidemiologic studies 46,61,64 linked diseases 47, 48 lung cancer in miners 17,49,63
Schneeberg disease 63 lung cancer risk in mines 17,49,63,64 lung cancer risk for population 17,18,
63-65
medical problems after a reactor accident 87 - 89 decontamination 87 first-aid measures 87 help of regional radiation protection
centers 87 medical care for workers 87
diagnostic procedures 89 outpatient care 89
Subject Index
therapeutical measures 87 miners, radiation carcinogenesis 17,
49,63,64 mutagenicity, radiation-induced 47,48
linear relationships without thresholds 43,45,47,79
mutscheller dose 25
natural external radiation exposure 2 natural internal radiation exposure
3-8 non stochastic effects 28, 36, 84 non stochastic somatic effects 28,31,84 nonuniform whole body exposure,
weighting factors for tissues 32, 36 nuclear bomb explosions, combined in
juries 75, 92-94 additional trauma 93 animal experiments 92 combination of burns with radiation
doses 92 combined injuries, trauma, infec
tions, wound, burns, severe exhaustion, or stress 92
effect of open skin wounds 93 medical care 92 pathology and management of
injuries 92 recommendations caring for patients
with combined injuries: wound excision 93 surgery 94 tolerance to drugs 94
nuclear industry, radiation carcinogenesis 49,67 all workers summed up 73
myeloma in Hanford and Sellafield, significant trend 73
epidemiologic methods 67 Hanford study 49, 67
all malignant tumors 68 brain tumors 68, 70 carcinoma of the pancreas 68, 70 comparison with natural radiation
exposure 69 doubling doses and the latency of
the different tumors 68 frequency of leukemia and cancer
67 higher radiosensitivity of the work
er over 40 68 lung cancer 68 methods used in the analysis of the
Hanford data 69 myeloma 68, 70
Oak Ridge National Laboratory study 70 carcinoma of prostate 70 external radiation exposure 70 Hodgkin's disease 70 incorporation of radioactive sub-
stances 70 leukemia 70 mortality compared with popula
tion of the USA 70 myeloma 70
Subject Index
Sellafield study 70-72 cancers of liver, gallbladder, and
lung 71 comparison of causes of death
among Sellafield workers with those in the population 71
Hodgkin's disease 71 leukemia 71 mortality from bronchitis 71 myeloma 71
shipyard workers study 72 building and overhauling nuclear
submarines 72 leukemia deaths 72
UKAEA study, Atomic Energy Authorities 72 bladder cancer 72 brain tumor 72 cancer of the prostate 72 death among the employees in
comparison with the national cancer mortality 72
lung cancer 72 stomach cancer 72
occupational exposure, dose limitations 26, 28, 43, 73
occupational exposure, dose equivalent limits 30,32,33,50,61 linear energy transfer (LET) 30 quality factor 30
occupational exposure to radiation 26, 61 causes of death up until 1959 26,61
occupational exposures, measurement and statistical statements 48-53 control measurements of laboratory
air 52 cost-benefit analyses 29, 50 dose-controlled workers and plants
29,49,51 nuclear plants 51, 52 workplaces 29,49,51
exposures of fingers 52 external doses, results for incorpora
tion 50 body counters 50 urine samples 50, 51
inhalation and incorporation of a-emitters 49 persons handling radon therapeu
tically 49 radium dial painters 49, 67 studies on workers in uranium
plants 49 workers in the Hanford plutomi
um plants 49, 67 results of exposure control 50, 52
industrial radiography 52 industry 52 medical research 52 nuclear medical practice 52 nuclear plants 51, 52 radioimmunoassay techniques 52 radiopharmaceutical laboratories
52
statistical studies comparing exposed and nonexposed workers 48, 62 carcinogenic effects 48, 61, 62 determining the rates of chromo-
some aberration 49 frequency of dermatitis and skin
cancer 49,61,65 workers exposed during working
Jives 46,48 occupational exposures, quantification
of risks 41-48,61-73 comparison with other industries
31,41,42,61 loss of working hours 42 manifestation of malignancy 41,
42,61 ICRP concept, index of harm 41,42
admissibility for low dose range 42
occupational risks of exposures 26, 28 ALARA 28-30,41 figures for limits 28 (CRP system of dose limitation 29 principles and practices 28 risks of harm within limits 28
oxygen enhancement ration (OER) 121
210Pb 8 phosphate ores, radiation exposure 18
by-product gypsum 19 phosphate fertilizers 18
4OK, 226Ra, 2J2Th concentrations 18,19
phosphoric acid 19 21OpO 8 pulmonary radiation syndrome 110
126Ra, radioactive decay properties 13 Ra and Th in building materials 15 radiation accidents, medical aspects
