P16081: SYSTEMIC CIRCULATION MODELSUBSYSTEM DESIGN REVIEW
John RayFabian PerezRobert Kelley
Mallory LennonJacob Zaremski
Our goals for this review Updates from Phase II Review (10 minutes)
CAD Schematic Analysis Subsystem Analysis (25 minutes)
Risk Analysis (5 minutes) Bill of Materials (BoM) (5 minutes) Project Plans (5 minutes)
Agenda
Goals
1. Introduce progress in engineering analysis
2. Address budget concerns
3. Demonstrate efforts to design for modification
4. Receive feedback
5. Create action plan
Finalized Objective
Our goal is to deliver a functioning physical model of systemic circulation which, when
used in conjunction with P16080’s heart pump, will be used as a teaching tool, allowing
students to validate mathematical models of the circulatory system from Chapter 5 of
“Quantitative Human Physiology” An Introduction by Joseph Feher. The model will
ultimately enhance students' understanding of the circulatory system by enabling
them to analyze the circulatory system under normal, exercise, and pathological conditions
through the measurement of pressure and flow.
Updated Use Case
ER Metrics of Quality (1 of 3)
ER Metrics of Quality (2 of 3)
ER Metrics of Quality (3 of 3)
ER mapping to F.D. (1 of 2)
ER mapping to F.D. (2 of 2)
Functional Decomposition
Morph Chart (1 of 3)
Morph Chart (2 of 3)
Morph Chart (3 of 3)
Undecided Concepts
Pressure• PASCO versus Honeywell
• LabVIEW versus DataStudio
Resistance• External Clamp vs. Valve
Updated System Architecture
CAD Schematic
Main Components
Barb tube fitting: cheapest, easiest
connection
Pressure release value: easy release valve
Drill and screw into acrylic
Ball pump: cheapest,
easiest way to add air pressure
Pressure tap into tubing
Pressure, PA
Pressure, PC Pressure, PV v
P16081 Pump
Arterial Compliance,
CA
VenousCompliance,
CV
Flow
Resistance
1
2
345
LabVIEW
6
7 8 9
Subsystems Agenda
1 & 5 - Pressure
2 & 4 - Compliance
3 - Resistance
6 - Labview
7, 8 & 9 - Consult with P16080
Pressure Sensor Analysis1. Flow Diagram
2. PASCO Sensors
3. Honeywell Sensors
4. Bill of Materials
5. Test Plan
6. Risks
Pressure Flow Diagram
Analog Pressure Signal
Digital Pressure Signal
DAQ
Amplifier Board
ComputerLabView Program
AC Power
Energy
Information
Pressure vs. Time Graph
PASCO Sensors
Will need more than one computer for real time system analysis
• LabView for heart, DataStudio for circulatory pressures
• LabView needed for automatic resistance control
Pros Cons
Already Owned No integration with LabView
Differential Pressure Capabilities
Special Pressure Taps Needed
User Friendly
http://www.pasco.com/file_downloads/product_manuals/PASPORT-Dual-Pressure-Sensor-Manual-PS-2181.pdf
Maximum Sampling Rate 1000 Hz
Absolute Pressure Range 0-1500 mmHg
Differential Pressure Range -750-750 mmHg
Resolution 0.075 mmHg at 10 Hz
Repeatability 7.5 mmHg
Tubing (Type) Polyurethane
Tubing Size (Diameter) 3.2 mm
Tubing Length 2.4 m
InterfaceData Studio (New one coming soon?)
