Pioneering Solutions in Fluorochemicals
Ron Epstein
Sales Director
History
• Halocarbon was founded in 1950 to make inert lubricants.
• First commercial producer of CTFE inert lubricants.
• First and largest producer of TFA, TFE, TFAC and TFAA.
• First commercial quantities of CFC substitute HFC-134a and HFC-32.
• First U.S. producer of fluorinated anesthetics.
Halocarbon Today
Three product lines based on our fluorochemicals experience
• Inert lubricants
• Inhalation anesthetics
• Fluorochemicals
Staff
• 150 employees (20 technical staff)
Manufacturing
• Extensive complex in South Carolina USA
• Grams to tons capability in technical development area
• Hundreds of tons capability in production area
Halocarbon Complex
Halocarbon Quality
0
100
200
300
400
500
600
700
0 5 10 15 20 25 30 35 40 45 50 55
•TFA >99.9%
•TFE >99.98%
•ETFA >99.9%
•TFAA >99.5%
Our Expertise
High quality grams to tons production at competitive prices
• Halogenation – radical, exchange, etc.
• Oxidation/reduction
• Amination/amidation
• Esterification/alcoholysis
• Alkylation
Benefits of Fluorination
• Pharmaceuticals
• Anesthetics
• Biomedical uses
• Agricultural chemicals
• Fluoroplastics
• Fluoroelastomers
• Chlorofluoropolymers
• Membranes
Basic Building Blocks
• TFAC trifluoroacetyl chloride
• CDFAC chlorodifluoroacetyl chloride
• DFA difluoroacetic acid
• HFA hexafluoroacetone
• ETFAA ethyl trifluoroacetoacetate
F3C Cl
O
F3C OH
O
F3C OH
F3C OR
OF3CO
OF3C
O
Trifluoroacetyl chlorideTrifluoroacetic anhydride
Trifluoroethanol
Trifluoroacetic acid
R = Et, Me, i-Pr
Alkyl trifluoroacetates
F3C OCHF2
Cl
Isoflurane
TFAC and Derivatives
F3C Cl
OF3C NHR F3C NHR
O
F3C H
RO OH
Trifluoroacetyl chlorideTrifluoroethyl amines
R = H, Me
Trifluoroacetaldehyde hemiacetal
R = Me, Et
R = H, Me
Trifluoroacetamides
TFAC and Derivatives
HFA and Derivatives
F3C CF3
O
F3C CF3
OH
F3C CF3
OCH2F
CF3
CF3OH
CF3
CF3
OH
F3C
CF3
OH
Hexafluoroacetone Hexafluoroisopropanol Sevoflurane
Norbornene HFIP
Vinyl HFIP
Allyl hexafluoroisopropanol
CF3
F3C OH
2-Phenyl HFIP
(via Grignard reactions)
Global Business
• Distributors – Europe, Middle East, Asia
• Growth
• 60% of sales
• Focus– Development investment
Recap
• Pioneer in fluorochemicals
• Grams to tons capabilities
• Focus on custom synthesis
• Global distribution
• Working with major pharma companies
• “What Can We Make For You?”
For more information,please visit Halocarbon at booth
812
Ron Epstein - Sales [email protected]
201-262-8899 Ex. 36
www.halocarbon.com