75-94 radioactivity, release 76
barriers to prevent release of fission products 77
reactor accidents 75 core melting 75 nuclear weapons testing 75 radioactive substances from nucle-
ar bomb explosions released and deposited as ,,fallout" 75, 76, 79
radioactive substances from reactor accidents released and deposited as "fallout" 75, 76, 79
radiation carcinogenesis 41-48, 61-78 radiation, directly ionizing 2 radiation dose for 50% lethality =
LDso 98-100 radiation dose and rate of mutations
25 doubling dose 25 proportionality 25
radiation doses 1 natural range 1 technologically modified 1, 8-22
unmodified 1-8,21,22 external 2, 3 internal 2-8
radiation effects 26,27,86, 87 nonstochastic 26-28
threshold values 26 thresholds 28, 31, 84
147
radiation effects after whole-body exposure 27, 86, 104 cardiovascular manifestations 87,
104 central nervous system death 104 diarrhea 104 gastrointestinal death 104, 119 gastrointestinal symptoms 104, 119 hematopoietic death, syndrom 104,
119 radiation exposure, natural 1-24
technologically modified 8-22 by building materials 9 by coal and burning 8 by flights at high altitudes 9
radiation exposure, non-natural 1 radiation, indirectly ionizing 2 radiation injury after total body expo-
sure, radiation syndrome 26, 85-89 blood lymphocyte count decreases
87 bone marrow failure 87 damage of the intestinal mucosa 87 diarrhea 87 disturbances in hemopoiesis in the
damaged bone marrow 85 effects on the central nervous system
and cardiovascular system 87, 104 relationship between radiation dose
and early symptoms 87 symptom-free latent time 86
radiation protection 29,50, 51, 97 -132 ALARA 28-30,41 cost-benefit analysis 29, 50
gross benefit 29 net benefit 29, 84
exposure control 29, 49 external and internal exposures 29
diagnostic radiology 30 nuclear medicine 30 radiotherapy 30
facilities 50 international and national commit
tees 30 operational problems 51 optimization 29, 50
radiation protection of reactor staff and general popUlation 84 decontamination of ground, roads,
and buildings 85 early phase 81, 85 individual doses, collective doses 85 intermediate phase 85 intervention levels in emergency
plans 85 phases of a serious accident 81, 85 recommendations of the (CRP 28,84 recovery phase 81, 85 variety of accident scenarios 84
148
radiation syndrome 26,85,87,89,90, 92 bone marrow transplantation 88, 91 substitution treatment with granulo-
cytes and thrombocytes 87,91 symptoms and prognoses 26, 27 therapy with antibiotic drugs 87, 91
radiation victims 26, 61 radioactive iodine released during reac
tor accident 82 accumulation in the thyroid gland
82 distribution of iodide tablets after ac-
cident 82 incorporation 82 recommended dose 82 risk of induction of hyperthyroidism
and thyrotoxicosis 83 radioactivity, release in an accident 75,
76,79 factors affecting danger to people
77 contamination of the body
surface 77 external body irradiation 77 internal radiation exposure 77
radiodermatitis 26, 28, 61 radiologists, radiation carcinogenesis
65,66 cancer of pancreas 47,65,66 cancer risk in radiologic technolo-
gists related to radiation dose 66 leukemia 65, 66 mortality from skin cancer 49,61,66 mortality patterns 65 radiologists compared with ophthal
mologists 66 radionuclide 32,36-41,52 radionuclides, annual limits for intake
(ALI) 32, 36-41, 52 ALARA 28-30,41 classes D, Wand Y 37 compartmental models for respirato-
ry system and gastrointestinal tract 37
derived air concentrations (DAC) 37-41
handling of tritium targets 52 nonstochastic effects 36 radioactive clouds of gas 37 retention of compounds in the
pulmonary region 37 stochastic effects 36 tritiated thymidine 52 use of short-lived radionuclides 53 weighting factors for tissues 32, 36
radionuclides, cosmogenic 3 contribution to natural exposure 5
annual absorbed doses 5 annual body doses through inter
nal radiation 5 annual intake 6
radionuclides, free limits of handling 41
radionuclides, groups of radiotoxicity (GRD 38-41
radionuclides in building materials 10 activity concentration 10 dose rates from indoor terrestrial
y-irradiation 10- 12 exposure indoors 10, 11 maximum permissible concentra
tions 10 mean dose to the gonads 12
radionuclides, internal irradiation 3-8 radionuclides, limits for incorporation
(ingestion and inhalation) 34 ICRP scheme for determination of
dose equivalent 34, 35 deposition 35, 36 intake 35, 36 metabolic routes 35 uptake 35, 36
passage through organism 34 concept of transportability 34