Source:PasPort Instruction Sheet (012-09969A)
Honeywell Sensors
Only one computer program needed for both heart and circulatory
• DAQ is already provided, but would need to build the circuit board/LabView Program
http://www.mouser.com/ProductDetail/Honeywell/HSCMRNT005PGAA5/?qs=%2fha2pyFaduhkciXVz6btFHLY3u79xkDhknp39AuPvmffYIGgrGx0aQ%3d%3d
Pros Cons
Integration With LabView
More Expensive than PASCO
Accuracy Will need a Sensor Board/DAQ
Liquid Friendly
TruStability Board Mount Pressure Sensors: HSC Series (HSCMRNT005PGAA5)
Operating Gage Pressure Range 0-258 mmHg
Output Type Analog
Pressure Type Gauge
Operating Supply Voltage 5 V
Operating Temperature -40-85 C
Operating Supply Current 20 mA
Accuracy 0.25%
Liquid Media Capable? Yes
Source:
HSCMRNT005PGAA5 Datasheet (Mouser.com)
Honeywell SensorsDimensions
http://www.mouser.com/ProductDetail/Honeywell/HSCMRNT005PGAA5/?qs=%2fha2pyFaduhkciXVz6btFHLY3u79xkDhknp39AuPvmffYIGgrGx0aQ%3d%3d
Pressure BOMComponent
IDComponen
tSupplier Supplier ID Quanitity/Dimensions Price/Unit Total
CostNotes
P1 Honeywell Board Mount Pressure Sensor
Mouser Electronic
HSCMRNT005PGAA5 2 $45.78 $91.56 May only need 1 (48.85)
P2 PASCO Sensor
PASCO PS-2181 2 Free - Already Owned
P3 Pressure Taps
PASCO ME-2224 6 $16.00 $96.00 Comes as a set of 6
Might be able to borrow for free (Rep mentioned it)
Pressure Risks
5 Technical Not being able to generate required values
6 Technical Seal on the pressure tap leaks
7 Technical Not being able to calibrate within time constraints
9 Resource System components will be expensive
11 SafetyElectricity and water combination can cause
dangerous conditions
Owner: Jack
PRESSURE TEST PLAN1.Prove Sensor Functionality
a. Flow through a pipe with decreased diameter in the center
b. Pressure taps at two points
c. Measure the pressure drop
2.Calibration of the Sensors
a. Obtain a full tank of known pressure
b. Measure the pressure and correct accordingly
Subsystem - Compliance Tank1. Flow Diagram
a. Energy, Material, and Information I/O
b. Interfaces
2. Cylinder or rectangular prism?
a. Pros and cons
b. Feasibility
3. Bill of Materials (Draft)
4. Subsystem Risks
5. Preliminary Ideas for Testing Plans
Pressure
Flow
AC Power
Air Height Compliance
Pressure TransducerLabVIEW
Pressure vs. Time
Flow
Pressure
Forced Air
Energy
Material
Information
Cylindrical Tanks
ProsFewer pieces
Less interfaces to seal
ConsPrice limits diameter
Interfacing with tubing and pressure taps
Rectangular Tanks
ProsFlat surfaces easier to machine and
interface
ConsMore pieces that need to be machined
and sealed
Cylindrical Arterial Compliance Tank
2 3 4 5 6 7 8 9 10 11 120
0.5
1
1.5
2
2.5
3
3.5
4
4.5
5 Polycarbonate 5.75ID [in]
Acrylic 5ID [in]
Height (inches)
Co
mp
lia
nc
e (
mL
/mm
Hg
)
Cylindrical Venous Compliance Tank
0 5 10 15 20 250
5
10
15
20
25
30
35Acrylic 9.75ID [in]
Polycarbonate 5.75ID [in]
Height (inches)
Co
mp
lia
nc
e (
mL
/mm
Hg
)
Rectangular Arterial Compliance Tank
2 4 6 8 10 12 14 160
1
2
3
4
5
6
7
8
9
4x4x12 [in]
4x8x16 [in] (Donovan)
Height (Inches)
Co
mp
lia
nc
e (
mL
/mm
Hg
)
Rectangular Venous Compliance Tank
2 4 6 8 10 12 14 160
5
10
15
20
25
30
35
40
12x12x16 [in]12x8x16 [in] (Donovan)
Height (inches)
Co
mp
lian
ce
(m
L/m
mH
g)
Technical Risks - Compliance Tank
Resource & Safety Risks - Compliance Tank
Compliance BOM - Cylindrical
Compliance BOM - Rectangular
• 6-sided tank would be around $200
Compliance - Preliminary Testing Plans
1.Air tight seal
a. pressurize, use soap, and look for bubbles
2.Generate chart to allow students to know which height
corresponds to a desired condition - scale on box
3.Excel spreadsheet for liquid height and corresponding
compliance values
Resistance Agenda1. Flow Diagram
2. Valve and Resistance Analysis
3. Bill of Material and Alternative Bill of Materials
4. Risks
5. Test Plans
Resistance Flow
Valve and Resistance AnalysisResistance can be modeled after Ohm’s Law in that: R=ΔP/F where ΔP is
the height difference and F is the mean flow rate.