radionuclides, naturally occurring in industrial products 21 enhanced natural sources of radia
tion 1,22 annual effective dose equivalent
1,22 natural sources of radiation in areas
of normal backround 22 annual effective dose equivalent
22 unmodified 1,21
annual effective dose equivalent 21
averaged worldwide 21, 22 radionuclides, primordial 5
contribution to internal natural radiation exposure 5 annual absorbed doses 6-8 concentration in adults 6-8
radionuclides, unsealed handling in nuclear medicine 34 contaminations 34 external exposures 34 incorporation 34
radioprotective agents 99-101 against late radiation injury (late
effects) 115 cataract 116 damage in skin, muscle, and vas
cular tissue 117 glomerulosclerosis, nephrosclero
sis 117 tumors, leukemia, and lym
phomas 115,116 biochemical mechanisms of action
130 biochemical shock 131 combination of radioprotectors
132 duration of action 132 effect of enzymes 132 efficacy of cyclic mononucleo-
tides 132 inhibitory effect on DNA synthe
sis 131 noncyclic mononucleotides 132
Subject Index
specific receptors on plasma membrane, effect of receptor blokkers 131
chromosome damage 114 clinical applications 123
against radiation sickness 123, 125
against side-effects of radiotherapy 123-125
curative effects 124 effects on lymphocyte counts, leu
kocyte counts, platelet counts and aberration yields 125, 126
following radiotherapy 123-125 pharmacokinetic properties, toxici-
ty, maximum tolerated doses 125 prophylactic effects 124 radiation sickness 123, 125 radiotherapy 123, 124 side-effects in patients after radio-
protector infusion 125, 126 side-effects of radiotherapy 123,
125 dose that cause 50% lethality 100 dose-effect curves 98, 108, 109 effect against hematopoietic death,
gastrointestinal death and CNS death 105
effects in organs and tissues 105 digestive tract: crypt cells, small
intestine, and colon 109, 110 effect on cell of the bone marrow
and peripheral blood 107 gonads: testes and ovaries 111,
112 hematopoietic organs and blood
106 kidney 111 liver 111 lymphatic system and immune
responses 108 nervous system 113 protection factors 99, 108 protective effect 108 protective factors for skin and
bone marrow 105 respiratory tract 110 salivary gland 111 skin: erythema, edema, hair loss,
moist desquamation, and crusting 108
thyroid gland 111 radioprotective agents effect of route
of administration, solvent and pH range 101
oral use of radioprotective agents 102, 103
radioprotective effect 101, 103, 108
effect on radiation-induced developmental anomalies 114 congenital anomalies 115 fetal absorption 115 fetal weight 115 intrauterine death 115 neonatal and postnatal deaths 115
Subject Index
postnatal weight changes 115 suppression of brain 115 teratogenicity 115 testicular damage 115
effect of time 102 embryotoxicity 114 genetic studies 113
in vitro experiments on human lymphocytes 113
in vivo experiment in mammals 113
in man 97, 101, 102, 123-126 list of chemical compounds and
abbreviations 100, 107 mechanism of action (see also bio
chemical-, pharmacodynamic-, and physiochemical mechanisms) 126 biogenic amines 126 nucleotides 126 sulfur-containing compounds
126 vitamins 126
pharmacodynamic mechanisms of action 128-130 anoxia of tissues 129 body temperature 130 decrease in oxygen consumption,
respiration, and rectal temperature 129
effect of vasoconstrictive properties 129
oxygen tension 129 prime determination: oxygen and
temperature 128, 130 temperature reduction 130 vasodilation 129
physiochemical mechanisms of action 126- 128 electron donor mechanism 127 formation of mixed disulfides with
plasma proteins 127 interaction with radiosensitive
structures of the cell 128 reaction with radiolysis products
of water 126 SH and SS groups 127 sulfhydryl groups bound to pro
teins 127 superoxide dismutase (SOD) 127
survival rate 98, 102, 103, 106 delayed radioprotective effect 103
timing of administration and radiation exposure 102 fractionated irradiation 103 oral use 102, 103 prolonged exposure 102 single-dose irradiation 103
toxicity 99, 101 effective dose 99 in terms of drug dose per unit
body surface area and per unit body weight 101
protection factor (PF) 99 protective index (PI) 99 therapeutic index (TI) 101
tumor therapy 121-126 ascites tumors 122 cell carcinoma 12 Crocker sarcoma 121 Ehrlich carcinoma 121 in leukemia cells 123 solid tumors 122, 123 Walker rat carcinoma 121, 122
radioprotective chemicals occurring naturally in mammals 130
radioprotective compounds (see also radioprotective agents) 104 survival rate 98, 102, 103, 106
radioprotective drugs (see also radio-protective agents) 97,99, 106
radioprotective effect and hyperthermia 130
radioprotectors (see also radioprotective agents) 102, 110 drug combination 110, 112
radioresistance 119, 121, 122, 127, 130-132 human cancer cells 101, 123-126,
131 studies in human medicine 101,
123-126, 132 radium dial workers, radiation carcino
genesis 49, 67 epidemiologic studies 67 external radiation exposure 67 incorporated radium 67 increase in number of breast cancer
67 latency time 67 malignancy induced 67
radon 12, 14- 17, 20, 63, 64 building materials, exhalation rate
14-17 concentration 15 concentrations of radon and decay
products in- and outdoors 16 equilibrium factor in room air 17, 18 exhalation rate 15 in natural gas used in households 20 lung cancer risk for population 17,
18 mean resulting lung dose 17,18 potential a-energy 15
concentration of mixture of decay products 14, 15
power plant using geothermic energy release 20
radiation exposure by inhalation 12-18,20,63
room air exchange rate (ventilation rate) 16, 17
with the short-lived radon daughters 15-17,63,64
working level 14 radon daughter exposure and resultant
lung cancer 64 cigarette smoking 65 latent period 64
RBE factors 45,47, 119 exposures to y-rays 47 exposures to neutrons 47
149
reactor accident, contamination and decontamination of body surface 83 contamination of skin and clothing
83 decontamination process 83, 87 levels for decontamination of skin 84 measurements looking for contami-
nation 83 reactor accident, evacuation of the po
pulation 81 reactor accident, prophylaxis of the thy
roid gland 82, 83 reactor accidents, medical aspects
75-94 risk studies 77 - 80
reactor safety studies 77,83 German Reactor Safety Study 78 WASH 1400, Rasmussen 77
reference man 34, 36 source organs 36 target organs 36 weight of organs 36
relative biologic effectiveness (RBE) 45,47,119
release of radioactivity 75, 76, 79 repair mechanisms 47,49, 114
and immunologic reactions 47,49, 114
resistance 119, 122 risk estimates, risk factors 42, 45-48,
73,79 absolute risk model 46 average hereditary risk factor 47, 48
doubling dose 48 cancer induction 45, 79 cancer mortality risk estimates 46 cataracts 45 DS86 47 epidemiologic investigations 46,61,62
patients given radiotherapy 46 persons exposed during working
life 46,48,61 hereditary effects 45,47,48 incidence of harm from exposure
during pregnancy 45,47,48 incidence of leukemia 47,65 index of harm 42 linear quadratic relationship 44, 47 relative risk model 46 TD 65 47
risk factor 42, 45 -48, 73, 79 acute death 79 late injuries: cancer and genetic
damage 45, 79 proportional dose-effect relation
ship 43, 45, 79 suggested by ICRP 42,45-48,73,79
22°Rn inhalation 13 222Rn inhalation 13
scavenger effect of radioprotectors 126, 127
scavenging mechanisms 113, 126, 127 sex-linked diseases 43, 47 short-lived decay products, potential
-energy 15
150
skin cancer after exposure 49, 61
smokers, daily intake 8 SMR 62,65,68, 70, 71 solar flares 2, 9 spleen colony technique 106 standardized mortality ration (SMR)
62,65,68,70 stochastic effects 31, 35, 36, 84 symptoms after acute whole body irra
diation 27, 86, 87 therapeutic and prognostic conclu
sions 27, 86
terrestrial radiation 2, 10- 12 areas with increased 3, 7 dose rates 3, 4 exposure indoors 11, 12
outdoor terrestrial y-irradiation 3, 4 sources 3
thoron 14 building materials, exhalation rate
14-17 concentration 15 concentrations of thoron and decay
products in- and outdoors 16 equilibrium factor in room air 17,
18 exhalation rate 15 lung cancer risk for population 17,
18,63 mean resulting lung dose 17, 18 potential a-energy 15 potential a-energy concentration of
mixture of decay products 14, 15
Subject Index
radiation exposure by inhalation 7, 12-18,20,63
room air exchange rate (ventilation rate) 16,17
working level 14 228Th, radioactive decay properties 14 Three Mile Island accident 79-81 thyroid gland carcinoma from incorpo-
ration of radioactive iodine 82 tolerance dose 26
UNSCEAR 28
workers in uranium mines 49, 63-65 working conditions, classification A
33, 50 classification B 33
X-ray hands 25, 61
Medical Radiology Diagnostic Imaging and Radiation Oncology
Edited by: L. W. Brady, Philadelphia; M. W. Donner Baltimore; H.-P. Heilmann, Hamburg; F. Heuck, Stuttgart
Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong Kong
J.H.Anderson, Johns Hopkins University, Baltimore, MD (Ed.)