[http://circ.ahajournals.org/content/89/2/893.full.pdf]
Valve and Resistance ContinuedFor Valves resistance and friction can be modeled as:
hf=(Kv^2)/2gWhere K is the resistance coefficient, f is the Darcy
friction factor, V is the velocity and hf is the Frictional Loss or Head Loss.
Considering using a Gate valve for purposes of the design.● Resistance will have to be tested manually
○ Test each resistor position and correlate them to the pressure output seen
■ Create a graph of resistor position vs pressure output
Valve ConsiderationsOther potentials: Linear Actuator and Globe Valve
Resistance BOM
Subsystem
Component ID Component Supplier
Supplier ID
Quanitity / Dimensions Price/Unit Total Cost Notes
Valve V1
Bronze Gate Valve-Class 125, 3/4" NPT Female, Non-rising Stem
McMaster Carr 4619K14 1 $27.96 $27.96
May be alternated for linear actuator
SubsystemComponent
ID Component SupplierSupplier
IDQuanitity /
Dimensions Price/Unit Total Cost Notes
Linear Actuator LA1
25mm Diamter Actuator Exteded strew with motor
Anaheim Automation
TSFCA25-150-21-023-LW4 11 $39.00 $39.00
Can only apply 10 Newtons of Force.
Globe Valve GV
Low-Pressure Bronze Globe Valve, 3/4" NPT Female, EPDM Disc
McMaster Carr 4695K65 1 $37.44 $37.44
Meant for low pressure flows, overall length of 2 5/16”
Current BOM
Alternative BOM
Resistance Risks
Resistance - Preliminary Testing Plans1.Calibration
a. Make sure when impedance is 0 R=ΔP/F is obeyed.
b. Make sure when impedance is at max there is no flow through the
system after this point.
2.Calculate theoretical head loss through circuit and perform
head loss experiment on the pipe and valve to confirm
compliance to the theoretical model (initial set up for
MSD)
LabVIEW
LabVIEW Considerations
• Waveform consistency
• Same parameters give
same waveforms each
time
• Interfacing with pressure
sensors
• One program for both
teams
F. M. Donovan (1975) Design of a Hydraulic Analog of the Circulatory System for Evaluating Artificial Hearts, Biomaterials, Medical Devices, and Artificial Organs, 3:4, 439-449
Arterial
Venous
Preliminary Life Span Calculation
Considerations:
What will likely fail first?
Is that part expensive?
Is that part easy to replace?
New risks
Mitigated Risks
Risk Chart
Draft System Bill of Materials (1 of 2)
Draft System Bill of Materials (2 of 2)
Project Plan - what we achieved
Project Plan - deliverables for next phase
End of MSD I Deliverables1. “Working” theoretical model
2. Finalized, completed and accurately priced Bill of Materials
3. CAD drawing 100% done
4. Test plan for design 90% complete
5. Theoretical risk list complete with ideas as to how to minimize
potential effects
6. Understanding of deliverables for MSD II
7. Short list of contests this design could enter
Ways to Improve Efficiency
1. More organized direction for research of parts and
materials
2. Better collaboration with P16080
3. More organized group meetings
Goals for Phase IV
1. Choose the most efficient pressure sensor
2. Decide on dimensions for compliance tanks
3. Decide on internal versus external resistances
4. Interactions with P16080
• LabVIEW
• Flow meter
• Interfacing
ASEE 123rd Annual Conference & Exposition
• Abstract submitted on October 20th, 2015
• Abstract decision deadline: November 9, 2015