Innovations in Diagnostic Radiology With contributions by numerous experts
Foreword by M. W. Donner, W. R. Brody, F. Heuck
1989. XIII, 212 pp. 144 figs., some in colour. Hardcover ISBN 3-540-19093-7
The current status and future applications of various diagnostic imaging procedures are discussed in this volume. The main focus is on research and development, in particular the potential they hold for further development and clinical application in various specialties. Those concerned with the academic growth of radiology as a discipline, such as basic scientists, young clinicians in training, and chairmen responsible for department planning, will be especially interested in the trends presented here. The subject matter includes magnetic resonance imaging, interventional radiology, ultrasound, image analysis and management, positron emission tomography, and research training programs. The volume emphasizes the multidisciplinary direction of medical imaging; both basic scientists and clinicians in a wide variety of medical research areas should be aware of this tendency and the opportunities which will be available in the future.
R. R. Dobelbower, Jr., Medical College of Ohio, Toledo (Ed.)
Gastrointestinal Cancer Radiation Therapy
Foreword by L. W. Brady and H.-P. Heilmann
1989. XIV, 298 pp. 81 figs. 77 tabs. Hardcover ISBN 3-540-50505-9
The intricate role of radiation therapy in the management ofGI cancer is comprehensively reviewed in this timely volume. It offers unique coverage of the entire gastrointestinal tract, from the esophagus to the anus. Although the work focuses clearly on the radiotherapeutic management of tumors of the GI tract, reviews of anatomy, epidemiology, and other pertinent topics are given. The volume is generally organized by disease site, but extensive special sections amplify important aspects related to GI cancer. These include the radiographic evaluation ofGI malignancy and tumor markers, an up-to-date review of chemotherapeutic treatment of gut cancers, and patient follow-up. Edited by an internationally known leader in the field of radiotherapy, this volume represents a compilation of years of research and experience utilizing today's technology and state-of-the-art techniques.
Medical Radio ogy Diagnostic Imaging and Radiation Oncology
Edited by: L. W.Brady, Philadelphia; M. W. Donner, Baltimore; H.-P. Heilmann, Hamburg; F. Huck. Stuttgart
Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong Kong
G.E.Laramore, University of Washington (Ed.)
Radiation Therapy of Head and Neck Cancer Foreword by L. w. Brady and H.-P. Heilmann
1989. XII, 237 pp. 123 figs. Hardcover ISBN 3-540-19360-X
This volume considers the treatment of head and neck cancer from the point of view of the radiation oncologist. The epidemiology of head and neck cancer, evaluation of the patient, and basic treatment issues are discussed and the separate chapters are devoted to specific head and neck sites. The book provides a valuable summary of treatment approaches and results representing the best standard of care in the United States, Canada, and Europe. It offers a consensus approach and does not set forth the particular attitudes of any single institution. A comprehensive survey of the relevant literature is presented at the end of each chapter. Material is treated in such a way as to be relevant both to the practicing clinician and the resident in training.
H.R. Withers, University of California at Los Angeles; L. J. Peters, University of Texas (Eds.)
Innovations in Radiation Oncology With contributions by numerous experts
Foreword by L. W. Brady and H.-P. Heilmann
1987. XVII, 329 pp. III figs. Hardcover ISBN 3-540-17818-X
Contents: General Aspects. - Conservation Therapy. - Extended Field Therapy. - Restricted Field Therapy. - New Imaging Technologies and Radiotherapy. - Modified Fractionation. - Drugs and Radiation. -Neutrons. - Adjunctive Therapies. - Subject Index.
C. W. Scarantino, Wake Forest University, Winston-Salem (Ed.)
Lung Cancer Diagnostic Procedures and Therapeutic Management with Special Reference to Radiotherapy
With contributions by numerous experts
1985. XI, 173 pp. 42 figs. Hardcover ISBN 3-540-13176-0
This up-to-date reference book covers a broad range of topics regarding lung cancer. There is an extensive review of recent epidemiological and early detection studies, as well as of current histological observations of the tumor heterogeneity of lung cancer. It presents an up-to-date examination of the latest clinical developments in diagnosis and treatment as well as results of clinical trials employing irradiation chemotherapy and surgery.